CCAPD: Alignment of Cellulase A (glycosyl hydrolase 5; exo-1,3-beta-glucanase)

10 20 30 40 50 60 70 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus xxxxxxxlxxslxilxxxxxxxxvxxxxxssxqxxxxxkrxxxxxxxWDYxNxxxxDxIRGVNLGGWFVL ================================================================================================== * CANDIDA_ALBICANS --qlsfiLtsSVfILllef-vkasvisnpfkpngnlkfKRggghnvaWDYdN----NvIRGVNLGGWFVL * 1EQPA_Candida_albicans ----------------------------------------------aWDYdN----NvIRGVNLGGWFVL * Candida_oleophila --lltf---apIfLLi------ss-----ivaaptlqlQRkg---leWDYqN----DkIRGVNLGGWFVL * Debaryomyces_hansenii --viassVagh---LmaifaiigIcvaapfTpKngklvKKdsg----FDYqN----DkIRGVNLGGWFVL * Debaryomyces_occidentalis --------nlTLlLLalif-spsLifslpTanKvkl-vKKg----lnWDYqN----akIhGVNLGGWFVL * Candida_albicans-EXG --qlsfiLtsSVfILllef-vkasvisnpfkpngnlkfKRggghnvaWDYdN----NvIRGVNLGGWFVL * Candida_albicans-Q5AIZ3 --qlsfiLtsSVfILllef-vkasvisnpfkpngnlkfKRggghnvaWDYdN----NvIRGVNLGGWFVL ================================================================================================== * S_CEREVISIAE --lslktLlcTLlt-vssvlatpVpardpSSiQfvhe----enkkryYDYdHgslgEpIRGVNIGGWlLL * Candida_glabrata vsfsfatIvaaLsV-salakpviapknkdTSlhfv-------nekryYDYdSkaigEpIRGVNIGGWFVL * Saccharomyces_kluyveri l-lsllfLlsTf---afgaltqpVpakseNNvQflhs----knkkrfYDYs----tElIRGVNIGGWlLL * S_cerevisiae-EXG1 --lslktLlcTLlt-vssvlatpVpardpSSiQfvhe----enkkryYDYdHgslgEpIRGVNIGGWlLL * S_cerevisiae-EXG_SACBA --lslktLlcTLlt-vssvianpVpardpSSiQfvhe----enkkryYDYdNgalgEpIRGVNIGGWlVL ================================================================================================== Consensus xxxxxxxlxxslxilxxxxxxxxvxxxxxssxqxxxxxkrxxxxxxxWDYxNxxxxDxIRGVNLGGWFVL 80 90 100 110 120 130 140 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus EPYMTPSLFExFQxNxDNDxGVPVDEYHWxQxLGKExAKxRLQxHWSSWYTEQDFxxIxNxGLNLVRIPI ================================================================================================== * CANDIDA_ALBICANS EPYMTPSLFEpFQ-NgNDqsGVPVDEYHWtQtLGKEaAlriLQkHWSTWiTEQDFkqIsNlGLNfVRIPI * 1EQPA_Candida_albicans EPYMTPSLFEpFQ-NgNDqsGVPVDEYHWtQtLGKEaAsriLQkHWSTWiTEQDFkqIsNlGLNfVRIPI * Candida_oleophila EPYITPSLFsvWs-NgEDDlntPVDEYHYtQkLGKEtAlsRLEaHWSSWYTEaDFaqMkylGINaVRIPI * Debaryomyces_hansenii EPYMTPSLFQ--Q-N-aDDgnIPVDEYHYcEkLGKDvcKqRLEtHWdNWiTEdDiakIsklGLNMVRIPI * Debaryomyces_occidentalis EPFITPSLFDiYs-kpNDDsqVPVDEYHFtQkLGKDaAQqvLEqHWkTWYkEnDFkmMlkyGLNaVRIPI * Candida_albicans-EXG EPYMTPSLFEpFQ-NgNDqsGVPVDEYHWtQtLGKEaAlriLQkHWSTWiTEQDFkqIsNlGLNfVRIPI * Candida_albicans-Q5AIZ3 EPYMTPSLFEpFQ-NgNDqsGVPVDEYHWtQtLGKEaAsriLQkHWSTWiTEQDFkqIsNlGLNfVRIPI ================================================================================================== * S_CEREVISIAE EPYITPSLFEaFRtNdDNDeGIPVDEYHFcQyLGKDlAKsRLQsHWSTFYqEQDFanIaSqGfNLVRIPI * Candida_glabrata EPYITPSLFEaFRtNpyNDdGIPVDEYHYcEqLGEQeARnRLEyHWSTFYTEQDFadIkSkGfNLVRIPI * Saccharomyces_kluyveri EPYITPSLFEaFRtDeNSDaGIPVDEYHYcEaLGsEvAEsRLEaHWSTFYTEQDFknIaSaGLNMVRIPI * S_cerevisiae-EXG1 EPYITPSLFEaFRtNdDNDeGIPVDEYHFcQyLGKDlAKsRLQsHWSTFYqEQDFanIaSqGfNLVRIPI * S_cerevisiae-EXG_SACBA EPYITPSLFEaFRtNdNNDdGIPVDEYHYcQyLGnDlAKsRLQsHWSTFYqEQDFanIaSqGfNLVRIPI ================================================================================================== Consensus EPYMTPSLFExFQxNxDNDxGVPVDEYHWxQxLGKExAKxRLQxHWSSWYTEQDFxxIxNxGLNLVRIPI 150 160 170 180 190 200 210 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus GYWAFQxLDNDPYVQxGQEQYLEKALEWAKNHNIRVWIDLHGAPGSQNGFDNSGLRDSYxFQExDNLQIT ================================================================================================== * CANDIDA_ALBICANS GYWAFQlLDNDPYVQ-GQvQYLEKALgWARkNNIRVWIDLHGAPGSQNGFDNSGLRDSYnFQngDNtQVT * 1EQPA_Candida_albicans GYWAFQlLDNDPYVQ-GQvQYLEKALgWARkNNIRVWIDLHGAPGSQNGFDNSGLRDSYnFQngDNtQVT * Candida_oleophila GYWAFQlLDNDPYVQ-GQvKYLDQALEWcRNNgLyaWVDLHGAPGSQNGFDNSGLRDSYkFQDdDDVKVT * Debaryomyces_hansenii GYWAYQtLDSDPYVQ-GQDKYLKKALKWcRNHNVKVWIDLHGAPGSQNGFDNSGLRDeYgFQsgDNtQIT * Debaryomyces_occidentalis GYWAFKlLDyDPYVQ-GQvKYLDRALDWARkyNLKVWIDLHGAPGSQNGFDNSGLRDSlgFQQgNNVnfT * Candida_albicans-EXG GYWAFQlLDNDPYVQ-GQvQYLEKALgWARkNNIRVWIDLHGAPGSQNGFDNSGLRDSYnsQngDNtQVT * Candida_albicans-Q5AIZ3 GYWAFQlLDNDPYVQ-GQvQYLEKALgWARkNNIRVWIDLHGAPGSQNGFDNSGLRDSYnFQngDNtQVT ================================================================================================== * S_CEREVISIAE GYWAFQiLDDDPYVsglQEsYLDQAIgWARNNSLKVWVDLHGAaGSQNGFDNSGLRDSYkFlEdsNLaVT * Candida_glabrata GYWAFKdMpNDPYVKgsQEyYLDQAIQWAENNgLKVWVDLHGAvGSQNGFDNSGLRDSidFladENLQnT * Saccharomyces_kluyveri GYWAFKtLDSDPYVtgkQEsYLDKAIQWsKDagLKVWVDLHGAPGSQNGFDNSGLRDhWsFlEdENLnLT * S_cerevisiae-EXG1 GYWAFQtLDDDPYVsglQEsYLDQAIgWARNNSLKVWVDLHGAaGSQNGFDNSGLRDSYkFlEdsNLaVT * S_cerevisiae-EXG_SACBA GYWAFatLDNDPYVtglQEsYLDQAIgWARNNSLKVWVDLHGAaGSQNGFDNSGLRDSYeFlEdsNLaVT ================================================================================================== Consensus GYWAFQxLDNDPYVQxGQEQYLEKALEWAKNHNIRVWIDLHGAPGSQNGFDNSGLRDSYxFQExDNLQIT 220 230 240 250 260 270 280 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus lDVLxxIxKKYGGxEYxDvVIGIELLNEPLGPVLNMDKLKQxFFxxGYExLRnxxGSVxxxQxVIIHDAF ================================================================================================== * CANDIDA_ALBICANS LNVLntIfKKYGGnEYsDVVIGIELLNEPLGPVLNMDKLKQ-FFldGYnsLRq-tGSV---tpVIIHDAF * 1EQPA_Candida_albicans LNVLntIfKKYGGnEYsDVVIGIELLNEPLGPVLNMDKLKQ-FFldGYnsLRq-tGSV---tpVIIHDAF * Candida_oleophila LEVLktIgaKYGGsDYeDVVIGIELLNEPLGPVLDMDgLRQ-FYqdGYseIRN-ndgVesynaIIIHDAF * Debaryomyces_hansenii LDVLaqIlEKYGGsDYeDVVIGIELLNEPLGtVLDMDKLKt-FFygGYKtVRN-sG-V---QtVVIHDAF * Debaryomyces_occidentalis LEVLeiIgKKYGGpEYeDVVIGIELLNEPLGPsLDLNyLKE-FFqqGYQnLRN-sGSV---QaVIIqDAF * Candida_albicans-EXG LNVLntIfKKYGGnEYsDVVIGIELLNEPLGPVLNMDKLKQ-FFldGYnsLRq-tGSV---tpVIIHDAF * Candida_albicans-Q5AIZ3 LNVLntIfKKYGGnEYsDVVIGIELLNEPLGPVLNMDKLKQ-FFldGYnsLRq-tGSV---tpVIIHDAF ================================================================================================== * S_CEREVISIAE INVLnyIlKKYsaeEYlDIVIGIELINEPLGPVLDMDKMKndYlapaYEyLRNnikSd---QvIIIHDAF * Candida_glabrata kEILkyVlQKYsqqQYlNtVIGVELINEPLGPVIDMDKMKEqYikpaYEyLRNelqSI---QdIIVHDAF * Saccharomyces_kluyveri kEVIkyLlEKYsreEYlDtVIGIELINEPLGPVLDMDKLK-eYYqfGYDyLRNelGSd---QiVVIHDAF * S_cerevisiae-EXG1 tNVLnyIlKKYsaeEYlDtVIGIELINEPLGPVLDMDKMKndYlapaYEyLRNnikSd---QvIIIHDAF * S_cerevisiae-EXG_SACBA tkaLnyIlKKYsaeEYlDtVIGIELINEPLGPVLDMDKMKndYllpaYEyLRNtieSn---QiIIMHDAF ================================================================================================== Consensus lDVLxxIxKKYGGxEYxDvVIGIELLNEPLGPVLNMDKLKQxFFxxGYExLRnxxGSVxxxQxVIIHDAF 290 300 310 320 330 340 350 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus QxFNxYWNNFLTVxxGYWNVVVDHHHYQVFSxxELERNINEHIxVACEWGxxxxxESHWnVAGEWSAALT ================================================================================================== * CANDIDA_ALBICANS QvFg-YWNNFLTVaeGqWNVVVDHHHYQVFSggELsRNINDHIsVACnWGwdakkESHWNVAGEWSAALT * 1EQPA_Candida_albicans QvFg-YWNNFLTVaeGqWNVVVDHHHYQVFSggELsRNINDHIsVACnWGwdakkESHWNVAGEWSAALT * Candida_oleophila QqtDhYWDNFMqVsgGYWNVVVDHHHYQVFdqaaLEllIeDHIktACnWGtthkdEaHWNIvGEWSsALT * Debaryomyces_hansenii Qdmg-FWNNdfnppnkYWDVVVDHHHYQVFSqdDLEKSIDEHVetvCQWGrsateESHWNVvGEWSAALT * Debaryomyces_occidentalis Qpmg-YWDNFLTL-dqYWNVVVDHHHYQVFSagELQRSIDDHItVACnWGwdakkEyHWNVAGEWSAALT * Candida_albicans-EXG QvFg-YWNNFLTVaeGqWNVVVDHHHYQVFSggELsRNINDHIsVACnWGwdakkESHWNVAGEWSAALT * Candida_albicans-Q5AIZ3 QvFg-YWNNFLTVaeGqWNVVVDHHHYQVFSggELsRNINDHIsVACnWGwdakkESHWNVAGEWSAALT ================================================================================================== * S_CEREVISIAE QpYN-YWDDFMTendGYWgVtIDHHHYQVFasdQLERSIDEHIkVACEWGtgvlnESHWiVcGEFaAALT * Candida_glabrata QpFH-YWDDFMTVdtGYWgVVIDHHHYQVFStgELQRDMgQHIqVACEWGsgiltESHWtVAGEWSAALT * Saccharomyces_kluyveri EaYN-YWDStLTVedGsWgVVVDHHHYQcFSsdQLaRSIDEHVsVACEWGtgvltESHWtVAGEWSAALT * S_cerevisiae-EXG1 QpYN-YWDDFMTendGYWgVtIDHHHYQVFasdQLERSIDEHIkVACEWGtgvlnESHWtVcGEFaAALT * S_cerevisiae-EXG_SACBA QqFN-YWDDFMTetdGYWgVtIDHHHYQVFdssQLEsSMDEHIqVACQWGtgvldEaHWtVcGEFaAALT ================================================================================================== Consensus QxFNxYWNNFLTVxxGYWNVVVDHHHYQVFSxxELERNINEHIxVACEWGxxxxxESHWnVAGEWSAALT 360 370 380 390 400 410 420 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus DCaKWLNGVGxGARYEGNYdxxxxSSPYIGSCxNxxDIxxWSDExKSDxRRYIEAQLDAFExxGGWIFWx ================================================================================================== * CANDIDA_ALBICANS DCAKWLNGVnrGARYEGaYD----NaPYIGSCqpllDIsqWSDEhKTDtRRYIEAQLDAFEytGGWVFWs * 1EQPA_Candida_albicans DCAKWLNGVnrGARYEGaYD----NaPYIGSCqpllDIsqWSDEhKTDtRRYIEAQLDAFEytGGWVFWs * Candida_oleophila DCAKWLNGVGhGARWsGNYD----NcPYIdSClSytDLsgWTDEyKTNvRKYtEAQLDAWEqvGGWfFWc * Debaryomyces_hansenii DCAtWLNGVGrGARYsGDFD----NTPYIGSCdNylDygsWSNDyRTNvRKYIEAQLDAYEqgaGWIFWs * Debaryomyces_occidentalis DCARWLNGVGrGARFsGDFD----NSPYfGSCdcyvNIatWpsEyRTNvRRYIEAQLDAFEqtGGWfFWn * Candida_albicans-EXG DCAKWLNGVnrGARYEGaYD----NaPYIGSCqpmlDIsqWSDEhKTDtRRYIEAQLDAFEytGGWVFWs * Candida_albicans-Q5AIZ3 DCAKWLNGVnrGARYEGaYD----NaPYIGSCqpllDIsqWSDEhKTDtRRYIEAQLDAFEytGGWVFWs ================================================================================================== * S_CEREVISIAE DCiKWLNsVGfGARYDGSWvngdqTSsYIGSCaNndDIayWSDErKeNtRRYVEAQLDAFEmrGGWIiWc * Candida_glabrata DCtKWLNGVGiGARYDGSFwkngvSSsFIGSCaNneDIysWSEErKeNtRKYIEAQLDAFEkrGGWIFWc * Saccharomyces_kluyveri DCAKWINGVGyGARYDGSFtkdseSSyYIGSCeNneDVstWSEErKSNnRKYVEAQLDAFElrGGWIFWc * S_cerevisiae-EXG1 DCtKWLNsVGfGARYDGSWvngdqTSsYIGSCaNndDIayWSDErKeNtRRYVEAQLDAFEmrGGWIiWc * S_cerevisiae-EXG_SACBA DCtKWVNsVGfGARYDGSWvngdeTStYIGSCaNndDItsWSDQrKeNtRRYVEAQLDAFEmrGGWIiWc ================================================================================================== Consensus DCaKWLNGVGxGARYEGNYdxxxxSSPYIGSCxNxxDIxxWSDExKSDxRRYIEAQLDAFExxGGWIFWx 430 440 450 460 470 480 490 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus WKTESxLEWDxQxLMxxGLFPQPLTDRQFPNQCGfxxx ================================================================== * CANDIDA_ALBICANS WKTENapEWsfQtLtynGLFPQPVTDRQFPNQCGFh-- * 1EQPA_Candida_albicans WKTENapEWsfQtLtynGLFPQPVTDRQFPNQCGFh-- * Candida_oleophila WKTESapEWDfQaLtnaGLiPQPLnDRQYPNQCGY--- * Debaryomyces_hansenii WKTENaVEWDfsrLtqaGIFPsPVTDRtYeNQCGF--- * Debaryomyces_occidentalis WKcENaIEWDlQgLItaGVFPyPfyNRQFPNQCGF--- * Candida_albicans-EXG WKTENapEWsfQtLtynGLFPQPVTDRQFPNQCGFh-- * Candida_albicans-Q5AIZ3 WKTENapEWsfQtLtynGLFPQPVTDRQFPNQCGFh-- ================================================================== * S_CEREVISIAE YKTESsLEWDaQrLMfnGLFPQPLTDRKYPNQCGtisn * Candida_glabrata YKTETnIEWDasrLIeyGMFPQPLTDRRYPgQCa---- * Saccharomyces_kluyveri YKTETtVEWDlQrLMysGLFPQPVTDRQYPNQCGF--- * S_cerevisiae-EXG1 YKTESsLEWDaQrLMfnGLFPQPLTDRKYPNQCGtisn * S_cerevisiae-EXG_SACBA YKTESsLEWDvQrLMynGLFPQPLTDRQYPNQCnttss ================================================================== Consensus WKTESxLEWDxQxLMxxGLFPQPLTDRQFPNQCGfxxx

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