CCAPD: Alignment of Copper/Zinc-containing SuperOxide Dismutase (Copper/Zinc SOD)

10 20 30 40 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx =============================================================================== * SCHISTOSOMA_MANSONI ------------------gs-n----------------------- * Schistosoma_japonicum --------------------------------------------- =============================================================================== * S_CEREVISIAE --------------------------------------------- * 1B4TA_S_cerevisiae --------------------------------------------- * 1F18A_S_cerevisiae --------------------------------------------- * 1F1AA_S_cerevisiae --------------------------------------------- * 1F1DA_S_cerevisiae --------------------------------------------- * 1JK9C_S_cerevisiae --------------------------------------------- * Aspergillus_flavus --------------------------------------------- * Aspergillus_fumigatus --------------------------------------------- * Candida_albicans --------------------------------------------- * Candida_glabrata --------------------------------------------- * Chaetomium_globosum --------------------------------------------- * Chaetomium_thermophilum --------------------------------------------- * Coccidioides_immitis svmlsvkkgldlqawaaadlp-gevdpalpkwseqptsprgsrpf * Cryptococcus_neoformans --------------------------------------------- * Debaryomyces_hansenii --------------------------------------------- * Emericella_nidulans --------------------------------------------- * Eremothecium_gossypii --------------------------------------------- * Gibberella_zeae niklth--------------------------------------- * Kluyveromyces_lactis --------------------------------------------- * Neurospora_crassa --------------------------------------------- * Schizosaccharomyces_pombe --------------------------------------------- * Yarrowia_lipolytica --------------------------------------------- =============================================================================== * HUMAN ---------------------a----------------------- * X_LAEVIS --------------------------------------------- * BOVINE ---------------------a----------------------- * 1AZVA_Human ---------------------a----------------------- * 1FUNA_Human ---------------------a----------------------- * 1L3NA_Human ---------------------a----------------------- * 1N19A_Human ---------------------a----------------------- * 1PTZA_Human ---------------------a----------------------- * 1CB4A_Bovine ---------------------a----------------------- * 1E9OA_Bovine ---------------------a----------------------- * 1E9OB_Bovine ---------------------a----------------------- * 1E9PA_Bovine ---------------------a----------------------- * 1E9PB_Bovine ---------------------a----------------------- * 3SODO_Bovine ---------------------a----------------------- * Apis_mellifera --------------------------------------------- * Canis_lupus ---------------------e----------------------- * Capra_hircus ---------------------a----------------------- * Cavia_porcellus ---------------------a----------------------- * Cebus_apella ---------------------a----------------------- * Chelonia_mydas -----------------a---t----------------------- * Danio_rerio ---------------------v----------------------- * Horse ---------------------a----------------------- * Chicken -----------------a---t----------------------- * Hylobates_lar ---------------------a----------------------- * Ixodes_scapularis ---------------------s----------------------- * Macaca_mulatta ---------------------a----------------------- * Monodelphis_domestica ---------------------v----------------------- * Mouse ---------------------a----------------------- * Oncorhynchus_mykiss ---------------------a----------------------- * Rabbit ---------------------a----------------------- * Ovis_aries ---------------------a----------------------- * Pongo_pygmaeus ---------------------a----------------------- * Rat ---------------------a----------------------- * Pig ---------------------a----------------------- * Tetraodon_nigroviridis fpasavlpcvsflevttakm-v----------------------- * X_tropicalis --------------------------------------------- * Cervus_elaphus-SODC ---------------------a----------------------- * Cervus_elaphus-SODC_VAR ---------------------a----------------------- * X_laevis-SODC1 --------------------------------------------- * X_laevis-SODC2 --------------------------------------------- * Bovine-SODC_BOSMU ---------------------a----------------------- =============================================================================== B PHOTOBACTERIUM_LEIOGNATHI ---------------------n----------------------- B 1IB5A_Photobacterium_leiognathi --------------------------------------------- B 1IBBA_Photobacterium_leiognathi --------------------------------------------- B 1IBDA_Photobacterium_leiognathi --------------------------------------------- B 1IBFA_Photobacterium_leiognathi --------------------------------------------- B 1IBHA_Photobacterium_leiognathi --------------------------------------------- B 1YAIB_Photobacterium_leiognathi --------------------------------------------- B 1YAIC_Photobacterium_leiognathi --------------------------------------------- B Vibrio_alginolyticus --------------------------------------------- B Vibrio_splendidus --------------------------------------------- B Vibrio_vulnificus ---------------------n----------------------- =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 50 60 70 80 90 ----|----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx =============================================================================== * SCHISTOSOMA_MANSONI --------------------------------------------- * Schistosoma_japonicum --------------------------------------------- =============================================================================== * S_CEREVISIAE --------------------------------------------- * 1B4TA_S_cerevisiae --------------------------------------------- * 1F18A_S_cerevisiae --------------------------------------------- * 1F1AA_S_cerevisiae --------------------------------------------- * 1F1DA_S_cerevisiae --------------------------------------------- * 1JK9C_S_cerevisiae --------------------------------------------- * Aspergillus_flavus --------------------------------------------- * Aspergillus_fumigatus --------------------------------------------- * Candida_albicans --------------------------------------------- * Candida_glabrata --------------------------------------------- * Chaetomium_globosum --------------------------------------------- * Chaetomium_thermophilum --------------------------------------------- * Coccidioides_immitis dgrrvdlalflvnplkpplvtppprslgservgayrwalrrllva * Cryptococcus_neoformans --------------------------------------------- * Debaryomyces_hansenii --------------------------------------------- * Emericella_nidulans --------------------------------------------- * Eremothecium_gossypii --------------------------------------------- * Gibberella_zeae --------------------------------------------- * Kluyveromyces_lactis --------------------------------------------- * Neurospora_crassa --------------------------------------------- * Schizosaccharomyces_pombe --------------------------------------------- * Yarrowia_lipolytica --------------------------------------------- =============================================================================== * HUMAN --------------------------------------------- * X_LAEVIS --------------------------------------------- * BOVINE --------------------------------------------- * 1AZVA_Human --------------------------------------------- * 1FUNA_Human --------------------------------------------- * 1L3NA_Human --------------------------------------------- * 1N19A_Human --------------------------------------------- * 1PTZA_Human --------------------------------------------- * 1CB4A_Bovine --------------------------------------------- * 1E9OA_Bovine --------------------------------------------- * 1E9OB_Bovine --------------------------------------------- * 1E9PA_Bovine --------------------------------------------- * 1E9PB_Bovine --------------------------------------------- * 3SODO_Bovine --------------------------------------------- * Apis_mellifera --------------------------------------------- * Canis_lupus --------------------------------------------- * Capra_hircus --------------------------------------------- * Cavia_porcellus --------------------------------------------- * Cebus_apella --------------------------------------------- * Chelonia_mydas --------------------------------------------- * Danio_rerio --------------------------------------------- * Horse --------------------------------------------- * Chicken --------------------------------------------- * Hylobates_lar --------------------------------------------- * Ixodes_scapularis --------------------------------------------- * Macaca_mulatta --------------------------------------------- * Monodelphis_domestica --------------------------------------------- * Mouse --------------------------------------------- * Oncorhynchus_mykiss --------------------------------------------- * Rabbit --------------------------------------------- * Ovis_aries --------------------------------------------- * Pongo_pygmaeus --------------------------------------------- * Rat --------------------------------------------- * Pig --------------------------------------------- * Tetraodon_nigroviridis --------------------------------------------- * X_tropicalis --------------------------------------------- * Cervus_elaphus-SODC --------------------------------------------- * Cervus_elaphus-SODC_VAR --------------------------------------------- * X_laevis-SODC1 --------------------------------------------- * X_laevis-SODC2 --------------------------------------------- * Bovine-SODC_BOSMU --------------------------------------------- =============================================================================== B PHOTOBACTERIUM_LEIOGNATHI --------------------------------------------- B 1IB5A_Photobacterium_leiognathi --------------------------------------------- B 1IBBA_Photobacterium_leiognathi --------------------------------------------- B 1IBDA_Photobacterium_leiognathi --------------------------------------------- B 1IBFA_Photobacterium_leiognathi --------------------------------------------- B 1IBHA_Photobacterium_leiognathi --------------------------------------------- B 1YAIB_Photobacterium_leiognathi --------------------------------------------- B 1YAIC_Photobacterium_leiognathi --------------------------------------------- B Vibrio_alginolyticus --------------------------------------------- B Vibrio_splendidus --------------------------------------------- B Vibrio_vulnificus --------------------------------------------- =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 100 110 120 130 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxxxxxvqAVCVLKGExxxxxxxxxxxx =============================================================================== * SCHISTOSOMA_MANSONI -----------------------MKAVCVMtGt--a--------- * Schistosoma_japonicum ------------------------KAVCVMsGs--a--------- =============================================================================== * S_CEREVISIAE -----------------------VQAVaVLKGD--a--------- * 1B4TA_S_cerevisiae -----------------------VQAVaVLKGD--a--------- * 1F18A_S_cerevisiae -----------------------VQAVaVLKGD--a--------- * 1F1AA_S_cerevisiae -----------------------VQAVaVLKGD--a--------- * 1F1DA_S_cerevisiae -----------------------VQAVaVLKGD--a--------- * 1JK9C_S_cerevisiae -----------------------VQAVaVLKGD--a--------- * Aspergillus_flavus -----------------------VKAVaVLRGD--s--------- * Aspergillus_fumigatus -----------------------VKAVaVLRGD--s--------- * Candida_albicans -----------------------VKAVaVVRGD--s--------- * Candida_glabrata -----------------------VKAVaVLRGs--a--------- * Chaetomium_globosum -----------------------VKAVaVVRGD--s--------- * Chaetomium_thermophilum -----------------------VKAVaVVRGD--s--------- * Coccidioides_immitis lfcsrsfermvdspelglpplswwppVaVLRGD--s--------- * Cryptococcus_neoformans -----------------------VKAVaVLKGD--s--------- * Debaryomyces_hansenii -----------------------VQAVaVLRGD--s--------- * Emericella_nidulans -----------------------VKAVaVLRGD--s--------- * Eremothecium_gossypii -----------------------VKAVaVLKGD--a--------- * Gibberella_zeae -----------------------slAVsVLRGD--s--------- * Kluyveromyces_lactis -----------------------VnAVaVLKGD--s--------- * Neurospora_crassa -----------------------VKAVaVVRGD--s--------- * Schizosaccharomyces_pombe -----------------------VRAVaVLRGD--s--------- * Yarrowia_lipolytica -----------------------VKAVaVLRGD--s--------- =============================================================================== * HUMAN -----------------------tKAVCVLKGD--g--------- * X_LAEVIS -----------------------VKAVCVLaGs--g--------- * BOVINE -----------------------tKAVCVLKGD--g--------- * 1AZVA_Human -----------------------tKAVCVLKGD--g--------- * 1FUNA_Human -----------------------tKAVaVLKGD--g--------- * 1L3NA_Human -----------------------tKAVaVLKGD--g--------- * 1N19A_Human -----------------------tKvVaVLKGD--g--------- * 1PTZA_Human -----------------------tKAVaVLKGD--g--------- * 1CB4A_Bovine -----------------------tKAVCVLKGD--g--------- * 1E9OA_Bovine -----------------------tsAVCVLsGD--g--------- * 1E9OB_Bovine -----------------------tKAVCVLKGD--g--------- * 1E9PA_Bovine -----------------------tsAVCVLsGD--g--------- * 1E9PB_Bovine -----------------------tsAVCVLsGD--g--------- * 3SODO_Bovine -----------------------tKAVaVLKGD--g--------- * Apis_mellifera -----------------------tKAVCVLQGE------------ * Canis_lupus -----------------------MKAVCVLKGQ--g--------- * Capra_hircus -----------------------tKAVCVLKGD--g--------- * Cavia_porcellus -----------------------tKAVCVLKGD--g--------- * Cebus_apella -----------------------MKAVCVLKGD--g--------- * Chelonia_mydas -----------------------VKAVCVLKGE--dpvkepvkgp * Danio_rerio -----------------------nKAVCVLKGt--g--------- * Horse -----------------------LKAVCVLKGD--g--------- * Chicken -----------------------LKAVCVMKGD--a--------- * Hylobates_lar -----------------------MKAVCVLKGD--s--------- * Ixodes_scapularis -----------------------VKAVCVLKGs--e--------- * Macaca_mulatta -----------------------MKAVCVLKGD--s--------- * Monodelphis_domestica -----------------------LKAVCVLKGD--g--------- * Mouse -----------------------MKAVCVLKGD--g--------- * Oncorhynchus_mykiss -----------------------MKAVCVLKGt--g--------- * Rabbit -----------------------tKAVCVLKGD--g--------- * Ovis_aries -----------------------tKAVCVLKGD--g--------- * Pongo_pygmaeus -----------------------tKAVCVLKGD-ns--------- * Rat -----------------------MKAVCVLKGD--g--------- * Pig -----------------------tKAVCVLKGD--g--------- * Tetraodon_nigroviridis -----------------------IKAVCVLKGa--g--------- * X_tropicalis -----------------------VRAVCVLaGs--g--------- * Cervus_elaphus-SODC -----------------------tKAVCVLKGD--g--------- * Cervus_elaphus-SODC_VAR -----------------------tKAVCVMKGD--g--------- * X_laevis-SODC1 -----------------------VKAVCVLaGs--g--------- * X_laevis-SODC2 -----------------------VKAVCVLaGs--g--------- * Bovine-SODC_BOSMU -----------------------tKAVCVLKGD--g--------- =============================================================================== B PHOTOBACTERIUM_LEIOGNATHI ---kaktllftalafglshqalaqdltvkMtdlqtg--------- B 1IB5A_Photobacterium_leiognathi -----------------------qdltvkMtdlqtg--------- B 1IBBA_Photobacterium_leiognathi -----------------------qdltvkMtdlqtg--------- B 1IBDA_Photobacterium_leiognathi -----------------------qdltvkMtdlqtg--------- B 1IBFA_Photobacterium_leiognathi -----------------------qdltvkMtdlqtg--------- B 1IBHA_Photobacterium_leiognathi -----------------------qdltvkMtdlqtg--------- B 1YAIB_Photobacterium_leiognathi -----------------------qdltvkMtdlqtg--------- B 1YAIC_Photobacterium_leiognathi ------------------------dltvkMtdlqtg--------- B Vibrio_alginolyticus ----lkgllcisvasalvaapnaLaktveMtalntn--------- B Vibrio_splendidus ----nkttwlaalal-isspvfaevvnveMidlgsg--------- B Vibrio_vulnificus ---k-htllaaillyst--ssfaqslsvdMKdlssn--------- =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxvqAVCVLKGExxxxxxxxxxxx 140 150 160 170 180 ----|----:----|----:----|----:----|----:----| Consensus xxxxVqGTIxFExxQExxxxxxxxPVxISGEISGLxxDGEHGFHV =============================================================================== * SCHISTOSOMA_MANSONI ---gVKGvVkFt--QE--tdng--PVhVhaEfSGLk-aGKHGFHV * Schistosoma_japonicum ---gVKGvVnFt--QD--ttdg--PVhIhGEfSGLk-pGKHGFHV =============================================================================== * S_CEREVISIAE ---gVsGvVkFE--Qa--sese--PttVSyEIaGnspNaErGFHI * 1B4TA_S_cerevisiae ---gVsGvVkFE--Qa--sese--PttVSyEIaGnspNaErGFHI * 1F18A_S_cerevisiae ---gVsGvVkFE--Qa--sese--PttVSyEIaGnspNaErGFHI * 1F1AA_S_cerevisiae ---gVsGvVkFE--Qa--sese--PttVSyEIaGnspNaErGFHI * 1F1DA_S_cerevisiae ---gVsGvVkFE--Qa--sese--PttVSyEIaGnspNaErGFcI * 1JK9C_S_cerevisiae ---gVsGvVkFE--Qa--sese--PttVSyEIaGnspNaErGFHI * Aspergillus_flavus ---kIsGTVtFE--Qa--dana--PttVSwnITGhdaNaEraFHV * Aspergillus_fumigatus ---kItGTVtFE--Qa--dens--PttVSwnIkGndpNaKrGFHV * Candida_albicans ---kVQGTVhFE--QE--sesa--PttISwEIeGndpNalrGFHI * Candida_glabrata ---gVsGvVtlE--Qa--seqd--PttITyEIaGndpNaErGFHI * Chaetomium_globosum ---kVtGSIiFE--QE--sess--PttVTwDITGhdaNaKrGmHI * Chaetomium_thermophilum ---kVtGTVtFE--QE--sess--PtiITwDITGhdpNaKrGmHt * Coccidioides_immitis ---lVKGTVtFE--Qa--dens--PttISwnISGhdaNaQrGFHI * Cryptococcus_neoformans ---pVtGvItFt--QE--kega--PVtVSGDIknLdaNaErGFHV * Debaryomyces_hansenii ---kViGvVnFE--Qs--sesd--PtfITwEISGndaNalrGFHV * Emericella_nidulans ---kVsGTVtFE--Qa--dens--nttVSwnITGndpNaErGFHI * Eremothecium_gossypii ---gVsGvVhFE--QE--adaa--vttISwnITGfepNtEHGFHI * Gibberella_zeae ---kVsGTVvFE--QE--sesa--PttITwDITGndpNaKrGFHI * Kluyveromyces_lactis ---sVsGiVrFE--QE--sedq--qtkISwEITGndaNalrGFHI * Neurospora_crassa ---nVKGTViFE--QE--sesa--PttITyDISGndpNaKrGFHI * Schizosaccharomyces_pombe ---kVsGvVtFE--Qv--dqns--qVsVivDLvGndaNaKrGFHI * Yarrowia_lipolytica ---kVsGTVtFE--QD--sesg--PVtVTyDIkGndpNaErGFHV =============================================================================== * HUMAN ---pVQGiInFE--QK--esng--PVkVwGsIkGLt-EGlHGFHV * X_LAEVIS ---dVKGvVhFE--QQ--de-g--aVsVeGKIeGLt-DGlHGFHI * BOVINE ---pVQGTIhFE--aK--g--d--tVvVTGsITGLt-EGDHGFHV * 1AZVA_Human ---pVQGiInFE--QK--esng--PVkVwGsIkrLt-EGlHGFHV * 1FUNA_Human ---pVQGiInFE--QK--esng--PVkVwGsIkGLt-EGlHGFHV * 1L3NA_Human ---pVQGiInFE--QK--esng--PVkVwGsIkGLt-EGlHGFHV * 1N19A_Human ---pVQGiInFE--QK--esng--PVkVwGsIkGLt-EGlHGFHV * 1PTZA_Human ---pVQGiInFE--QK--esng--PVkVwGsIkGLt-EGlrGFHV * 1CB4A_Bovine ---pVQGTIhFE--aK--g--d--tVvVTGsITGLt-EGDHGFHV * 1E9OA_Bovine ---pVQGTIhFE--aK--g--d--tVvVTGsITGLt-EGDHGFHV * 1E9OB_Bovine ---pVQGTIhFE--aK--g--d--tVvVTGsITGLt-EGDHGFHV * 1E9PA_Bovine ---pVQGTIhFE--aK--g--d--tVvVTGsITGLt-EGDHGFHV * 1E9PB_Bovine ---pVQGTIhFE--as--g--d--tVvVTGsITGLt-EGDHGFHV * 3SODO_Bovine ---pVQGTIhFE--aK--g--d--tVvVTGsITGLt-EGDHGFHV * Apis_mellifera ----VKGTIfFE--Qp--estn--sVkVTGQVTGLk-kGlHGFHV * Canis_lupus ---pVEGTIhFv--QK--gs-g--PVvVSGtITGLt-EGEHGFHV * Capra_hircus ---pVQGTIhFE--aK--g--d--kVvVTGsITGLt-EGDHGFHV * Cavia_porcellus ---pVQGiIhFE--QK---ang--PVvVkGrITGLv-EGKHGFHV * Cebus_apella ---pVQGTInFE--QKesn--g--PVkVwGsITGLa-EGlHGFHV * Chelonia_mydas vkepVKGiIyFE--Q---qgng--PVtLSGsITGLt-EGKHGFHV * Danio_rerio ---eVtGTVyFn--QE--g--ekkPVkVTGEITGLt-pGKHGFHV * Horse ---pVhGvIhFEqqQE--g--g--PVvLkGfIeGLt-kGDHGFHV * Chicken ---pVEGvIhFQ--Q---qgsg--PVkVTGKITGLs-DGDHGFHV * Hylobates_lar ---pVQGiInFE--QKesn--g--PVkVyGrITGLt-EGlHGFHV * Ixodes_scapularis ---kttGTVyFt--Qa--gpnq--PVvVTGEITGLd-qGlHGFHV * Macaca_mulatta ---pVQGTInFE--QKesn--g--PVkVwGsITGLt-EGlHGFHV * Monodelphis_domestica ---pVQGTIfFE--QK--qvge--PVeLSGsIkGLa-EGDHGFHV * Mouse ---pVQGTIhFE--QKasg--e--PVvLSGQITGLt-EGQHGFHV * Oncorhynchus_mykiss ---eVtGTVfFE--QE--gadg--PVkLiGEISGLa-pGEHGFHV * Rabbit ---pVEaTIhFE--QK---gtg--PVvVkGrITGLt-EGlHeFHV * Ovis_aries ---pVQGTIrFE--aK--g--d--kVvVTGsITGLt-EGDHGFHV * Pongo_pygmaeus ---pVKGiInFE--QKern--g--PVkVwGsIeGLt-EGlHGFHV * Rat ---pVQGvIhFE--QKasg--e--PVvVSGQITGLt-EGEHGFHV * Pig ---pVQGTIyFE--lK---gek--tVlVTGtIkGLa-EGDHGFHV * Tetraodon_nigroviridis ---etsGTVyFE--QQ--d--ekaPVkLTGEIkGLt-aGEHGFHV * X_tropicalis ---dVKGvVhFQ--QQ--d-eg--PVtVeGKIyGLt-DGKHGFHI * Cervus_elaphus-SODC ---pVQGTIrFE--aK--g--h--tVvVTGsITGLt-EGDHGFHV * Cervus_elaphus-SODC_VAR ---pVQGTIrFE--aK--g--n--tVvVTGsITGLt-EGDHGFHV * X_laevis-SODC1 ---dVKGvVrFE--QQ--dd-g--dVtVeGKIeGLt-DGnHGFHI * X_laevis-SODC2 ---dVKGvVhFE--QQ--de-g--aVsVeGKIeGLt-DGlHGFHI * Bovine-SODC_BOSMU ---pVQGTIhFE--aK--g--d--tVvVTGsITGLt-EGDHGFHV =============================================================================== B PHOTOBACTERIUM_LEIOGNATHI ---kpvGTIels--Qn--k--y--gVvfipELadLt-pGmHGFHI B 1IB5A_Photobacterium_leiognathi ---kpvGTIels--Qn--k--y--gVvfipELadLt-pGmHGFHI B 1IBBA_Photobacterium_leiognathi ---kpvGTIels--Qn--k--y--gVvfipELadLt-pGmHGFHI B 1IBDA_Photobacterium_leiognathi ---kpvGTIels--Qn--k--y--gVafipELadLt-pGmHGFHI B 1IBFA_Photobacterium_leiognathi ---kpvGTIels--Qn--k--y--gVgfipELadLt-pGmHGFHI B 1IBHA_Photobacterium_leiognathi ---kpvGTIels--Qn--k--y--gVvfipELadLt-pGiHGFHI B 1YAIB_Photobacterium_leiognathi ---kpvGTIels--Qn--k--y--gVvfTpELadLt-pGmHGFHI B 1YAIC_Photobacterium_leiognathi ---kpvGTIels--Qn--k--y--gVvfTpELadLt-pGmHGFHI B Vibrio_alginolyticus ---esaGTIeis--Qs--d--y--gVvfTpQLSGLs-aGvHGFHV B Vibrio_splendidus ---qstGTVmis--ss--e--y--gavfTpELkdLp-vGtHGFHV B Vibrio_vulnificus ---qtlGTVtis--ss--d--y--gtvfTpDLkGLp-sGlHGFHL =============================================================================== Consensus xxxxVqGTIxFExxQExxxxxxxxPVxISGEISGLxxDGEHGFHV 190 200 210 220 ----:----|----:----|----:----|----:----|----: Consensus HQFGDNTSGxxxxxxxxCTSAGPHFNPxNKxEHGxPEDEDRHVGD =============================================================================== * SCHISTOSOMA_MANSONI HEFGDtTNG--------CTSAGaHFNPtkQ-EHGaPEDsiRHVGD * Schistosoma_japonicum HEFGDtTNG--------CTSAGaHFNPtNQ-EHGaPnDsiRHVGD =============================================================================== * S_CEREVISIAE HEFGDaTNG--------CvSAGPHFNPfkK-tHGaPtDEvRHVGD * 1B4TA_S_cerevisiae cEFGDaTNG--------CvSAGPHFNPfkK-tHGaPtDEvRHVGD * 1F18A_S_cerevisiae HEFGDaTNG--------CvSAGPHFNPfkK-tHGaPtDEvRHVGD * 1F1AA_S_cerevisiae qEFGDaTNG--------CvSAGPHFNPfkK-tHGaPtDEvRHVGD * 1F1DA_S_cerevisiae HEFGDaTNG--------CvSAGPHFNPfkK-tHGaPtDEvRHVGD * 1JK9C_S_cerevisiae fEFGDaTNG--------CvSAGPHFNPfkK-tHGaPtDEvRHVGD * Aspergillus_flavus HQFGDNTNG--------CTSAGPHFNPfgK-EHGaPEDENRHVGD * Aspergillus_fumigatus HQFGDNTNG--------CTSAGPHFNPygK-tHGaPEDsERHVGD * Candida_albicans HQFGDNTNG--------CTSAGPHFNPfgK-QHGaPEDDERHVGD * Candida_glabrata HEFGDvTNG--------CvSAGPHFNPfkK-tHGaPQDENRHVGD * Chaetomium_globosum HtFGDNTNG--------CTSAGPHFNPhgK-tHGaPvDENRHVGD * Chaetomium_thermophilum HtFGDNTNG--------CTSAGPHFNPhgK-tHGaPtDENRHVGD * Coccidioides_immitis HQFGDNTNG--------CTSAGPHYNPfSK-nHGaPsDvDRHVGD * Cryptococcus_neoformans HEFGDNTNG--------CTSAGPHFNPhgK-nHGaPsDsERHVGD * Debaryomyces_hansenii HtFGDNTNG--------CTSAGPHFNPftK-EHGaPEDDNRHVGD * Emericella_nidulans HQFGDNTNG--------CTSAGPHFNPfgK-tHGaPEDEvRHVGD * Eremothecium_gossypii HEFGDvTNG--------CTSsGsHFNPfkK-tHGsPEDENRHVGD * Gibberella_zeae HtFGDNTNG--------CTSAGPHFNPhNK-tHGaPsDEtRHVGD * Kluyveromyces_lactis HtFGDNTNG--------CTSAGPHFNPfNK-nHGaPEDEERHVGD * Neurospora_crassa HtFGDNTNG--------CTSAGPHFNPhgt-tHGdrtaEvRHVGD * Schizosaccharomyces_pombe HQFGDNTNG--------CTSAGPHFNPegK-tHGdrtaavRHVGD * Yarrowia_lipolytica HEFGDNTNG--------CTSAGPHFNPfkK-nHGgPtDsERHVGD =============================================================================== * HUMAN HEFGDNTaG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * X_LAEVIS HvFGDNTNG--------CmSAGsHFNPeNK-nHGaPgDtDRHVGD * BOVINE HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * 1AZVA_Human HEFGDNTaG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * 1FUNA_Human HEFGDNTaG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * 1L3NA_Human HEFGDNTaG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * 1N19A_Human HEFGDNTaG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * 1PTZA_Human HEFGDNTaG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * 1CB4A_Bovine HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDDERHVGD * 1E9OA_Bovine HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * 1E9OB_Bovine HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDDERHVGD * 1E9PA_Bovine HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPsDEERHVGD * 1E9PB_Bovine HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPsDDERHVGD * 3SODO_Bovine HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * Apis_mellifera HEFGDNTNG--------CTSAGaHFNPlgK-DHGgPDsDiRHVGD * Canis_lupus HQFeDxTqG--------CTSAGPHFNPlSK-KHGgPKDQERHVGD * Capra_hircus HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * Cavia_porcellus HEFGDNTqG--------CTSAGPHFNPlSK-KHGgPQDEERHVGD * Cebus_apella HQFGDNTqG--------CTSAGPHFNPlSR-KHGgPEDEERHVGD * Chelonia_mydas HEFGDNTNG--------CTSAGaHFNPpgK-nHGgPQDnERHVGD * Danio_rerio HaFGDNTNG--------CiSAGPHFNPhDK-tHGgPtDsvRHVGD * Horse HEFGDNTqG--------CTTAGaHFNPlSK-KHGgPKDEERHVGD * Chicken HEFGDNTNG--------CTSAGaHFNPegK-QHGgPKDaDRHVGD * Hylobates_lar HQFGDNTqG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * Ixodes_scapularis HEFGDNTNG--------CTSAGPHFNPlgK-EHGaPtDtNRHVGD * Macaca_mulatta HQFGDNTqG--------CTSAGPHFNPlSR-QHGgPKDEERHVGD * Monodelphis_domestica HEFGDNTqG--------CTSAGaHFNPhSK-KHGgPtDEERHVGD * Mouse HQYGDNTqG--------CTSAGPHFNPhSK-KHGgPaDEERHVGD * Oncorhynchus_mykiss HaYGDNTNG--------CmSAGPHFNPhNQ-tHGgPtDavRHVGD * Rabbit HQFGDNrqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * Ovis_aries HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * Pongo_pygmaeus HEFGDNTvG--------CTSAGPHFNPlSR-KHGgPKDEERHVGD * Rat HQYGDNTqG--------CTTAGPHFNPhSK-KHGgPaDEERHVGD * Pig HQFGDNTqG--------CTSAGPHFNPeSK-KHGgPKDQERHVGD * Tetraodon_nigroviridis HaFGDNTNG--------CiSAGPHYNPhNK-tHagPnDENRHVGD * X_tropicalis HEFGDNTNG--------CiSAGPHFNPeSK-tHGaPEDavRHVGD * Cervus_elaphus-SODC HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * Cervus_elaphus-SODC_VAR HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD * X_laevis-SODC1 HvFGDNTNG--------ClSAGPHFNPqNK-nHGsPKDaDRHVGD * X_laevis-SODC2 HvFGDNTNG--------CmSAGPHFNPeNK-nHGaPgDtDRHVGD * Bovine-SODC_BOSMU HQFGDNTqG--------CTSAGPHFNPlSK-KHGgPKDEERHVGD =============================================================================== B PHOTOBACTERIUM_LEIOGNATHI HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPwtDDnHkGD B 1IB5A_Photobacterium_leiognathi HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPytDDnHkGD B 1IBBA_Photobacterium_leiognathi HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPftDDnHkGD B 1IBDA_Photobacterium_leiognathi HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPwtDDnHkGD B 1IBFA_Photobacterium_leiognathi HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPwtDDnHkGD B 1IBHA_Photobacterium_leiognathi HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPwtDDnHkGD B 1YAIB_Photobacterium_leiognathi HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPwtDDnHkGD B 1YAIC_Photobacterium_leiognathi HQnGscaSsekdgkvvlggaAGgHYDPeHtnKHGfPwtDDnHkGD B Vibrio_alginolyticus HtnpscdSiekddktvlggaAGgHYDPnNtgKHGyPwtDDnHLGD B Vibrio_splendidus HanGscdSitkdgkiilggaAGgHYDPektgKHGfPwtDDnHLGD B Vibrio_vulnificus HanGsceSsnkdgkvvlggaAGgHYDPqNsgKHGyPwtEDnHLGD =============================================================================== Consensus HQFGDNTSGxxxxxxxxCTSAGPHFNPxNKxEHGxPEDEDRHVGD 230 240 250 260 270 ----|----:----|----:----|----:----|----:----| Consensus LGNLxxNxNGVAEiNIxDxLIsLsGxnSIIGRSMVVHexxDDLGR =============================================================================== * SCHISTOSOMA_MANSONI LGNVvagaDGnAvyNatDkLISLNGsHSIIGRSMVIHEneDDLGR * Schistosoma_japonicum LGNVvatdDGkgvyDatDkLISLSGpHSIIGRTMVIHEneDDLGR =============================================================================== * S_CEREVISIAE MGNVktDeNGVAKgSfkDsLIkLiGptSVVGRSVVIHagqDDLGK * 1B4TA_S_cerevisiae MGNVktDeNGVAKgSfkDsLIkLiGptSVVGRSVVIHagqDDLGK * 1F18A_S_cerevisiae MrNVktDeNGVAKgSfkDsLIkLiGptSVVGRSVVIHagqDDLGK * 1F1AA_S_cerevisiae MGNVktDeNGVAKgSfkDsLIkLiGptSVVGRSVVIHagqDDLGK * 1F1DA_S_cerevisiae MGNVktDeNGVAKgSfkDsLIkLiGptSVVGRSVVIHagqDDLGK * 1JK9C_S_cerevisiae MGNVktDeNGVAKgSfkDsLIkLiGptSVVGRSVVIHagqDDLGK * Aspergillus_flavus LGNfktDaeGnAvgSkqDkLIkLiGaeSVLGRTLVIHagtDDLGR * Aspergillus_fumigatus LGNfetDaeGnAvgSkqDkLIkLiGaeSVLGRTLVVHagtDDLGR * Candida_albicans LGNIstDgNGVAKgtkqDlLIkLiGkDSILGRTIVVHagtDDyGK * Candida_glabrata LGNIktDaqGVAKgvItDsLVkLiGptSVVGRSVVVHagtDDLGK * Chaetomium_globosum LGNIetDaqGnsKgtVtDkhIkIiGpeSVIGRTVVVHagtDDLGK * Chaetomium_thermophilum LGNIetDaNGnsKgtMtDhLVkLiGpeSVIGRTVVVHagtDDLGK * Coccidioides_immitis LGNIttDsqGnstgSVeDkqIkLiGeHSVLGRTIVVHagtDDLGK * Cryptococcus_neoformans LGNVktDgNGVAsVNIsDksLSLfGpySIIGRTIVVHagtDDfGK * Debaryomyces_hansenii LGNVttDtSGVAKgSkqDlfVkLiGqNSILGRTVVIHagtDDLGK * Emericella_nidulans LGNfktDaeGnsKgSktDkLIkLiGaeSVLGRTLVVHagtDDLGR * Eremothecium_gossypii MGNVlaDaNGVAvgSakDpLIkIfGptSILGRTVVVHagkDDLGR * Gibberella_zeae LGNVetDgqGnAKgSVtDsLIkLiGpHSVIGRTVVIHagtDDLGK * Kluyveromyces_lactis LGNIptDaqGIsKgSLtDkhIkLlGplSIVGRTVVVHagqDDLGK * Neurospora_crassa LGNIetDaqGnAKgtVtDnLVkLiGpeSVIGRTVVVHagtDDLGK * Schizosaccharomyces_pombe LGNLesDaqGniKttfsDsVISLfGaNSIIGRTIVIHageDDLGK * Yarrowia_lipolytica LGNVktDseGVAKgvLkDsLLkLTGdNSIVGRTVVIHggeDDLGK =============================================================================== * HUMAN LGNVtaDkDGVADVSIeDsVISLSGdHcIIGRTLVVHEkaDDLGK * X_LAEVIS LGNVtae-gGVAQfkItDsLISLkGpNSIIGRTaVVHEkaDDLGK * BOVINE LGNVtaDkNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * 1AZVA_Human LGNVtaDkDGVADVSIeDsVISLSGdHcIIGRTLVVHEkaDDLGK * 1FUNA_Human LGNVtaDkDGVADVSIeDsVISLSGdHSIIGRTLVVHEkaDDLGK * 1L3NA_Human LGNVtaDkDGVADVSIeDsVISLSGdHSIIGRTLVVHEkaDDLGK * 1N19A_Human LGNVtaDkDGVADVSIeDsVISLSGdHSIIGRTLVVHEkaDDLGK * 1PTZA_Human LGNVtaDkDGVADVSIeDsVISLSGdHSIIGRTLVVHEkaDDLGK * 1CB4A_Bovine LGNVtaDkNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * 1E9OA_Bovine LGNVtaDsNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * 1E9OB_Bovine LGNVtaDkNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * 1E9PA_Bovine LGNVtaDsNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * 1E9PB_Bovine LGNVtaDkNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * 3SODO_Bovine LGNVtaDkNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * Apis_mellifera LGNIeaDaSGVAnVNItDktIqLqGpHSVIGRTLVVHadpDDLGK * Canis_lupus LGNVtagkDGVAiVSIeDsLIaLSGdySIIGRTMVVHEkrDDLGK * Capra_hircus LGNVkaDkNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * Cavia_porcellus LGNVtagaDGVAnVSIeDsLISLSGaNSIIGRTMVVHEkpDDLGK * Cebus_apella LGNVtagkDGVAKVSIeDsVISLSGdHSIIGRTLVVHEkaDDLGK * Chelonia_mydas LGNViaNkeGVAEVcIkDsLISLTGsqSIIGRTMVVHEkeDDLGK * Danio_rerio LGNVtaDaSGVAKIeIeDaMLTLSGqHSIIGRTMVIHEkeDDLGK * Horse LGNVtaDeNGkADVDMkDsVISLSGkHSIIGRTMVVHEkqDDLGK * Chicken LGNVta-kgGVAEVeIeDsVISLTGpHcIIGRTMVVHaksDDLGR * Hylobates_lar LGNVtaDkDGVAKVSIeDsVISLSGdHSIIGRTLVVHEkaDDLGK * Ixodes_scapularis LGNViagdDGVAKVaItDsqISLSGpHSIIGRSVVIHadpDDLGK * Macaca_mulatta LGNVtagkDGVAKVSfeDsVISLSGdHSIIGRTLVVHEkaDDLGK * Monodelphis_domestica LGNVtaNkDGVAtVSIkDshIeLSGpmSIIGRTMVVHEkaDDLGK * Mouse LGNVtagkDGVAnVSIeDrVISLSGeHSIIGRTMVVHEkqDDLGK * Oncorhynchus_mykiss LGNVtagaDnVAKINIqDkMLTLTGpDSIIGRTMVIHEkaDDLGK * Rabbit LGNVtagsNGVADVlIeDsVISLSGdmSVIGRTLVVHEkeDDLGK * Ovis_aries LGNVkaDkNGVAiVDIvDpLISLSGeySIIGRTMVVHEkpDDLGR * Pongo_pygmaeus LGNVtaDkDGVAsVSIeDsVISLSGdHcIIGRTLVVHEkaDDLGK * Rat LGNVaagkDGVAnVSIeDrVISLSGeHSIIGRTMVVHEkqDDLGK * Pig LGNVtagkDGVAtVyIeDsVIaLSGdHSIIGRTMVVHEkpDDLGR * Tetraodon_nigroviridis LGNVtaeaDqIAKIDItDsVISLhGkfSIIGRTMVIHEkaDDLGK * X_tropicalis LGNVta-kDGVAEfkLtDsLISLkGnHSIIGRcaVVHEkeDDLGK * Cervus_elaphus-SODC LGNVtaDkNGVAKVDIvDsLISLSGeHSIIGRTMVVHEkpDDLGR * Cervus_elaphus-SODC_VAR LGNVtaDkNGVAKVDIvDsLISLSGeHSIIGRTMVVHEkpDDLGR * X_laevis-SODC1 LGNVtae-gGVAQfkftDpqISLkGerSIIGRTaVVHEkqDDLGK * X_laevis-SODC2 LGNVtae-gGVAQfkItDsLISLkGpNSIIGRTaVVHEkaDDLGK * Bovine-SODC_BOSMU LGNVtaDkNGVAvVDIvDsLISLSGeySIIGRTMVVHEkpDDLGR =============================================================================== B PHOTOBACTERIUM_LEIOGNATHI LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B 1IB5A_Photobacterium_leiognathi LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B 1IBBA_Photobacterium_leiognathi LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B 1IBDA_Photobacterium_leiognathi LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B 1IBFA_Photobacterium_leiognathi LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B 1IBHA_Photobacterium_leiognathi LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B 1YAIB_Photobacterium_leiognathi LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B 1YAIC_Photobacterium_leiognathi LpaLfvSaNGLAtnpVlaprL-tlk--eLkGhaIMIHaggDNhsd B Vibrio_alginolyticus LppLyvDmDGnAnqpVvaprL-kls--dLkGRaLMIHaggDNhsd B Vibrio_splendidus LppLyvNaHGVADqpVmaprV-tld--dVkGRaLMIHaggDNhsd B Vibrio_vulnificus LpaLfvDaSGnAsqpVlaprV-alk--dVqGRaLMIHagaDNhsd =============================================================================== Consensus LGNLxxNxNGVAEiNIxDxLIsLsGxnSIIGRSMVVHexxDDLGR 280 290 300 310 ----:----|----:----|----:----|----:----|----: Consensus GGNDESxKTGNAGxRLACGVIGIAKxxxx =============================================================== * SCHISTOSOMA_MANSONI GGHElSkvTGNAGgRLACGVVGLAae--- * Schistosoma_japonicum GGHDlSkvTGNAGgRVACGVIGLAad--- =============================================================== * S_CEREVISIAE GdtEESlKTGNAGpRpACGVIGLtn---- * 1B4TA_S_cerevisiae GdtEESlKTGNAGpRpACGVIGLtn---- * 1F18A_S_cerevisiae GdtEESlKTGNAGpRpACGVIGLtn---- * 1F1AA_S_cerevisiae GdtEESlKTGNAGpRpACGVIGLtn---- * 1F1DA_S_cerevisiae GdtEESlKTGNAGpRpACGVIGLtn---- * 1JK9C_S_cerevisiae GdtEESlKTGNAGpRpACGVIGLtn---- * Aspergillus_flavus seHpESkKTGNAGaRpACGVIGIAa---- * Aspergillus_fumigatus GGNEESkKTGNAGaRpACGVIGIAa---- * Candida_albicans GGfEDSktTGHAGaRpACGVIGLtQ---- * Candida_glabrata GGNEESlKTGNAGpRpACGVIGLtn---- * Chaetomium_globosum GGNEESlKTGNAGpRpACGVIGIsQ---- * Chaetomium_thermophilum GGNEESlKTGNAGpRpACGVIGIAQ---- * Coccidioides_immitis GGNEESkKTGNAGpRpACGVIGIAa---- * Cryptococcus_neoformans GGNaESlKTGNAGaRaACGVIGIsn---- * Debaryomyces_hansenii GGNaESkKTGNAGaRLACGVIGLtnkpns * Emericella_nidulans GdSEESkKTGNAGaRpACGVIGIAa---- * Eremothecium_gossypii GGNEESlKTGNAGpRpACGVIGIAn---- * Gibberella_zeae GdgEESlKTGNAGpRpACGMciLlyfpmv * Kluyveromyces_lactis GGDaESlKTGNAGaRhACGVIGIsn---- * Neurospora_crassa GGNEESlKTGNAGpRpACGVIGIsQ---- * Schizosaccharomyces_pombe GtSEESlKTGNAGaRnACGVIGIAv---- * Yarrowia_lipolytica GGHaDSlKTGNAGpRpACGVIGLta---- =============================================================== * HUMAN GGNEEStKTGNAGsRLACGVIGIAQ---- * X_LAEVIS GGNDESlKTGNAGgRLACGVIGysp---- * BOVINE GGNEEStKTGNAGsRLACGVIGIAK---- * 1AZVA_Human GGNEEStKTGNAGsRLACGVIGIAQ---- * 1FUNA_Human GGNEEStETGNAGsRLACGVIGIAQ---- * 1L3NA_Human GGNEEStKTGNAGsRLACGVIGIAQ---- * 1N19A_Human GGNEEStKTGNAGsRLACGVIGIAQ---- * 1PTZA_Human GGNEEStKTGNAGsRLACGVIGIAQ---- * 1CB4A_Bovine GGNEEStKTGNAGsRLACGVIGIAK---- * 1E9OA_Bovine GGNEEStKTGNAGsRLACGVIGIAK---- * 1E9OB_Bovine GGNEEStsTGNAGsRLACGVIGIAK---- * 1E9PA_Bovine GGNEEStKTGNAGsRLACGVIGIAs---- * 1E9PB_Bovine GGNEEStsTGNAGsRLACGVIGIAs---- * 3SODO_Bovine GGNEEStKTGNAGsRLACGVIGIAK---- * Apis_mellifera GGvElSktTGNAGaRLACGVIGItKv--- * Canis_lupus GdNEEStQTGNAGsRLACGVIGIAQ---- * Capra_hircus GGNEEStKTGNAGscLACGVIGIAp---- * Cavia_porcellus GGNEEStKTGNAGsRLACGVIGIAQ---- * Cebus_apella GGNEEStKTGNAGsRLACGVIGIAQ---- * Chelonia_mydas GGNDESlKTGNAGsRLACGVVGIAKl--- * Danio_rerio GGNEESlKTGNAGgRLACGVIGItQ---- * Horse GGNEEStKTGNAGsRLACGVIGIAp---- * Chicken GGDNESklTGNAGpRLACGVIGIAKc--- * Hylobates_lar GGNEEStKTGNAGsRLACGVIGIAQ---- * Ixodes_scapularis GGHElSktTGNAGaRLACGVVGVtK---- * Macaca_mulatta GGNEESkKTGNAGgRLACGVIGIAQ---- * Monodelphis_domestica GGNaESeKTGNAGpRLACGVIGIAK---- * Mouse GGNEEStKTGNAGsRLACGVIGIAQ---- * Oncorhynchus_mykiss GGNEESlKTGNAGgRqACGVIGIAQ---- * Rabbit GGNDEStKTGNAGsRLACGVIGIsp---- * Ovis_aries GGNEEStKTGNAGgRLACGVIGIAp---- * Pongo_pygmaeus GGNEEStKTGNAGsRLACGVIGIAQ---- * Rat GGNEEStKTGNAGsRLACGVIGIAQ---- * Pig GGNEEStKTGNAGsRLACGVIGItQ---- * Tetraodon_nigroviridis GGNEESlKTGNAGgRLACGVIGItQ---- * X_tropicalis GGNDESlKTGNAGgRLACGVIGLcQ---- * Cervus_elaphus-SODC GGNEEStKTGNArnRLACGVIGIAQ---- * Cervus_elaphus-SODC_VAR GGNEEStKTGNArnRLACGVIGIAQ---- * X_laevis-SODC1 GGDDESlKTGNAGgRLACGVIGfcp---- * X_laevis-SODC2 GGNDESlKTGNAGgRLACGVIGysp---- * Bovine-SODC_BOSMU GGNEEStKTGNAGsRLACGVIGIAK---- =============================================================== B PHOTOBACTERIUM_LEIOGNATHI m----pkalGggGaRVACGVI---Q---- B 1IB5A_Photobacterium_leiognathi m----pkalGggGaRVACGVI---Q---- B 1IBBA_Photobacterium_leiognathi m----pkalGggGaRVACGVI---Q---- B 1IBDA_Photobacterium_leiognathi m----pkalGggGaRVACGVI---Q---- B 1IBFA_Photobacterium_leiognathi m----pkalGggGaRVACGVI---Q---- B 1IBHA_Photobacterium_leiognathi m----pkalGggGaRVACGVI---Q---- B 1YAIB_Photobacterium_leiognathi m----pkalGggGaRVACGVI---Q---- B 1YAIC_Photobacterium_leiognathi m----pkalGggGaRVACGVI---Q---- B Vibrio_alginolyticus h----psKlGggGaRVvCGVI---E---- B Vibrio_splendidus h----paKlGggGaRIvCGVI---K---- B Vibrio_vulnificus h----pmplGggGaRIvCGVI---K---- =============================================================== Consensus GGNDESxKTGNAGxRLACGVIGIAKxxxx

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