CCAPD: Alignment of Catalase

10 20 30 40 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx =============================================================================== * S_CEREVISIAE -----------sk--------lgqeknevnys------------- * Candida_albicans --------------------------------------------- * Candida_dubliniensis --------------------------------------------- * Candida_glabrata ------------------------sanptnts------------- * Candida_tropicalis --------------------------------------------- * Debaryomyces_hansenii --------------------------------------------- * Eremothecium_gossypii ----------------------agnndktnsa------------- * Kluyveromyces_lactis -------------------------ghptnta------------- =============================================================================== * BOVINE -----------ad--------nrdpasdqmkhwkeqraa------ * HUMAN -----------ad--------srdpasdqmqhwkeqraa------ * Anopheles_gambiae --------------------------------------l------ * Apis_mellifera -----------tei-------krnpsadqlidykknlk------- * Ascaris_lumbricoides --------p--qt--------kgkpheeqleqyknsqt------- * Bombyx_mandarina ------------a--------srdpatdqlinyk-ktlk------ * C_elegans ---------------------pndpsdnqlktyketypvslefkg * Canis_lupus -----------ad--------srdpasdqmklwkeqraa------ * Cavia_porcellus -----------ad--------srdpasdqmkhwkeeraa------ * Danio_rerio -----------ad--------drekstdqmklwkegrgs------ * D_melanogaster ------------a--------grdaasnqlidyknsqtv------ * D_pseudoobscura ------------a--------ardaasnqlidykntqtv------ * Chicken -----------ad--------grdvaseqlkrwqsqrgs------ * Litopenaeus_vannamei ---------------------prdkcaeqlndfkkqqta------ * Pongo_pygmaeus -----------ad--------srdpasdqmkhwkeqraa------ * Rat -----------ad--------srdpasdqmkqwkeqrap------ * Pig -----------ad--------nrdpasdqmkhwkeqraa------ * X_laevis -----------ad--------krdnaadqmklwkngrgs------ * X_tropicalis -----------ad--------krdnaadqmklwkesrgs------ * Mouse-CATA -----------sd--------srdpasdqmkqwkeqras------ * Mouse-Q3TXQ6 -----------sd--------srdpasdqmkqwkeqras------ =============================================================================== B PROTEUS_MIRABILIS -----------ek-------------------------------- B 1H6NA_Proteus_mirabilis --------------------------------------------- B 1H7KA_Proteus_mirabilis --------------------------------------------- B Acinetobacter_calcoaceticus nd---------dt-------------------------------- B Actinobacillus_pleuropneumoniae --------------------------------------------- B Actinobacillus_succinogenes seskcpf----hh-------------------------------- B Bordetella_pertussis nam--------tn-------------------------------- B Chromobacterium_violaceum -----------rk-------------------------------- B Colwellia_psychrerythraea ------------k-------------------------------- B Cupriavidus_metallidurans --------------------------------------------- B Desulfotalea_psychrophila kd---------ek-------------------------------- B Haemophilus_influenzae ssqcpfshl--aa-------------------------------- B Neisseria_gonorrhoeae ttskc------pv-------------------------------- B Neisseria_meningitidis ttskc------pv-------------------------------- B Nitrosomonas_europaea dd---------ak-------------------------------- B Nitrosomonas_eutropha dd---------sk-------------------------------- B Photorhabdus_luminescens -----------kk-------------------------------- B Pseudomonas_aeruginosa e----------ek-------------------------------- B Streptomyces_coelicolor pen--------nq-------------------------------- B Vibrio_fischeri ------------s-------------------------------- B Vibrio_parahaemolyticus -----------tn-------------------------------- B Yersinia_pestis ms---------kk-------------------------------- =============================================================================== B MICROCOCCUS_LUTEUS ---------eh---qkttpha------------------------ B Thermobifida_fusca ketdltetnea---lstasna------------------------ =============================================================================== B HELICOBACTER_PYLORI ---------vn---kd----------------------------- B Helicobacter_pylori-CAA94567 ---------vn---kd----------------------------- B Helicobacter_pylori-CATA ---------vn---kd----------------------------- B Helicobacter_pylori-CATA_HELPJ ---------vn---kd----------------------------- =============================================================================== B ENTEROCOCCUS_FAECALIS ---------kn---------------------------------- B Bacillus_licheniformis -------ttnk---------------------------------- B Bacillus_subtilis ---------ss---------------------------------- B Oceanobacillus_iheyensis -------snkr---------------------------------- =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 50 60 70 80 90 ----|----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxlxxxxxTtxxGxPVxE =============================================================================== * S_CEREVISIAE --------------------d-v------redrvvTnstGnPInE * Candida_albicans -------------------------------aptfTnsnGqPIpE * Candida_dubliniensis -------------------------------aptfTnsnGqPIpE * Candida_glabrata --------------------d-v------rgdrvvTnstGyPynD * Candida_tropicalis -------------------------------aptfTnsnGqPIpE * Debaryomyces_hansenii -------------------------------apvyTnsnGcPIpE * Eremothecium_gossypii --------------------e-v------redrvvTnsvGnPInE * Kluyveromyces_lactis --------------------d-v------rkdrvvTnsqGaPInE =============================================================================== * BOVINE ----------------qkp-dv-------L-----TTggGnPVgD * HUMAN ----------------qka-dv-------L-----TTgaGnPVgD * Anopheles_gambiae ----------------qdk-vt-------a-----TmshGaPVgt * Apis_mellifera ----------------pdc-pi-------f-----lTgsGtPIsK * Ascaris_lumbricoides -----------------kp-fv-------L-----TTsnGaPIfn * Bombyx_mandarina ----------------dsp-gf-------I-----TTksGaPVgi * C_elegans tdafstttttiysnlfqkp-qv-------I-----TTsnGaPIys * Canis_lupus ----------------qkp-dv-------L-----TTggGnPIgD * Cavia_porcellus ----------------qkp-dv-------L-----TTagGnPVgD * Danio_rerio ----------------qrp-dv-------L-----TTgaGvPIgD * D_melanogaster ----------------s-p-ga-------I-----TTgnGaPIgi * D_pseudoobscura ----------------s-p-gs-------I-----TTghGsPIgi * Chicken ----------------qkp-da-------L-----TTgaGnPIgD * Litopenaeus_vannamei ------------------p-dn-------L-----TTshGcPLaD * Pongo_pygmaeus ----------------qka-dv-------L-----TTgaGnPVgD * Rat ----------------qkp-dv-------L-----TTggGnPIgD * Pig ----------------qkp-di-------L-----TTgsGnPIgD * X_laevis ----------------qkp-dv-------L-----TTggGnPIsD * X_tropicalis ----------------qkp-dv-------L-----TTggGnPIsD * Mouse-CATA ----------------qrp-dv-------L-----TTggGnPIgD * Mouse-Q3TXQ6 ----------------qrp-dv-------L-----TTggGnPIgD =============================================================================== B PROTEUS_MIRABILIS --------------------k-k------L-----TTaaGaPVvD B 1H6NA_Proteus_mirabilis --------------------k-k------L-----TTaaGaPVvD B 1H7KA_Proteus_mirabilis --------------------k-k------L-----TTaaGaPVvD B Acinetobacter_calcoaceticus --------------------k-kcpfsq-L-----TTdfGaPVvD B Actinobacillus_pleuropneumoniae -------------------------------------nnGaPVvD B Actinobacillus_succinogenes --------------------t-s------L-----TmnnGaPVvD B Bordetella_pertussis --------------------k-t------L-----TTaaGaPVaD B Chromobacterium_violaceum --------------------h-t------L-----TTaaGaPVvD B Colwellia_psychrerythraea --------------------k-k------L-----TTnaGcPVan B Cupriavidus_metallidurans --------------------n-k------L-----TTafGaPVvD B Desulfotalea_psychrophila --------------------d-k------L-----TgnnGaPVvD B Haemophilus_influenzae --------------------t-n------L-----TmgnGaPVaD B Neisseria_gonorrhoeae --------------------t-h------L-----TmnnGaPVaD B Neisseria_meningitidis --------------------t-h------L-----TmnnGaPVaD B Nitrosomonas_europaea --------------------k-k------L-----TTsaGaPVaD B Nitrosomonas_eutropha --------------------r-k------L-----TTsaGaPVpD B Photorhabdus_luminescens --------------------r-g------L-----TTnaGtPVvD B Pseudomonas_aeruginosa --------------------t-r------L-----TTaaGaPVvD B Streptomyces_coelicolor --------------------k-p------L-----TTvaGaPVpD B Vibrio_fischeri --------------------k-k------L-----TTaaGcPVah B Vibrio_parahaemolyticus --------------------k-k------L-----TTaaGcPVah B Yersinia_pestis --------------------k-g------L-----TTaaGaPVvD =============================================================================== B MICROCOCCUS_LUTEUS -------------------t-g------s------TrqnGaPavs B Thermobifida_fusca -------------------t-g------s------TldsGaPaas =============================================================================== B HELICOBACTER_PYLORI -------------------v-k------q------TTafGaPVwD B Helicobacter_pylori-CAA94567 -------------------v-k------q------TTafGaPVwD B Helicobacter_pylori-CATA -------------------v-k------q------TTafGaPVwD B Helicobacter_pylori-CATA_HELPJ -------------------v-k------q------TTafGaPVwD =============================================================================== B ENTEROCOCCUS_FAECALIS -------------------q-h------l------TTsqGsPVgD B Bacillus_licheniformis -------------------n-n------l------TTswGaPVgD B Bacillus_subtilis -------------------n-k------l------TTswGaPVgD B Oceanobacillus_iheyensis -------------------n-t------l------TTasGaPVgD =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxlxxxxxTtxxGxPVxE 100 110 120 130 ----:----|----:----|----:----|----:----|----: Consensus xxsxiTaGpRGPVLLQDIxflEKLANFDRErIPERvVHAKGsGAY =============================================================================== * S_CEREVISIAE pfvtqriGehGPLLLQDynlIDsLAHFNREnIPQRnpHAhGSGAF * Candida_albicans pfatqrvGqhGPLLLQDfnlIDsLAHFDRERIPERVVHAKGSGAY * Candida_dubliniensis pfatqrvGqhGPLLLQDfnlIDsLAHFDRERIPERVVHAKGSGAY * Candida_glabrata pfatqrvGqhGPLLMQDanlIDsLAHFNRERIPERnpHAhGSGAF * Candida_tropicalis pfatqrvGqhGPLLLQDfnlIDsLAHFDRERIPERVVHAKGSGAY * Debaryomyces_hansenii pfatqrvGqhGPLLLQDfnlIDsLAHFDRERIPERVVHAKGSGAY * Eremothecium_gossypii pfatqrvGqhGPLLLQDynlLDlLAHFNRERVPERnpHAhGSGAF * Kluyveromyces_lactis pfatqrvGqhGPLLLQDfnlLDsLAHFNRERIPERnpHAhGSGAF =============================================================================== * BOVINE klNsLTvGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * HUMAN klNvITvGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Anopheles_gambiae ktaseTAGPRGPVLLQDVhlIDELAHFDRERIPERVVHAKGaGAF * Apis_mellifera kaS-LTvGPnGPILLQDyvFLDELsHFNRERIPERVVHAKGaGAF * Ascaris_lumbricoides kkasLTvGPRGPLLLQDVvFLDEMAHFDRERIPERVVHAKGgGAh * Bombyx_mandarina ktaiqTvGknGPaLLQDVnFLDEMsSFDRERIPERVVHAKGaGAF * C_elegans ktavLTAGrRGPMLMQDVvYMDEMAHFDRERIPERVVHAKGaGAh * Canis_lupus klNvMTAGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Cavia_porcellus klNiMTvGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Danio_rerio klNaMTAGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * D_melanogaster kdasqTvGPRGPILLQDVnFLDEMsHFDRERIPERVVHAKGaGAF * D_pseudoobscura kdatqTvGPRGPVLLQDVnFLDEMAHFDRERIPERVVHAKGaGAF * Chicken klNiMTvGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Litopenaeus_vannamei klNsLTvGPRGPILLQDIqlLDEMAHFDRERIPERVVHAKGaGAF * Pongo_pygmaeus klNvITvGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Rat klNiMTAGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Pig klNiLTAGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * X_laevis klNlLTvGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * X_tropicalis klNlLTvGPRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Mouse-CATA klNiMTAGsRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF * Mouse-Q3TXQ6 klNiMTAGsRGPLLVQDVvFtDEMAHFDRERIPERVVHAKGaGAF =============================================================================== B PROTEUS_MIRABILIS nnNvITAGPRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSGAF B 1H6NA_Proteus_mirabilis nnNvITAGPRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSGAF B 1H7KA_Proteus_mirabilis nnNvITAGPRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSGAF B Acinetobacter_calcoaceticus nqNsMTAGaRGPLLaQDLwlnEKLANFvREvIPERrMHAKGSGAF B Actinobacillus_pleuropneumoniae nqNsMTAGPRGPLLaQDLwlnEKLANFvREvIPERrMHAKGSGAF B Actinobacillus_succinogenes nqNsMTAGPRGPLLaQDLwlnEKLANFvREvIPERrMHAKGSGAF B Bordetella_pertussis nnNtMTAGPRGPaLLQDVwFLEKLAHFDRERIPERVVHAKGSGAY B Chromobacterium_violaceum nqNvqTAGPRGPMLLQDVwYLEKLAHFDREvIPERrMHAKGSGAF B Colwellia_psychrerythraea nqNvMTAGPRGPqLLQDVwFLEKLAHFDREvIPERrMHAKGSGAY B Cupriavidus_metallidurans nqNvqTAGPRGPaLLQDVwFLEKLAHFDREvIPERrMHAKGaGAY B Desulfotalea_psychrophila nqNvMTAGPRGPLLLQDVwFMEKLAHFDREvIPERrMHAKGSGAY B Haemophilus_influenzae nqNsLTAGPRGPLLaQDLwlnEKLADFvREvIPERrMHAKGSGAF B Neisseria_gonorrhoeae nqNsLTAGPRGPLLtQDLwlnEKLADFvREvIPERrMHAKGSGAF B Neisseria_meningitidis nqNsLTAGPRGPLLaQDLwlnEKLADFvREvIPERrMHAKGSGAF B Nitrosomonas_europaea nqNvMTAGPRGPMLLQDIwFLEKLAHFDREvIPERrMHAKGSGAY B Nitrosomonas_eutropha nqNvMTAGPRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSGAY B Photorhabdus_luminescens nnNvMTAGqRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSGAh B Pseudomonas_aeruginosa nqNvqTAGPRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSaAY B Streptomyces_coelicolor nqNsLTsGPRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSGAF B Vibrio_fischeri nqNvqTAGkRGPqLLQDVwFLEKLAHFDREvIPERrMHAKGSGAY B Vibrio_parahaemolyticus nqNvMTAGPRGPqLLQDVwFLEKLAHFDREvIPERrMHAKGSGAY B Yersinia_pestis nnNvITAGrRGPMLLQDVwFLEKLAHFDREvIPERrMHAKGSGAY =============================================================================== B MICROCOCCUS_LUTEUS drqsLTvGseGPIVLhDthlLEthqHFNRmnIPERrpHAKGSGAF B Thermobifida_fusca drNsLSvGsnGPLLLhDVrlVEtLAHFNRERVPERnpHAKGaGAF =============================================================================== B HELICOBACTER_PYLORI dnNvITAGPRGPVLLQstwFLEKLAaFDRERIPERVVHAKGSGAY B Helicobacter_pylori-CAA94567 dnNvITAGPRGPVLLQstwFLEKLAaFDRERIPERVVHAKGSGAY B Helicobacter_pylori-CATA dnNvITAGPRGPVLLQstwFLEKLAaFDRERIPERVVHAKGSGAY B Helicobacter_pylori-CATA_HELPJ dnNvITAGPRGPVLLQstwFLEKLAaFDRERIPERVVHAKGSGAY =============================================================================== B ENTEROCOCCUS_FAECALIS nqNsLTAGefGPVLIQDVhlLEKLAHFNRERVPERVVHAKGaGAh B Bacillus_licheniformis nqNsMTAGsRGPtLIQDVhlLEKLAHFNRERVPERVVHAKGaGAh B Bacillus_subtilis nqNsMTAGsRGPtLIQDVhlLEKLAHFNRERVPERVVHAKGaGAh B Oceanobacillus_iheyensis nqNsITAGhnGPtLLQDfhlLEKLAHFNRERIPERVVHAKGaGAh =============================================================================== Consensus xxsxiTaGpRGPVLLQDIxflEKLANFDRErIPERvVHAKGsGAY 140 150 160 170 180 ----|----:----|----:----|----:----|----:----| Consensus GxFeVxSNDISQFtKAkIFneVGKKTxMfiRFSTVaGExGsADsx =============================================================================== * S_CEREVISIAE GyFEV-TDDITdicgsaMFSKIGKRTkcltRFSTVgGDkGSADTv * Candida_albicans GvFEV-TDDITdicaAKflDtVGKKTrIFtRFSTVgGElGSADTa * Candida_dubliniensis GvFEV-TDDITdvcaAKflDtVGKKTrVFtRFSTVgGElGSADTa * Candida_glabrata GyFEV-TDDITdicgsaMFSEIGKRTrfltRFSTVgGEkGSADTa * Candida_tropicalis GvFEV-TDDITdicaAKflDtVGKKTrIFtRFSTVgGEaGSADTa * Debaryomyces_hansenii GyFEV-TDDISdvcsAaflDtIGKKTkVltRFSTVgGEsGSADSa * Eremothecium_gossypii GyFEV-TDDITdvcgsaMFgEVGKRTralVRFSTVgGEkGSADTv * Kluyveromyces_lactis GylEI-TDDITdvcgsaMFDtVGKRTrclVRFSTVgGEkGSADTa =============================================================================== * BOVINE GyFEV-THDITRYSKAKVFehIGKRTpIaVRFSTVAGEsGSADTv * HUMAN GyFEV-THDITKYSKAKVFehIGKKTpIaVRFSTVAGEsGSADTv * Anopheles_gambiae GyFEV-THDITQYcaAKLFeKVGKKTpLaVRFSTVgGEsGSADTv * Apis_mellifera GyFEV-THDITKYSKAKVFSsIGKRTpIaVRFSTVgGEsGSADTv * Ascaris_lumbricoides GfFEV-TDDITKYcKAdVFStIGKRTpIFIRFSTVgGElGSADTq * Bombyx_mandarina GyFEV-THDITKYSaAKVFesIGKRTpIaVRFSTVgGEsGSADTv * C_elegans GyFEV-THDISKYcKAdIFNKVGKQTpLlIRFSTVgGEsGSADTa * Canis_lupus GyFEV-THDITKYSKAKVFehIGKRTpIaVRFSTVAGEsGSADTv * Cavia_porcellus ayFEV-THDITKYcKAKVFehIGKKTpIaVRFSTVAGEsGSADTv * Danio_rerio GyFEV-THDITRYSKAKVFehVGKtTpIvVRFSTVAGEaGSpDTv * D_melanogaster GyFEV-THDITQYcaAKIFDKVkKRTpLaVRFSTVgGEsGSADTa * D_pseudoobscura GyFEV-THDISKYcaAKMFDKVkKRTpLaIRFSTVgGEsGSADTa * Chicken GyFEV-THDITKYcKAKVFehIGKRTpIaIRFSTVAGEsGSADTv * Litopenaeus_vannamei GyFEV-THDISKYcKAaLFSEIGKRTpIaVRYSTVgGEsGStDTa * Pongo_pygmaeus GyFEV-THDITKYSKAKVFehIGKKTpIaVRFSTVAGEsGSADTv * Rat GyFEV-THDITRYSKAKVFehIGKRTpIaVRFSTVAGEsGSADTv * Pig GyFEV-THDITRFSKAKVFehVGKRTpIaVRFSTVAGEsGSADTv * X_laevis GycEV-THDITKYSKAKVFenIGKRTpIaVRFSTVAGEaGSsDTv * X_tropicalis GyFEI-THDITKYSKAKVFehIGKRTpIaIRFSTVAGEsGSADTv * Mouse-CATA GyFEV-THDITRYSKAKVFehIGKRTpIaVRFSTVAGEsGSADTv * Mouse-Q3TXQ6 GyFEV-THDITRYSKAKVFehIGKRTpIaVRFSTVtGEsGSADTv =============================================================================== B PROTEUS_MIRABILIS GtFtV-THDITKYTRAKIFSEVGKKTeMFaRFSTVAGErGaADae B 1H6NA_Proteus_mirabilis GtFtV-THDITKYTRAKIFSEVGKKTeMFaRFSTVAGErGaADae B 1H7KA_Proteus_mirabilis GtFtV-THDITKYTRAKIFSEVGKKTeMFaRFSTVAGErGaADae B Acinetobacter_calcoaceticus GtFtV-THDITQYTRAKIFSEIGKKTeMFaRFTTVAGErGaADae B Actinobacillus_pleuropneumoniae GkFtV-THDITQYTKAaIFSEVGKETeLFaRFTTVAGErGaADae B Actinobacillus_succinogenes GkFtV-TNDITQYTKAaIFSEVGKETeLFVRFTTVAGErGaADae B Bordetella_pertussis GtFtV-THDISRYTRARIFaEVGKQTpLFLRFSTVAGErGaADae B Chromobacterium_violaceum GtFtV-THDITRYTRAaLFSDIGKKTdLFLRFSTVAGErGaADae B Colwellia_psychrerythraea GtFtV-THDITQYTRAKIFSEVGKKTeMFaRFTTVAGErGaADae B Cupriavidus_metallidurans GtFtV-THDITKYTRAnLFSQVGKKTdLFLRFSSVAGErGaADae B Desulfotalea_psychrophila GtFtV-TDDIraYTKAKIFaEIGKtTdLFVRFSTVAGErGaADae B Haemophilus_influenzae GtFtV-THDITKYTRAKIFSEVGKKTeMFaRFTTVAGErGaADae B Neisseria_gonorrhoeae GtFtV-THDITKYTRAKIFSEVGKKTeMFaRFTTVAGErGaADae B Neisseria_meningitidis GtFtV-THDITKYTRAKIFSEVGKKTeMFaRFTTVAGErGaADae B Nitrosomonas_europaea GtFtV-THDITRYTRAnIFSQIGKKTdLFVRFSTVAGErGaADae B Nitrosomonas_eutropha GtFtV-THDITRYTQAKIFSQIGKKTeLFVRFSTVAGErGaADae B Photorhabdus_luminescens GvFvV-THDITKYTRAKIFSEIGKKTeMFaRFSTVAGErGaADae B Pseudomonas_aeruginosa GtFtV-THDITpYTRAKIFSQVGKKTdMFLRFSTVAGErGaADae B Streptomyces_coelicolor GtFtV-THDITRYTsAKIFSEIGKKTpLFtRFSTVAGErGaADae B Vibrio_fischeri GtFtV-THDITKYTKAKLFSEIGKQTeLFaRFTTVAGErGaADae B Vibrio_parahaemolyticus GtFtV-THDITKYTRAKIFSEVGKKTeLFaRFTTVAGErGaADae B Yersinia_pestis GtFtV-THDITQYTRAKIFSEIGKKTdMFVRFSTVAGErGaADae =============================================================================== B MICROCOCCUS_LUTEUS GeFEV-TeDVSKYTKAlVFqp-GtKTetlLRFSTVAGElGSpDTw B Thermobifida_fusca GvFEt-TeDVSQYTKAaLFqK-GaRTeMlaRFSTVAGEqGSpDTw =============================================================================== B HELICOBACTER_PYLORI GtFtV-TkDITKYTKAKIFSKVGKKTecFfRFSTVAGErGSADav B Helicobacter_pylori-CAA94567 GtFtV-TkDITKYTKAKIFSKVGKKTecFfRFSTVAGErGSADav B Helicobacter_pylori-CATA GtFtV-TkDITKYTKAKIFSKVGKKTecFfRFSTVAGErGSADav B Helicobacter_pylori-CATA_HELPJ GtFtV-TkDITKYTKAKIFSKVGKKTecFfRFSTVAGEkGSADav =============================================================================== B ENTEROCOCCUS_FAECALIS GiFKV-SqsMaQYTKAdflSEVGKETpLFaRFSTVAGElGSsDTl B Bacillus_licheniformis GyFEV-TNDVSKYTKAKflSEVGKRTpLFVRFSTVAGEnGSADSv B Bacillus_subtilis GyFEV-TNDVTKYTKAaflSEVGKRTpLFIRFSTVAGElGSADTv B Oceanobacillus_iheyensis GyFEVtNDEISKYTKAdflSEkGKRTdMFIRFSTVAGEqGSADTv =============================================================================== Consensus GxFeVxSNDISQFtKAkIFneVGKKTxMfiRFSTVaGExGsADsx 190 200 210 220 ----:----|----:----|----:----|----:----|----: Consensus RDpRGFAMKFYTEEGNWDLVGNNTPVFFIRDpikFPNfiHsqKRN =============================================================================== * S_CEREVISIAE RDPRGFAtKFYTEEGNlDwVyNNTPVFFIRDPsKFPHFIHTQKRN * Candida_albicans RDPRGFAtKiYTEEGNlDLVyNNTPVFFIRDPsKFPHFIHTQKRN * Candida_dubliniensis RDPRGFAtKFYTEEGNlDLVyNNTPVFFIRDPsKFPHFIHTQKRN * Candida_glabrata RDPRGFAtKFYTEEGNlDwVyNNTPIFFIRDPsKFPHFIHTQKRN * Candida_tropicalis RDPRGFAtKFYTEEGNlDLVyNNTPVFFIRDPsKFPHFIHTQKRN * Debaryomyces_hansenii RDPRGFstKlYTEEGNlDLVyNNTPVFFIRDPsKFPHFIHTQKRN * Eremothecium_gossypii RDPRGFAVKFYTEEGNlDwVyNNTPVFFIRDPsKFPHFIHTQKRN * Kluyveromyces_lactis RDPRGFAIKFYSEEGNvDwVnNNTPVFFIRDPsKFPHFIHTQKRN =============================================================================== * BOVINE RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDaLlFPSFIHSQKRN * HUMAN RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPIlFPSFIHSQKRN * Anopheles_gambiae RDPRGFAVKFYTDDGvWDMVGNNTPIFFIRDPVlFPSFIHTQKRN * Apis_mellifera RDPRGFAVKFYTEEGvWDLVGNNTPIFFIKDPIyFPSFIHTQKRN * Ascaris_lumbricoides RDPRGFAIKFYTEEGNWDLVGNNTPIFFIRDPIfFPNFIHTQKRN * Bombyx_mandarina RDPRGFAVKFYTDDGvWDLVGNNTPIFFIRDPtlFPSFIHTQKRN * C_elegans RDPRGFAIKFYTEEGNWDLVGNNTPIFFIRDPIhFPNFIHTQKRN * Canis_lupus RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDaIlFPSFIHSQKRN * Cavia_porcellus RDPRGFAVKFYTEEGiWDLVGNNTPIFFIRDaLlFPSFIHSQKRN * Danio_rerio RDPRGFAVKFYTDEGNWDLtGNNTPtFFIRDtLlsPSFIHSQKRN * D_melanogaster RDPRGFAVKFYTEDGvWDLVGNNTPVFFIRDPIlFPSFIHTQKRN * D_pseudoobscura RDPRGFAVKFYTEDGvWDLVGNNTPIFFIRDPIlFPSFIHTQKRN * Chicken RDPRGFAMKFYTEEGNWDLVGNNTPIFFIRDaMlFPSFIHSQKRN * Litopenaeus_vannamei RDPRGFAVKFYTEEGNWDLVGNNTPIFFIRDPIlFPSFIHTQKRN * Pongo_pygmaeus RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPLlFPSFIHSQKRN * Rat RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDaMlFPSFIHSQKRN * Pig RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDaIlFPSFIHSQKRN * X_laevis RDPRGFAVKmYTEDGNWDLtGNNTPVFFIRDaMlFPSFIHSQKRN * X_tropicalis RDPRGFAVKmYTEDGNWDLtGNNTPVFFIRDaMlFPSFIHSQKRN * Mouse-CATA RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDaIlFPSFIHSQKRN * Mouse-Q3TXQ6 RDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDaIlFPSFIHSQKRN =============================================================================== B PROTEUS_MIRABILIS RDiRGFALKFYTEEGNWDMVGNNTPVFYLRDPLKFPDlnHivKRD B 1H6NA_Proteus_mirabilis RDiRGFALKFYTEEGNWDMVGNNTPVFYLRDPLKFPDlnHivKRD B 1H7KA_Proteus_mirabilis RDiRGFALKFYTEEGNWDMVGNNTPVFYLRDPLKFPDlnHivKRD B Acinetobacter_calcoaceticus RDiRGFALKFYTEEGNWDMVGNNTPVFFLRDPrKFPDlnkavKRD B Actinobacillus_pleuropneumoniae RDiRGFAVKFYTEQGNWDfVGNNTPVFFLRDPrKFPDlnkavKRD B Actinobacillus_succinogenes RDiRGFAVKFYTEQGNWDLVGNNTPVFFLRDPrKFPDlnkavKRD B Bordetella_pertussis RDvRGFAIKFYTDEGNWDLVGNNTPVFFIRDPLKFPDFIHTQKRD B Chromobacterium_violaceum RDiRGFAVKFYTEEGNWDLVGNNTPVFFLRDPLKFPDlnravKRN B Colwellia_psychrerythraea RDiRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDlnHavKRD B Cupriavidus_metallidurans RDiRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDlnHavKRD B Desulfotalea_psychrophila RDiRGFAMKFYTEEGNWDLVGNNTPVFFLKDPLKFPDlnHavKRD B Haemophilus_influenzae RDiRGFALKFYTEEGNWDLVGNNTPVFFLRDPrKFPDlnkavKRD B Neisseria_gonorrhoeae RDiRGFALKFYTEEGNWDVVGNNTPVFFLRDPrKFPDlnkavKRD B Neisseria_meningitidis RDiRGFALKFYTEEGNWDVVGNNTPVFFLRDPrKFPDlnkavKRD B Nitrosomonas_europaea RDiRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDlnHavKRD B Nitrosomonas_eutropha RDiRGFAIKFYTEEGNWDLVGNNTPVFFLRDPLKFPDlnHavKRD B Photorhabdus_luminescens RDiRGFALKFYTEEGNWDLVGNNTPIFYLRDPLKFPDlnHvvKRD B Pseudomonas_aeruginosa RDiRGFsMRFYTEQGNWDLVGNNTPVFYLRDPLKFPDlnHvvKRD B Streptomyces_coelicolor RDiRGFAVKFYTDEGNWDLVGNNTPVFFfRDPLKFPDlnHavKRD B Vibrio_fischeri RDiRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDlnHavKRD B Vibrio_parahaemolyticus RDiRGFALKFYTEEGNWDLVGNNTPVFFLRDPLKFPDlnHavKRD B Yersinia_pestis RDiRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDlnHvvKRD =============================================================================== B MICROCOCCUS_LUTEUS RDvRGFALRFYTEEGNYDLVGNNTPIFFLRDPMKFtHFIrSQKRl B Thermobifida_fusca RDvRGFALKFYTsEGNYDLVGNNTPIFFVRDPMKFPHFIrSQKRm =============================================================================== B HELICOBACTER_PYLORI RDPRGFAMKYYTEEGNWDLVGNNTPVFFIRDaIKFPDFIHTQKRD B Helicobacter_pylori-CAA94567 RDPRGFAMKYYTEEGNWDLVGNNTPVFFIRDaIKFPDFIHTQKRD B Helicobacter_pylori-CATA RDPRGFAMKYYTEEGNWDLVGNNTPVFFIRDaIKFPDFIHTQKRD B Helicobacter_pylori-CATA_HELPJ RDPRGFAMKYYTEEGNWDLVGNNTPVFFIRDaIKFPDFIHTQKRD =============================================================================== B ENTEROCOCCUS_FAECALIS RDPRGFALKFYTDEGNYDLVGNNTPIFFIRDaIKFPDFIHSQKRN B Bacillus_licheniformis RDPRGFAVKFYTEEGNYDLVGNNTPVFFIRDaIKFPDFIHTQKRH B Bacillus_subtilis RDPRGFAVKFYTEEGNYDIVGNNTPVFFIRDaIKFPDFIHTQKRD B Oceanobacillus_iheyensis RDPRGFAVKFYTEEGNYDLVGNNTPIFFIRDaIKFPDFIHTQKRN =============================================================================== Consensus RDpRGFAMKFYTEEGNWDLVGNNTPVFFIRDpikFPNfiHsqKRN 230 240 250 260 270 ----|----:----|----:----|----:----|----:----| Consensus PQTNLRNxnmxWDFfSlxPExxsLHQVtiVfSDRGIPxsYRNMNG =============================================================================== * S_CEREVISIAE PQTNLRDaDMfWDFlTtpenqvaIHQVmILFSDRGtPaNYRSMHG * Candida_albicans PETHLKDaNMfWDYlTs-n-eeSIHQVmVLFSDRGtPaSYReMNG * Candida_dubliniensis PETHLKDaNMfWDYlTs-n-eeSIHQVmILFSDRGtPaSYReMNG * Candida_glabrata PQTNLKDpNMfWDYlTtpenqvaVHQLmILFSDRGtPaSYRHMNG * Candida_tropicalis sETHLKDaNMfWDYlTs-n-eeSnHQVmILFSDRGtPaSYReMNG * Debaryomyces_hansenii PETHLKDptMfWDYlTs--nqeSIHQVmtLFSDRGtPaSYReMNG * Eremothecium_gossypii PRTNLKDaNMfWDFlTtpenqvaIHQVmILFSDRGIPaSYRHMNG * Kluyveromyces_lactis PETNMKDaDMfWDFlTteenqvaIHQVmILFSDRGtPaSYRNMNs =============================================================================== * BOVINE PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMDG * HUMAN PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG * Anopheles_gambiae PaTHLKDpDMfWDFiSLrPE--TtHQtmfLFSDRGtPdgYRfMNG * Apis_mellifera PvTHLKDaDMfWDFlSLrPE--StHQVmfLFSDRGIPdgYRHMNG * Ascaris_lumbricoides PvTHLKDpNMmWDFFSLrPE--TtHQVmILFgDRGIPdgFRHMDG * Bombyx_mandarina PaTHLKDpDMfWDllTLrPE--TIHQLlyLFgDRGIPdgYRHMNG * C_elegans PQTHLKDpNMiFDFWlhrPE--aLHQVmfLFSDRGLPdgYRHMNG * Canis_lupus PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG * Cavia_porcellus PQTHLKDpDMmWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG * Danio_rerio PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdgYRHMNG * D_melanogaster PQTHLKDpDMfWDFlTLrPE--SaHQVcILFSDRGtPdgYcHMNG * D_pseudoobscura PQTHLKDpDMfWDFlTLrPE--StHQVcfLFgDRGtPdgYcHMNG * Chicken PQTHLKDpDMvWDFlSLrPE--SLHQVSfLYSDRGIPdgFRHMNG * Litopenaeus_vannamei PaTHLKDcDMfWDFiSLrPE--TtHQVSfLFSDRGtPdgYRHMNG * Pongo_pygmaeus PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG * Rat PQTHLKDpDMvWDFWSLcPE--SLHQVTfLFSDRGIPdghRHMNG * Pig PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG * X_laevis PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG * X_tropicalis PQTHLKDpDMvWDFWaLrPE--SLHQVSfLFSDRGIPdghRHMNG * Mouse-CATA PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG * Mouse-Q3TXQ6 PQTHLKDpDMvWDFWSLrPE--SLHQVSfLFSDRGIPdghRHMNG =============================================================================== B PROTEUS_MIRABILIS PRTNMRNmaykWDFFShlPE--SLHQLTIdmSDRGLPlSYRfVHG B 1H6NA_Proteus_mirabilis PRTNMRNmaykWDFFShlPE--SLHQLTIdmSDRGLPlSYRfVHG B 1H7KA_Proteus_mirabilis PRTNMRNmaykWDFFShlPE--SLHQLTIdmSDRGLPlSYRfVHG B Acinetobacter_calcoaceticus PKTNLRSatnnWDFWTLlPE--aLHQVTIVmSDRGIPaSYRHMHG B Actinobacillus_pleuropneumoniae PRTNMRSatnnWDFWTLlPE--afHQVTIVmSERGIPaSYRHMHG B Actinobacillus_succinogenes PRTNMRSaNnnWDFWTLlPE--aLHQVTIVmSERGIPaSYRHMHG B Bordetella_pertussis PKTNLRNataaWDFWSLnPE--SLHQVTILmSDRGLPqNYRqqHG B Chromobacterium_violaceum PyTNMRDaNanWDFWTLlPE--aLHQVTIVmSDRGIPaSYRHMHG B Colwellia_psychrerythraea PRTNMRSaqnnWDFWTslPE--aLHQITIVmSDRGLPaTYRHMHG B Cupriavidus_metallidurans PRTgMRSaesnWDFWTglPE--aLHQVTIVmSDRGIPrTWRHMHG B Desulfotalea_psychrophila PRTNMRSaannWDYWSslPE--aLHQVTItmSDRGIPlSYRHMNG B Haemophilus_influenzae PRTNMRSatnnWDFWTLlPE--aLHQVTVVmSDRGIPaSYRHMHG B Neisseria_gonorrhoeae PRTNMRSatnnWDFWTLlPE--aLHQVTIVmSDRGIPaSYRHMHG B Neisseria_meningitidis PRTNMRSatnnWDFWTLlPE--aLHQVTIVmSDRGIPagYRHMHG B Nitrosomonas_europaea PRTNLRSarnnWDFWTLlPE--aLHQITIVmSDRGLPaTYRHMHG B Nitrosomonas_eutropha PRTNLRSarnnWDFWTLlPE--aLHQITIVmSDRGIPtTYRHMHG B Photorhabdus_luminescens PhTNLRNpaykWDFFShqPE--SLHQLTIdFSDRGVPkSFRHMHG B Pseudomonas_aeruginosa PRTNLRNatfkWDFFShlPE--SLHQLTIdFSDRGLPkSYRHIHG B Streptomyces_coelicolor PRTNLRNaennWDFWTnlPE--aLHQVTIVmSDRGIPaSYRHMHG B Vibrio_fischeri PRTNMRSaknnWDFWTslPE--aLHQVTIVmSDRGIPaTYRHMHG B Vibrio_parahaemolyticus PRTNMRSstnnWDFWTslPE--afHQVTIVmSDRGIPaSYRHMHG B Yersinia_pestis PRTNLRNpvykWDFFSqlPE--aLHQLTIdFSDRGLPkSYRHMHG =============================================================================== B MICROCOCCUS_LUTEUS PdSgLRDatMqWDFWTnnPE--SaHQVTyLmgpRGLPrTWReMNG B Thermobifida_fusca PdTgLRDnNMqWDFWTLnPE--TaHQVTyLmgDRGLPrTWRHMNG =============================================================================== B HELICOBACTER_PYLORI PQTNLpNhDMvWDFWSnvPE--SLyQVTwVmSDRGIPkSFRHMDG B Helicobacter_pylori-CAA94567 PQTNLpNhDMvWDFWSnvPE--SLyQVTwVmSDRGIPkSFRHMDG B Helicobacter_pylori-CATA PQTNLpNhDMvWDFWSnvPE--SLyQVTwVmSDRGIPkSFRHMDG B Helicobacter_pylori-CATA_HELPJ PQTNLpNpDMvWDFWSnvPE--SLyQVTwVmSDRGIPkSFRHMDG =============================================================================== B ENTEROCOCCUS_FAECALIS PRTHLKSpeavWDFWShsPE--SLHQVTILmSDRGIPlSFRHMHG B Bacillus_licheniformis PvTHLKNpDavWDFWSLsPE--SLHQVTILmSDRGIPaTYRHMHG B Bacillus_subtilis PKTHLKNptavWDFWSLsPE--SLHQVTILmSDRGIPaTlRHMHG B Oceanobacillus_iheyensis PQTHLKDkDMvWDFWSLsPE--SLHQVTyLhSDRGLPaTlRHMNG =============================================================================== Consensus PQTNLRNxnmxWDFfSlxPExxsLHQVtiVfSDRGIPxsYRNMNG 280 290 300 310 ----:----|----:----|----:----|----:----|----: Consensus FGSHTFkxINaegExxWvKFHFRTEQGVQNLsnEEAxKIxgeDpD =============================================================================== * S_CEREVISIAE YsgHTYKwsNknGDwhYVQvHiKTDQGIKNLTiEEAtKIaGsNPD * Candida_albicans YsgHTYKwsNkKGEwfYVQvHFiSDQGIKtLNNEEAgaLaGsNPD * Candida_dubliniensis YsgHTYKwsNkKGEwfYVQvHFiSDQGIKtLTNEEAgaLaGsNPD * Candida_glabrata YsgHTYKwsNkKGEwhYVQvHilTDQGIKNLTNDEAvEIaGKNPD * Candida_tropicalis YsgHTYKwsNkKGEwhYVQvHFiTDQGnKtLTNEEAgsLaGsNPD * Debaryomyces_hansenii YsgHTYKwsNkKGEwyYVQvHFiSDQGVKtLTNEEAgELaGsNPD * Eremothecium_gossypii YsgHTYKwsNkQGDwrYVQvHiKTDQGIKNLTaEEgaKLaGEDPD * Kluyveromyces_lactis YsgHTYKwsNkQGEwrYVQvHlKTDQGIKNLNNEEAtKLaGENPD =============================================================================== * BOVINE YGSHTFKlVNADGEavYcKFHYKTDQGIKNLSvEDAaRLahEDPD * HUMAN YGSHTFKlVNAnGEavYcKFHYKTDQGIKNLSvEDAaRLsqEDPD * Anopheles_gambiae YGSHTYKlVNADGKpvYcKFHFKTDQGIKNLdparAnELtatDPD * Apis_mellifera YGSHTFslVNAKdEivYcKFHYKTDQGIKNLpvDKAgELsasNPD * Ascaris_lumbricoides FGSHTFKlVNkDGnavYcKFHiKTaQGIRNLppDvAiKLaGEDPD * Bombyx_mandarina YGSHTFKlVNsQGvgyWVKFHYKTnQGIKNLSvDKAgELastDPD * C_elegans YGSHTFKmVNkDGKaiYVKFHFKptQGVKNLTvEKAgQLassDPD * Canis_lupus YGSHTFKlVNAaGEavYcKFHYKTDQGIKNLSvEDAaRLshEDPD * Cavia_porcellus YGSHTFKlVNgsGEavYcKFHYKTDQGIKNLSvEDAaRLsqEDPD * Danio_rerio YGSHTFKlVNAQGQpvYcKFHYKTnQGIKNIpvEEAdRLaatDPD * D_melanogaster YGSHTFKlINAKGEpiYaKFHFKTDQGIKNLdvKtAdQLastDPD * D_pseudoobscura YGSHTFKlVNAKGEpiYaKFHmKTDQGIKNLdvKaAdELassDPD * Chicken YGSHTFKlVNAsGgavYcKFHvKTDQGIKNLSvEEAaRLastDPD * Litopenaeus_vannamei YGSrTsKlVNeKGEavYcKFHYKTDQGIKcLSSKKAdELaGsDPD * Pongo_pygmaeus YGSHTFKlVNAnGEavYcKFHYKTDQGIKNLSvEDAaRLsqEDPD * Rat YGSHTFKlVNAnGEavYcKFHYKTDQGIKNLpvEEAgRLaqEDPD * Pig YGSHTFKlVNeKGEavYcKFHYKTDQGIKNLSvEDAaRLpqEDPD * X_laevis YGSHTFKlVNAKdEavYcKFHYKTDQcIQNLTvDEAnRLaasDPD * X_tropicalis YGSHTFKlVNAKdEavYcKFHYKTDQGIRNLTvEEAnRLsasDPD * Mouse-CATA YGSHTFKlVNADGEavYcKFHYKTDQGIKNLpvgEAgRLaqEDPD * Mouse-Q3TXQ6 YGSHTFKlVNADGEavYcKFHYKTDQGIKNLpvgEAgRLaqEDPD =============================================================================== B PROTEUS_MIRABILIS FGSHTYsfINkDnErfWVKFHFRcQQGIKNLmDDEAeaLvGKDrE B 1H6NA_Proteus_mirabilis YGSHTYsfINkDnErfWVKFHFRcQQGIKNLmDDEAeaLvGKDrE B 1H7KA_Proteus_mirabilis FGSHTYsfINkDnErfWVKFHYRcQQGIKNLmDDEAeaLvGKDrE B Acinetobacter_calcoaceticus FsSHTYsfINsvnErfWVKFHFRTQQGIKNLTDaEAgELvGhDrE B Actinobacillus_pleuropneumoniae YGSHTYslINAnnErfWVKFHFRTEQGIKNLTNEEAaaIianDrE B Actinobacillus_succinogenes FGSHTYsmINAhnErfWVKFHFRTQQGIKNLTNEEAaaIianDrE B Bordetella_pertussis FGSHTYsfVNdaGErfYVKFHFKSQQGIacyTDgEAaELvGrDrE B Chromobacterium_violaceum FGSHTFslINAKGErhWVKFHFhTQQGIRNLSDaEAeKLvGQDrE B Colwellia_psychrerythraea FGSHTFsmINADnErvWVKFHFeSnQGIQNLTDQEAevViGQNrE B Cupriavidus_metallidurans FGSHTYsfINAnmErfWVKFHFvTQQGIQNLTDEEAaEItGQDrE B Desulfotalea_psychrophila YGSHTYslLNennErfWVKFHFKTQQGIKtLSDEEAeKLvGrDrE B Haemophilus_influenzae FGSHTYsfwNeaGErfWVKFHFRTQQGIKNLTDaEAaEIianDrE B Neisseria_gonorrhoeae FGSHTYsfwNeaGErfWVKFHFRSQQGIKNLTNEEAaKIiaDDrE B Neisseria_meningitidis FGSHTYsfwNeaGErfWVKFHFRTQQGIKNLTNEEAaKIiaDDrE B Nitrosomonas_europaea FGSHTFsfINArqEryWVKFHFRTQQGIKNLTDaEAeaLvGKDrE B Nitrosomonas_eutropha FGSHTFsfLNAQrEryWVKFHFRTQQGIKNLTDaEAetLiGEDrE B Photorhabdus_luminescens FGSHTFsfINADnErfWVKFHFRcQQGIKNLmDEEAeaLvGKDrE B Pseudomonas_aeruginosa FGSHTFsfINAnnErfWVKFHFKTQQGIENLTNaEAaEViaQDrE B Streptomyces_coelicolor FGSHTYslINAEGErfWVKFHhRTQQGIKNLTDaEAeaLvGKDrE B Vibrio_fischeri FGSHTFsfINsDnErfWVKFHFKSQQGIKNLSDaEAaQViGQDrE B Vibrio_parahaemolyticus FGSHTFsfINAEnEryWVKFHFKTQQGIKNIgDEEAqlLaGKDrE B Yersinia_pestis FGSHTFslINAnnErfWVKFHFRcQQGIENLmDDEAeKLiGsDrE =============================================================================== B MICROCOCCUS_LUTEUS YGSHTYlwVNAQGEkhWVKYHFiSQQGVhNLSNDEAtKIaGENaD B Thermobifida_fusca YGSHTYmwINAKGEkfWVKYHFKTDQGIENMTNEEAeRLaGvDaD =============================================================================== B HELICOBACTER_PYLORI FGSHTFslINAKGErfWVKFHFhTmQGVKHLTNEEAaEIrkhDPD B Helicobacter_pylori-CAA94567 FGSHTFslINAKGErfWVKFHFhTmQGVKHLTNEEAaEIrkhDPD B Helicobacter_pylori-CATA FGSHTFslINAKGErfWVKFHFhTmQGVKHLTNEEAaEVrkyDPD B Helicobacter_pylori-CATA_HELPJ FGSHTFslINAKGErfWVKFHFeTmQGVKHLTNEEAaEVrkyDPD =============================================================================== B ENTEROCOCCUS_FAECALIS FGSHTFKwVNAaGEvfFVKYHFKTnQGIKNLeSQlAeEIaGKNPD B Bacillus_licheniformis FGSHTFKwVNAEGEgvWIKYHFKTEQGIKNLTeEvgtKIaGENPD B Bacillus_subtilis FGSHTFKwtNAEGEgvWIKYHFKTEQGVKNLdvntAaKIaGENPD B Oceanobacillus_iheyensis YGSHTFKwVNAEGEafWVKYHFiSEQGIKNLdpalAdKIaGENPD =============================================================================== Consensus FGSHTFkxINaegExxWvKFHFRTEQGVQNLsnEEAxKIxgeDpD 320 330 340 350 360 ----|----:----|----:----|----:----|----:----| Consensus ynqQDLFdaIexGDYPsWslFIQVMteqEAExxpFNPFDVxxTKI =============================================================================== * S_CEREVISIAE YcQQDLFEAIQnGNYPSWTVYIQtMTERDAKklPFSvFDL--TKV * Candida_albicans YaQEDLFknIaaGNYPSWTaYIQtMTEaEAKeaeFSvFDL--TKV * Candida_dubliniensis YaQEDLFknIaaGNYPSWTaYIQtMTEaEAKeadFSvFDL--TKV * Candida_glabrata YcQQDLYEnIakGNYPSWTVYIQtMTEEQAKklPFSvFDL--TKV * Candida_tropicalis YaQEDLFknMlaGNYPSWTcYIQtMTEaQAKeadFSvFDL--TKV * Debaryomyces_hansenii FaQEDLFkeIakGNaPSWTcYIQtMTQEQAKkaPFSvFDL--TKV * Eremothecium_gossypii FcQQDLvqALErGEYPSWTVYIQtMTEEQAQklPFSvFDL--TKV * Kluyveromyces_lactis YcQKDLFEnIakGNYPSWTLYIQtMTEEEAEklPFSvFDL--TKV =============================================================================== * BOVINE YglRDLFNAIatGNYPSWTLYIQVMTfsEAEifPFNPFDL--TKV * HUMAN YgiRDLFNAIatGkYPSWTfYIQVMTfnQAEtfPFNPFDL--TKV * Anopheles_gambiae YSiRDLYNAIakkDFPSWTLkVQVMTfEQAEkvPYNPFDL--TKV * Apis_mellifera YaiQDLYDAIaknqYPTWTfYIQVMTptQAKsfkWNPFDL--TKV * Ascaris_lumbricoides YSiRDLYDsIEnGNYPvWrLmIQVMTfEEAanyrFNPFDI--TKV * Bombyx_mandarina YSiRDLYNsIakGDYPSWTfYIQVMTmaQAEsckFNPFDL--TKI * C_elegans YSiRDLFNAIEkGDFPvWkMFIQVMTfEQAEkweFNPFDV--TKV * Canis_lupus YglRDLFNAIatGNYPSWTfYIQVMTfsQAEtfPFNPFDL--TKI * Cavia_porcellus YglRDLFNAIatGNYPSWTLYIQVMTfQQAQsfPFNPFDL--TKI * Danio_rerio YSiRDLYNAIanGNFPSWTfYIQVMTfEQAEnwkWNPFDL--TKV * D_melanogaster YSiRDLYNrIKtckFPSWTMYIQVMTyEQAKkfkYNPFDV--TKV * D_pseudoobscura YSiRDLYNrIKtckFPSWTMYIQVMTfEEAKkfkYNPFDV--TKV * Chicken YgiRDLYNAIanGsYPSWSfYIQVMTfEEAErfPFNPFDLtkTKI * Litopenaeus_vannamei YatRDLYNAIssGDYPSYTMcIQVMTfEEAEkwkFNPFDL--TKV * Pongo_pygmaeus YgiRDLFNAIatekYPSWTfYIQVMTfnQAEtfPFNPFDL--TKV * Rat YglRDLFNAIasGNYPSWTfYIQVMTfKEAEtfPFNPFDL--TKV * Pig YgiRDLFNAIatGNYPSWTfYIQVMTfQEAEafPFNPFDL--TKV * X_laevis YgihDLYEAIttGNYPSWSfYIQVMTfEQAErfkFNPFDL--TKI * X_tropicalis YgihDLYEsIaaGNYPSWSfYIQVMTfQQAEkfkFNPFDL--TKI * Mouse-CATA YglRDLFNAIanGNYPSWTfYIQVMTfKEAEtfPFNPFDL--TKV * Mouse-Q3TXQ6 YglRDLFNAIanGNYPSWTfYIQVMTfKEAEtfPFNPFDL--TKV =============================================================================== B PROTEUS_MIRABILIS sSQRDLFEAIErGDYPrWkLqIQIMpEKEAstvPYNPFDL--TKV B 1H6NA_Proteus_mirabilis sSQRDLFEAIErGDYPrWkLqIQIMpEKEAstvPYNPFDL--TKV B 1H7KA_Proteus_mirabilis sSQRDLFEAIErGDYPrWkLqIQIMpEKEAstvPYNPFDL--TKV B Acinetobacter_calcoaceticus sHQRDLFDAIErkDFPkWTLYVQVMpEQDAEkvPYHPFDL--TKV B Actinobacillus_pleuropneumoniae sHQRDLYEsIEkGDFPkWkLYIQVMpEaEAEqvdFHPFDL--TKI B Actinobacillus_succinogenes sHQRDLYEsIEnGDFPrWTLYIQVMpEtDAEnvPYHPFDL--TKV B Bordetella_pertussis saQRDLFqnIEqGqFPrWTLkVQVMpEaEAatyhiNPFDL--TKV B Chromobacterium_violaceum saQRDLlEcIDrGDFPrWTLYIQVMTEaQADacPFNPFDL--TKV B Colwellia_psychrerythraea sHhaDLYDsLEsGDFPSWTLkIQVMTEEQAEksPYNPFDL--TKV B Cupriavidus_metallidurans YHQRDLFEsIErGDFPrWkLcVQIMpEaEAskvPYHPFDL--TKI B Desulfotalea_psychrophila sHQRDLlEAIDnhEFPSWkMqIQVVpEKEAanfPFNPFDL--TKV B Haemophilus_influenzae sHQRDLYEAIErGDFPkWTLFVQIMpEaDAEkvPYHPFDL--TKV B Neisseria_gonorrhoeae sHQRDLYEAIErGEFPkWTMYIQVMpEaDAEkvPYHPFDL--TKV B Neisseria_meningitidis sHQRDLYEAIErGEFPkWTMYIQVMpEaDAEkvPYHPFDL--TKV B Nitrosomonas_europaea sHQRDLYEsIEnGEFPrWTLFVQIMpEsDAaslPYNPFDL--TKV B Nitrosomonas_eutropha sHQRDLYEsIErGEFPrWTLFVQIMpEsDvadlsYNPFDL--TKV B Photorhabdus_luminescens sSQRDLFaAIEqGDYPrWkLkVQIMpEKEAnllPYNPFDL--TKV B Pseudomonas_aeruginosa sSQRDLYEsIEkGDFPrWkMYVQIMpEKEAatyrYNPFDL--TKV B Streptomyces_coelicolor sHQRDLFDAIEdGDFPkWkLFIQVMpEaDAEnyrFHPFDL--TKV B Vibrio_fischeri sHQRDLlEsIDnqDFPkWTLkVQIMpEaDAatvPYNPFDL--TKV B Vibrio_parahaemolyticus sHhRDLYEsIErqDFPkWkMYVQIMpElEADevnFNPFDL--TRV B Yersinia_pestis sSQRDLYEAIErGDFPrWkLqIQVMpEhEAsqtPYNPFDL--TKV =============================================================================== B MICROCOCCUS_LUTEUS FHRQDLFEsIakGDhPkWdLYIQaIpyEEgKtyrFNPFDL--TKt B Thermobifida_fusca FHRRDLvEAIErGDYPSWTLYVQVMpyEDAKtyrFNPFDL--TKV =============================================================================== B HELICOBACTER_PYLORI sNQRDLFNAIarGDYPkWkLsIQVMpEEDAKkyrFHPFDV--TKI B Helicobacter_pylori-CAA94567 sNQRDLFDAIarGDYPkWkLsIQVMpEEDAKkyrFHPFDV--TKI B Helicobacter_pylori-CATA sNQRDLFNAIarGDFPkWkLsIQVMpEEDAKkyrFHPFDV--TKI B Helicobacter_pylori-CATA_HELPJ sNQRDLFDAIagGDFPkWkMsIQVMpEEDAKkyrFHPFDV--TKI =============================================================================== B ENTEROCOCCUS_FAECALIS FHiEDLhNAIEnqEFPSWTLsVQIIpyaDAltmketlFDV--TKt B Bacillus_licheniformis YHtQDLYEAIEkGDFPaWkLYVQIMplEDADtyrFDPFDV--TKV B Bacillus_subtilis YHtEDLFNAIEnGDYPaWkLYVQIMplEDAntyrFDPFDV--TKV B Oceanobacillus_iheyensis YHtEDLFNAIEeGDhPaWkLYVQIMpyEDAKtykWDPFDV--TKI =============================================================================== Consensus ynqQDLFdaIexGDYPsWslFIQVMteqEAExxpFNPFDVxxTKI 370 380 390 400 ----:----|----:----|----:----|----:----|----: Consensus WphqEYPLMxVGklxLNKNPeNYFAEVEQxAFsPxNIVPGIexSP =============================================================================== * S_CEREVISIAE WPqgQFPLrrVGKIvLNENPlNFFAQVEQaAFaPsttVPyqEaSa * Candida_albicans WPHRKYPMrrfGKftLNENPENYFAEVEQaAFSPaHtVPyMEpSa * Candida_dubliniensis WPHKKYPLrrfGKftLNENPKNYFAEVEQaAFSPaHtVPyMEpSa * Candida_glabrata WPHKDFPLrrVGKMvMNENPlNYFAsIEQaAFSPaNtVPyqEpSa * Candida_tropicalis WPHgKYPLrrfGKftLNENPKNYFAEVEQaAFSPaHtVPyMEpSa * Debaryomyces_hansenii WPHKDYPMrrfGKLvLNENPKNYFAEIEQaAFaPaHtVPyMEaSa * Eremothecium_gossypii WPHKDFPLrrVGRLvLNEvPtNFFAQIEQaAFSPattVPyqEpSa * Kluyveromyces_lactis WPHKQFPLrrVGKMvLNENPENYFAQVEQaAFSPsHtVPyqEaSa =============================================================================== * BOVINE WPHgDYPLIpVGKLvLNRNPvNYFAEVEQlAFdPsNMpPGIEpSP * HUMAN WPHKDYPLIpVGKLvLNRNPvNYFAEVEQiAFdPsNMpPGIEaSP * Anopheles_gambiae WPqnEFPLIpVGRMvLDRNPsNYFAEVEQaAFaPsHLVPGIEpSP * Apis_mellifera WPHdEYPLIpVGKLvLNRNPENYFADIEQiAFdPaHMVPGIgaSP * Ascaris_lumbricoides WsHKEFPLIlVGKIvLNKNPtNYFAEVEQiAFaPsHVVPGIEfSP * Bombyx_mandarina WPHaEYPLIpVGKLvLDRNPKNYFAEVEQiAFSPsNLVPGIEpSP * C_elegans WPHgDYPLIeVGKMvLNRNPrNYFAEVEQsAFcPaHIVPGIEfSP * Canis_lupus WPHQDYPLIpVGKLvLNRNPvNYFAEVEQmAFdPsNMpPGIEpSP * Cavia_porcellus WPHKDYPLIpVGKLvLNRNPvNYFAEVEQiAFdPsNMpPGIEpSP * Danio_rerio WsHKEFPLIpVGRfvLNRNPvNYFAEVEQlAFdPsNMpPGIEpSP * D_melanogaster WsqKEYPLIpVGKMvLDRNPKNYFAEVEQiAFSPaHLVPGVEpSP * D_pseudoobscura WsHKEFPLIpVGKLvLDRNPKNYFAEVEQiAFSPaHLVPGIEpSP * Chicken WPHgDYPLIpVGKIvLNRNPvNYFtEVEQmAYdPsNMpPGIEpSP * Litopenaeus_vannamei WPHgEFPLIpVGRLtfDRNPKNYFAEVEQiAFSsaNMVPGIEaSP * Pongo_pygmaeus WPHKDYPLIpVGKLvLNRNPvNYFAEVEQiAFdPsNMpPGIEaSP * Rat WPHKDYPLIpVGKLvLNRNPaNYFAEVEQmAFdPsNMpPGIEpSP * Pig WPHsEYPLIpVGKLvLNRNPvNYFAEVEQmAFdPsNMpPGIEpSP * X_laevis WPHgDYPLIpVGKLvLNRNPtNYFAEVEQlAFdPsNMpPGIEpSP * X_tropicalis WPHgDYPLIpVGKLvLNRNPtNYFAEVEQlAFdPsNMpPGIEpSP * Mouse-CATA WPHKDYPLIpVGKLvLNKNPvNYFAEVEQmAFdPsNMpPGIEpSP * Mouse-Q3TXQ6 WPHKDYPLIpVGKLvLNKNPvNYFAEVEQmAFdPsNMpPGIEpSP =============================================================================== B PROTEUS_MIRABILIS WPHaDYPLMdVGyfeLNRNPDNYFsDVEQaAFSPaNIVPGIsfSP B 1H6NA_Proteus_mirabilis WPHaDYPLMdVGyfeLNRNPDNYFsDVEQaAFSPaNIVPGIsfSP B 1H7KA_Proteus_mirabilis WPHaDYPLMdVGyfeLNRNPDNYFsDVEQaAFSPaNIVPGIsfSP B Acinetobacter_calcoaceticus WPHgDYPLIeVGEfeLNRNPENFFlDVEQsAFaPsNLVPGIsaSP B Actinobacillus_pleuropneumoniae WskKDYPLIeVGvMeLNRNPaNFFADVEQsAFaPsNLVPGIsvSP B Actinobacillus_succinogenes WPkKDYPLIeVGvMeLNRNPaNFFADVEQsAFaPsNLVPGIsvSP B Bordetella_pertussis WPHaDYPLIeVGvLeLNKNPENYFAEVEQaAFTPaNVVPGIgfSP B Chromobacterium_violaceum WsHKDYPLIeVGvLeLNRNPQNYFADVEQaAFNPaNVVPGIsfSP B Colwellia_psychrerythraea WPHKDYPLIeVGvMeLNRNPENFFAEVEQsAFNPaSIVPGIsfSP B Cupriavidus_metallidurans WPkKDYPLIeVGvLeLNRNPDNFFAEVEQasFaPstIVPGVgfSP B Desulfotalea_psychrophila WPHdDYPLIdVGiMeLNKNPENYFAEVEQaAFNPaNIVPGIgfSP B Haemophilus_influenzae WskKDYPLIeVGEfeLNRNPENFFADVEQsAFaPsNLVPGIgaSP B Neisseria_gonorrhoeae WPkKDYPLIeVGEfeLNRNPENFFADVEQsAFaPsNLVPGIgaSP B Neisseria_meningitidis WPkKDYPLIeVGEfeLNRNPENFFADVEQsAFaPsNLVPGVgaSP B Nitrosomonas_europaea WPHKDYPLIeVGvMeLNRNPENYFAEVEQaAFNPaSVVPGIsfSP B Nitrosomonas_eutropha WPHKDYPLIeVGvMeLNRNPENYFAEVEQaAFNPaNVIPGIsfSP B Photorhabdus_luminescens WPHgDYPMIdVGyfeLNRNPDNYFsDVEQaAFNPaNVVPGIsfSP B Pseudomonas_aeruginosa WPHgDYPLIeVGffeLNRNPDNYFAEVEQaAFTPaNVVPGIgfSP B Streptomyces_coelicolor WskKDYPLIeVGEweLNRNPDNYFADVEQaAFSPaNVVPGIsfSP B Vibrio_fischeri WPHKDYPLIeVGEfeLNRNPQNFFAEVEQsAFNPaNVVPGIsfSP B Vibrio_parahaemolyticus WsqKDYPLIpVGEfeLNRNPENFYAEVEQsAFNPaaIVPGIgfSP B Yersinia_pestis WPHgDYPLIdVGyfeLNRNPENYFAEVEQssFNPaNVVPGIsfSP =============================================================================== B MICROCOCCUS_LUTEUS isqKDYPrIkVGtLtLNRNPENhFAQIEsaAFSPsNtVPGIglSP B Thermobifida_fusca WPHsDYPLIkVGKMtLNRNPENFFAEIEQaAFaPsNLVPGIgvSP =============================================================================== B HELICOBACTER_PYLORI WytQDYPLMeVGiVeLNKNPENYFAEVEQaAFTPaNVVPGIgySP B Helicobacter_pylori-CAA94567 WytQDYPLMeVGiVeLNKNPENYFAEVEQaAFTPaNVVPGIgySP B Helicobacter_pylori-CATA WylQDYPLMeVGiVeLNKNPENYFAEVEQaAFSPaNVVPGIgySP B Helicobacter_pylori-CATA_HELPJ WylQDYPLMeVGiVeLNKNPENYFAEVEQaAFTPaNVVPGIgySP =============================================================================== B ENTEROCOCCUS_FAECALIS vsqKEYPLIeVGtMtLNRNPENYFAEVEQvtFSPgNfVPGIEaSP B Bacillus_licheniformis WsqKDYPLIeVGRMvLNRNPENYFAEVEQatFSPgtLVPGIEpSP B Bacillus_subtilis WsqKDYPLIeVGRMvLDRNPENYFAEVEQatFSPgtLVPGIDvSP B Oceanobacillus_iheyensis WskKDYPrIeVGRMvLDRNPENYFAEVEQaAFSPgqfVPGIEaSP =============================================================================== Consensus WphqEYPLMxVGklxLNKNPeNYFAEVEQxAFsPxNIVPGIexSP 410 420 430 440 450 ----|----:----|----:----|----:----|----:----| Consensus DRMLQgRLFsYxDahRxyRLGxNyxQIPVNxPxxxxxxxinNxxx =============================================================================== * S_CEREVISIAE DpVLQaRLFSYaDAHR-YRLGpNFhQIPVNcPyas-k--ffNpai * Candida_albicans DpVLQsRLFSYaDtHRphRLGtNYtQIPVNcPvtg-a--VfNphs * Candida_dubliniensis DpVLQsRLFSYaDtHR-hRLGtNYtQIPVNcPvtg-a--VfNphm * Candida_glabrata DpVLQsRLFaYaDAHR-YRLGaNFhQIPVNcPyas-k--ffNpvi * Candida_tropicalis DpVLQsRLFSYsDtHR-hRLGtNYtQIPVNcPvtg-a--VfNphm * Debaryomyces_hansenii DpVLQsRLFSYaDtHR-hRLGtNYtQIPVNcPitg-r--VfNphm * Eremothecium_gossypii DpVLQaRLFSYaDAHR-YRIGpNYhQVPVNcPyas-k--ffNpai * Kluyveromyces_lactis DpVLQaRLFSYpDAHR-YRLGpNYsQIPVNcPyas-k--VfNpai =============================================================================== * BOVINE DKMLQGRLFaYpDtHR-hRLGpNYlQIPVNcPyra-r--VaNy-q * HUMAN DKMLQGRLFaYpDtHR-hRLGpNYlhIPVNcPyra-r--VaNy-q * Anopheles_gambiae DKMLQaRLFaYaDtHR-hRVGaNYlmLPVNcPyrv-a--trNf-q * Apis_mellifera DKMLQGRMFTYgDAHR-hRLGpNnlQLPVNcPfkeis--ViNy-q * Ascaris_lumbricoides DKMLQGRLFaYpDtqf-hRLGpNYvQLPINcPyrs-r--aHNt-q * Bombyx_mandarina DKMLQGRLFaYsDtHR-hRLGaNYlQIPVNcPykv-a--VSNy-q * C_elegans DKMLQGRIFSYtDtHf-hRLGpNYiQLPVNcPyrs-r--aHNt-q * Canis_lupus DKMLQGRLFaYpDtHR-hRLGpNYlQIPVNcPfra-r--VaNy-q * Cavia_porcellus DKMLQGRLFaYpDtHR-hRLGpNYlQIPVNcPyrt-r--VaNy-q * Danio_rerio DKMLQGRLFSYpDtHR-hRLGaNYlQLPVNcPyrt-r--VaNy-q * D_melanogaster DKMLhGRLFSYsDtHR-hRLGpNYlQIPVNcPykv-k--IeNf-q * D_pseudoobscura DKMLQGRLFSYsDtHR-hRLGpNYlQIPVNcPyrv-k--VNNf-q * Chicken DKMLQGRLFaYpDtHR-hRLGpNYlQIPVNcPyra-r--VaNy-q * Litopenaeus_vannamei DKMLQGRLFSYnDtHR-hRLGaNYtQIPVNcPyra-r--trNy-q * Pongo_pygmaeus DKMLQGRLFaYpDtHR-hRLGpNYlhIPVNcPyra-r--VaNy-q * Rat DKMLQGRLFaYpDtHR-hRLGpNYlQIPVNcPyra-r--VaNy-q * Pig DKMLQGRLFgYpDtHR-hRLGaNYlQIPVNcPfra-r--VaNy-q * X_laevis DKMLQGRLFSYpDtHR-hRLGpNYlQLPVNcPyrt-r--VaNy-q * X_tropicalis DKMLQGRLFSYpDtHR-hRLGpNYlQLPVNcPyrt-r--VaNy-q * Mouse-CATA DKMLQGRLFaYpDtHR-hRLGpNYlQIPVNcPyra-r--VaNy-q * Mouse-Q3TXQ6 DKMLQGRLFaYpDtHR-hRLGpNYlQIPVNcPyra-r--VaNy-q =============================================================================== B PROTEUS_MIRABILIS DKMLQGRLFSYgDAHR-YRLGvNhhQIPVNaPk-c-p--fHN-yh B 1H6NA_Proteus_mirabilis DKMLQGRLFSYgDAHR-YRLGvNhhQIPVNaPk-c-p--fHN-yh B 1H7KA_Proteus_mirabilis DKMLQGRLFSYgDAHR-YRLGvNhhQIPVNaPk-c-p--fHN-yh B Acinetobacter_calcoaceticus DRMLQaRLFNYaDAqR-YRLGvNYqQIPVNaar-c-p--VHS-nh B Actinobacillus_pleuropneumoniae DRMLQaRLFNYaDAqR-YRLGvNhhQIPVNaPr-c-p--VHS-na B Actinobacillus_succinogenes DRMLQaRLFNYaDAqR-YRLGvNFnQIPVNaPr-c-p--VHS-na B Bordetella_pertussis DKMLQGRLFSYgDtHR-YRLGiNhhQIPVNaPr-c-p--fHS-fh B Chromobacterium_violaceum DRMLQGRLFaYgDAeR-YRLGvNhhlIPVNaPr-c-p--fHNsyh B Colwellia_psychrerythraea DKMLQGRLFSYgDAqR-YRLGvNhqQIPVNaPr-c-p--VHS-yh B Cupriavidus_metallidurans DKMLQGRLFSYgDAaR-YRVGvNhhQIPVNsPk-a-akyVNS-yh B Desulfotalea_psychrophila DKMLQGRLFSYgDAqR-YRLGvNhhlIPVNrar-c-p--fHS-fh B Haemophilus_influenzae DRMLQaRLFNYaDAqR-YRLGvNYrQIPVNrPr-c-p--VHS-nq B Neisseria_gonorrhoeae DKMLQaRLFNYaDAqR-YRLGvNFrQIPVNrPr-c-p--VHS-nq B Neisseria_meningitidis DKMLQaRLFNYaDAqR-YRLGvNFrQIPVNrPr-c-p--VHS-nq B Nitrosomonas_europaea DKMLQGRLFSYgDAqR-YRLGvNhyQIPVNaPr-c-p--fHH-yh B Nitrosomonas_eutropha DKMLQGRLFSYgDAqR-YRLGvNhhQIPVNaPr-c-p--fHN-yh B Photorhabdus_luminescens DKMLQGRLFSYgDAqR-YRLGvNhhQIPVNtPr-c-p--fHN-yh B Pseudomonas_aeruginosa DKMLQGRLFSYgDAHR-YRLGvNhhQIPVNaar-c-p--hqv-yh B Streptomyces_coelicolor DRMLQGRLFSYgDAqR-YRLGvNhhQIPVNaPk-n-p--VNS-yh B Vibrio_fischeri DKMLQGRLFaYgDAqR-YRLGvNhqhIPVNaPr-c-p--VHS-yh B Vibrio_parahaemolyticus DKMLQGRLFaYgDAqR-YRLGvNhhQIPVNaPr-c-p--VHS-yh B Yersinia_pestis DRMLQGRLFSYgDAaR-YRLGvNhhQIPVNsak-c-p--fHN-yh =============================================================================== B MICROCOCCUS_LUTEUS DRMLlGRaFaYhDAql-YRVGaHvnQLPVNrPk-n-a--VHNy-a B Thermobifida_fusca DKMLlGRVFaYaDAHR-aRIGtNYfQLPVNkPr-v-k--VNSy-t =============================================================================== B HELICOBACTER_PYLORI DRMLQGRLFSYgDtHR-YRLGvNYpQIPVNkPr-c-p--fHSs-s B Helicobacter_pylori-CAA94567 DRMLQGRLFSYgDtHR-YRLGvNYpQIPVNkPr-c-p--fHSs-s B Helicobacter_pylori-CATA DRMLQGRLFSYgDtHR-YRLGvNYpQIPVNkPr-c-p--fHSs-s B Helicobacter_pylori-CATA_HELPJ DRMLQGRLFSYgDtHR-YRLGvNYpQIPVNrPr-c-p--fHSs-s =============================================================================== B ENTEROCOCCUS_FAECALIS DKLLQGRLFaYgDAHR-hRVGaNshQLPINqak-a-p--VNNy-q B Bacillus_licheniformis DKMLQGRLFaYaDAHR-YRVGaNhnsLPINrPk-a-e--VHNy-q B Bacillus_subtilis DKMLQGRLFaYhDAHR-YRVGaNhqaLPINrar-n-k--VNNy-q B Oceanobacillus_iheyensis DKMLQGRLFgYsDAHR-YRLGaNhhsIPVNrPk-n-e--VNNy-q =============================================================================== Consensus DRMLQgRLFsYxDahRxyRLGxNyxQIPVNxPxxxxxxxinNxxx 460 470 480 490 ----:----|----:----|----:----|----:----|----: Consensus RDGxMxMxnxhxgxxxxpnYxpsSfxxxxQexxpxxxxxxlxxxx =============================================================================== * S_CEREVISIAE RDGpMnV-NgNfGs--ePtYlaN-dk-syty-iqqdrpiqqhqev * Candida_albicans RDGaMtV-NgNlGs--hPNYlaS-dk-pvEf--kqfssfqedqev * Candida_dubliniensis RDGaMtV-NgNlGs--hPNYlaS-dk-pvEf-kq--fslqedqev * Candida_glabrata RDGpMnV-DgNfGn--ePNYyaS-nk-qyQi-pnqdrpiqqhqev * Candida_tropicalis RDGaMnV-NgNlGs--hPNYlaS-dk-piEf-kq--fslqedqev * Debaryomyces_hansenii RDGgMnV-NgNlGs--hPNYlaT-sk-pvEf---knfsiqeeqev * Eremothecium_gossypii RDGpMnV-DgNlGs--ePNYlaT-nn-nyRf-lgadrpiqqhqet * Kluyveromyces_lactis RDGpMnV-NgNlGk--ePNYlsT-sk-kyQf-iqqskpiqqhqev =============================================================================== * BOVINE RDGpMcM-mdNqGg--aPNYyPNSFs-apEh-qP--sa--Lehrt * HUMAN RDGpMcM-qdNqGg--aPNYyPNSFg-apEQ-qP--sa--Lehsi * Anopheles_gambiae RDGpMnc-tdNqGg--aPNYfPNSFs-gpQt-cP--rahkLqntp * Apis_mellifera RDGqatI--nNqng--aPNYfPNSFg-gpRE-cP--av--appty * Ascaris_lumbricoides RDGcfaL-DyNqGg--mPtYhPNSFn-gaiE-rt--dv--kesaw * Bombyx_mandarina RDGpqaI-H-Nqdd--cPNYfPNSFs-gpQE-cP--raqrLqpry * C_elegans RDGaM-a-ydNqqh--aPNFfPNSFn-ygKt-rP--dv--kdttf * Canis_lupus RDGpMcM-ldNqGg--aPNYyPNSFs-apEQ-qr--cv--Lehss * Cavia_porcellus RDGpMcV-tdNqGg--aPNYyPNSFs-apvE-qr--qa--Lehts * Danio_rerio RDGpMcM-HdNqGg--aPNYyPNSFs-apdv-qP--rf--Leskc * D_melanogaster RDGaMnV-tdNqdg--aPNYfPNSFn-gpQE-cPrara--Lsscc * D_pseudoobscura RDGlMnV-tdNqdg--aPNYfPNSFn-gpQE-cPrara--Lstcc * Chicken RDGpMcV-SdNqGg--aPNYyPNSFt-gpED-qP--vl--kesrm * Litopenaeus_vannamei RDGpMcV-DgNqes--aPNYfPNSFs-gpQD-cr--kh--tapkf * Pongo_pygmaeus RDGpMcM-qdNqGg--aPNYyPNSFg-apEQ-qP--sa--Lehst * Rat RDGpMcM-HdNqGg--aPNYyPNSFs-apEQ-qg--sa--Lehhs * Pig RDGpMcf-qdNqGg--aPNYyPNSFs-apEQ-th--sa--Lehct * X_laevis RDrpMcf-tdNqGg--aPNYyPNSFc-apEn-qP--qv--rehrf * X_tropicalis RDGpMcf-tdNqGg--aPNYyPNSFc-apEn-qP--qv--rehrf * Mouse-CATA RDGpMcM-HdNqGg--aPNYyPNSFs-apEQ-qr--sa--Lehsv * Mouse-Q3TXQ6 RDGpMcM-HdNqGg--aPNYyPNSFs-apEQ-qr--sa--Lehsv =============================================================================== B PROTEUS_MIRABILIS RDGaMrV-DgNsGn-g-itYePNSgg-vfQEq-PdfkeppLsieg B 1H6NA_Proteus_mirabilis RDGaMrV-DgNsGn-g-itYePNSgg-vfQEq-PdfkeppLsieg B 1H7KA_Proteus_mirabilis RDGaMrV-DgNsGn-g-itYePNSgg-vfQEq-PdfkeppLsieg B Acinetobacter_calcoaceticus RDGqgrI-DaNyGg-l-PHYePNSFg-qwQEq-PqykeppLking B Actinobacillus_pleuropneumoniae RDGqsrV-DgNyGs-t-lHYePNSFg-qwQEq-aqfaeppLking B Actinobacillus_succinogenes RDGqgrV-DgNyGs-t-iHYePNSFg-qwQEq-aqfaeppLking B Bordetella_pertussis RDGmgrV-DgNgGa-t-lNYePNSFg-ewREa-khaaeppLaldg B Chromobacterium_violaceum RDGaMrV-DsNaGa-t-igYePNSqg-kwQQq-PaydeppLalqg B Colwellia_psychrerythraea RDGaMrV-DgNhGs-t-igYePNTqg-ewQEq-PdfseppMelsg B Cupriavidus_metallidurans RDGtMrV-DgNrGa-a-igYePNTkg-ewaEq-PdfreppLtleg B Desulfotalea_psychrophila RDGaMrV-DgNyGg-t-rgYePNSYg-ewREq-PefkeppLtleg B Haemophilus_influenzae RDGqgrV-DgNyGs-l-PHYePNSFs-qwQQq-PdfaeppLring B Neisseria_gonorrhoeae RDGqgra-DgNyGs-l-PHYePNSFg-qwQQq-PdfaeppLking B Neisseria_meningitidis RDGqgra-DgNyGs-l-PHYePNSFg-qwQQq-PdfaeppLking B Nitrosomonas_europaea RDGaMrV-DgNqGs-t-lgYePNSYq-ewQQq-PeyaeppLtleg B Nitrosomonas_eutropha RDGtMrV-DgNhds-t-lgYePNSYq-ewQQq-PgyaeppLaleg B Photorhabdus_luminescens RDGaMrV-DgNsGn-t-vtYePNNag-lfQEq-PefkhpsLsleg B Pseudomonas_aeruginosa RDGgMrV-DgNnahqr-vtYePNSFn-qwQEq-PdfseppLsleg B Streptomyces_coelicolor RDGaMrV-DgNqGa-t-PgvePNSYg-rwQEq-Payrdpaqavga B Vibrio_fischeri RDGaMrV-DgNfGs-t-lgYePNNeg-qwaEq-PdfaepaLnldg B Vibrio_parahaemolyticus RDGaMrV-DgNfGs-t-lgYePNykq-ewaEq-PdyseppLrisg B Yersinia_pestis RDGaMrV-DgNsGn-g-atYePNSFg-lfQEq-PdfseppLtleg =============================================================================== B MICROCOCCUS_LUTEUS fEGqMwy--dHtGdr--stYvPNSng-dswsd-etgpvddgwead B Thermobifida_fusca fDGhMty--eHsGka--PvYaPNSYg-rpwsd-qtgpvedswead =============================================================================== B HELICOBACTER_PYLORI RDGyMqn--gyyGsl--qNYtPSSlp-gyKEd-ksardpkfnlah B Helicobacter_pylori-CAA94567 RDGyMqn--gyyGsl--qNYtPSSlp-gyKEd-ksardpkfnlah B Helicobacter_pylori-CATA RDGyMqn--gyyGsl--qNYtPSSlp-gyKEd-ksardpkfnlah B Helicobacter_pylori-CATA_HELPJ RDGyMqn--gyyGsl--qNYtPSSlp-gyKEd-ksardpkfnlah =============================================================================== B ENTEROCOCCUS_FAECALIS KDGnMrf-N-Ngnse--iNYePNSYtetpKEd-Ptakissfeveg B Bacillus_licheniformis RDGqMrf-DsNgGgs--vyYePNSF-ggpQEt-Penkttaypvsg B Bacillus_subtilis RDGqMrfgD-NgGgs--vyYePNSF-ggpKEs-Pedkqaaypvqg B Oceanobacillus_iheyensis RDGfMsV-DgNgGnk--PNYePNS-vngptEd-seakinpfeiyg =============================================================================== Consensus RDGxMxMxnxhxgxxxxpnYxpsSfxxxxQexxpxxxxxxlxxxx 500 510 520 530 540 ----|----:----|----:----|----:----|----:----| Consensus xxxxxxxxxfxxxxxdxdxxfsqxxxxyxxlxxeeqrkxlxxnix =============================================================================== * S_CEREVISIAE wngpaipyhWatspgDvDfvqaRnly-rvlgkqpgQQKnLayNIg * Candida_albicans wngaatpfhWkatpa-d-fkqaQelw-kvlkrypnQQEhLahNIa * Candida_dubliniensis wngaatpfhWkatpa-d-fkqaQelw-kvlkrypnQQEhLahNIa * Candida_glabrata wngpaqpfhWatspgDiDfvqaRdly-kvlgkqKDQQEhLayNIg * Candida_tropicalis whgaatpfhWkatpa-d-fkqSQelw-kvlkrypnQQEhLahNVa * Debaryomyces_hansenii wegaacpfhWkct--DkDysqataly-nvlakypnQQKnLahNVa * Eremothecium_gossypii wqgpaqpvhWatt-gDiDfaqataly-hvlgrtpgQQRnLahNVa * Kluyveromyces_lactis wsgpampvhWatspgDiDfvqaRdlynkvlskqpgQQKaLahNVa =============================================================================== * BOVINE -hfsgdvqrFn-sa-N-DdnvTQvrtfYlkVlnEEQRKrLceNIa * HUMAN -qysgevrrFn-ta-N-DdnvTQvrafYvnVlnEEQRKrLceNIa * Anopheles_gambiae lklsgdvnrYe-tg-D-EdnFSQatvfYrrVldDagRQrLinNIv * Apis_mellifera -fvsgdvgrYdvdp-k-EdnFgQvtlfWrnVldDKEKsrLvnNLv * Ascaris_lumbricoides -svsgdvdrFn-gd-D-EdnFSQprdlWlkVmdEtERarLvdNIa * Bombyx_mandarina -nvggdvdrYd-sgqt-EdnFSQatalYkqVfdDaaKQraiaNIv * C_elegans -patgdvdrYe-sg-D-DnnYdQprqfWekVldtgaRErMcqNfa * Canis_lupus -qcspdvqrFn-sa-N-EdnvTQvrtfYlkVlgEEERKrLceNIa * Cavia_porcellus -rcsgdvgrYn-st-D-DdnvTQvrafYtqVlnEEQRRrLceNIa * Danio_rerio -kvspdvarYn-sa-D-DdnvTQvrtfFtqVlnEaERErLcqNMa * D_melanogaster -pvtgdvyrYs-sg-DtEdnFgQvtdfWvhVldKcaKKrLvqNIa * D_pseudoobscura -pvtgdvyrYs-sg-DtEdnYgQvtdfWvhtldncaRKrLvaNIa * Chicken -svsgdvqrFs-sa-N-EdnvSQvrdfYlkVlkEDERQrLckNIa * Litopenaeus_vannamei -svsadvdrYn-sa-D-EdnFTQvgifYrqVlnEaERQrLveNIa * Pongo_pygmaeus -qcsgevqrFn-ta-s-DdnvTQvrafYvnVlnEEQRKrLceNIa * Rat -qcsadvkrFn-sa-N-EdnvTQvrtfYtkVlnEEERKrLceNIa * Pig -rysgdvqrFn-sa-N-EdnvTQvrtfYlnVlnEEERKrLceNIa * X_laevis -qvsadvarYn-ss-D-EdnvSQvrdfYvkVlsEEQRlrLceNIa * X_tropicalis -hvsadvarYn-sa-D-EdnvSQvrdfYvkVlsEEQRlrLceNIa * Mouse-CATA -qcavdvkrFn-sa-N-EdnvTQvrtfYtkVlnEEERKrLceNIa * Mouse-Q3TXQ6 -qcavdvkrFn-sa-N-EdnvTQvrtfYtkVlnEEERKrLceNIa =============================================================================== B PROTEUS_MIRABILIS -aadhwnh-r-e-d-E-D-yFSQpralYelLsdDEhQRmfariag B 1H6NA_Proteus_mirabilis -aadhwnh-r-e-d-E-D-yFSQpralYelLsdDEhQRmfariag B 1H7KA_Proteus_mirabilis -aadhwnh-r-e-d-E-D-yFSQpralYelLsdDEhQRmfariag B Acinetobacter_calcoaceticus -dadfwny-r-e-d-DnD-yFSQpralFelMtpEQQQalfdnter B Actinobacillus_pleuropneumoniae -daafwdy-r-q-d-DsD-yFSQpralFnlMteKEKQslfkntae B Actinobacillus_succinogenes -daahwdy-r-end-s-D-yFSQprtlFnlMteKERQslfnntad B Bordetella_pertussis qaadrwnh-r-v-d-E-D-yYSQpgalFrlMndDQKQQlfgnigr B Chromobacterium_violaceum -nayhydf-rad-d-D-D-yYSQpgalFrlMtpaQQQalfdntar B Colwellia_psychrerythraea -aaahwnh-r-e-d-E-D-yFSQpgdlFrlMdnsQQQalfdntar B Cupriavidus_metallidurans -tadhwnh-r-e-d-g-D-yFSQvgalFrlMsptQQQalfdntar B Desulfotalea_psychrophila -aadhwnh-r-e-dsD-D-yYSQpgnlFrlMtaEQKKvlfentar B Haemophilus_influenzae -daahwdy-rnd-d-N-D-yFSQpralFnlMnaEQKQslfnntaa B Neisseria_gonorrhoeae -daahwdyrq-d-d-D-D-yFSQpralFnlMndaQKQalfdntaa B Neisseria_meningitidis -daahwdy-rqd-d-D-D-yFSQpralFnlMndaQKQalfgntaa B Nitrosomonas_europaea -aaahwnh-r-v-d-E-D-yYiQpgnlFrlMnssQQQvlfdntar B Nitrosomonas_eutropha -saahwnh-r-e-d-g-D-yYTQpgnlFrlMspaQQQilfdntar B Photorhabdus_luminescens -dadhwnh-r-q-d-E-D-yFSQprklFmlInsKEhQRmfdrias B Pseudomonas_aeruginosa -aadhwnh-r-v-d-D-D-yYSQpaalFhlftdEQKQRlfaniae B Streptomyces_coelicolor -vadrfny-r-e-d-D-DnyFeQpgnlFrqMspEQQQvlfentar B Vibrio_fischeri -aaahwdh-r-e-d-E-D-yFSQpgdlFrlMtaEQQailfdntar B Vibrio_parahaemolyticus -hadhydh-r-v-d-E-D-yFSQagdlFrlMneEQRQalfdntar B Yersinia_pestis -aadhwnh-r-e-d-t-D-yFSQpralFnlLseEEhQRmftriag =============================================================================== B MICROCOCCUS_LUTEUS gtltreaqalradddDfgqagTlvrevFsdqerDDfvEtVagaL- B Thermobifida_fusca gelvrsayelhaeddDfsqagTlvrevFddaqrDrlvEtVadHLs =============================================================================== B HELICOBACTER_PYLORI iekefevwnWdyradDsDyytqpgdyyrslpadEKERlhdtiges B Helicobacter_pylori-CAA94567 iekefevwnWdyradDsDyytqpgdyyrslpadEKERlhdtiges B Helicobacter_pylori-CATA iekefevwnWdyradDsDyytqpgdyyrslpadEKERlhdtiges B Helicobacter_pylori-CATA_HELPJ iekefevwnWdyraeDsDyytqpgdyyrslpadEKERlydtiggs =============================================================================== B ENTEROCOCCUS_FAECALIS nvgnysyn-q-dhftqaNalYNllpseekenlinniaasLgqvkn B Bacillus_licheniformis sadstayd-hndhytqagdlYrllseeertrlvsnivgsMkqvtk B Bacillus_subtilis iadsvsyd-hydhytqagdlYrlmsedertrlvEnivnaMkpvek B Oceanobacillus_iheyensis qadsvtydsd-dhytqagdlYrlmsadekdrlvEafvghMtpvtk =============================================================================== Consensus xxxxxxxxxfxxxxxdxdxxfsqxxxxyxxlxxeeqrkxlxxnix 550 560 570 580 ----:----|----:----|----:----|----:----|----: Consensus xxlexxexxvqqqlxxxfxxxxxexxxxxqaxxxxxxxxxxxxxx =============================================================================== * S_CEREVISIAE ihVEgacpqIQQRVydmFarvdkgl--------s-ea-------- * Candida_albicans vhaagaDaaIQdRVfayFgkvsqDl--------a-da-------- * Candida_dubliniensis vhaagaDaaIQdRVfayFgkvsqDl--------a-na-------- * Candida_glabrata thVagaDpeIQQRVidmFsrvdegl--------g-an-------- * Candida_tropicalis vhasaaDapIQdKViayFakvspEl--------s-nl-------- * Debaryomyces_hansenii vhVsgaEthIQdKVfdmFakvhpEl--------s-an-------- * Eremothecium_gossypii ihVasaDppIQERVfqmFsrvdkgl--------g-ea-------- * Kluyveromyces_lactis vhVasacpeIQdRVfamFarvdrgl--------s-en-------- =============================================================================== * BOVINE ghLKdaQlfIQKKavknFsdvhpEygsriQAl--ldk-------- * HUMAN ghLKdaQifIQKKavknFtevhpDygshiQAl--ldk-------- * Anopheles_gambiae ghLKdaspfLQERavknFamvdaDfgrhlseg--lkl-------- * Apis_mellifera qnLsnasmfIvERavknFtqvdaDlglrlteg--lrn-------- * Ascaris_lumbricoides dsLKycKafIQERainnFtqvhqDfgnalRna--lqk-------- * Bombyx_mandarina dhLKdaaafIQERaikiFsqvhpElgnkvaAg--lap-------- * C_elegans gpLgechdfIiKgMidhFskvhpDfgarvKAl--iqk-------- * Canis_lupus ghLKdaQlfIQKKavknFsdvhpDygariQAl--ldk-------- * Cavia_porcellus ghLKdaQlfIQKKavknFmdvhpDygnriQtl--ldk-------- * Danio_rerio ghLKgaQlfIQKRMvqnlmavhsDygnrvQAl--ldk-------- * D_melanogaster ghLsnasqfLQERavknFtqvhaDfgrmltee--lnl-------- * D_pseudoobscura ghLnnasqfLQERavknFtqvhaDfgrmltea--lnl-------- * Chicken dhLKdaQlfIQKRavknFtdvhpDygariQAl--ldk-------- * Litopenaeus_vannamei ghMvgaQefIQdRaiknFtqadpEyganiRra--idk-------- * Pongo_pygmaeus ghLKdaQifIQKKavknFtevhpDygsriQAl--ldk-------- * Rat nhLKdaQlfIQRKavknFtdvhpDygarvQAl--ldq-------- * Pig ghLKdaQlfIQKKavknFsdvhpDygariQAl--ldk-------- * X_laevis ghLKdaQlfIQKRavknFtdvhpEygariQAl--ldk-------- * X_tropicalis ghLKdaQlfIQKRavknFtdvhpEygariQAl--ldk-------- * Mouse-CATA ghLKdaQlfIQKKavknFtdvhpDygariQAl--ldk-------- * Mouse-Q3TXQ6 ghLKdaQlfIQKKavknFtdvhpDygariQAl--ldk-------- =============================================================================== B PROTEUS_MIRABILIS elsQasKetqQRQIdlftkvhpeygagveKA--i------kv--- B 1H6NA_Proteus_mirabilis elsQasKetqQRQIdlftkvhpeygagveKA--i------kv--- B 1H7KA_Proteus_mirabilis elsQasKetqQRQIdlftkvhpeygagveKA--i------kv--- B Acinetobacter_calcoaceticus amgDalDfikyRhIrncYachpaygegvaKA--l------gl--t B Actinobacillus_pleuropneumoniae gmgDalDfikyRhIrncYfcdpaygegvaKA--l-gmtvada--- B Actinobacillus_succinogenes amgDalDfikyRhIrncYfcdpaygegvaKA--l------rmtvt B Bordetella_pertussis hmagvpEeiqRRQLehfrradpayaagvaKA--l------gl--- B Chromobacterium_violaceum amggvdEaikRRhIancakadpaygagvaKA--l------gl--- B Colwellia_psychrerythraea svggasidiqKRhIshclkadqaygagvaKA--l------gi--- B Cupriavidus_metallidurans sikgvsKhiqQthIkhctaadpaygagvaaA--i------em--- B Desulfotalea_psychrophila algDapraikmRhasncqkadraygegvamA--l------gl--- B Haemophilus_influenzae amgDapDfikyRhIrnchwcdaaygegvaKA--l-gltveda--- B Neisseria_gonorrhoeae amgDapDfikyRhIrncYrcdpaygegvaKA--l------gl--t B Neisseria_meningitidis amgDapDfikyRhIrncYrcdpaygegvaKAlgl------tv--- B Nitrosomonas_europaea sigEapreiqiRhItnclkadraygegvaRA--l------gi--- B Nitrosomonas_eutropha aigEasresqlRhIihclnadrayaegvaRA--l------ei--- B Photorhabdus_luminescens elsQahEdtqRRQVelfrkvhpeygagvenA--l------kk--- B Pseudomonas_aeruginosa dirDvpEqiqRRQIglflkvdpaygkgvadA--l------gl--- B Streptomyces_coelicolor aidgasaqtIERhIgnctqadpaygagvrKA--i------ea--- B Vibrio_fischeri nlngvpKeiqlRhLrhcYkadpaygegigKl--l------di--- B Vibrio_parahaemolyticus amdgvpDfikERhVthaYqadeaygkglelA--l------gl--- B Yersinia_pestis elsQvpEaiqRRQIalftqvdpaygagvkKA--l------gl--- =============================================================================== B MICROCOCCUS_LUTEUS kgVrqdvqarafEywknvdatigQriede-----vkr-------- B Thermobifida_fusca kgVvepvlsrafQywknidetigEriek-------ry-------- =============================================================================== B HELICOBACTER_PYLORI lahvthKeiVdKQLehfkkadpkyaegvkKA--l-ek-------- B Helicobacter_pylori-CAA94567 lahvthKeiVdKQLehfkkadpkyaegvkKA--l-ek-------- B Helicobacter_pylori-CATA lahvthKeiVdKQLehfkkadpkyaegvkKA--l-ek-------- B Helicobacter_pylori-CATA_HELPJ lahvthKeiVdKQLehfkkadpkyaegvkKA--l-ek-------- =============================================================================== B ENTEROCOCCUS_FAECALIS qeIiarQidLftRVnpeYgarvaQ----a----i-kq-------- B Bacillus_licheniformis deIKlrQiqhfyKadpeYgtrvaE----g----l-gl-------- B Bacillus_subtilis eeIKlrQiehfyKadpeYgkrvaEglglp----i-kk-------- B Oceanobacillus_iheyensis deIKlrQiehiyKadaeWgervaQ----g----l-gl-------- =============================================================================== Consensus xxlexxexxvqqqlxxxfxxxxxexxxxxqaxxxxxxxxxxxxxx 590 600 610 620 630 ----|----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx =============================================================================== * S_CEREVISIAE --i--k---kv--a--e--akh-a-s-e--l-ss--ns-----kf * Candida_albicans --i--k--------------ke-v-l-e--l-sp--rk------- * Candida_dubliniensis --i--k--------------ke-v-l-e--l-sp--rk------- * Candida_glabrata --i--r---ke--i--e---kn-a-s-a--p-ta--ki------- * Candida_tropicalis --i--k--------------ke-i-l-e--l-sp--rk------- * Debaryomyces_hansenii --i--k--------------ke-a-l-q--l-sp--rk------- * Eremothecium_gossypii --i--r---s------e--ata-l-s-q-----k--kp-----kl * Kluyveromyces_lactis --i--k---ke--a--l--sls-p-r-k--a-aa-lna-----kl =============================================================================== * BOVINE ---y--n--ee--k--p--kn------------------------ * HUMAN ---y--n--ae--k--p--kn-a-i-h-t-f-v-q---sg---sh * Anopheles_gambiae ------r--rt---------------------------------- * Apis_mellifera ---k--g--v------------l-i-n-r-y-g-k---ta----r * Ascaris_lumbricoides ---a--n--ea--m--q--kk-r-e-e-e-a-e-fn--ake--sv * Bombyx_mandarina ---y--k--ky--h--a--nl------------------------ * C_elegans ---------qa--r--s--hi------------------------ * Canis_lupus ---y--n--ae--k--p--kn-a-i-h-t-f-m-q---hg---sh * Cavia_porcellus ---y--n--ve--k--p--kn-a-i-h-t-f-v-q---dg---sh * Danio_rerio ---h--n--ae--g--k--kn-t-v-h-v-y-s-r---gga--sa * D_melanogaster ----------a--k--s--sk---------f-------------- * D_pseudoobscura ---a--k--ss--k--f---------------------------- * Chicken ---y--n--ae--ag-k--kd-v-i-r-t-y-t-q---at---sr * Litopenaeus_vannamei ---i--k--ms--q--a--ss-k-t-------------------- * Pongo_pygmaeus ---y--n--ae--k--p--kn-a-i-h-t-f-v-q---sg---sh * Rat ---y--n--sq--k--p--kn-a-i-h-t-y-v-q---ag---sh * Pig ---y--n--ae---------------------------------- * X_laevis ---y--n--aeg-a--k--kk-t-v-k-t-y-t-q---hs---sy * X_tropicalis ---y--n--aeg-a--k--kk-t-v-k-t-y-t-q---hs---ty * Mouse-CATA ---y--n--ae--k--p--kn-a-i-h-t-y-t-q---ag---sh * Mouse-Q3TXQ6 ---y--n--ae--k--p--kn-a-i-h-t-y-t-q---ag---sh =============================================================================== B PROTEUS_MIRABILIS ---l--e--gk--d--a--k------------------------- B 1H6NA_Proteus_mirabilis ---l--e-------------------------------------- B 1H7KA_Proteus_mirabilis ---l----------------------------------------- B Acinetobacter_calcoaceticus ---v--e--na--q--a--are-t-d-p-a-r-g-lps--fi--- B Actinobacillus_pleuropneumoniae ---m--e--ay--n--t--dpa-m-g-q-p-g-l-ikp--nf--- B Actinobacillus_succinogenes da-m--e--ay--n--t--dpa-l-g-q-p-g-l-ikp--df--- B Bordetella_pertussis ---k----------------------------------------- B Chromobacterium_violaceum ---s--v-------------------------------------- B Colwellia_psychrerythraea ---l--l--dt--i------------------------------- B Cupriavidus_metallidurans ---i--e--ak---------------------------------- B Desulfotalea_psychrophila ---p--v--se--l--e--e------------------------- B Haemophilus_influenzae ---l--k--ar--d--t--dpa-l-g-q-g-g-l-l--------- B Neisseria_gonorrhoeae ---v--e--da--q--av-r-a-t-d-p-a-l-g-qag--ll--- B Neisseria_meningitidis ---e--d--aq--a--a--r-a-t-d-p-a-l-g-qag--ll--- B Nitrosomonas_europaea -a-l--s--ev--d------------------------------- B Nitrosomonas_eutropha ---p--m--ge--v--g---------------------------- B Photorhabdus_luminescens ---i--k--g----------------------------------- B Pseudomonas_aeruginosa ---k--l--d----------------------------------- B Streptomyces_coelicolor ---l--a--ag--n--l---------------------------- B Vibrio_fischeri ------d--vs--e--f--n------------------------- B Vibrio_parahaemolyticus ---a--k-------------------------------------- B Yersinia_pestis ---n----------------------------------------- =============================================================================== B MICROCOCCUS_LUTEUS --h--e---gd--g-i--p-g-v-e-a-g-g-e-a---ri----- B Thermobifida_fusca --h--e---------i--a-r------------------------ =============================================================================== B HELICOBACTER_PYLORI --h-qk-mm---k--d--m-hg-k-d-m-h-h-t--kk---kk-- B Helicobacter_pylori-CAA94567 --h-qk-mm---k--d--m-hg-k-d-m-h-h-t--kk---kk-- B Helicobacter_pylori-CATA --h-qk-mm---k--d--m-hg-k-d-m-h-h-t--kk---kk-- B Helicobacter_pylori-CATA_HELPJ --h-qk-mm---k--d--m-ha-k-d-m-h-h-m--kk---kk-- =============================================================================== B ENTEROCOCCUS_FAECALIS --q--a--------------------------------------- B Bacillus_licheniformis --s--v-pq--ev-------------------------------- B Bacillus_subtilis --d--s--------------------------------------- B Oceanobacillus_iheyensis --q--v-pe--sv-k------------------------------ =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 640 650 660 670 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxx ========================================== * S_CEREVISIAE -------- * Candida_albicans -------- * Candida_dubliniensis -------- * Candida_glabrata -------- * Candida_tropicalis -------- * Debaryomyces_hansenii -------- * Eremothecium_gossypii -------- * Kluyveromyces_lactis -------- ========================================== * BOVINE -------- * HUMAN laarekan * Anopheles_gambiae -------- * Apis_mellifera l------- * Ascaris_lumbricoides mmpcaidd * Bombyx_mandarina -------- * C_elegans -------- * Canis_lupus laarekan * Cavia_porcellus lsakekan * Danio_rerio vaaaskm- * D_melanogaster -------- * D_pseudoobscura -------- * Chicken vsakersn * Litopenaeus_vannamei -------- * Pongo_pygmaeus laarekan * Rat iaakgkan * Pig -------- * X_laevis atskdkan * X_tropicalis atakdkan * Mouse-CATA maakgkan * Mouse-Q3TXQ6 maakgkan ========================================== B PROTEUS_MIRABILIS -------- B 1H6NA_Proteus_mirabilis -------- B 1H7KA_Proteus_mirabilis -------- B Acinetobacter_calcoaceticus -------- B Actinobacillus_pleuropneumoniae -------- B Actinobacillus_succinogenes -------- B Bordetella_pertussis -------- B Chromobacterium_violaceum -------- B Colwellia_psychrerythraea -------- B Cupriavidus_metallidurans -------- B Desulfotalea_psychrophila -------- B Haemophilus_influenzae -------- B Neisseria_gonorrhoeae -------- B Neisseria_meningitidis -------- B Nitrosomonas_europaea -------- B Nitrosomonas_eutropha -------- B Photorhabdus_luminescens -------- B Pseudomonas_aeruginosa -------- B Streptomyces_coelicolor -------- B Vibrio_fischeri -------- B Vibrio_parahaemolyticus -------- B Yersinia_pestis -------- ========================================== B MICROCOCCUS_LUTEUS -------- B Thermobifida_fusca -------- ========================================== B HELICOBACTER_PYLORI -------- B Helicobacter_pylori-CAA94567 -------- B Helicobacter_pylori-CATA -------- B Helicobacter_pylori-CATA_HELPJ -------- ========================================== B ENTEROCOCCUS_FAECALIS -------- B Bacillus_licheniformis -------- B Bacillus_subtilis -------- B Oceanobacillus_iheyensis -------- ========================================== Consensus xxxxxxxx

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