10 20 30 40 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS ----------------------------------age--- A Archaeoglobus_fulgidus ---------------------------------------- A Pyrococcus_abyssi ------------------------mimgkks---sdp--- ============================================================================ A METHANOCOCCUS_VOLTAE -------------------------------sdn------ A Methanococcus_jannaschii itfiyffgniiyylpiysyinnykfmlmviimdd------ A Methanococcus_maripaludis -------------------------------adv------ ============================================================================ A SULFOLOBUS_SOLFATARICUS ----------------------------------sne--- A Desulfurococcus_amylolyticus ----------------------------------seeket A Sulfolobus_acidocaldarius ---------------------------------------- A Sulfolobus_tokodaii ----------------------------------ndm--- A Aeropyrum_pernix-RADA ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH3 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB6 ---------------------------------------- ============================================================================ * HUMAN ---------------------------------------- * S_CEREVISIAE ----------------------------------sqv--- * Apis_mellifera ---------------------------------------- * Aspergillus_flavus ---------------------------------------- * Aspergillus_fumigatus ---------------------------------------- * Bovine ---------------------------------------- * C_elegans -------------saqasrqkk--sdqeqra--------- * Candida_albicans ----------------------tqteie-qv---dlh-ee * Candida_glabrata ----------------------------------tev--- * Canis_lupus ---------------------------------------- * Chaetomium_globosum ---------------------------------------- * Coccidioides_immitis ---------------------------------------- * Coprinus_cinereus ---------------------------------------- * Cricetulus_griseus ---------------------------------------- * Cryptococcus_neoformans ---------------------------------------- * Danio_rerio ---------------------------------------- * Debaryomyces_hansenii -------------tet------------------------ * D_melanogaster ---------------------------------------- * D_pseudoobscura ---------------------------------------- * Emericella_nidulans ---------------------------------------- * Encephalitozoon_cuniculi ---------------------------------------- * Eremothecium_gossypii -sqvqehiiqdphssqynihatgaserqgss---eht-dg * Chicken ---------------------------------------- * Gibberella_zeae ---------------------------------------- * Kluyveromyces_lactis ---------------------------------------- * Mouse ---------------------------------------- * Neurospora_crassa ----------------sn---------------------- * Rabbit ---------------------------------------- * Pichia_angusta ---------------tqvaevnhitsneqqg---s----- * Rat ---------------------------------------- * Schizosaccharomyces_pombe --------------adtev-emqvsaadtnn---nen-gq * Strongylocentrotus_purpuratus ---------------------------------------- * Tetraodon_nigroviridis ---------------------------------------- * Tribolium_castaneum ---------------------------------------- * Ustilago_maydis ---------------------------------------- * X_tropicalis ---------------------------------------- * Yarrowia_lipolytica ---------------------------------------- * X_laevis-RA51A ---------------------------------------- * X_laevis-RA51B ---------------------------------------- Cryptosporidium_hominis --------------stin---------------------- Cryptosporidium_parvum --------------stin---------------------- Dictyostelium_discoideum -------------asrqrqe-------------------- Entamoeba_histolytica ---------sakqiqrgseeelleseenlke---ke---- Leishmania_donovani qtrskakgrrgrpsarpsdevevvesqpqea---lqn-ee Leishmania_tropica qtrskakgrrgrpsarpseevevvesqpqev---lqn-ee Plasmodium_berghei -------------------------pamksa---n----- Plasmodium_falciparum ---------------------------------------- Tetrahymena_thermophila ---------------------------------------- Theileria_annulata -------------------------ssd------------ Theileria_parva -------------------------ssd------------ Trypanosoma_brucei ------------ntrtknkkrtkeviedevh---did-dt Trypanosoma_cruzi -------ntrskrgkrkgveevevheiants---pdp-va P Arabidopsis_thaliana ---------------------------------------- P Oryza_sativa ---------------------------------------- P Maize-R51A1 ---------------------------------------- P Maize-R51A2 ---------------------------------------- ============================================================================ B E_COLI ----------------------------------ai---- B MYCOBACTERIUM_SMEGMATIS ----------------------------------aqq--- B MYCOBACTERIUM_TUBERCULOSIS ----------------------------------tq---- B Acinetobacter_calcoaceticus ---------------------------------------- B Actinobacillus_pleuropneumoniae -----asdnkkaqkntvtk---------------qi---- B Actinobacillus_succinogenes -----atpndktk---------------------ps---- B Actinomyces_bovis ----------------------------------apq--- B Azotobacter_vinelandii ---------------------------------------- B Bacillus_clausii ---------------------------------------- B Bacillus_halodurans ---------------------------------------- B Bacillus_licheniformis ---------------------------------------- B Bacillus_megaterium ---------------------------------------- B Bacillus_subtilis ---------------------------------------- B Bordetella_pertussis -----ddktsk-----------------------aa---- B Burkholderia_fungorum -----eeskkgsa---------------------gl---- B Chromobacterium_violaceum -----------------------------------a---- B Clostridium_acetobutylicum ---------------------------------------- B Clostridium_thermocellum -----------------------------------i---- B Colwellia_psychrerythraea ---------------------------------------- B Corynebacterium_efficiens -----atkkttkaa--------------------pk---- B Desulfotalea_psychrophila -----v----------------------------gat--- B Enterococcus_faecalis ---------------------------------------- B Haemophilus_ducreyi -----aadkkaqkntatk----------------qi---- B Haemophilus_influenzae ----------------------------------at---- B Histophilus_somni ----------------------------------at---- B Kineococcus_radiotolerans ----------------------------------pa---- B Leifsonia_xyli -----------------------------------ps--- B Mannheimia_succiniciproducens ----------------------------------at---- B Nitrosomonas_europaea ---------------------------------------- B Nitrosomonas_eutropha ---------------------------------------- B Oceanobacillus_iheyensis ---------------------------------------- B Pasteurella_multocida ----------------------------------at---- B Photobacterium_profundum ---------------------------------------- B Photorhabdus_luminescens ----------------------------------ai---- B Proteus_mirabilis ----------------------------------ai---- B Pseudomonas_cepacia ---------------------------------------- B Pseudomonas_pseudomallei -----eeskkgs----------------------gl---- B Shewanella_amazonensis -----------------------------------ki--- B Shewanella_putrefaciens ----------------------------------kv---- B Streptomyces_avermitilis -----------------------------------a---- B Vibrio_alginolyticus ---------------------------------------- B Vibrio_angustum ---------------------------------------- B Vibrio_cholerae ---------------------------------------- B Vibrio_fischeri ---------------------------------------- B Vibrio_parahaemolyticus ---------------------------------------- B Vibrio_splendidus ---------------------------------------- B Vibrio_vulnificus ---------------------------------------- B Yersinia_enterocolitica ----------------------------------ai---- B Cupriavidus_metallidurans-Q1LR74 -----ddkkaga----------------------gv---- B Cupriavidus_metallidurans-RECA -----ddkkaga----------------------gv---- B Erwinia_carotovora-RECA -----------------------------------ai--- B Erwinia_carotovora-RECA_ERWCT -----------------------------------ai--- B Listeria_monocytogenes-RECA ---------------------------------------- B Listeria_monocytogenes-RECA_LISMF ---------------------------------------- B Neisseria_gonorrhoeae-RECA ---------------------------------------- B Neisseria_gonorrhoeae-RECA_VAR ---------------------------------------- B Salmonella_typhi-RECA ----------------------------------ai---- B Salmonella_typhi-RECA_SALPA ----------------------------------ai---- B Streptomyces_coelicolor-RECA -----------------------------------a---- B Streptomyces_coelicolor-RECA_STRL -----------------------------------a---- B Xylella_fastidiosa-RECA ---------------------------------------- B Xylella_fastidiosa-RECA_XYLFT ---------------------------------------- B Yersinia_pestis-RECA ----------------------------------ai---- B Yersinia_pestis-RECA_YERPS ----------------------------------ai---- B Mycobacterium_tuberculosis-RECA ----------------------------------tq---- B Mycobacterium_tuberculosis-RECA_M ----------------------------------tq---- B Neisseria_meningitidis-RECA ---------------------------------------- B Neisseria_meningitidis-RECA_NEIMA ---------------------------------------- B Neisseria_meningitidis-RECA_VAR ---------------------------------------- B Xanthomonas_vasicola-RECA_XANAC -----svspavsacaihrryispipksltri---tqm--- B Xanthomonas_vasicola-RECA_XANCP -----svspavsacaihrryispipksltri---tqm--- B Xanthomonas_vasicola-YP_201580 -----svspavsacaihrryispipksltri---tqm--- B Pseudomonas_aeruginosa-Q48F94 ---------------------------------------- B Pseudomonas_aeruginosa-RECA ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEF5 ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEFL ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPK ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPU ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSESM ---------------------------------------- ============================================================================ B DEINOCOCCUS_RADIODURANS ----------------------------------gsh--- B Deinococcus_geothermalis ---------------------------------------- B Thermus_aquaticus-RECA ---------------------------------------- B Thermus_aquaticus-RECA_THET2 ---------------------------------------- B Thermus_aquaticus-RECA_THET8 ---------------------------------------- B Thermus_aquaticus-RECA_THETH ---------------------------------------- ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 50 60 70 80 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS -----evke--idefeelgf-e-pateetpkkkkke---- A Archaeoglobus_fulgidus -------------------s-e-esneet----------- A Pyrococcus_abyssi -----avve--indvdelel-e-vgeevtskkkkke---- ============================================================================ A METHANOCOCCUS_VOLTAE ---------------------------------------- A Methanococcus_jannaschii ---------------------------------------- A Methanococcus_maripaludis ---------------------------------------- ============================================================================ A SULFOLOBUS_SOLFATARICUS -veqk-----k----------------------------- A Desulfurococcus_amylolyticus ikers-----s----------------------------- A Sulfolobus_acidocaldarius -sndg-----k----------------------------- A Sulfolobus_tokodaii -ssdg-----k----------------------------- A Aeropyrum_pernix-RADA -gedk-----r----------------------------- A Aeropyrum_pernix-RADA_VAR_OH1 -gedk-----r----------------------------- A Aeropyrum_pernix-RADA_VAR_OH2 -gedk-----r----------------------------- A Aeropyrum_pernix-RADA_VAR_OH3 -gedk-----r----------------------------- A Aeropyrum_pernix-RADA_VAR_TB1 -gedq-----r----------------------------- A Aeropyrum_pernix-RADA_VAR_TB2 -gedn-----r----------------------------- A Aeropyrum_pernix-RADA_VAR_TB6 -gedk-----r----------------------------- ============================================================================ * HUMAN ---------------------------------------- * S_CEREVISIAE -----qeqh--isesqlqy-g-ngslmstvpadlsqsvvd * Apis_mellifera ---------------------------------------- * Aspergillus_flavus ---------------------------------------- * Aspergillus_fumigatus ---------------------------------------- * Bovine ---------------------------------------- * C_elegans ---------------------------------------- * Candida_albicans g--------------------------------------- * Candida_glabrata -----hedhg-vpdsqv-n----vspistapaettqs--- * Canis_lupus ---------------------------------------- * Chaetomium_globosum ---------------------------------------- * Coccidioides_immitis ---------------------------------------- * Coprinus_cinereus ---------------------------------------- * Cricetulus_griseus ---------------------------------------- * Cryptococcus_neoformans ---------------------------------------- * Danio_rerio ---------------------------------------- * Debaryomyces_hansenii ---------------------------------------- * D_melanogaster ---------------------------------------- * D_pseudoobscura ---------------------------------------- * Emericella_nidulans ---------------------------------------- * Encephalitozoon_cuniculi ---------------------------------------- * Eremothecium_gossypii d--------------------------------------- * Chicken ---------------------------------------- * Gibberella_zeae ---------------------------------------- * Kluyveromyces_lactis -------sq--veevqttq-g-hsqlmvsr---------- * Mouse ---------------------------------------- * Neurospora_crassa ---------------------------------------- * Rabbit ---------------------------------------- * Pichia_angusta ---------------------------------------- * Rat ---------------------------------------- * Schizosaccharomyces_pombe a--------------------------------------- * Strongylocentrotus_purpuratus ---------------------------------------- * Tetraodon_nigroviridis ---------------------------------------- * Tribolium_castaneum ---------------------------------------- * Ustilago_maydis ---------------------------------------- * X_tropicalis ---------------------------------------- * Yarrowia_lipolytica ---------------------------------------- * X_laevis-RA51A ---------------------------------------- * X_laevis-RA51B ---------------------------------------- Cryptosporidium_hominis ---------------------------------------- Cryptosporidium_parvum ---------------------------------------- Dictyostelium_discoideum ---------------------------------------- Entamoeba_histolytica ---------------------------------------- Leishmania_donovani q--------------------------------------- Leishmania_tropica q--------------------------------------- Plasmodium_berghei ---------------------------------------- Plasmodium_falciparum ---------------------------------------- Tetrahymena_thermophila ---------------------------------------- Theileria_annulata ---------------------------------------- Theileria_parva ---------------------------------------- Trypanosoma_brucei a--------------------------------------- Trypanosoma_cruzi a--------------------------------------- P Arabidopsis_thaliana ---------------------------------------- P Oryza_sativa ---------------------------------------- P Maize-R51A1 ---------------------------------------- P Maize-R51A2 ---------------------------------------- ============================================================================ B E_COLI ---------------------------------------- B MYCOBACTERIUM_SMEGMATIS ---------------------------------------- B MYCOBACTERIUM_TUBERCULOSIS ---------------------------------------- B Acinetobacter_calcoaceticus ---------------------------------------- B Actinobacillus_pleuropneumoniae ---------------------------------------- B Actinobacillus_succinogenes ---------------------------------------- B Actinomyces_bovis ---------------------------------------- B Azotobacter_vinelandii ---------------------------------------- B Bacillus_clausii ---------------------------------------- B Bacillus_halodurans ---------------------------------------- B Bacillus_licheniformis ---------------------------------------- B Bacillus_megaterium ---------------------------------------- B Bacillus_subtilis ---------------------------------------- B Bordetella_pertussis ---------------------------------------- B Burkholderia_fungorum ---------------------------------------- B Chromobacterium_violaceum ---------------------------------------- B Clostridium_acetobutylicum ---------------------------------------- B Clostridium_thermocellum ---------------------------------------- B Colwellia_psychrerythraea ---------------------------------------- B Corynebacterium_efficiens ---------------------------------------- B Desulfotalea_psychrophila ---------------------------------------- B Enterococcus_faecalis ---------------------------------------- B Haemophilus_ducreyi ---------------------------------------- B Haemophilus_influenzae ---------------------------------------- B Histophilus_somni ---------------------------------------- B Kineococcus_radiotolerans ---------------------------------------- B Leifsonia_xyli ---------------------------------------- B Mannheimia_succiniciproducens ---------------------------------------- B Nitrosomonas_europaea ---------------------------------------- B Nitrosomonas_eutropha ---------------------------------------- B Oceanobacillus_iheyensis ---------------------------------------- B Pasteurella_multocida ---------------------------------------- B Photobacterium_profundum ---------------------------------------- B Photorhabdus_luminescens ---------------------------------------- B Proteus_mirabilis ---------------------------------------- B Pseudomonas_cepacia ---------------------------------------- B Pseudomonas_pseudomallei ---------------------------------------- B Shewanella_amazonensis ---------------------------------------- B Shewanella_putrefaciens ---------------------------------------- B Streptomyces_avermitilis ---------------------------------------- B Vibrio_alginolyticus ---------------------------------------- B Vibrio_angustum ---------------------------------------- B Vibrio_cholerae ---------------------------------------- B Vibrio_fischeri ---------------------------------------- B Vibrio_parahaemolyticus ---------------------------------------- B Vibrio_splendidus ---------------------------------------- B Vibrio_vulnificus ---------------------------------------- B Yersinia_enterocolitica ---------------------------------------- B Cupriavidus_metallidurans-Q1LR74 ---------------------------------------- B Cupriavidus_metallidurans-RECA ---------------------------------------- B Erwinia_carotovora-RECA ---------------------------------------- B Erwinia_carotovora-RECA_ERWCT ---------------------------------------- B Listeria_monocytogenes-RECA ---------------------------------------- B Listeria_monocytogenes-RECA_LISMF ---------------------------------------- B Neisseria_gonorrhoeae-RECA ---------------------------------------- B Neisseria_gonorrhoeae-RECA_VAR ---------------------------------------- B Salmonella_typhi-RECA ---------------------------------------- B Salmonella_typhi-RECA_SALPA ---------------------------------------- B Streptomyces_coelicolor-RECA ---------------------------------------- B Streptomyces_coelicolor-RECA_STRL ---------------------------------------- B Xylella_fastidiosa-RECA ---------------------------------------- B Xylella_fastidiosa-RECA_XYLFT ---------------------------------------- B Yersinia_pestis-RECA ---------------------------------------- B Yersinia_pestis-RECA_YERPS ---------------------------------------- B Mycobacterium_tuberculosis-RECA ---------------------------------------- B Mycobacterium_tuberculosis-RECA_M ---------------------------------------- B Neisseria_meningitidis-RECA ---------------------------------------- B Neisseria_meningitidis-RECA_NEIMA ---------------------------------------- B Neisseria_meningitidis-RECA_VAR ---------------------------------------- B Xanthomonas_vasicola-RECA_XANAC ---------------------------------------- B Xanthomonas_vasicola-RECA_XANCP ---------------------------------------- B Xanthomonas_vasicola-YP_201580 ---------------------------------------- B Pseudomonas_aeruginosa-Q48F94 ---------------------------------------- B Pseudomonas_aeruginosa-RECA ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEF5 ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEFL ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPK ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPU ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSESM ---------------------------------------- ============================================================================ B DEINOCOCCUS_RADIODURANS -----mskd--atkeisap-t-d----------------- B Deinococcus_geothermalis ------skd--npkdfgtp-s-d----------------- B Thermus_aquaticus-RECA ---------------------------------------- B Thermus_aquaticus-RECA_THET2 ---------------------------------------- B Thermus_aquaticus-RECA_THET8 ---------------------------------------- B Thermus_aquaticus-RECA_THETH ---------------------------------------- ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 90 100 110 120 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxdxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS --------------------kii-r-si------------ A Archaeoglobus_fulgidus --------------------kii---el------------ A Pyrococcus_abyssi --------------------kei-r-ti------------ ============================================================================ A METHANOCOCCUS_VOLTAE -----------------------l--td------------ A Methanococcus_jannaschii -----------------------l--tq------------ A Methanococcus_maripaludis -----------------------l--te------------ ============================================================================ A SULFOLOBUS_SOLFATARICUS -----------------------n--ik------------ A Desulfurococcus_amylolyticus -----------------------g--fi------------ A Sulfolobus_acidocaldarius -----------------------k--vk------------ A Sulfolobus_tokodaii -----------------------k--vk------------ A Aeropyrum_pernix-RADA -----------------------e--ik------------ A Aeropyrum_pernix-RADA_VAR_OH1 -----------------------e--ik------------ A Aeropyrum_pernix-RADA_VAR_OH2 -----------------------e--ik------------ A Aeropyrum_pernix-RADA_VAR_OH3 -----------------------e--ik------------ A Aeropyrum_pernix-RADA_VAR_TB1 -----------------------e--ik------------ A Aeropyrum_pernix-RADA_VAR_TB2 -----------------------e--ik------------ A Aeropyrum_pernix-RADA_VAR_TB6 -----------------------e--ik------------ ============================================================================ * HUMAN ------------------------a---mqmql-ean-a- * S_CEREVISIAE gngngssedieatngsgdgg----g---lqeqa-eaq-ge * Apis_mellifera -------------------s----a---masta-slq-gd * Aspergillus_flavus ------------------------t---aDmdt-qne-y- * Aspergillus_fumigatus ------------------------t---aDlet-qne-y- * Bovine ------------------------a---mqmql-ean-a- * C_elegans ------------------------a---dqall-naa-i- * Candida_albicans ------------------------s---hpqni-nad-a- * Candida_glabrata -----------stnrsmdynsge-q---lfhqe-qye-eg * Canis_lupus ------------------------a---mqmql-ean-a- * Chaetomium_globosum ------------------------a---gheeydesg-s- * Coccidioides_immitis ------------------------g---aEael-dgy-e- * Coprinus_cinereus ------------------------s---qgydg-sqi-p- * Cricetulus_griseus ------------------------a---mqmql-ean-a- * Cryptococcus_neoformans ------------sreqeqdp----f---vNqhg-e----e * Danio_rerio -----------------------------amrn-asr-ve * Debaryomyces_hansenii ------------------------e---gaqtn-ehe-a- * D_melanogaster -----------------------------Eklt-nvq-aq * D_pseudoobscura -----------------------------------da-l- * Emericella_nidulans ------------------------t---aDmet-qne-f- * Encephalitozoon_cuniculi ------------------------s---eEyqy-q----- * Eremothecium_gossypii ------------------------v---iEvha-esg-r- * Chicken ------------------------a---mqvqf-eas-t- * Gibberella_zeae ------------------------s---qEhde-sqm-g- * Kluyveromyces_lactis -----teeqme-------------d---vqqri-qet-df * Mouse ------------------------a---mqmql-eas-a- * Neurospora_crassa ------------------------n---eEyde-sanme- * Rabbit ------------------------a---mqmql-ean-a- * Pichia_angusta ------------------------v---gEqel-sag-y- * Rat ------------------------a---mqmql-ean-a- * Schizosaccharomyces_pombe ------------------------q---sNyey-dvn-v- * Strongylocentrotus_purpuratus ------------------------a---mqmh----n-a- * Tetraodon_nigroviridis ------------------------a---maaev-rgq-a- * Tribolium_castaneum --------------------------------e-asl-as * Ustilago_maydis ------------------------s---qNaqd-paq-i- * X_tropicalis ------------------------a---mqahy-eae-a- * Yarrowia_lipolytica ---------------------------------------- * X_laevis-RA51A ------------------------a---mqahy-eae-a- * X_laevis-RA51B ------------------------a---mqahy-qae-a- Cryptosporidium_hominis ------------------------p---nEvvn-enn-e- Cryptosporidium_parvum ------------------------p---nEivn-enn-e- Dictyostelium_discoideum ------------------------e---eEvdi-ene-q- Entamoeba_histolytica ------------------------k---vNeee-hee-e- Leishmania_donovani ------------------------e---pqqpq-qqq-s- Leishmania_tropica ------------------------e---pqqqq-qqq-s- Plasmodium_berghei ------------------------a---kEdti-sqt-c- Plasmodium_falciparum ----------kqantkedks----q---kisns-sti-de Tetrahymena_thermophila -----------------------------------ae-y- Theileria_annulata ------------------------e---lslvk-een-s- Theileria_parva ------------------------e---lslvk-een-s- Trypanosoma_brucei ------------------------f---dDaav-dav-n- Trypanosoma_cruzi ------------------------p---eqqqq-qqe-d- P Arabidopsis_thaliana ------------------------t---tmeqr-rnq-na P Oryza_sativa ------------------------s---tsaaa-aaa-a- P Maize-R51A1 -----------------ssa----a---qqqqk-aaa-ae P Maize-R51A2 -----------------sss----s---ahqka-spp-ie ============================================================================ B E_COLI ------------------------d---eN---------- B MYCOBACTERIUM_SMEGMATIS ------------------------a---pD---------- B MYCOBACTERIUM_TUBERCULOSIS ------------------------a---pD---------- B Acinetobacter_calcoaceticus ------------------------d---dN---------- B Actinobacillus_pleuropneumoniae ------------------------dp--eq---------- B Actinobacillus_succinogenes ------------------------a---eE---------- B Actinomyces_bovis ------------------------a---yD---------- B Azotobacter_vinelandii ------------------------d---eN---------- B Bacillus_clausii ----------------------------sD---------- B Bacillus_halodurans ----------------------------sD---------- B Bacillus_licheniformis ----------------------------sD---------- B Bacillus_megaterium ----------------------------nD---------- B Bacillus_subtilis ----------------------------sD---------- B Bordetella_pertussis ------------------------a---aE---------- B Burkholderia_fungorum ------------------------t---aE---------- B Chromobacterium_violaceum ------------------------s---eD---------- B Clostridium_acetobutylicum ------------------------d---nE---------- B Clostridium_thermocellum ------------------------e--------------- B Colwellia_psychrerythraea ------------------------k---dD---------- B Corynebacterium_efficiens ------------------------g---dD---------- B Desulfotalea_psychrophila ------------------------a---kD---------- B Enterococcus_faecalis ------------------------a---bD---------- B Haemophilus_ducreyi ------------------------dp--eq---------- B Haemophilus_influenzae ------------------------q---eE---------- B Histophilus_somni ------------------------p---eE---------- B Kineococcus_radiotolerans ------------------------p---aD---------- B Leifsonia_xyli ------------------------p---aD---------- B Mannheimia_succiniciproducens ------------------------n---dE---------- B Nitrosomonas_europaea ------------------------d---eN---------- B Nitrosomonas_eutropha ------------------------d---eN---------- B Oceanobacillus_iheyensis ----------------------------sD---------- B Pasteurella_multocida ------------------------k---eE---------- B Photobacterium_profundum ------------------------d---dN---------- B Photorhabdus_luminescens ------------------------d---eN---------- B Proteus_mirabilis ------------------------d---eN---------- B Pseudomonas_cepacia ------------------------t---aE---------- B Pseudomonas_pseudomallei ------------------------t---aE---------- B Shewanella_amazonensis ------------------------d---pN---------- B Shewanella_putrefaciens ------------------------d---pN---------- B Streptomyces_avermitilis ------------------------g---tD---------- B Vibrio_alginolyticus ------------------------d---eN---------- B Vibrio_angustum ------------------------d---dN---------- B Vibrio_cholerae ------------------------d---eN---------- B Vibrio_fischeri ------------------------d---dN---------- B Vibrio_parahaemolyticus ------------------------d---eN---------- B Vibrio_splendidus ------------------------d---eN---------- B Vibrio_vulnificus ------------------------d---eN---------- B Yersinia_enterocolitica ------------------------d---eN---------- B Cupriavidus_metallidurans-Q1LR74 ------------------------s---aE---------- B Cupriavidus_metallidurans-RECA ------------------------s---aE---------- B Erwinia_carotovora-RECA ------------------------d---eN---------- B Erwinia_carotovora-RECA_ERWCT ------------------------d---eN---------- B Listeria_monocytogenes-RECA ----------------------------nD---------- B Listeria_monocytogenes-RECA_LISMF ----------------------------nD---------- B Neisseria_gonorrhoeae-RECA ------------------------s---dD---------- B Neisseria_gonorrhoeae-RECA_VAR ------------------------s---dD---------- B Salmonella_typhi-RECA ------------------------d---eN---------- B Salmonella_typhi-RECA_SALPA ------------------------d---eN---------- B Streptomyces_coelicolor-RECA ------------------------g---tD---------- B Streptomyces_coelicolor-RECA_STRL ------------------------g---tD---------- B Xylella_fastidiosa-RECA ------------------------d---eN---------- B Xylella_fastidiosa-RECA_XYLFT ------------------------d---eN---------- B Yersinia_pestis-RECA ------------------------d---eN---------- B Yersinia_pestis-RECA_YERPS ------------------------d---eN---------- B Mycobacterium_tuberculosis-RECA ------------------------t---pD---------- B Mycobacterium_tuberculosis-RECA_M ------------------------a---pD---------- B Neisseria_meningitidis-RECA ------------------------s---dD---------- B Neisseria_meningitidis-RECA_NEIMA ------------------------s---dD---------- B Neisseria_meningitidis-RECA_VAR ------------------------s---dD---------- B Xanthomonas_vasicola-RECA_XANAC ------------------------d---eN---------- B Xanthomonas_vasicola-RECA_XANCP ------------------------d---eN---------- B Xanthomonas_vasicola-YP_201580 ------------------------d---eN---------- B Pseudomonas_aeruginosa-Q48F94 ------------------------d---dN---------- B Pseudomonas_aeruginosa-RECA ------------------------d---eN---------- B Pseudomonas_aeruginosa-RECA_PSEF5 ------------------------d---dN---------- B Pseudomonas_aeruginosa-RECA_PSEFL ------------------------d---dN---------- B Pseudomonas_aeruginosa-RECA_PSEPK ------------------------d---dN---------- B Pseudomonas_aeruginosa-RECA_PSEPU ------------------------d---dN---------- B Pseudomonas_aeruginosa-RECA_PSESM ------------------------d---dN---------- ============================================================================ B DEINOCOCCUS_RADIODURANS -----------------------a--ke------------ B Deinococcus_geothermalis -----------------------s--ke------------ B Thermus_aquaticus-RECA -----------------------e--en------------ B Thermus_aquaticus-RECA_THET2 -----------------------d--es------------ B Thermus_aquaticus-RECA_THET8 -----------------------d--es------------ B Thermus_aquaticus-RECA_THETH -----------------------d--es------------ ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxdxxxxxxxxxx 130 140 150 160 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS ---------------------------------------- A Archaeoglobus_fulgidus ---------------------------------------- A Pyrococcus_abyssi ---------------------------------------- ============================================================================ A METHANOCOCCUS_VOLTAE ---------------------------------------- A Methanococcus_jannaschii ---------------------------------------- A Methanococcus_maripaludis ---------------------------------------- ============================================================================ A SULFOLOBUS_SOLFATARICUS ---------------------------------------- A Desulfurococcus_amylolyticus ---------------------------------------- A Sulfolobus_acidocaldarius ---------------------------------------- A Sulfolobus_tokodaii ---------------------------------------- A Aeropyrum_pernix-RADA ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH3 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB6 ---------------------------------------- ============================================================================ * HUMAN --dts------v-----eee-----s---f--g-p--q-- * S_CEREVISIAE medea------y-----dea-----a---l--g-sf-v-- * Apis_mellifera eefee------y-----npq-----a-----------k-- * Aspergillus_flavus --dds------g-----lpg-----p---g--a-p--t-- * Aspergillus_fumigatus --des------g-----lpg-----p---g--a-p--t-- * Bovine --dts------v-----eee-----s---f--g-p--q-- * C_elegans --edn------a-----meq-----d---e--n-f--t-- * Candida_albicans --eve------a-----eed-----edvln--g-p--l-- * Candida_glabrata me---------------eda-----a---l--a-sf-v-- * Canis_lupus --dts------v-----eee-----s---f--g-p--q-- * Chaetomium_globosum --aed------v-----gqt-----g---p--gap--t-- * Coccidioides_immitis --dgd------c-----hap-----g------a-p--t-- * Coprinus_cinereus --egd------e-----edy-----q---f-sg-p--l-- * Cricetulus_griseus --dts------v-----eee-----s---f--g-p--q-- * Cryptococcus_neoformans aeeed------f-----e-------s---l--a-pm-l-- * Danio_rerio veaev------e-----eee-----n---f--g-p--q-- * Debaryomyces_hansenii --smg------d-----eed-----g---ls-g-p--l-- * D_melanogaster qeeee------------eeg-----p---l---------- * D_pseudoobscura --tns------v-----eee-----e---n--g-p--l-- * Emericella_nidulans --dds------g-----lpg-----p---g--a-p--t-- * Encephalitozoon_cuniculi --dte------y-----hse-----s---i---------- * Eremothecium_gossypii --gqg------y-----eed-----v---a--l-a--af- * Chicken --dts------a-----eee-----s---f--g-p--e-- * Gibberella_zeae --eeg------g-----mpg-----p---g--a-p--t-- * Kluyveromyces_lactis maee-------------ddv-----a---l--a-af-v-- * Mouse --dts------v-----eee-----s---f--g-p--q-- * Neurospora_crassa --dds------g-----ipn-----p---g--a-p--t-- * Rabbit --dts------v-----eee-----s---f--g-p--q-- * Pichia_angusta --hes------mvaeddedy-----s---a--g-p--v-- * Rat --dts------v-----eee-----s---f--g-p--q-- * Schizosaccharomyces_pombe --qde------e-----dea-----a---a--g-p--m-- * Strongylocentrotus_purpuratus --eqe------v-----see---------f--g-p--l-- * Tetraodon_nigroviridis --eve------------eee-----n---f--g-p--q-- * Tribolium_castaneum tdtvv------e-----dea-----k---n--g-gp-q-- * Ustilago_maydis --ged------d-----mge-----a---f--g-p--l-- * X_tropicalis -----------t-----eee-----n---f--g-p--q-- * Yarrowia_lipolytica ----a------d-----eei-----e---r--a-ga-i-- * X_laevis-RA51A -----------t-----eee-----h---f--g-p--q-- * X_laevis-RA51B -----------t-----eee-----n---f--g-p--q-- Cryptosporidium_hominis --nqn------n-----lne-----t---vyng-p--l-- Cryptosporidium_parvum --nqn------n-----lne-----t---vyng-p--l-- Dictyostelium_discoideum --qqe------e-----eee-----e---e--e-e--esy Entamoeba_histolytica --eee------e-----eee-----e---n--a-a--v-- Leishmania_donovani --tdm------a-----epn-----a---s--g-f--r-- Leishmania_tropica --tdm------a-----epn-----a---s--g-f--r-- Plasmodium_berghei --dns------t-----tedvdehly---t--g-p--l-- Plasmodium_falciparum ieeeq------l-----ytg-----p---l---------- Tetrahymena_thermophila --aed------v-----eqs-----d------g-p--m-- Theileria_annulata --mgv------s-----esg-----s---q--n-p--q-- Theileria_parva --mgv------s-----etg-----s---q--n-p--q-- Trypanosoma_brucei --dntqemqqqv-----gda-----a---g--g-psfr-- Trypanosoma_cruzi --qqn------v-----dga-----n---n--g-g-fr-- P Arabidopsis_thaliana vqqqd------d-----eet-----q---h--g-pf---- P Oryza_sativa --eqq------q-----eeg-----e---h--g-p--f-- P Maize-R51A1 qe----------------ev-----e---h--g-pf---- P Maize-R51A2 ee----------------at-----e---h--g-pf---- ============================================================================ B E_COLI ---------------------------------------- B MYCOBACTERIUM_SMEGMATIS ---------------------------------------- B MYCOBACTERIUM_TUBERCULOSIS ---------------------------------------- B Acinetobacter_calcoaceticus ---------------------------------------- B Actinobacillus_pleuropneumoniae ---------------------------------------- B Actinobacillus_succinogenes ---------------------------------------- B Actinomyces_bovis ---------------------------------------- B Azotobacter_vinelandii ---------------------------------------- B Bacillus_clausii ---------------------------------------- B Bacillus_halodurans ---------------------------------------- B Bacillus_licheniformis ---------------------------------------- B Bacillus_megaterium ---------------------------------------- B Bacillus_subtilis ---------------------------------------- B Bordetella_pertussis ---------------------------------------- B Burkholderia_fungorum ---------------------------------------- B Chromobacterium_violaceum ---------------------------------------- B Clostridium_acetobutylicum ---------------------------------------- B Clostridium_thermocellum ---------------------------------------- B Colwellia_psychrerythraea ---------------------------------------- B Corynebacterium_efficiens ---------------------------------------- B Desulfotalea_psychrophila ---------------------------------------- B Enterococcus_faecalis ---------------------------------------- B Haemophilus_ducreyi ---------------------------------------- B Haemophilus_influenzae ---------------------------------------- B Histophilus_somni ---------------------------------------- B Kineococcus_radiotolerans ---------------------------------------- B Leifsonia_xyli ---------------------------------------- B Mannheimia_succiniciproducens ---------------------------------------- B Nitrosomonas_europaea ---------------------------------------- B Nitrosomonas_eutropha ---------------------------------------- B Oceanobacillus_iheyensis ---------------------------------------- B Pasteurella_multocida ---------------------------------------- B Photobacterium_profundum ---------------------------------------- B Photorhabdus_luminescens ---------------------------------------- B Proteus_mirabilis ---------------------------------------- B Pseudomonas_cepacia ---------------------------------------- B Pseudomonas_pseudomallei ---------------------------------------- B Shewanella_amazonensis ---------------------------------------- B Shewanella_putrefaciens ---------------------------------------- B Streptomyces_avermitilis ---------------------------------------- B Vibrio_alginolyticus ---------------------------------------- B Vibrio_angustum ---------------------------------------- B Vibrio_cholerae ---------------------------------------- B Vibrio_fischeri ---------------------------------------- B Vibrio_parahaemolyticus ---------------------------------------- B Vibrio_splendidus ---------------------------------------- B Vibrio_vulnificus ---------------------------------------- B Yersinia_enterocolitica ---------------------------------------- B Cupriavidus_metallidurans-Q1LR74 ---------------------------------------- B Cupriavidus_metallidurans-RECA ---------------------------------------- B Erwinia_carotovora-RECA ---------------------------------------- B Erwinia_carotovora-RECA_ERWCT ---------------------------------------- B Listeria_monocytogenes-RECA ---------------------------------------- B Listeria_monocytogenes-RECA_LISMF ---------------------------------------- B Neisseria_gonorrhoeae-RECA ---------------------------------------- B Neisseria_gonorrhoeae-RECA_VAR ---------------------------------------- B Salmonella_typhi-RECA ---------------------------------------- B Salmonella_typhi-RECA_SALPA ---------------------------------------- B Streptomyces_coelicolor-RECA ---------------------------------------- B Streptomyces_coelicolor-RECA_STRL ---------------------------------------- B Xylella_fastidiosa-RECA ---------------------------------------- B Xylella_fastidiosa-RECA_XYLFT ---------------------------------------- B Yersinia_pestis-RECA ---------------------------------------- B Yersinia_pestis-RECA_YERPS ---------------------------------------- B Mycobacterium_tuberculosis-RECA ---------------------------------------- B Mycobacterium_tuberculosis-RECA_M ---------------------------------------- B Neisseria_meningitidis-RECA ---------------------------------------- B Neisseria_meningitidis-RECA_NEIMA ---------------------------------------- B Neisseria_meningitidis-RECA_VAR ---------------------------------------- B Xanthomonas_vasicola-RECA_XANAC ---------------------------------------- B Xanthomonas_vasicola-RECA_XANCP ---------------------------------------- B Xanthomonas_vasicola-YP_201580 ---------------------------------------- B Pseudomonas_aeruginosa-Q48F94 ---------------------------------------- B Pseudomonas_aeruginosa-RECA ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEF5 ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEFL ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPK ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPU ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSESM ---------------------------------------- ============================================================================ B DEINOCOCCUS_RADIODURANS ---------------------------------------- B Deinococcus_geothermalis ---------------------------------------- B Thermus_aquaticus-RECA ---------------------------------------- B Thermus_aquaticus-RECA_THET2 ---------------------------------------- B Thermus_aquaticus-RECA_THET8 ---------------------------------------- B Thermus_aquaticus-RECA_THETH ---------------------------------------- ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 170 180 190 200 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS ------------------------edlpgvgpataeklre A Archaeoglobus_fulgidus ------------------------edipgvgpetarklre A Pyrococcus_abyssi ------------------------edlpgvgpataeklre ============================================================================ A METHANOCOCCUS_VOLTAE ---------------------------lpgvgpstaeklv A Methanococcus_jannaschii ---------------------------lpgvgpttaeklk A Methanococcus_maripaludis ---------------------------lpgvgpstadkli ============================================================================ A SULFOLOBUS_SOLFATARICUS -----------------------tindlpgisqtvinkli A Desulfurococcus_amylolyticus -----------------------svrdipgvgssiadkle A Sulfolobus_acidocaldarius -----------------------slsdlsgvgqnilnklv A Sulfolobus_tokodaii -----------------------slsdlpgvgqsilnkli A Aeropyrum_pernix-RADA -----------------------ditdlpgvgpttaqklm A Aeropyrum_pernix-RADA_VAR_OH1 -----------------------ditdlpgvgpttaqklm A Aeropyrum_pernix-RADA_VAR_OH2 -----------------------ditdlpgvgpttaqklm A Aeropyrum_pernix-RADA_VAR_OH3 -----------------------ditdlpgvgpttaqklm A Aeropyrum_pernix-RADA_VAR_TB1 -----------------------ditdlpgvgpttaqklm A Aeropyrum_pernix-RADA_VAR_TB2 -----------------------ditdlpgvgpttaqklm A Aeropyrum_pernix-RADA_VAR_TB6 -----------------------ditdlpgvgpttaqklm ============================================================================ * HUMAN -pisrl-e---------------qc----ginandvkkle * S_CEREVISIAE -piekl-q---------------vn----gitmadvkklr * Apis_mellifera -liktl-e---------------gn----gitagdvkkle * Aspergillus_flavus -plsal-e------g--------va----gltgrdiklfv * Aspergillus_fumigatus -plsal-e------g--------va----gltsrdiklfv * Bovine -pisrl-e---------------qc----ginandvkkle * C_elegans -vidkl-e---------------ss----gissgdisklk * Candida_albicans -lieql-e---------------gn----ginasdikklk * Candida_glabrata -plekl-q---------------vn----gitstdikklr * Canis_lupus -pisrl-e---------------qc----ginandvkkle * Chaetomium_globosum -pllal-e------g--------vs----gltkreiqaiv * Coccidioides_immitis -plsal-evytfhigirrpisefmcqgvngltardiklli * Coprinus_cinereus -lvnkl-q---------------ea----gihandikkla * Cricetulus_griseus -pisrl-e---------------qc----gisandvkkle * Cryptococcus_neoformans --vakl-q---------------ea----gisaqdtkkla * Danio_rerio -pvsrl-e---------------qs----gisssdikkle * Debaryomyces_hansenii -lieql-e---------------gn----gitsgdirklk * D_melanogaster -svtkl-i---------------gg----sitakdikllq * D_pseudoobscura -nvtkl-i---------------gg----sitakdikllq * Emericella_nidulans -plssl-e------g--------ma----gltsrdiklfv * Encephalitozoon_cuniculi -sisel-k---------------ng----gilavdiakli * Eremothecium_gossypii vplerl-q---------------vn----gitnndlkklr * Chicken -pisrl-e---------------qc----ginandvkkle * Gibberella_zeae -plfal-e------g--------va----gltkrdiqlvv * Kluyveromyces_lactis -piekl-q---------------vn----gitsgdikklr * Mouse -pisrl-e---------------qc----ginandvkkle * Neurospora_crassa -plsal-e------g--------va----gltkrdiqliv * Rabbit -pvsrl-e---------------qc----ginandvkkle * Pichia_angusta -piqql-v---------------gn----gitpqdikklk * Rat -pisrl-e---------------qc----ginandvkkle * Schizosaccharomyces_pombe -plqml-e---------------gn----gitasdikkih * Strongylocentrotus_purpuratus -gisrl-e---------------as----gissndvkkle * Tetraodon_nigroviridis -plcrl-e---------------qc----gisasdikkle * Tribolium_castaneum -plskl-q---------------vn----gitagdlkkle * Ustilago_maydis -pvskl-e---------------ef----gisssdckkla * X_tropicalis -aisrl-e---------------qc----ginandvkkle * Yarrowia_lipolytica -pierl-a---------------vn----gitqtdinrlg * X_laevis-RA51A -aisrl-e---------------qc----ginandvkkle * X_laevis-RA51B -aitrl-e---------------qc----ginandvkkle Cryptosporidium_hominis -klehl-l---------------ps----gltkrdleilr Cryptosporidium_parvum -klehl-l---------------ps----gltkrdleilr Dictyostelium_discoideum lsinkl-e---------------gn----ginaadlkklq Entamoeba_histolytica -pirklig---------------la----gitegdckkle Leishmania_donovani -viqil-e---------------ny----gvassdikklm Leishmania_tropica -viqil-e---------------ny----gvassdikklm Plasmodium_berghei -kieql-l---------------ak----gfvkrdlellk Plasmodium_falciparum -kieql-l---------------ak----gfvkrdlellk Tetrahymena_thermophila -liakl-e---------------eh----ginnadvkkli Theileria_annulata -rlecl-l---------------sk----gllqrdldllr Theileria_parva -rlecl-l---------------sk----gllqrdldllr Trypanosoma_brucei -vlqim-e---------------ny----gvasadikklm Trypanosoma_cruzi -viqvl-e---------------sy----giasadikklm P Arabidopsis_thaliana -pveql-q---------------aa----giasvdvkklr P Oryza_sativa -pieql-q---------------as----giaaldvkklk P Maize-R51A1 -pieql-q---------------as----giaaldvkklk P Maize-R51A2 -pieql-q---------------as----giaaldvkklk ============================================================================ B E_COLI ---------------------------------------- B MYCOBACTERIUM_SMEGMATIS ---------------------------------------- B MYCOBACTERIUM_TUBERCULOSIS ---------------------------------------- B Acinetobacter_calcoaceticus ---------------------------------------- B Actinobacillus_pleuropneumoniae ---------------------------------------- B Actinobacillus_succinogenes ---------------------------------------- B Actinomyces_bovis ---------------------------------------- B Azotobacter_vinelandii ---------------------------------------- B Bacillus_clausii ---------------------------------------- B Bacillus_halodurans ---------------------------------------- B Bacillus_licheniformis ---------------------------------------- B Bacillus_megaterium ---------------------------------------- B Bacillus_subtilis ---------------------------------------- B Bordetella_pertussis ---------------------------------------- B Burkholderia_fungorum ---------------------------------------- B Chromobacterium_violaceum ---------------------------------------- B Clostridium_acetobutylicum ---------------------------------------- B Clostridium_thermocellum ---------------------------------------- B Colwellia_psychrerythraea ---------------------------------------- B Corynebacterium_efficiens ---------------------------------------- B Desulfotalea_psychrophila ---------------------------------------- B Enterococcus_faecalis ---------------------------------------- B Haemophilus_ducreyi ---------------------------------------- B Haemophilus_influenzae ---------------------------------------- B Histophilus_somni ---------------------------------------- B Kineococcus_radiotolerans ---------------------------------------- B Leifsonia_xyli ---------------------------------------- B Mannheimia_succiniciproducens ---------------------------------------- B Nitrosomonas_europaea ---------------------------------------- B Nitrosomonas_eutropha ---------------------------------------- B Oceanobacillus_iheyensis ---------------------------------------- B Pasteurella_multocida ---------------------------------------- B Photobacterium_profundum ---------------------------------------- B Photorhabdus_luminescens ---------------------------------------- B Proteus_mirabilis ---------------------------------------- B Pseudomonas_cepacia ---------------------------------------- B Pseudomonas_pseudomallei ---------------------------------------- B Shewanella_amazonensis ---------------------------------------- B Shewanella_putrefaciens ---------------------------------------- B Streptomyces_avermitilis ---------------------------------------- B Vibrio_alginolyticus ---------------------------------------- B Vibrio_angustum ---------------------------------------- B Vibrio_cholerae ---------------------------------------- B Vibrio_fischeri ---------------------------------------- B Vibrio_parahaemolyticus ---------------------------------------- B Vibrio_splendidus ---------------------------------------- B Vibrio_vulnificus ---------------------------------------- B Yersinia_enterocolitica ---------------------------------------- B Cupriavidus_metallidurans-Q1LR74 ---------------------------------------- B Cupriavidus_metallidurans-RECA ---------------------------------------- B Erwinia_carotovora-RECA ---------------------------------------- B Erwinia_carotovora-RECA_ERWCT ---------------------------------------- B Listeria_monocytogenes-RECA ---------------------------------------- B Listeria_monocytogenes-RECA_LISMF ---------------------------------------- B Neisseria_gonorrhoeae-RECA ---------------------------------------- B Neisseria_gonorrhoeae-RECA_VAR ---------------------------------------- B Salmonella_typhi-RECA ---------------------------------------- B Salmonella_typhi-RECA_SALPA ---------------------------------------- B Streptomyces_coelicolor-RECA ---------------------------------------- B Streptomyces_coelicolor-RECA_STRL ---------------------------------------- B Xylella_fastidiosa-RECA ---------------------------------------- B Xylella_fastidiosa-RECA_XYLFT ---------------------------------------- B Yersinia_pestis-RECA ---------------------------------------- B Yersinia_pestis-RECA_YERPS ---------------------------------------- B Mycobacterium_tuberculosis-RECA ---------------------------------------- B Mycobacterium_tuberculosis-RECA_M ---------------------------------------- B Neisseria_meningitidis-RECA ---------------------------------------- B Neisseria_meningitidis-RECA_NEIMA ---------------------------------------- B Neisseria_meningitidis-RECA_VAR ---------------------------------------- B Xanthomonas_vasicola-RECA_XANAC ---------------------------------------- B Xanthomonas_vasicola-RECA_XANCP ---------------------------------------- B Xanthomonas_vasicola-YP_201580 ---------------------------------------- B Pseudomonas_aeruginosa-Q48F94 ---------------------------------------- B Pseudomonas_aeruginosa-RECA ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEF5 ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEFL ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPK ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPU ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSESM ---------------------------------------- ============================================================================ B DEINOCOCCUS_RADIODURANS ---------------------------------------- B Deinococcus_geothermalis ---------------------------------------- B Thermus_aquaticus-RECA ---------------------------------------- B Thermus_aquaticus-RECA_THET2 ---------------------------------------- B Thermus_aquaticus-RECA_THET8 ---------------------------------------- B Thermus_aquaticus-RECA_THETH ---------------------------------------- ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 210 220 230 240 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxkxxxxxxaxkivekxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS agydtleaiavaspielkevagisegtalkiIqaarkaan A Archaeoglobus_fulgidus agystieavavaspselanvggitegnavkiIqaarklan A Pyrococcus_abyssi agfdtleaiavaspielkevagisegaalkiIqaarkaan ============================================================================ A METHANOCOCCUS_VOLTAE eagyidfmkiatatvgeltdiEgisekaAaKMImgardlc A Methanococcus_jannaschii eagytdfmkiatasigelteidgisekaAaRIIEaarelc A Methanococcus_maripaludis eggyldfmkiatatigeltdiEgisekaAaKMImaardlc ============================================================================ A SULFOLOBUS_SOLFATARICUS eagyssletlavaspqdlsvaagiplstAqKIIKEardal A Desulfurococcus_amylolyticus aagylsawsivvaraeelaertglpvltvqKIIEnarkml A Sulfolobus_acidocaldarius eagyssleavavatpqdlsvaagipqttAqRIIKEareal A Sulfolobus_tokodaii eagyssleavavaspqdlsvaagiplttAqRIIKEareal A Aeropyrum_pernix-RADA eagyttleaiaaatpqevsqatgipiltAqKIVDaareal A Aeropyrum_pernix-RADA_VAR_OH1 eagyttleaiaaatpqevsqatgipiltAqKIVDaareal A Aeropyrum_pernix-RADA_VAR_OH2 eagyttleaiaaatpqevsqatgipiltAqKIVDaareal A Aeropyrum_pernix-RADA_VAR_OH3 eagyttleaiaaatpqevsqatgipiltAqKtVDaareal A Aeropyrum_pernix-RADA_VAR_TB1 eagyttleaiaaatpqevsqatgipiltAqKIVDaareal A Aeropyrum_pernix-RADA_VAR_TB2 eagyttleaiaaatpqevsqatgipiltAqKIVDaareal A Aeropyrum_pernix-RADA_VAR_TB6 eagyttleaiaaatpqevsqatgipiltAqKIVDaareal ============================================================================ * HUMAN eagfhtveavayapkkeliniKgiseakAdKILaEaaklv * S_CEREVISIAE esglhtaeavayaprkdlleiKgiseakAdKLLnEaarlv * Apis_mellifera eagyytveavayapkkcliaiKgiseakAdKILQEasklv * Aspergillus_flavus dagyhtvesiaytpkrlleqiKgiseqkAtKVLvEaaklv * Aspergillus_fumigatus dagyhtvesiaytpkrlleqiKgiseqkAtKILvEaaklv * Bovine eagfhtveavayapkkeliniKgiseakAdKILtEaaklv * C_elegans eagyytyeslafttrrelrnvKgisdqkAeKIMKEamkfv * Candida_albicans aegfhtiesiaytpkrhlmtvKgisenkAeKIsaEaaklv * Candida_glabrata esglhtveavayapkkdlleiKgisetkAdRLLnEaarlv * Canis_lupus eagfhtveavayapkkelisiKgiseakAdKILtEaaklv * Chaetomium_globosum esglntveavaytpqrvleqvKgissqkAaKILaEasklv * Coccidioides_immitis dggyhtveavaytpkrmleqiKgiseqkAaKILaEatkiv * Coprinus_cinereus daglntveavaftpkknllaiRgiseqkAdKILaEaqkiv * Cricetulus_griseus eagfhtveavayapkkeliniKgiseakAdKILaEaaklv * Cryptococcus_neoformans dagfhtveavaftpkktlctiKgiseqkAdKILaEackmv * Danio_rerio dggfhtveavayapkkellniKgiseakAdKILtEaakmv * Debaryomyces_hansenii aegyhtiesiaytpkkalllvKgiseakAdKIslEaakvv * D_melanogaster qaslhtvesvanatkkqlmaipglgggkveQIItEanklv * D_pseudoobscura qaslhtvdavanatrkhllaipglggskvdQIIsEaskmv * Emericella_nidulans dagyhtvesiaytpkrlleqiKgiseqkAtKILvEaaklv * Encephalitozoon_cuniculi eagfttveslafapkrqllsiKgfsdikvdKLIKEaaklv * Eremothecium_gossypii englhtveavayaprkdlleiKgiseakAdKLLaEaarlv * Chicken eagyhtvesvahapkkellniKgiseakAdKILaEaaklv * Gibberella_zeae dggyntvesvaytprrvleqiKgiseqkAtKILaEasklv * Kluyveromyces_lactis esglhtaeavayaprkdlmeiKgiseakAdKLLaEasrlv * Mouse eagyhtveavayapkkeliniKgiseakAdKILtEaaklv * Neurospora_crassa dggfntvesvaytprrvleqiKgiseqkAgKILaEasklv * Rabbit eagfhteeavayapkkeliniKgiseakAdKILtEaaklv * Pichia_angusta eagfhtvesiaytpkrhivtvKgiseqkAdKLLmEasklv * Rat eagyhtveavayapkkeliniKgiseakAdKILaEaaklv * Schizosaccharomyces_pombe eagyytvesiaytpkrqllliKgiseakAdKLLgEasklv * Strongylocentrotus_purpuratus eagmhtvesvaystkkelcavKgiseakAdKILtEaqklv * Tetraodon_nigroviridis dagfhtieavayapkkellniKgiseakAdKILtEaaklv * Tribolium_castaneum dagfhsiesiaytpkkvlgaiKgiseakvdKLLaEaakfv * Ustilago_maydis esgyntvesiaftpkkqlllvKgvseakAdKILaEaarlv * X_tropicalis eagfhtveavayapkkeliniKgiseakAeKILaEaaklv * Yarrowia_lipolytica efglytvesvaytpkkhlltiKgiseakAdKLLsEasklv * X_laevis-RA51A eagfhtveavayapkkellniKgiseakAeKILaEaaklv * X_laevis-RA51B dagfhtveavayapkkellniKgiseakAeKILaEaaklv Cryptosporidium_hominis engyhtieclayapkkallsvKgiseqkcdKIksackelv Cryptosporidium_parvum engyhtieclayapkkallsvKgiseqkcdKIksackelv Dictyostelium_discoideum eqglntvqavafttkktltgiKgiseqkAdKLLaEakklv Entamoeba_histolytica eagfftvqsiaftpkkqlitiKgisdakAdKLLaEsskiv Leishmania_donovani ecgfytvesaayapkkailavKgisenkAeKIMaEcaklv Leishmania_tropica ecgfytvesaayapkkailavKgisenkAeKIMaEcaklv Plasmodium_berghei egglqtvecvayapmrtlcsiKgiseqkAeKLkKackelc Plasmodium_falciparum egglqtvecvayapmrtlcaiKgiseqkAeKLkKackelc Tetrahymena_thermophila dagfqtvesisytakknllqiKgmteakidKILDvaaklv Theileria_annulata eagystlecvayapqknllviKglseqkvlKIkaacrelc Theileria_parva eagystlecvayapqknllviKglseqkvlKIkaacrelc Trypanosoma_brucei ecgfltvesvayapkksilavKgiseakAeKIMaEccklt Trypanosoma_cruzi esgfytvesvayapkknilavKgisetkAdKIMaEcaklv P Arabidopsis_thaliana daglctvegvaytprkdllqiKgisdakvdKIVEaasklv P Oryza_sativa dsglytvesvaytprkdllqiKgiseakvdKIVEaasklv P Maize-R51A1 dsglhtveavaytprkdllqiKgiseakAdKIIEaaskiv P Maize-R51A2 daglctvesvaysprkdllqiKgiseakvdKIIEaasklv ============================================================================ B E_COLI ---------------------KqkalaaAlgqIEKqfgkg B MYCOBACTERIUM_SMEGMATIS ---------------------RekalelAmaqIDKnfgkg B MYCOBACTERIUM_TUBERCULOSIS ---------------------RekalelAmaqIEKsygkg B Acinetobacter_calcoaceticus ---------------------KskalqaAlsqIEKqfgkn B Actinobacillus_pleuropneumoniae ---------------------KekalaaAlaqIEKqfgkg B Actinobacillus_succinogenes ---------------------KskalaaAlgqIEKqfgkg B Actinomyces_bovis ---------------------RdkalelAlaqVEKsfgkg B Azotobacter_vinelandii ---------------------KkralaaAlgqIEKqfgkg B Bacillus_clausii ---------------------RkqaldmAlRhIEKqfgkg B Bacillus_halodurans ---------------------RkaaldmAlRqIEKqfgkg B Bacillus_licheniformis ---------------------RqaaldmAlKqIEKqfgkg B Bacillus_megaterium ---------------------RqaaldmAlKqIEKqfgkg B Bacillus_subtilis ---------------------RqaaldmAlKqIEKqfgkg B Bordetella_pertussis ---------------------KakalaaAlsqIEKqfgkg B Burkholderia_fungorum ---------------------KskalaaAlaqIEKqfgkg B Chromobacterium_violaceum ---------------------KskalaaAlaqIEKqfgkg B Clostridium_acetobutylicum ---------------------KlkaidaAmsqIEKqfgkg B Clostridium_thermocellum ---------------------KkkalemvlgqIEKqfgkg B Colwellia_psychrerythraea ---------------------KekalsaAlaqIERqfgkg B Corynebacterium_efficiens ---------------------RqkaldaAlaLIEKdfgkg B Desulfotalea_psychrophila ---------------------KagsvenAisqIQKqfgkg B Enterococcus_faecalis ---------------------RkvaldaAlKkIEKnfgkg B Haemophilus_ducreyi ---------------------KekalaaAlaqIEKqfgkg B Haemophilus_influenzae ---------------------KqkalaaAlgqIEKqfgkg B Histophilus_somni ---------------------KakaleaAlgqIEKqfgkg B Kineococcus_radiotolerans ---------------------RekaldaAlaaIDKnfgkg B Leifsonia_xyli ---------------------RekalvtAlaqIDRqfgkg B Mannheimia_succiniciproducens ---------------------KskalaaAlgqIEKqfgkg B Nitrosomonas_europaea ---------------------KnkalsaAlaqIEKqygkg B Nitrosomonas_eutropha ---------------------KnkaltaAlaqIEKqygkg B Oceanobacillus_iheyensis ---------------------RkqaldmAlRqIEKqfgkg B Pasteurella_multocida ---------------------KnkalaaAlgqIEKqfgkg B Photobacterium_profundum ---------------------KqkalaaAlgqIEKqfgkg B Photorhabdus_luminescens ---------------------KqkalaaAlgqIEKqfgkg B Proteus_mirabilis ---------------------KqkalaaAlgqIEKqfgkg B Pseudomonas_cepacia ---------------------KskalaaAlaqIEKqfgkg B Pseudomonas_pseudomallei ---------------------KskalaaAlaqIEKqfgkg B Shewanella_amazonensis ---------------------KekalaavlgqIEKqfgkg B Shewanella_putrefaciens ---------------------KekalaavlsqIEKqfgkg B Streptomyces_avermitilis ---------------------RekaldaAlaqIERqfgkg B Vibrio_alginolyticus ---------------------KqkalaaAlgqIEKqfgkg B Vibrio_angustum ---------------------KqkalaaAlgqIEKqfgkg B Vibrio_cholerae ---------------------KqkalaaAlgqIEKqfgkg B Vibrio_fischeri ---------------------KkkalaaAlgqIEKqfgkg B Vibrio_parahaemolyticus ---------------------KqkalaaAlgqIEKqfgkg B Vibrio_splendidus ---------------------KqkalaaAlgqIEKqfgkg B Vibrio_vulnificus ---------------------KqkalaaAlgqIEKqfgkg B Yersinia_enterocolitica ---------------------KqkalaaAlgqIEKqfgkg B Cupriavidus_metallidurans-Q1LR74 ---------------------KqkalaaAlsqIEKqfgkg B Cupriavidus_metallidurans-RECA ---------------------KqkalaaAlsqIEKqfgkg B Erwinia_carotovora-RECA ---------------------KqkalaaAlgqIEKqfgkg B Erwinia_carotovora-RECA_ERWCT ---------------------KqkalaaAlgqIEKqfgkg B Listeria_monocytogenes-RECA ---------------------RqaaldqAlKqIEKqfgkg B Listeria_monocytogenes-RECA_LISMF ---------------------RqaaldqAlKqIEKqfgkg B Neisseria_gonorrhoeae-RECA ---------------------KskalaaAlaqIEKsfgkg B Neisseria_gonorrhoeae-RECA_VAR ---------------------KskalaaAlaqIEKsfgkg B Salmonella_typhi-RECA ---------------------KqkalaaAlgqIEKqfgkg B Salmonella_typhi-RECA_SALPA ---------------------KqkalaaAmgqIEKqfgkg B Streptomyces_coelicolor-RECA ---------------------RekaldaAlaqIERqfgkg B Streptomyces_coelicolor-RECA_STRL ---------------------RekaldaAlaqIERqfgkg B Xylella_fastidiosa-RECA ---------------------KkralsvAlsqIEKqfgkg B Xylella_fastidiosa-RECA_XYLFT ---------------------KkralsvAlsqIEKqfgkg B Yersinia_pestis-RECA ---------------------KqkalaaAlgqIEKqfgkg B Yersinia_pestis-RECA_YERPS ---------------------KqkalaaAlgqIEKqfgkg B Mycobacterium_tuberculosis-RECA ---------------------RekalelAvaqIEKsygkg B Mycobacterium_tuberculosis-RECA_M ---------------------RekalelAmaqIEKsygkg B Neisseria_meningitidis-RECA ---------------------KskalaaAlaqIEKsfgkg B Neisseria_meningitidis-RECA_NEIMA ---------------------KskalaaAlaqIEKsfgkg B Neisseria_meningitidis-RECA_VAR ---------------------KskalaaAlaqIEKsfgkg B Xanthomonas_vasicola-RECA_XANAC ---------------------KkralsaAlsqIEKqfgkg B Xanthomonas_vasicola-RECA_XANCP ---------------------KkralsaAlsqIEKqfgkg B Xanthomonas_vasicola-YP_201580 ---------------------KkralaaAlsqIEKqfgkg B Pseudomonas_aeruginosa-Q48F94 ---------------------KkkalaaAlgqIERqfgkg B Pseudomonas_aeruginosa-RECA ---------------------KkralaaAlgqIERqfgkg B Pseudomonas_aeruginosa-RECA_PSEF5 ---------------------KkkalaaAlgqIERqfgkg B Pseudomonas_aeruginosa-RECA_PSEFL ---------------------KkkalaaAlgqIERqfgkg B Pseudomonas_aeruginosa-RECA_PSEPK ---------------------KkralaaAlgqIERqfgkg B Pseudomonas_aeruginosa-RECA_PSEPU ---------------------KkralaaAlgqIERqfgkg B Pseudomonas_aeruginosa-RECA_PSESM ---------------------KkkalaaAlgqIERqfgkg ============================================================================ B DEINOCOCCUS_RADIODURANS -------------------------rskAiEtamsqieka B Deinococcus_geothermalis -------------------------rlkAiEtamtqieka B Thermus_aquaticus-RECA -------------------------krkslEnalKtieke B Thermus_aquaticus-RECA_THET2 -------------------------krkAlEnalKaieke B Thermus_aquaticus-RECA_THET8 -------------------------krkAlEnalKaieke B Thermus_aquaticus-RECA_THETH -------------------------krkAlEnalKaieke ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxkxxxxxxaxkivekxxxxx 250 260 270 280 ----:----|----:----|----:----|----:----| Consensus xixfmxgxxxxxqqxdIxxIsTGSxxLDxlLxxGGIexGx ============================================================================ A PYROCOCCUS_FURIOSUS lgtFMradeylkKRatIgrISTGSksLDkLL-gGGIEtqa A Archaeoglobus_fulgidus iggFesGdkvleRRrsVkkITTGSkdLDeLL-gGGVEtqa A Pyrococcus_abyssi lgtFMradeylkKResIgrISTGSksLDkLL-gGGIEtqa ============================================================================ A METHANOCOCCUS_VOLTAE dLgFksGidllkQRstVwkLSTsSseLDsVL-gGGLEsqs A Methanococcus_jannaschii nLgFksGtevlsQRkNIwkLSTGSknLDeIL-gGGLEsqs A Methanococcus_maripaludis dLgFksGvellkQRqsVwrLSTGSteLDtVL-aGGIEsqs ============================================================================ A SULFOLOBUS_SOLFATARICUS dIrFktalevkkERmNVkkISTGSqaLDgLL-aGGIEtrt A Desulfurococcus_amylolyticus gItFktarevkqERsNIgkITTGSksLDeLL-gGGVEtkt A Sulfolobus_acidocaldarius dIrFktalevkkERmNtkkITTGSqaLDgLL-gGGIEtrt A Sulfolobus_tokodaii dIrFktalevkkERiNtkkITTGSqaLDgLL-gGGIEtrt A Aeropyrum_pernix-RADA nIdFktaydlkiEsmNIkkITTGSrnLDeLL-gGGIEtkt A Aeropyrum_pernix-RADA_VAR_OH1 nIdFktaydlkiEsmNIkkITTGSrnLDeLL-gGGIEtkt A Aeropyrum_pernix-RADA_VAR_OH2 nIdFktaydlkiEsmNIkkITTGSrnLDeLL-gGGIEtkt A Aeropyrum_pernix-RADA_VAR_OH3 nIdFktaydlkiEsmNIkkITTGSrnLDeLL-gGGIEtkt A Aeropyrum_pernix-RADA_VAR_TB1 nIdFktaydlkiEsmNIkkITTGSrnLDeLL-gGGIEtkt A Aeropyrum_pernix-RADA_VAR_TB2 nIdFktaydlkiEsmNIkkITTGSrnLDeLL-gGGIEtkt A Aeropyrum_pernix-RADA_VAR_TB6 nIdFktaydlkiEsmNIkkITTGSrnLDeLL-gGGIEtkt ============================================================================ * HUMAN pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * S_CEREVISIAE pMgFVtaadfhmRRsELicLTTGSknLDtLL-gGGVEtGs * Apis_mellifera vMgFksateihqtRsNIvfVTTGSseLDrLL-gGGIEtGs * Aspergillus_flavus pMgFttatemhaRRsELisITTGSkqLDtLL-gGGIEtGs * Aspergillus_fumigatus pMgFttatemhaRRsELisITTGSkqLDtLL-gGGIEtGs * Bovine pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * C_elegans qMgFttGaevhvKRsqLvqIrTGSasLDrLL-gGGIEtGs * Candida_albicans pLgFttasefhsRRsELicLTTGSkqLDtLL-gGGVEtGs * Candida_glabrata pMgFVtaadfhmRRsEMicLTTGSknLDtLL-gGGIEtGs * Canis_lupus pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * Chaetomium_globosum pMgFttatemhqRRsELisITTGSkqLDtLL-aGGIEtGs * Coccidioides_immitis pMgFttatemhaRRaDLicITTGSrqLDtLL-aGGVEtGs * Coprinus_cinereus pLgFqsatevhaRRsELvhITTGSkqLDaLL-gGGIEtGa * Cricetulus_griseus pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * Cryptococcus_neoformans pMgFttateihsRRsELvhITTGStgLDtIL-gGGIEtGa * Danio_rerio pMgFttatefhqRRaEIiqISTGSkeLDkLL-qGGIEtGs * Debaryomyces_hansenii pLgFttasefhsRRsELicITTGSkqLDtLL-gGGIEtGs * D_melanogaster pLgFLsartfyqmRaDVvqLSTGSkeLDkLL-gGGIEtGs * D_pseudoobscura pLgFLsartfhqmRaDVvmLTTGSkeLDkLL-gGGIEtGs * Emericella_nidulans pMgFttatemhaRRsELisITTGSkqLDtLL-gGGIEtGs * Encephalitozoon_cuniculi pMgFttasayhqRRsELvyLTTGSseVDkLL-sGGfEsGs * Eremothecium_gossypii pMgFVtaadfhlRRaEMicLTTGSknLDtLL-gGGIEtGs * Chicken pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * Gibberella_zeae pMgFttatemhqRRsELisITTGSknLDtLL-aGGIEtGs * Kluyveromyces_lactis pMgFVtaadfhlRRnEMicLTTGSknLDtLL-gGGIEtGs * Mouse pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * Neurospora_crassa pMgFttatemhqRRsELisITTGSknLDtLL-aGGIEtGs * Rabbit pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * Pichia_angusta pLgFttatefhqRRsELicLTTGSkqLDtLL-gGGIEtGa * Rat pMgFttatefhqRRsEIiqITTGSkeLDkLL-qGGIEtGs * Schizosaccharomyces_pombe pMgFttateyhiRRsELitITTGSkqLDtLL-qGGVEtGs * Strongylocentrotus_purpuratus pMgFttatqfhqQRsEIiqVTTGSkeLDkLL-qGGIEtGs * Tetraodon_nigroviridis pMgFttatefhqRRaEIiqISTGSkeLDkLL-qGGIEtGs * Tribolium_castaneum nMgFttatdihrRRaNIiqLTTGSkeLDkLL-gGGIEtGs * Ustilago_maydis pMgFttatefhaRRnELisITTGSknLDaIL-gGGMEtGs * X_tropicalis pMgFttatefhqRRsEIiqISTGSkeLDkLL-qGGIEtGs * Yarrowia_lipolytica pLgFttasdvhqtRsgLitLTTGSsqLDtLL-gGGIEtGa * X_laevis-RA51A pMgFttatefhqRRsEIiqISTGSkeLDkLL-qGGVEtGs * X_laevis-RA51B pMgFttatefhqRRsEIiqIgTGSkeLDkLL-qGGIEtGs Cryptosporidium_hominis aMgFcsGteyleaRtNLikfTTGSsqLDrLL-qGGIEtGs Cryptosporidium_parvum aMgFcsGteyleaRtNLikfTTGSsqLDrLL-qGGIEtGs Dictyostelium_discoideum fMgFrtatdinkaRaEIiqITTGSkefDsLL-dGGIEsGs Entamoeba_histolytica pLaFtnaaelnnlRkEtirITTGSreLDkLL-cGGfEtGs Leishmania_donovani pMgFtsavayheaRkEIimVTTGSreVDkLL-gGGIEtGs Leishmania_tropica pMgFtsavayheaRkEIimVTTGSreVDkLL-gGGIEtGs Plasmodium_berghei nsgFcnaidyhdaRqNLikfTTGSkqLDaLL-kGGIEtGg Plasmodium_falciparum nsgFcnaidyhdaRqNLikfTTGSkqLDaLL-kGGIEtGg Tetrahymena_thermophila pndFqtaaeyyvKRqsVinLTTGSteLDkLL-gGGfEtGs Theileria_annulata hLgFcsGqdyleaRgNLikfTTGSsqLDkLL-qGGVEtGs Theileria_parva hLgFcsGqdyleaRgNLikfTTGSaqLDkLL-qGGVEtGs Trypanosoma_brucei pMgFtratvfqeQRkEtimVTTGSreVDkLL-gGGIEvGs Trypanosoma_cruzi pMgFtsavvyheaRkEIimVTTGSreVDkLL-gGGIEtGg P Arabidopsis_thaliana pLgFtsasqlhaQRqEIiqITSGSreLDkVL-eGGIEtGs P Oryza_sativa pLgFtsasqlhaQRlEIiqVTTGSreLDkIL-dGGIEtGs P Maize-R51A1 pLgFtsasqlhaQRlEIiqVTTGSreLDkIL-eGGIEtGs P Maize-R51A2 pLgFtsasqlhaQRlEIiqLTTGSreLDqIL-dGGIEtGs ============================================================================ B E_COLI sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B MYCOBACTERIUM_SMEGMATIS sVmrL-Ge-ev-RQ-pIsvIpTGSisLDvaLgiGGLprGr B MYCOBACTERIUM_TUBERCULOSIS sVmrL-Gd-em-RQ-pIsvIpTGSiaLDvaLgiGGLprGr B Acinetobacter_calcoaceticus tVmrL-Gd-nt-vQ-aVeaVSTGSltLDiaLgiGGLpkGr B Actinobacillus_pleuropneumoniae sImrL-Gd-tq-al-DIeaVSTGSigLDaaLgiGGLpmGr B Actinobacillus_succinogenes aImkL-Gd-rp-dm-DVesVSTGSigLDvaLgiGGLpmGr B Actinomyces_bovis aVmrL-Ge-ea-RQ-pIsvIpTGSiaLDvaLgiGGLprGr B Azotobacter_vinelandii aVmrM-Gd-he-RQ-aIpaISTGSlgLDiaLgiGGLpkGr B Bacillus_clausii sImkL-Ge-qa-EQ-rVstVSSGTlaLDiaLgvGGypkGr B Bacillus_halodurans sImkL-Ge-qa-EQ-rVstISSGalaLDiaLgvGGyprGr B Bacillus_licheniformis sImkL-Ge-qt-Et-rIstVpSGSlaLDaaLgvGGyprGr B Bacillus_megaterium sImkL-Ge-qt-EK-rIstIpSGSlaLDiaLgvGGyprGr B Bacillus_subtilis sImkL-Ge-kt-dt-rIstVpSGSlaLDtaLgiGGyprGr B Bordetella_pertussis sImry-Gd-nevEh-DIqvVSTGSlgLDiaLgvGGLprGr B Burkholderia_fungorum sVmrL-Ga-ge-vieDIqvVSTGSlgLDiaLgvGGLprGr B Chromobacterium_violaceum sImrM-sdnqi-tE-NLqvISTGSltLDlaLgvGGLprGr B Clostridium_acetobutylicum aImkL-Ge-qd-il-NIdaISTGclsLDiaLgiGGVprGr B Clostridium_thermocellum aVmkL-Ge-nt-hm-NIetIpTGalgLDiaLgvGGVprGr B Colwellia_psychrerythraea sImkL-Gd-nt-tm-DVetISTGSlgLDiaLgaGGLpmGr B Corynebacterium_efficiens aVmrL-Gd-en-Rp-pIqvISSGNtaLDiaLgiGGfprGr B Desulfotalea_psychrophila sImrL-Ge-qa-lE-aIpvISTGalsLDiaLgvGGLpkGr B Enterococcus_faecalis sImkL-Ge-ka-dQ-kIstIpSGSlaLDvaLgvGGyprGr B Haemophilus_ducreyi sImrL-Gd-tq-al-DIeaVSTGSigLDaaLgiGGLpmGr B Haemophilus_influenzae sImkL-Gd-tk-tl-DVesISTGSlgLDvaLgiGGLpmGr B Histophilus_somni aImkL-Ge-tq-Kl-DIeaISTGSlsLDvaLgiGGLpmGr B Kineococcus_radiotolerans sVmrL-Gd-ev-Rp-pIevIpTGSisLDvaLgiGGLprGr B Leifsonia_xyli sVmrL-Gs-de-Ra-pVevVpTGSiaLDvaLgiGGLprGr B Mannheimia_succiniciproducens aImkL-Gd-tq-al-DVesISTGSigLDvaLgiGGLpmGr B Nitrosomonas_europaea sImrL-Gdsdv-aK-DIqvVSTGSlgLDiaLgvGGLprGr B Nitrosomonas_eutropha sImrL-Gdsdv-aK-DIqvVSTGSlsLDiaLgvGGLprGr B Oceanobacillus_iheyensis sImkM-Ge-ne-ip-kIatIpSGSlaLDvaLgiGGyprGr B Pasteurella_multocida sImkL-Gd-tq-al-DVeaVSTGSlsLDvaLgiGGLpmGr B Photobacterium_profundum sImkL-Gd-nr-tm-DIetISTGSlsLDiaLgaGGLpmGr B Photorhabdus_luminescens sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B Proteus_mirabilis sImrL-Ge-dr-sm-NVetISTGSlsLDvaLgaGGLprGr B Pseudomonas_cepacia sImrM-Gdgea-aE-DIqvVSTGSlgLDiaLgvGGLprGr B Pseudomonas_pseudomallei sImrL-Gd-ge-aveDIqvVSTGSlgLDiaLgvGGLprGr B Shewanella_amazonensis sImkL-Ge-dr-sm-DVetISTGSlsLDvaLgaGGLpmGr B Shewanella_putrefaciens sImkL-Ge-dr-sm-DVetISTGSlsLDvaLgaGGLpmGr B Streptomyces_avermitilis aVmrL-Ge-rp-nE-pIevIpTGStaLDvaLgvGGLprGr B Vibrio_alginolyticus sImrL-Gd-nr-am-DVetISTGSlsLDiaLgaGGLpmGr B Vibrio_angustum sImkL-Gd-nr-tm-DIetISTGSlsLDiaLgaGGLpmGr B Vibrio_cholerae sImrL-Gd-nr-am-DVetISTGSlsLDiaLgaGGLpmGr B Vibrio_fischeri sImkL-Gd-nr-tm-DVetVSTGSlsLDiaLgaGGLpmGr B Vibrio_parahaemolyticus sImrL-Gd-nr-am-DVetISTGSlsLDiaLgaGGLpmGr B Vibrio_splendidus sImrL-Gd-nr-tm-DVetISTGSlsLDiaLgaGGLpmGr B Vibrio_vulnificus sImrL-Gd-nr-am-DVetISTGSlsLDiaLgaGGLpmGr B Yersinia_enterocolitica sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B Cupriavidus_metallidurans-Q1LR74 sImrL-Gd-geiEQ-DIqvVSTGSlgLDiaLgvGGLprGr B Cupriavidus_metallidurans-RECA sImrL-Gd-geiEQ-DIqvVSTGSlgLDiaLgvGGLprGr B Erwinia_carotovora-RECA sImrL-Ge-dr-sm-NVetISTGSlsLDvaLgaGGLprGr B Erwinia_carotovora-RECA_ERWCT sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B Listeria_monocytogenes-RECA sImkL-Ge-hs-dQ-NIstISSGSlaLDiaLgvGGyprGr B Listeria_monocytogenes-RECA_LISMF sImkL-Ge-hs-dQ-NIstISSGSlaLDiaLgvGGyprGr B Neisseria_gonorrhoeae-RECA aImkMdGs-qq-EE-NLevISTGSlgLDlaLgvGGLprGr B Neisseria_gonorrhoeae-RECA_VAR aImkMdGs-qq-EE-NLevISTGSlgLDlaLgvGGLrrGr B Salmonella_typhi-RECA sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B Salmonella_typhi-RECA_SALPA sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B Streptomyces_coelicolor-RECA aVmrM-Gd-rt-nE-pIevIpTGStaLDvaLgvGGIprGr B Streptomyces_coelicolor-RECA_STRL aVmrM-Gd-rt-nE-pIevIpTGStaLDvaLgvGGIprGr B Xylella_fastidiosa-RECA sVmrM-Gd-rv-iE-aVeaIpTGSlmLDlaLgiGGLpkGr B Xylella_fastidiosa-RECA_XYLFT sVmrM-Gd-rv-iE-aVeaIpTGSlmLDlaLgiGGLpkGr B Yersinia_pestis-RECA sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B Yersinia_pestis-RECA_YERPS sImrL-Ge-dr-sm-DVetISTGSlsLDiaLgaGGLpmGr B Mycobacterium_tuberculosis-RECA sVmrL-Gd-ea-RQ-pIsvIpTGSiaLDvaLgiGGLprGr B Mycobacterium_tuberculosis-RECA_M sVmrL-Gd-em-RQ-pIsvIpTGSiaLDvaLgiGGLprGr B Neisseria_meningitidis-RECA aImkMdGs-qq-EE-NLevISTGSlgLDlaLgvGGLprGr B Neisseria_meningitidis-RECA_NEIMA aImkMdGs-qq-EE-NLevISTGSlgLDlaLgvGGLprGr B Neisseria_meningitidis-RECA_VAR aImkMdGs-qq-EE-NLevISTGSlgLDlaLgvGGLprGr B Xanthomonas_vasicola-RECA_XANAC sVmrM-Gd-rv-iE-aVevIpTGSlmLDiaLgiGGLpkGr B Xanthomonas_vasicola-RECA_XANCP sVmrM-Gd-rv-iE-aVevIpTGSlmLDiaLgiGGLpkGr B Xanthomonas_vasicola-YP_201580 sVmrM-Gd-rv-iE-aVevIpTGSlmLDiaLgtGGLpkGr B Pseudomonas_aeruginosa-Q48F94 aVmrM-Gd-hd-RQ-aIpaISTGSlgLDiaLgiGGLpkGr B Pseudomonas_aeruginosa-RECA aVmrM-Gd-he-RQ-aIpaISTGSlgLDiaLgiGGLpkGr B Pseudomonas_aeruginosa-RECA_PSEF5 aVmrM-Gd-hd-RQ-aIpaISTGSlgLDiaLgiGGLpkGr B Pseudomonas_aeruginosa-RECA_PSEFL aVmrM-Gd-hd-RQ-aIpaISTGSlgLDiaLgiGGLpkGr B Pseudomonas_aeruginosa-RECA_PSEPK aVmrM-Gd-he-RQ-gIpaISTGSlgLDiaLgiGGLpkGr B Pseudomonas_aeruginosa-RECA_PSEPU aVmrM-Gd-he-RQ-aIpaISTGSlgLDiaLgiGGLpkGr B Pseudomonas_aeruginosa-RECA_PSESM aVmrM-Gd-hd-RQ-aIpaISTGSlgLDiaLgiGGLpkGr ============================================================================ B DEINOCOCCUS_RADIODURANS fgkgsimklgaesKlDVqvVSTGSlsLDlaLgvGGIprGr B Deinococcus_geothermalis fgkgsimrlgaesKlDVqaVSTGSlsLDlaLgvGGIprGr B Thermus_aquaticus-RECA fgkgavmrlgempKlqVdvIpTGSlgLDlaLgiGGIprGr B Thermus_aquaticus-RECA_THET2 fgkgavmrlgempKqqVdvIpTGSlaLDlaLgiGGIprGr B Thermus_aquaticus-RECA_THET8 fgkgavmrlgempKqqVdvIpTGSlaLDlaLgiGGIprGr B Thermus_aquaticus-RECA_THETH fgkgavmrlgempKqqVdvIpTGSlaLDlaLgiGGIprGr ============================================================================ Consensus xixfmxgxxxxxqqxdIxxIsTGSxxLDxlLxxGGIexGx 290 300 310 320 ----:----|----:----|----:----|----:----| Consensus ItELFxxxxxxxxxxxxxxxxxGxfxSGKTqIxhslxvsx ============================================================================ A PYROCOCCUS_FURIOSUS ITEVF-----------------GeFgSGKTQLaHTLaVmv A Archaeoglobus_fulgidus ITEfF-----------------GeFgSGKTQIcHqLaVNv A Pyrococcus_abyssi ITEVF-----------------GeFgSGKTQLaHTLaVmv ============================================================================ A METHANOCOCCUS_VOLTAE VTEfa-----------------GvFgSGKTQImHqscVNl A Methanococcus_jannaschii VTEfa-----------------GmFgSGKTQIaHqacVNl A Methanococcus_maripaludis VTEfa-----------------GmFgSGKTQImHqtcVNl ============================================================================ A SULFOLOBUS_SOLFATARICUS MTEfF-----------------GeFgSGKTQLcHqLsVNv A Desulfurococcus_amylolyticus ITEfF-----------------GeYgSGKTQIcHqLsVNv A Sulfolobus_acidocaldarius MTEfF-----------------GeFgSGKTQLcHqIsISv A Sulfolobus_tokodaii MTELF-----------------GeFgSGKTQLcHqLsVNv A Aeropyrum_pernix-RADA ITELF-----------------GeFgSGKTQIcHqLsVNv A Aeropyrum_pernix-RADA_VAR_OH1 ITELF-----------------GeFgSGKTQIcHqLsVNv A Aeropyrum_pernix-RADA_VAR_OH2 ITELF-----------------GeFgSGKTQIcHqLsVNv A Aeropyrum_pernix-RADA_VAR_OH3 ITELF-----------------GeFgSGKTQIcHqLsVNv A Aeropyrum_pernix-RADA_VAR_TB1 ITELF-----------------GeFgSGKTQIcHqLsVNv A Aeropyrum_pernix-RADA_VAR_TB2 ITELF-----------------GeFgSGKTQIcHqLsVNv A Aeropyrum_pernix-RADA_VAR_TB6 ITELF-----------------GeFgSGKTQIcHqLsVNv ============================================================================ * HUMAN ITEMF-----------------GeFrTGKTQIcHTLaVTc * S_CEREVISIAE ITELF-----------------GeFrTGKSQLcHTLaVTc * Apis_mellifera ITEIF-----------------GeFrSGKTQLcHTLaVNc * Aspergillus_flavus ITEIF-----------------GeFrTGKSQIcHTLaVTc * Aspergillus_fumigatus ITEIF-----------------GeFrTGKSQIcHTLaVTc * Bovine ITEMF-----------------GeFrTGKTQIcHTLaVTc * C_elegans ITEVY-----------------GeYrTGKTQLcHSLaVlc * Candida_albicans ITEVF-----------------GeFrTGKSQLcHTLaVTc * Candida_glabrata ITELF-----------------GeFrTGKSQLcHSLaVTc * Canis_lupus ITEMF-----------------GeFrTGKTQIcHTLaVTc * Chaetomium_globosum VTELF-----------------GeFrTGKSQIcHTLaVTc * Coccidioides_immitis ITEIF-----------------GeFrTGKSQIcHTLaVTc * Coprinus_cinereus ITELF-----------------GeFrTGKSQIcHTLaVTc * Cricetulus_griseus ITEMF-----------------GeFrTGKTQIcHTLaVTc * Cryptococcus_neoformans ITELYgkslrslvaspiantstGeFrTGKSQLcHTLaVTc * Danio_rerio ITEMF-----------------GeFrTGKTQLcHTLaVTc * Debaryomyces_hansenii ITEVF-----------------GeFrTGKSQLcHTLaVTc * D_melanogaster ITEIF-----------------GeFrcGKTQLcHTLaVTc * D_pseudoobscura ITEIF-----------------GeFrcGKTQIcHTLaVTc * Emericella_nidulans ITEIF-----------------GeFrTGKSQIcHTLaVTc * Encephalitozoon_cuniculi ITEIF-----------------GeFrTGKTQLcHTVaVTc * Eremothecium_gossypii ITELF-----------------GeFrTGKSQLcHTLaVTc * Chicken ITELF-----------------GeFrTGKTQLcHTLaVTc * Gibberella_zeae VTELF-----------------GeFrTGKSQIcHTLaVTc * Kluyveromyces_lactis ITELF-----------------GeFrTGKSQLcHTLaVTc * Mouse ITEMF-----------------GeFrTGKTQIcHTLaVTc * Neurospora_crassa VTEIF-----------------GeFrTGKSQIcHTLaVTc * Rabbit ITEMF-----------------GeFrTGKTQIcHTLaVTc * Pichia_angusta ITEVF-----------------GeFrTGKSQLcHTLaVTc * Rat ITEMF-----------------GeFrTGKTQIcHTLaVTc * Schizosaccharomyces_pombe ITELF-----------------GeFrTGKSQIcHTLaVTc * Strongylocentrotus_purpuratus ITEIF-----------------GeFrTGKTQLcHTMaVTc * Tetraodon_nigroviridis ITEMF-----------------GeFrTGKTQLcHTLaVTc * Tribolium_castaneum ITEIF-----------------GeFrTGKTQIcHTLaVTc * Ustilago_maydis ITELY-----------------GeFrTGKSQLcHTLaVTc * X_tropicalis ITEMF-----------------GeFrTGKTQLcHTLaVTc * Yarrowia_lipolytica ITEMF-----------------GeFrTGKSQLcHTLaVTc * X_laevis-RA51A ITEMF-----------------GeFrTGKTQLcHTLaVTc * X_laevis-RA51B ITEMF-----------------GeFrTGKTQLcHTLaVTc Cryptosporidium_hominis ITEIF-----------------GeFrTGKTQLcHTLaVTc Cryptosporidium_parvum ITEIF-----------------GeFrTGKTQLcHTLaVTc Dictyostelium_discoideum ITEIF-----------------GeFrTGKTQIcHTLcVTc Entamoeba_histolytica ITELF-----------------GeFrTGKTQLcHqLcVTc Leishmania_donovani ITELF-----------------GeFrTGKTQLcHTLcVTc Leishmania_tropica ITELF-----------------GeFrTGKTQLcHTLcVTc Plasmodium_berghei ITELF-----------------GeFrTGKSQLcHTLaITc Plasmodium_falciparum ITELF-----------------GeFrTGKSQLcHTLaITc Tetrahymena_thermophila LTEIF-----------------GeFrTGKTQIcHTLcITc Theileria_annulata ITEIi-----------------GeFkTGKSQLcHTLaVTc Theileria_parva ITEIi-----------------GeFkTGKSQLcHTLaVTc Trypanosoma_brucei ITELF-----------------GeFrTGKTQLcHTLcVTc Trypanosoma_cruzi ITELF-----------------GeFrTGKTQLcHTLcVTc P Arabidopsis_thaliana ITELY-----------------GeFrSGKTQLcHTLcVTc P Oryza_sativa ITEIY-----------------GeFrSGKTQLcHTLcVTc P Maize-R51A1 ITEIY-----------------GeFrSGKTQLcHTpcVTc P Maize-R51A2 ITEMY-----------------GeFrSGKTQLcHTLcVTc ============================================================================ B E_COLI IvEIY-----------------GpesSGKTtLtlqViaaa B MYCOBACTERIUM_SMEGMATIS ViEIY-----------------GpesSGKTtValhavaNa B MYCOBACTERIUM_TUBERCULOSIS VvEIY-----------------GpesSGKTtValhavaNa B Acinetobacter_calcoaceticus IvEIY-----------------GpesSGKTtMtlqaiaqc B Actinobacillus_pleuropneumoniae IvEIY-----------------GpesSGKTtLtlSViaqa B Actinobacillus_succinogenes IvEIF-----------------GpesSGKTtLtlSViaqa B Actinomyces_bovis IvEIY-----------------GpesSGKTtValhavaNa B Azotobacter_vinelandii IvEIY-----------------GpesSGKTtLtlStiaea B Bacillus_clausii ViEVY-----------------GpesSGKTtValhaiaev B Bacillus_halodurans ViEVY-----------------GpesSGKTtValhaiaev B Bacillus_licheniformis IiEVY-----------------GpesSGKTtValhaiaev B Bacillus_megaterium VvEVY-----------------GpesSGKTtValhaiaev B Bacillus_subtilis IiEVY-----------------GpesSGKTtValhaiaev B Bordetella_pertussis ViEVY-----------------GpesSGKTtLtlqViaem B Burkholderia_fungorum VvEIY-----------------GpesSGKTtLtlqViaem B Chromobacterium_violaceum VvEIY-----------------GpesSGKTtLclqavaea B Clostridium_acetobutylicum VvEIY-----------------GpesSGKTtValhIlaea B Clostridium_thermocellum IvEIF-----------------GpesSGKTtValhIiaea B Colwellia_psychrerythraea VvEIY-----------------GpesSGKTtLtleViaea B Corynebacterium_efficiens IvEVY-----------------GpesSGKTtValhaiaqa B Desulfotalea_psychrophila MTEIY-----------------GpesSGKTtLalhVvaea B Enterococcus_faecalis IiEVY-----------------GpesSGKTtVslhaiaev B Haemophilus_ducreyi IvEIY-----------------GpesSGKTtLtlSViaqa B Haemophilus_influenzae IvEIF-----------------GpesSGKTtLtlSViaqa B Histophilus_somni IvEIF-----------------GpesSGKTtLtlSViaqa B Kineococcus_radiotolerans VvEIY-----------------GpesSGKTtValhavaSa B Leifsonia_xyli IvEIY-----------------GpesSGKTtLtlhaiaNa B Mannheimia_succiniciproducens VvEIF-----------------GpesSGKTtLtlSViaqa B Nitrosomonas_europaea IiEIY-----------------GpesSGKTtLtlqaiaem B Nitrosomonas_eutropha IiEIY-----------------GpesSGKTtLtlqViaem B Oceanobacillus_iheyensis VvEIY-----------------GpesSGKTtValhaiaea B Pasteurella_multocida IvEIF-----------------GpesSGKTtLtlSViaqa B Photobacterium_profundum IvEIY-----------------GpesSGKTtLtletiaaa B Photorhabdus_luminescens IvEIY-----------------GpesSGKTtLtlqViaaa B Proteus_mirabilis IvEIY-----------------GpesSGKTtLtlqViaSa B Pseudomonas_cepacia VvEIY-----------------GpesSGKTtLtlqViael B Pseudomonas_pseudomallei VvEIY-----------------GpesSGKTtLtlqViaem B Shewanella_amazonensis IvEIY-----------------GpesSGKTtLtleViaaa B Shewanella_putrefaciens IvEIY-----------------GpesSGKTtLtleViaaa B Streptomyces_avermitilis VvEVY-----------------GpesSGKTtLtlhavaNa B Vibrio_alginolyticus IvEIY-----------------GpesSGKTtLtleLiaaa B Vibrio_angustum IvEIY-----------------GpesSGKTtLtletiaaa B Vibrio_cholerae IvEIF-----------------GpesSGKTtLtleLiaaa B Vibrio_fischeri IvEIF-----------------GpesSGKTtLtleLiaaa B Vibrio_parahaemolyticus IvEIY-----------------GpesSGKTtLtleLiaaa B Vibrio_splendidus IvEVY-----------------GpesSGKTtLtleLiaaa B Vibrio_vulnificus IvEIF-----------------GpesSGKTtLtleLiaaa B Yersinia_enterocolitica IvEIY-----------------GpesSGKTtLtlqViaaa B Cupriavidus_metallidurans-Q1LR74 VvEIY-----------------GpesSGKTtLtlqVvaem B Cupriavidus_metallidurans-RECA VvEIY-----------------GpesSGKTtLtlqVvaem B Erwinia_carotovora-RECA IvEIY-----------------GpesyGKTtLtlqViaaa B Erwinia_carotovora-RECA_ERWCT IvEIY-----------------GpesSGKTtLtlqViaaa B Listeria_monocytogenes-RECA IiEVY-----------------GpesSGKTtValhaiaev B Listeria_monocytogenes-RECA_LISMF IiEVY-----------------GpesSGKTtValhaiaev B Neisseria_gonorrhoeae-RECA IvEIF-----------------GpesSGKTtLcleavaqc B Neisseria_gonorrhoeae-RECA_VAR IvEIF-----------------GpesSGKTtLcleavaqc B Salmonella_typhi-RECA IvEIY-----------------GpesSGKTtLtlqViaaa B Salmonella_typhi-RECA_SALPA IvEIY-----------------GpesSGKTtLtlqViaaa B Streptomyces_coelicolor-RECA VvEVY-----------------GpesSGKTtLtlhavaNa B Streptomyces_coelicolor-RECA_STRL VvEVY-----------------GpesSGKTtLtlhavaNa B Xylella_fastidiosa-RECA VvEIY-----------------GpesSGKTtLtlqaiaqc B Xylella_fastidiosa-RECA_XYLFT VvEIY-----------------GpesSGKTtLtlqaiaqc B Yersinia_pestis-RECA IvEIY-----------------GpesSGKTtLtlqViaaa B Yersinia_pestis-RECA_YERPS IvEIY-----------------GpesSGKTtLtlqViaaa B Mycobacterium_tuberculosis-RECA ViEIY-----------------GpesSGKTtValhavaNa B Mycobacterium_tuberculosis-RECA_M VvEIY-----------------GpesSGKTtValhavaNa B Neisseria_meningitidis-RECA IvEIF-----------------GpesSGKTtLcleavaqc B Neisseria_meningitidis-RECA_NEIMA IvEIF-----------------GpesSGKTtLcleavaqc B Neisseria_meningitidis-RECA_VAR IvEIF-----------------GpesSGKTtLcleavaqc B Xanthomonas_vasicola-RECA_XANAC VvEIY-----------------GpesSGKTtLtlqaiaec B Xanthomonas_vasicola-RECA_XANCP VvEIY-----------------GpesSGKTtLtlqaiaec B Xanthomonas_vasicola-YP_201580 VvEIY-----------------GpesSGKTtLtlqaiaqc B Pseudomonas_aeruginosa-Q48F94 IvEIY-----------------GpesSGKTtLtlSViaqa B Pseudomonas_aeruginosa-RECA IvEIY-----------------GpesSGKTtLtlSViaea B Pseudomonas_aeruginosa-RECA_PSEF5 IvEIY-----------------GpesSGKTtLtlSViaqa B Pseudomonas_aeruginosa-RECA_PSEFL IvEIY-----------------GpesSGKTtLtlSViaqa B Pseudomonas_aeruginosa-RECA_PSEPK IvEIY-----------------GpesSGKTtLtlSViaea B Pseudomonas_aeruginosa-RECA_PSEPU IvEIY-----------------GpesSGKTtLtlSViaea B Pseudomonas_aeruginosa-RECA_PSESM IvEIY-----------------GpesSGKTtLtlSViaqa ============================================================================ B DEINOCOCCUS_RADIODURANS ITEIY-----------------GpesgGKTtLalaIvaqa B Deinococcus_geothermalis ITEIY-----------------GpesgGKTtLalSViaqa B Thermus_aquaticus-RECA VTEIF-----------------GpesgGKTtLalTIiaqa B Thermus_aquaticus-RECA_THET2 IvEIY-----------------GpesgGKTtLalTIiaqa B Thermus_aquaticus-RECA_THET8 IvEIY-----------------GpesgGKTtLalTIiaqa B Thermus_aquaticus-RECA_THETH IvEIY-----------------GpesgGKTtLalTIiaqa ============================================================================ Consensus ItELFxxxxxxxxxxxxxxxxxGxfxSGKTqIxhslxvsx 330 340 350 360 ----:----|----:----|----:----|----:----| Consensus QxxxxxxxxxxxxxxxxxxxxxgxcvFVDxEntfrPerix ============================================================================ A PYROCOCCUS_FURIOSUS Qlppeegg------------lnGsvIWIDtENTFRPERIr A Archaeoglobus_fulgidus Qlpedegg------------leGsvIiIDtENTFRPERIi A Pyrococcus_abyssi Qlppeegg------------lnGsvIWIDtENTFRPERIr ============================================================================ A METHANOCOCCUS_VOLTAE Qnp--eflfydeeavskgevaqpkaVYIDtEgTFRPERIm A Methanococcus_jannaschii Qcp--erivad-daikdeilnepkaVYIDtEgTFRPERIv A Methanococcus_maripaludis Qir--ekifadlegvveeeleapkaVYIDtEgTFRPERVv ============================================================================ A SULFOLOBUS_SOLFATARICUS Qlppekgg------------lsGkaVYIDtEgTFRwERIe A Desulfurococcus_amylolyticus Qltpekgg------------lnGraVYIDtEgTFRwERIe A Sulfolobus_acidocaldarius Qlpqekgg------------lnGkaVYIDtEgTFRwERIe A Sulfolobus_tokodaii Qlplekgg------------lgGkaVYIDtEgTFRwERIe A Aeropyrum_pernix-RADA Qlpedkgg------------leGkaVYVDtEgTFRwERIe A Aeropyrum_pernix-RADA_VAR_OH1 Qlpedkgg------------leGkaVYIDtEgTFRwERIe A Aeropyrum_pernix-RADA_VAR_OH2 Qlpedkgg------------leGkaVYIDtEgTFRwERIe A Aeropyrum_pernix-RADA_VAR_OH3 Qlpedkgg------------leGkaVYIDtEgTFRwERIe A Aeropyrum_pernix-RADA_VAR_TB1 Qlpedkgg------------leGkaVYIDtEgTFRwERIe A Aeropyrum_pernix-RADA_VAR_TB2 Qlpedkgg------------leGkaVYIDtEgTFRwERIe A Aeropyrum_pernix-RADA_VAR_TB6 Qlpedkgg------------leGkaVYIDtEgTFRwERIe ============================================================================ * HUMAN Qlpidrgg------------geGkaMYIDtEgTFRPERLl * S_CEREVISIAE Qipldigg------------geGkCLYIDtEgTFRPvRLv * Apis_mellifera Qlpidmgg------------aeGkCLYIDtEgTFRPERLi * Aspergillus_flavus Qlpfdmgg------------geGkCLYIDtEgTFRPvRLl * Aspergillus_fumigatus Qlpfdmgg------------geGkCLYIDtEgTFRPvRLl * Bovine Qlpidrgg------------geGkaMYIDtEgTFRPERLl * C_elegans Qlpidmgg------------geGkCMYIDtnaTFRPERIi * Candida_albicans Qlpidmgg------------geGkCLYIDtEgTFRPnRLv * Candida_glabrata Qipldlgg------------geGkCLYIDtEgTFRPvRLv * Canis_lupus Qlpidrgg------------geGkaMYIDtEgTFRPERLl * Chaetomium_globosum Qlpfdmgg------------geGkCLYIDtEgTFRPvRLl * Coccidioides_immitis Qlpfdmgg------------geGkCLYIDtEgTFRPvRLl * Coprinus_cinereus Qlpvsmgg------------geGkCLYIDtEgTFRPvRLl * Cricetulus_griseus Qlpidrgg------------geGkaMYIDtEgTFRPERLl * Cryptococcus_neoformans Qlpvsmgg------------geGkCLYIDtEgTFRPvRMl * Danio_rerio Qlpidqgg------------geGkaMYIDtEgTFRPERLl * Debaryomyces_hansenii Qlpidmgg------------geGkCLYIDtEgTFRPvRLv * D_melanogaster Qlpisqkg------------geGkCMYIDtENTFRPERLa * D_pseudoobscura Qlpisqkg------------geGkCLYIDtESTFRtERLs * Emericella_nidulans Qlpfdmgg------------geGkCLYIDtEgTFRPvRLl * Encephalitozoon_cuniculi Qlppeqgg------------ggGkaMYIDtEgTFRsERLv * Eremothecium_gossypii Qipldmgg------------geGkCLYIDtEgTFRPiRLv * Chicken Qlpidrgg------------geGkaMYIDtEgTFRPERLl * Gibberella_zeae Qlpfdmgg------------geGkCMYIDtEgTFRPvRLl * Kluyveromyces_lactis Qipldmgg------------geGkCLYIDtEgTFRPiRLv * Mouse Qlpidrgg------------geGkaMYIDtEgTFRPERLl * Neurospora_crassa Qlpfdmgg------------geGkCLYIDtEgTFRPvRLl * Rabbit Qlpidrgg------------geGkaMYIDtEgTFRPERLl * Pichia_angusta Qlpidngg------------geGkCLYIDtEgTFRPiRLv * Rat Qlpidrgg------------geGkaMYIDtEgTFRPERLl * Schizosaccharomyces_pombe Qlpidmgg------------geGkCLYIDtEgTFRPvRLl * Strongylocentrotus_purpuratus Qlpidngg------------geGkCLYIDtEgTFRPERLi * Tetraodon_nigroviridis Qlpidqgg------------geGkaMYIDtEgTFRPERLl * Tribolium_castaneum Qlalesgg------------geGkCLYIDtEgTFRPERLl * Ustilago_maydis Qlpvdmgg------------geGkCLYIDtENTFRPtRLl * X_tropicalis Qlpidrgg------------geGkaMYIDtEgTFRPERLl * Yarrowia_lipolytica Qlpidqgg------------geGkCLYIDtEgTFRPERLh * X_laevis-RA51A Qlpidrgg------------geGkaMYIDtEgTFRPERLl * X_laevis-RA51B Qlpidrgg------------geGkaMYIDtEgTFRPERLl Cryptosporidium_hominis Qlpvehkg------------geGkCLWIDtEgTFRPERIv Cryptosporidium_parvum Qlpvehkg------------geGkCLWIDtEgTFRPERIv Dictyostelium_discoideum Qlgysqgg------------geGraLYIDtEgTFRPERLl Entamoeba_histolytica Qlgiengg------------teGraIYIDtEgTFRPERLt Leishmania_donovani Qlpisqgg------------aeGmaLYIDtEgTFRPERLv Leishmania_tropica Qlpisqgg------------aeGmaLYIDtEgTFRPERLv Plasmodium_berghei Qlpieqsg------------geGkCLWIDtEgTFRPERIv Plasmodium_falciparum Qlpieqsg------------geGkCLWIDtEgTFRPERIv Tetrahymena_thermophila Qlpkekgg------------geGkaMYIDtEgTFRPERLe Theileria_annulata Qlpveqsg------------geGkCLWVDsEgTFRPERIv Theileria_parva Qlpveqsg------------geGkCLWVDsEgTFRPERIv Trypanosoma_brucei Qlplsqgg------------geGmaLYIDtEgTFRPERLv Trypanosoma_cruzi Qlpisqgg------------aeGmaLYIDtEgTFRPERLv P Arabidopsis_thaliana Qlpmdqgg------------geGkaMYIDaEgTFRPQRLl P Oryza_sativa Qlpldqgg------------geGkaLYIDaEgTFRPQRLl P Maize-R51A1 Qlpldqgg------------geGkaLYIDaEgTFRPQRLl P Maize-R51A2 Qlpldqgg------------geGkaLYIDaEgTFRPQRIl ============================================================================ B E_COLI Qre------------------gktCaFIDaEHaldPiyar B MYCOBACTERIUM_SMEGMATIS Qaa------------------gGiaaFIDaEHaldPEyak B MYCOBACTERIUM_TUBERCULOSIS Qaa------------------gGvaaFIDaEHaldPEyak B Acinetobacter_calcoaceticus Qka------------------gGtCaFIDaEHaldPQyar B Actinobacillus_pleuropneumoniae Qks------------------gktCaFIDaEHaldPvyar B Actinobacillus_succinogenes Qka------------------gkvCaFIDaEHaldPiyaa B Actinomyces_bovis Qaa------------------gGvaaFIDaEHaldPDyar B Azotobacter_vinelandii Qkq------------------gatCaFVDaEHaldPDyaa B Bacillus_clausii Qrn------------------gGqaaFIDaEHaldPvyas B Bacillus_halodurans Qrn------------------gGqaaFIDaEHaldPvyak B Bacillus_licheniformis Qqq------------------gGqaaFIDaEHaldPvyaq B Bacillus_megaterium Qqq------------------gGqaaFIDaEHaldPvyaq B Bacillus_subtilis Qqq-------------------rtsaFIDaEHaldPvyaq B Bordetella_pertussis Qkl------------------gGtCaFVDaEHaldvQyas B Burkholderia_fungorum Qki------------------gGtaaFIDaEHaldiQyas B Chromobacterium_violaceum Qkl------------------gGtCaYIDaENaldPvyaq B Clostridium_acetobutylicum Qkk------------------gGaaaFIDaEHaldPQyar B Clostridium_thermocellum Qka------------------gGeaaFIDaEHaldPvyak B Colwellia_psychrerythraea Qrn------------------gkvCaFIDaEHaldPvyae B Corynebacterium_efficiens Qka------------------gGiaaFIDaEHaldPDyar B Desulfotalea_psychrophila Qkl------------------gGiaaFIDaEHaldtayae B Enterococcus_faecalis Qrn------------------gGtaaFIDaEHaldPQyaz B Haemophilus_ducreyi Qri------------------gktCaFIDaEHaldPvyar B Haemophilus_influenzae Qka------------------gktCaFIDaEHaldPiyaa B Histophilus_somni Qka------------------gktCaFIDaEHaldPiyaa B Kineococcus_radiotolerans Qka------------------gGiaaFIDaEHaldPDyaa B Leifsonia_xyli Qra------------------gGiaaFIDaEHaldPDyar B Mannheimia_succiniciproducens Qka------------------gkvCaFIDaEHaldPiyaa B Nitrosomonas_europaea Qkl------------------gGtaaFIDaEHaldPQyaq B Nitrosomonas_eutropha Qkl------------------gGtaaFIDaEHaldPQyaq B Oceanobacillus_iheyensis Qkq------------------gGqaaFIDaEHaldPvyak B Pasteurella_multocida Qke------------------gktCaFIDaEHaldPiyaa B Photobacterium_profundum Qrv------------------nktCaFIDaEHaldPiyaq B Photorhabdus_luminescens Qre------------------gktCaFIDaEHaldPiyak B Proteus_mirabilis Qre------------------gkiCaFIDaEHaldPiyaq B Pseudomonas_cepacia Qkl------------------gGtaaFIDaEHaldvQyaa B Pseudomonas_pseudomallei Qkl------------------gGtaaFIDaEHaldvQyas B Shewanella_amazonensis Qre------------------gkvCaFIDaEHaldPvyar B Shewanella_putrefaciens Qre------------------gktCaFIDaEHaldPiyak B Streptomyces_avermitilis Qka------------------gGqvaFVDaEHaldPEyak B Vibrio_alginolyticus Qre------------------gktCaFIDaEHaldPvyak B Vibrio_angustum Qrk------------------gktCaFIDaEHaldPiyaq B Vibrio_cholerae Qre------------------gktCaFIDaEHaldPvyak B Vibrio_fischeri Qre------------------gktCaFIDaEHaldPvyak B Vibrio_parahaemolyticus Qre------------------gktCaFIDaEHaldPvyak B Vibrio_splendidus Qrv------------------gktCaFVDaEHaldPiyaq B Vibrio_vulnificus Qre------------------gktCaFIDaEHaldPvyak B Yersinia_enterocolitica Qre------------------gktCaFIDaEHaldPiyak B Cupriavidus_metallidurans-Q1LR74 Qkl------------------gGtCaFIDaEHaldvQyag B Cupriavidus_metallidurans-RECA Qkl------------------gGtCaFIDaEHaldvQyag B Erwinia_carotovora-RECA Qre------------------gkiCaFIDaEHaldPiyaq B Erwinia_carotovora-RECA_ERWCT Qre------------------gktCaFIDaEHaldPiyak B Listeria_monocytogenes-RECA Qaq------------------gGtaaFIDaEHaldPayak B Listeria_monocytogenes-RECA_LISMF Qaq------------------gGtaaFIDaEHaldPayak B Neisseria_gonorrhoeae-RECA Qkn------------------gGvCaFVDaEHaFdPvyar B Neisseria_gonorrhoeae-RECA_VAR Qkn------------------gGvCaFVDaEHaFdPvyar B Salmonella_typhi-RECA Qre------------------gktCaFIDaEHaldPvyar B Salmonella_typhi-RECA_SALPA Qre------------------gktCaFIDaEHaldPvyar B Streptomyces_coelicolor-RECA Qka------------------gGqvaFVDaEHaldPEyak B Streptomyces_coelicolor-RECA_STRL Qka------------------gGqvaFVDaEHaldPEyak B Xylella_fastidiosa-RECA Qkk------------------gGtaaFIDaEHaldPiyag B Xylella_fastidiosa-RECA_XYLFT Qkr------------------gGtaaFIDaEHaldPiyag B Yersinia_pestis-RECA Qre------------------gktCaFIDaEHaldPiyak B Yersinia_pestis-RECA_YERPS Qre------------------gktCaFIDaEHaldPiyak B Mycobacterium_tuberculosis-RECA Qaa------------------gGvaaFIDaEHaldPDyak B Mycobacterium_tuberculosis-RECA_M Qaa------------------gGvaaFIDaEHaldPEyak B Neisseria_meningitidis-RECA Qkn------------------gGvCaFVDaEHaFdPvyar B Neisseria_meningitidis-RECA_NEIMA Qkn------------------gGvCaFVDaEHaFdPvyar B Neisseria_meningitidis-RECA_VAR Qkn------------------gGvCaFVDaEHaFdPvyar B Xanthomonas_vasicola-RECA_XANAC Qkn------------------gGtaaFIDaEHaldPiyaa B Xanthomonas_vasicola-RECA_XANCP Qkl------------------gGtaaFIDaEHaldPiyaa B Xanthomonas_vasicola-YP_201580 Qkl------------------gGtaaFIDaEHaldPvyaa B Pseudomonas_aeruginosa-Q48F94 Qkm------------------gatCaFVDaEHaldPEyag B Pseudomonas_aeruginosa-RECA Qkq------------------gatCaFVDaEHaldPDyag B Pseudomonas_aeruginosa-RECA_PSEF5 Qka------------------gatCaFVDaEHaldPEyag B Pseudomonas_aeruginosa-RECA_PSEFL Qkm------------------gatCaFVDaEHaldPEyag B Pseudomonas_aeruginosa-RECA_PSEPK Qkn------------------gatCaFVDaEHaldPEyag B Pseudomonas_aeruginosa-RECA_PSEPU Qkn------------------gatCaFVDaEHaldPEyag B Pseudomonas_aeruginosa-RECA_PSESM Qkm------------------gatCaFVDaEHaldPEyag ============================================================================ B DEINOCOCCUS_RADIODURANS Qka------------------gGtCaFIDaEHaldPvyar B Deinococcus_geothermalis Qra------------------gGtCaFIDaEHaldPvyar B Thermus_aquaticus-RECA Qkg------------------gGvaaFVDaEHaldPlyak B Thermus_aquaticus-RECA_THET2 Qrr------------------gGvaaFVDaEHaldPlyaq B Thermus_aquaticus-RECA_THET8 Qrr------------------gGvaaFVDaEHaldPlyaq B Thermus_aquaticus-RECA_THETH Qrr------------------gGvaaFVDaEHaldPlyaq ============================================================================ Consensus QxxxxxxxxxxxxxxxxxxxxxgxcvFVDxEntfrPerix 370 380 390 400 ----:----|----:----|----:----|----:----| Consensus qMxxxxxxxxxxxxxxlxxxxxMedIxxxRxxnxDqxlqI ============================================================================ A PYROCOCCUS_FURIOSUS EIaqn---------rgLdpdevLKhIyvaRafNsNhqMlL A Archaeoglobus_fulgidus QMaea---------kgLdgnevLKNIyvaQayNsNhqMlL A Pyrococcus_abyssi EIakn---------rgLdpdevLKhIyvaRafNsNhqMlL ============================================================================ A METHANOCOCCUS_VOLTAE QMaeh---------agIdgqtvLDNtfvaRayNsDmqMlf A Methanococcus_jannaschii QMaea---------lgLdgnevLnNIfvaRayNsDmqMly A Methanococcus_maripaludis QMaeg---------agIdgqtvLDNtfvaRayNsDmqMlf ============================================================================ A SULFOLOBUS_SOLFATARICUS nMaka---------lgLdidnvMnNIyyiRaiNtDhqIaI A Desulfurococcus_amylolyticus aMara---------lgLdpdkvMDNIyymRayNsDhqIaI A Sulfolobus_acidocaldarius aMakg---------agLesdiaMnNIyymRaiNsDhqMaI A Sulfolobus_tokodaii aMska---------igLepdsaMnNIyymRaiNsDhqMaI A Aeropyrum_pernix-RADA QMarg---------vgLdpdevMKNIywiRaiNshhqIaI A Aeropyrum_pernix-RADA_VAR_OH1 QMarg---------vgLdpdevMKNIywiRaiNshhqIaI A Aeropyrum_pernix-RADA_VAR_OH2 QMarg---------vgLdpdevMKNIywiRaiNshhqIaI A Aeropyrum_pernix-RADA_VAR_OH3 QMarg---------vgLdpdevMKNIywiRaiNshhqIaI A Aeropyrum_pernix-RADA_VAR_TB1 QMarg---------vgLdpdevMKNIywiRaiNshhqIaI A Aeropyrum_pernix-RADA_VAR_TB2 QMarg---------vgLdpdevMKNIywiRaiNshhqIaI A Aeropyrum_pernix-RADA_VAR_TB6 QMarg---------vgLdpdevMKNIywiRaiNshhqIaI ============================================================================ * HUMAN aVaer---------ygLsgsdvLDNVayaRafNtDhqtQL * S_CEREVISIAE sIaqr---------fgLdpddaLnNVayaRayNaDhqLRL * Apis_mellifera aVaer---------ykIagdsvLDNVacaRayNtDhqtQL * Aspergillus_flavus aVaqr---------ygLvgeevLDNVayaRayNsDhqLQL * Aspergillus_fumigatus aVaqr---------ygLvgeevLDNVayaRayNsDhqLQL * Bovine aVaer---------ygLsgsdvLDNVayaRgfNtDhqtQL * C_elegans aIaqr---------ynMdsahvLENIavaRayNsEhlMaL * Candida_albicans sIaqr---------ygLnpndcLDNVayaRayNaEhqLnL * Candida_glabrata sIaqr---------fgLdpddaLnNVayaRayNaDhqMRL * Canis_lupus aVaer---------ygLsgsdvLDNVayaRgfNtDhqtQL * Chaetomium_globosum aVanr---------ygLsgeevLDNVayaRayNsDhqLQL * Coccidioides_immitis aVaqr---------ygLageevLDNVayaRayNsDhqLQL * Coprinus_cinereus aVaer---------fgLngeevLDNVayaRayNaDhqqaL * Cricetulus_griseus aVaer---------ygLsgsdvLDNVayaRgfNtDhqtQL * Cryptococcus_neoformans aVaer---------ygLdgeevLDNIayaRayNaDhqLQL * Danio_rerio aVaer---------ygLvgsdvLDNVayaRafNtDhqtQL * Debaryomyces_hansenii sIaqr---------ygLnpedcLDNVayaRayNaEhqfQL * D_melanogaster aIaqr---------ykLnesevLDNVaftRahNsDQqtKL * D_pseudoobscura aIaqr---------fkLnesevLDNVscaRayNsDQqtKL * Emericella_nidulans aVaqr---------ygLvgeevLDNVayaRayNsDhqLQL * Encephalitozoon_cuniculi pIaer---------fgLdpnevMDNIsyaRayNsDhqsQL * Eremothecium_gossypii sIaqr---------fgLdpddaLnNVayaRayNaDhqLRL * Chicken aVaer---------ygLsgsdvLDNVayaRgfNtDhqtQL * Gibberella_zeae gVanr---------fgLsgeevLDNVayaRayNsDhqLQL * Kluyveromyces_lactis sIaqr---------fgLdpddaLnNVayaRayNaDhqLKL * Mouse aVaer---------ygLsgsdvLDNVayaRgfNtDhqtQL * Neurospora_crassa aVanr---------ygLsgeevLDNVayaRayNsDhqLQL * Rabbit aVaer---------ygLsgsdvLDNVayaRgfNtDhqtQL * Pichia_angusta aIarr---------fgLdenetLDNVayaRayNaDhqLQL * Rat aVaer---------ygLsgsdvLDNVayaRgfNtDhqtQL * Schizosaccharomyces_pombe aVadr---------ygLngeevLDNVayaRayNaDhqLEL * Strongylocentrotus_purpuratus aVadr---------ynLsgsdvLDNVayaRahNsDhqsQL * Tetraodon_nigroviridis aVaerrvsgrslavygLvgsdvLDNVayaRafNtDhqtQL * Tribolium_castaneum pVaer---------ynMdgqqvLDNVvfaRafNtDhqtEL * Ustilago_maydis aVaer---------fgLngeevLDNVayaRayNaDhqLQL * X_tropicalis aVaer---------ygLsgsdvLDNVayaRafNtDhqtQL * Yarrowia_lipolytica QIarr---------ygLngdevLDNVayaRahNsDhqMQL * X_laevis-RA51A aVaer---------ygLsgsdvLDNVayaRafNtDhqtQL * X_laevis-RA51B aVaer---------ygLsgsdvLDNVayaRafNtDhqtQL Cryptosporidium_hominis QIadr---------fnLnasdcLDNIayaRgfNtEhqMdL Cryptosporidium_parvum QIadr---------fnLnasdcLDNIayaRgfNtEhqMdL Dictyostelium_discoideum aIaer---------ynLngehvLDNVsyaRayNsDhqLEL Entamoeba_histolytica QIaek---------ygLnseeaLnNVavaRahNtEhqMQL Leishmania_donovani aVaer---------ykLdpedvLaNVacaRafNtDhqqQL Leishmania_tropica aVaer---------ykLdpedvLaNVacaRafNtDhqqQL Plasmodium_berghei aIakr---------ygLhptdcLnNIayaKayNcDhqtEL Plasmodium_falciparum aIakr---------ygLhptdcLnNIayaKayNcDhqtEL Tetrahymena_thermophila sIaer---------fgLdpqecMENVayaRafNcDQqnKL Theileria_annulata sIakr---------fgLspsdcLDNVayaRayNtDhqLEL Theileria_parva sIakr---------fgLspsdcLDNVayaRayNtDhqLEL Trypanosoma_brucei aVaer---------ysLdpeavLENVacaRayNtDhqqQL Trypanosoma_cruzi aVaer---------ykLdpqdvLsNVacaRafNtDhqqQL P Arabidopsis_thaliana QIadr---------fgLngadvLENVayaRayNtDhqsRL P Oryza_sativa QIadr---------fgLngadvLENVayaRayNtDhqsRL P Maize-R51A1 QIadr---------fgLngadvLENVayaRayNtDhqsRL P Maize-R51A2 QIadr---------fgLngadvLENVayaRayNtDhqsRL ============================================================================ B E_COLI KLg---------------v--dIDNLlcsQpdtgEQaLEI B MYCOBACTERIUM_SMEGMATIS KLg---------------v--dtDsLlvsQpdtgEQaLEI B MYCOBACTERIUM_TUBERCULOSIS KLg---------------v--dtDsLlvsQpdtgEQaLEI B Acinetobacter_calcoaceticus KLg---------------v--dIDNLlvsQpdHgEQaLEI B Actinobacillus_pleuropneumoniae KLg---------------v--dtDaLlisQpdNgEQaLEI B Actinobacillus_succinogenes KLg---------------v--dVKELfisQpdNgEQaLEI B Actinomyces_bovis KLg---------------v--dtDaLlvsQpdtgEQaLEI B Azotobacter_vinelandii KLg---------------v--nVDDLlvsQpdtgEQaLEI B Bacillus_clausii KLg---------------v--nIDELllsQpdtgEQaLEI B Bacillus_halodurans KLg---------------v--nIDELllsQpdtgEQaLEI B Bacillus_licheniformis KLg---------------v--nIDELllsQpdtgEQaLEI B Bacillus_megaterium KLg---------------v--nIDELllsQpdtgEQaLEI B Bacillus_subtilis KLg---------------v--nIEELllsQpdtgEQaLEI B Bordetella_pertussis KLg---------------v--nLtDLlisQpdtgEQaLEI B Burkholderia_fungorum KLg---------------v--nVnDLlvsQpdtgEQaLEI B Chromobacterium_violaceum KLg---------------v--nVEDLlisQpdtgEQaLEI B Clostridium_acetobutylicum aLg---------------v--dIDNLvvsQpdtgEQaLEI B Clostridium_thermocellum nLg---------------v--dIENLivsQpdtgEQaLEI B Colwellia_psychrerythraea KLg---------------v--nIDELlisQpdtgEQaLEI B Corynebacterium_efficiens KLg---------------v--dtDaLlvsQpdtgEQaLEI B Desulfotalea_psychrophila KLg---------------v--nIDNLlvsQpdfgEQaLEI B Enterococcus_faecalis KLg---------------v--nIDELllsQpdtgEQgLEI B Haemophilus_ducreyi KLg---------------v--dIDaLlisQpdNgEQaLEI B Haemophilus_influenzae KLg---------------v--dVKELfvsQpdNgEQaLEI B Histophilus_somni KLg---------------v--dVKELlisQpdNgEQaLEI B Kineococcus_radiotolerans KLg---------------v--dtDaLlvsQpdtgEQaLEI B Leifsonia_xyli KLg---------------v--dIDaLlvsQpdtgEQaLEI B Mannheimia_succiniciproducens KLg---------------v--dVKELlvsQpdNgEQaLEI B Nitrosomonas_europaea KIg---------------v--nVQELlisQpdNgEQaLEI B Nitrosomonas_eutropha KIg---------------v--nVQELlisQpdNgEQaLEI B Oceanobacillus_iheyensis aLg---------------v--nIDELllsQpdtgEQaLEI B Pasteurella_multocida KLg---------------v--nVnELlvsQpdNgEQaLEI B Photobacterium_profundum KLg---------------v--dIDqLlvsQpdtgEQaLEI B Photorhabdus_luminescens KLg---------------v--dIDNLlcsQpdtgEQaLEI B Proteus_mirabilis KLg---------------v--dIDNLlcsQpdtgEQaLEI B Pseudomonas_cepacia KLg---------------v--nVpELlisQpdtgEQaLEI B Pseudomonas_pseudomallei KLg---------------v--nVpELlisQpdtgEQaLEI B Shewanella_amazonensis KLg---------------v--dIDNLlcsQpdtgEQaLEI B Shewanella_putrefaciens KLg---------------v--dIDNLlcsQpdtgEQaLEI B Streptomyces_avermitilis KLg---------------v--dIDNLilsQpdNgEQaLEI B Vibrio_alginolyticus KLg---------------v--dIDaLlvsQpdtgEQaLEI B Vibrio_angustum KLg---------------v--dIDqLlvsQpdtgEQaLEI B Vibrio_cholerae KLg---------------v--nIDELlvsQpdtgEQaLEI B Vibrio_fischeri KLg---------------v--nIDELlvsQpdtgEQaLEI B Vibrio_parahaemolyticus KLg---------------v--dIDaLlvsQpdtgEQaLEI B Vibrio_splendidus KLg---------------v--dIDaLlvsQpdtgEQaLEI B Vibrio_vulnificus KLg---------------v--nIDqLlvsQpdtgEQaLEI B Yersinia_enterocolitica KLg---------------v--dIDNLlcsQpdtgEQaLEI B Cupriavidus_metallidurans-Q1LR74 KLg---------------v--dVgNLlisQpdtgEQaLEI B Cupriavidus_metallidurans-RECA KLg---------------v--dVgNLlisQpdtgEQaLEI B Erwinia_carotovora-RECA KLg---------------v--dIDNLlcsQpdtgEQaLEI B Erwinia_carotovora-RECA_ERWCT KLg---------------v--dIDNLlcsQpdtgEQaLEI B Listeria_monocytogenes-RECA nLg---------------v--nIDELllsQpdtgEQaLEI B Listeria_monocytogenes-RECA_LISMF nLg---------------v--nIDELllsQpdtgEQaLEI B Neisseria_gonorrhoeae-RECA KLg---------------v--kVEELylsQpdtgEQaLEI B Neisseria_gonorrhoeae-RECA_VAR KLg---------------v--kVEELylsQpdtgEQaLEI B Salmonella_typhi-RECA KLg---------------v--dIDNLlcsQpdtgEQaLEI B Salmonella_typhi-RECA_SALPA KLg---------------v--dIDNLlcsQpdtgEQaLEI B Streptomyces_coelicolor-RECA KLg---------------v--dIDNLilsQpdNgEQaLEI B Streptomyces_coelicolor-RECA_STRL KLg---------------v--dIDNLilsQpdNgEQaLEI B Xylella_fastidiosa-RECA KLg---------------v--nVDDLllsQpdtgEQaLEI B Xylella_fastidiosa-RECA_XYLFT KLg---------------v--nVDDLllsQpdtgEQaLEI B Yersinia_pestis-RECA KLg---------------v--dIDNLlcsQpdtgEQaLEI B Yersinia_pestis-RECA_YERPS KLg---------------v--dIDNLlcsQpdtgEQaLEI B Mycobacterium_tuberculosis-RECA KLg---------------v--dtDsLlvsQpdtgEQaLEI B Mycobacterium_tuberculosis-RECA_M KLg---------------v--dtDsLlvsQpdtgEQaLEI B Neisseria_meningitidis-RECA KLg---------------v--kVEELylsQpdtgEQaLEI B Neisseria_meningitidis-RECA_NEIMA KLg---------------v--kVEELylsQpdtgEQaLEI B Neisseria_meningitidis-RECA_VAR KLg---------------v--kVEELylsQpdtgEQaLEI B Xanthomonas_vasicola-RECA_XANAC KLg---------------v--nVDDLllsQpdtgEQaLEI B Xanthomonas_vasicola-RECA_XANCP KLg---------------v--nVDDLllsQpdtgEQaLEI B Xanthomonas_vasicola-YP_201580 KLg---------------v--nVDDLllsQpdtgEQaLEI B Pseudomonas_aeruginosa-Q48F94 KLg---------------v--nVDDLlvsQpdtgEQaLEI B Pseudomonas_aeruginosa-RECA KLg---------------v--nVDDLlvsQpdtgEQaLEI B Pseudomonas_aeruginosa-RECA_PSEF5 KLg---------------v--nVDDLlvsQpdtgEQaLEI B Pseudomonas_aeruginosa-RECA_PSEFL KLg---------------v--nVDDLlvsQpdtgEQaLEI B Pseudomonas_aeruginosa-RECA_PSEPK KLg---------------v--nVDDLlvsQpdtgEQaLEI B Pseudomonas_aeruginosa-RECA_PSEPU KLg---------------v--nVDDLlvsQpdtgEQaLEI B Pseudomonas_aeruginosa-RECA_PSESM KLg---------------v--nVDDLlvsQpdtgEQaLEI ============================================================================ B DEINOCOCCUS_RADIODURANS aLg---------------v--ntDELlvsQpdNgEQaLEI B Deinococcus_geothermalis sLg---------------v--ntDELlvsQpdNgEQaLEI B Thermus_aquaticus-RECA KLg---------------v--dVQELlvsQpdtgEQaLEI B Thermus_aquaticus-RECA_THET2 RLg---------------v--qVEDLlvsQpdtgEQaLEI B Thermus_aquaticus-RECA_THET8 RLg---------------v--qVEDLlvsQpdtgEQaLEI B Thermus_aquaticus-RECA_THETH RLg---------------v--qVEDLlvsQpdtgEQaLEI ============================================================================ Consensus qMxxxxxxxxxxxxxxlxxxxxMedIxxxRxxnxDqxlqI 410 420 430 440 ----:----|----:----|----:----|----:----| Consensus vexlxqxxxxxxxxxxxxixLVVVDSvxalfrxefigrdx ============================================================================ A PYROCOCCUS_FURIOSUS VQqaedkik-ellntdrpVkLLIVDSLtshFRsEYIGRga A Archaeoglobus_fulgidus VDnakElae-klkkegrpVrLIIVDSLmshFRaEYVGRgt A Pyrococcus_abyssi VQqaedkik-ellntdkpVkLLIVDSLtshFRsEYIGRga ============================================================================ A METHANOCOCCUS_VOLTAE aEkIedliqegn-----nIkLVVIDSLtstFRnEYtGRgk A Methanococcus_jannaschii aEnVenliregh-----nIkLVIVDSLtstFRtEYIGRgk A Methanococcus_maripaludis aEkIedlikggn-----nIkLVIIDSLtstFRnEFtGRgk ============================================================================ A SULFOLOBUS_SOLFATARICUS VDdLqElvs-kdp----sIkLIVVDSVtshFRaEYpGREn A Desulfurococcus_amylolyticus VDeLftfvp-kn-----dVrLVILDSVtshFRaEYpGREh A Sulfolobus_acidocaldarius VDdLqElit-kdp----aIkLIIVDSItshFRaEYpGREn A Sulfolobus_tokodaii VDdLqElis-kdp----aIkLVIVDSVtshFRaEFpGREn A Aeropyrum_pernix-RADA VDkLftmvk-nd-----nIkLVVVDSVtshFRaEFpGREn A Aeropyrum_pernix-RADA_VAR_OH1 VDkLftmvk-nd-----nIkLVVVDSVtshFRaEFpGREn A Aeropyrum_pernix-RADA_VAR_OH2 VDkLftmvk-nd-----nIrLVVVDSVtshFRaEFpGREn A Aeropyrum_pernix-RADA_VAR_OH3 VDkLftmvk-nd-----nIkLVVVDSVtshFRvEFpGREn A Aeropyrum_pernix-RADA_VAR_TB1 VDkLftmvk-nd-----nIkLVVVDSVtshFRaEFpGREn A Aeropyrum_pernix-RADA_VAR_TB2 VDkLftmvk-nd-----nIkLVVVDSVtshFRaEFpGREn A Aeropyrum_pernix-RADA_VAR_TB6 VDkLftmvk-nd-----nIkLVVVDSVtshFRaEFpGREn ============================================================================ * HUMAN Lyqasammv-es-----ryaLLIVDSatALYRtDYsGR-- * S_CEREVISIAE LDaaaQmms-es-----rfsLIVVDSVmALYRtDFsGR-- * Apis_mellifera Liqasammt-es-----ryaLLIVDSatgLYRtEYsGR-- * Aspergillus_flavus LnqasQmmc-et-----rfsLLVVDSatALYRtDFnGR-- * Aspergillus_fumigatus LnqasQmmc-et-----rfsLLVVDSatsLYRtDFnGR-- * Bovine Lyqasammv-es-----ryaLLIVDSatALYRtDYsGR-- * C_elegans Iiragamms-es-----ryaVVIVDcatAhFRnEYtGR-- * Candida_albicans LniaaEmma-es-----rfsLLIVDSImsLYRtDYaGR-- * Candida_glabrata LDaaaQmms-es-----rfsLIVVDSVmALYRtDFsGR-- * Canis_lupus Lyqasammv-es-----ryaLLIVDSatALYRtDYsGR-- * Chaetomium_globosum Lnqaaammc-et-----rfsLLVVDSatsLYRtDFLGR-- * Coccidioides_immitis LnqasQmmc-et-----rfsLLVVDSatsLYRtDFsGR-- * Coprinus_cinereus Ltsasalms-es-----rfcLLIVDSctALYRtDFsGR-- * Cricetulus_griseus Lyqasammv-es-----ryaLLIVDSatALYRtDYsGR-- * Cryptococcus_neoformans Lvqasamma-es-----rfsLLIVDSctsLYRtDFsGR-- * Danio_rerio Lyqasammt-es-----ryaLLIVDSatALYRtDYsGR-- * Debaryomyces_hansenii LnhaaQmms-es-----rfscLIVDSImsLYRtDYsGR-- * D_melanogaster IQmaagmlf-es-----ryaLLIVDSamALYRsDYIGR-- * D_pseudoobscura LQmaagmlf-et-----ryaaVIVDSVmALYRsDYIGR-- * Emericella_nidulans LnqasQmmc-et-----rfsLLVVDSatsLYRtDFnGR-- * Encephalitozoon_cuniculi Likasamms-es-----kysVLIIDSatALYRtDFsGR-- * Eremothecium_gossypii LDaaaQmms-es-----rfsLIVVDSImALYRtDFsGR-- * Chicken Lyqasamma-es-----ryaLLIVDSatALYRtDYsGR-- * Gibberella_zeae Lnqaaammc-et-----rfsLLIVDSatsLYRtDFcGR-- * Kluyveromyces_lactis LDaaaQmms-es-----rfsLIIVDSImALYRtDFsGR-- * Mouse Lyqasammv-es-----ryaLLIVDSatALYRtDYsGR-- * Neurospora_crassa Lnqaaammc-et-----rfsLLIVDSatsLYRtDFLGR-- * Rabbit Lyqasammv-es-----ryaLLIVDSatALYRtDYsGR-- * Pichia_angusta Lhqaasmmt-es-----rfsLLIVDSImALYRtDYsGR-- * Rat Lyqasammv-es-----ryaLLIVDSatALYRtDYsGR-- * Schizosaccharomyces_pombe LQqaanmms-es-----rfsLLVVDSctALYRtDFsGR-- * Strongylocentrotus_purpuratus Llqasamma-es-----ryaLLIVDSatALYRtDYsGR-- * Tetraodon_nigroviridis Lyqasamma-es-----ryaLLIVDSatALYRtDYsGRvw * Tribolium_castaneum Lvhaaammm-es-----rycLLIVDSatsLYRtDYsGR-- * Ustilago_maydis Lmqasamma-es-----rfsLLIVDSLtsLYRtDFsGR-- * X_tropicalis Lyqasamma-es-----ryaLLIVDSatALYRtDYsGR-- * Yarrowia_lipolytica LQmaanmmt-ks-----rfscLIVDSImALYRtDYaGR-- * X_laevis-RA51A Lyqasamma-es-----ryaLLIVDSatALYRtDYsGR-- * X_laevis-RA51B Lyqasamma-es-----ryaLLIVDSatALYRtDYsGR-- Cryptosporidium_hominis LQsavammt-es-----rfaLMIVDSatALYRsEYnGR-- Cryptosporidium_parvum LQsavammt-es-----rfaLMIVDSatALYRsEYnGR-- Dictyostelium_discoideum Lvqasamms-es-----ryaLLIVDSatALYRtDYaGR-- Entamoeba_histolytica LQmasglma-ke-----rygLLIIDSatALYRtDYsGR-- Leishmania_donovani Llqasamma-en-----rfaLIIVDSatALYRtDYsGR-- Leishmania_tropica Llqasamma-en-----rfaLIIVDSatALYRtDYsGR-- Plasmodium_berghei Lidasamma-dt-----rfaLLIVDSatALYRsEYtGR-- Plasmodium_falciparum Lidasamma-da-----rfaLLIVDSatALYRsEYIGR-- Tetrahymena_thermophila Lvqaaalma-es-----kyaLLIVDSatALYRtDYsGR-- Theileria_annulata Lveasamma-qt-----rfaLLIVDSatsLYRsDYsGR-- Theileria_parva Lveasamma-qt-----rfaLLIVDSatsLYRsDYsGR-- Trypanosoma_brucei Llqasatma-eh-----rVaIIVVDSatALYRtDYnGR-- Trypanosoma_cruzi Llqasamma-en-----rfaIIIVDSatALYRtDYsGR-- P Arabidopsis_thaliana Lleaasmmi-et-----rfaLLIVDSatALYRtDFsGR-- P Oryza_sativa Lleaasmmi-et-----rfaLMIVDSatALYRtDFsGR-- P Maize-R51A1 Lleaasmmi-et-----rfaLMVVDSatALYRtDFsGR-- P Maize-R51A2 Lleaasmmv-et-----rfaLMVVDSatALYRtDFsGR-- ============================================================================ B E_COLI cDaLaR-sg--a------VdVIVVDSVaALtpkaeIegEi B MYCOBACTERIUM_SMEGMATIS aDmLvR-sg--a------LdIIVIDSVaALvpraeIegEm B MYCOBACTERIUM_TUBERCULOSIS aDmLiR-sg--a------LdIVLIDSVaALvpraeLegEm B Acinetobacter_calcoaceticus aDmLvR-sg--a------IdLIVVDSVaALtpkaeIegEm B Actinobacillus_pleuropneumoniae cDaLvR-sg--a------VdVIIVDSVaALtpkaeIegDm B Actinobacillus_succinogenes cDaLvR-sg--a------IdVIIVDSVaALtpkaeIegDm B Actinomyces_bovis aDmLvR-sg--a------IdIIVIDSVaALvpraeIegEm B Azotobacter_vinelandii tDmLvR-sn--a------VdVIIVDSVaALvpkaeIegEm B Bacillus_clausii aEaLvR-sg--a------LdIIVIDSVaALvpkaeIegEm B Bacillus_halodurans aEaLvR-sg--a------IdVIVIDSVaALvpkaeIegEm B Bacillus_licheniformis aEaLvR-sg--a------VdIVVIDSVaALvpkaeIegDm B Bacillus_megaterium aEaLvR-sg--a------VdIIVVDSVaALvpkaeIegEm B Bacillus_subtilis aEaLvR-sg--a------VdIVVVDSVaALvpkaeIegDm B Bordetella_pertussis tDaLvR-sg--s------VdLIVIDSVaALvpkaeIegEm B Burkholderia_fungorum aDaLvR-sg--s------IdMIVIDSVaALvpkaeIegEm B Chromobacterium_violaceum cDmLvR-ss--g------VdVIVVDSVaALvpkaeIegEm B Clostridium_acetobutylicum aEaLvR-sg--a------IdVIVVDSVaALvpkaeIegEm B Clostridium_thermocellum aEaLvR-sg--a------IdVIVIDSVaALvpkaeIdgEm B Colwellia_psychrerythraea VDmLtR-sg--a------IdVIVVDSVaALtpkaeIegDm B Corynebacterium_efficiens aDmLvR-sg--a------IdILVIDSVaALtpkaeIegEm B Desulfotalea_psychrophila aEiLiR-sg--g------VdIIVVDSVaALtpkaeIdgNv B Enterococcus_faecalis aDaLvs-sg--a------IdIVVIDSVaALvpraeIdgEm B Haemophilus_ducreyi cDaLvR-sg--a------VdVIIVDSVaALtpkaeIegDm B Haemophilus_influenzae cDaLvR-sg--a------IdVIIVDSVaALtpkaeIegDm B Histophilus_somni cDaLvR-sg--a------VdVVIVDSVaALtpkaeIegEm B Kineococcus_radiotolerans aDmLiR-sg--a------LdIIVIDSVaALvpkaeIegEm B Leifsonia_xyli aDmLvR-sg--s------IdLIVIDSVaALvpraeIegEm B Mannheimia_succiniciproducens cDaLvR-sg--a------VdVIIVDSVaALtpkaeIegDm B Nitrosomonas_europaea tDmLvR-sg--s------VdVVVVDSVaALtpraeIegEm B Nitrosomonas_eutropha tDmLvR-sg--s------VdIVVIDSVaALtpraeIegEm B Oceanobacillus_iheyensis aEaLvR-sg--a------VdIIVVDSVaALvpkaeIegEm B Pasteurella_multocida cDaLvR-sg--a------VdVIIVDSVaALtpkaeIegEm B Photobacterium_profundum cDaLaR-sg--a------VdLIVIDSVaALtpkaeIegEm B Photorhabdus_luminescens cDaLtR-sg--a------VdVIIVDSVaALtpkaeIegEi B Proteus_mirabilis cDaLsR-sg--a------VdVIVVDSVaALtpkaeIegEi B Pseudomonas_cepacia tDaLvR-sg--s------IdMIVIDSVaALvpkaeIegEm B Pseudomonas_pseudomallei VDaLvR-sg--s------IdMIVIDSVaALvpkaeIegEm B Shewanella_amazonensis cDaLtR-sg--a------VdVIIVDSVaALvpkaeIegEi B Shewanella_putrefaciens cDaLtR-sg--a------VdVIIVDSVaALtpkaeIegEi B Streptomyces_avermitilis VDmLvR-sg--a------LdLIVIDSVaALvpraeIegEm B Vibrio_alginolyticus cDaLaR-sg--a------IdVMVVDSVaALtpkaeIegEm B Vibrio_angustum cDaLaR-sg--a------VdLIVVDSVaALtpkaeIegEm B Vibrio_cholerae cDaLaR-sg--a------VdVIVVDSVaALtpkaeIegEm B Vibrio_fischeri cDaLaR-sg--a------VdVMVIDSVaALtpkaeIegEm B Vibrio_parahaemolyticus cDaLaR-sg--a------IdVMVVDSVaALtpkaeIegEm B Vibrio_splendidus cDaLaR-sg--a------IdVLVIDSVaALtpkaeIegEm B Vibrio_vulnificus cDaLaR-sg--a------VdVIVVDSVaALtpkaeIegEm B Yersinia_enterocolitica cDaLtR-sg--a------VdVIIVDSVaALtpkaeIegEi B Cupriavidus_metallidurans-Q1LR74 tDaLvR-sg--s------IdLIVIDSVaALvpkaeIegEm B Cupriavidus_metallidurans-RECA tDaLvR-sg--s------IdLIVIDSVaALvpkaeIegEm B Erwinia_carotovora-RECA cDaLsR-sg--a------VdVIVVDSVaALtpkaeIegEi B Erwinia_carotovora-RECA_ERWCT cDaLtR-sg--a------VdVIIVDSVaALtpkaeIegEi B Listeria_monocytogenes-RECA aEaLvR-sg--a------VdMLVIDSVaALvpraeIegEm B Listeria_monocytogenes-RECA_LISMF aEaLvR-sg--a------VdMLVIDSVaALvpraeIegEm B Neisseria_gonorrhoeae-RECA cDtLvR-sg--g------IdMVVVDSVaALvpkaeIegDm B Neisseria_gonorrhoeae-RECA_VAR cDtLvR-sg--g------IdMVVVDSVaALvpkaeIegDm B Salmonella_typhi-RECA cDaLaR-sg--a------VdVIVVDSVaALtpkaeIegEi B Salmonella_typhi-RECA_SALPA cDaLaR-sg--a------VdVIVVDSVaALtpkaeIegEi B Streptomyces_coelicolor-RECA VDmLvR-sg--a------LdLIVIDSVaALvpraeIegEm B Streptomyces_coelicolor-RECA_STRL VDmLvR-sg--a------LdLIVIDSVaALvpraeIegEm B Xylella_fastidiosa-RECA aDmLvR-sg--s------IdIMVIDSVaALtpraeIegEm B Xylella_fastidiosa-RECA_XYLFT aDmLvR-sg--s------IdIMVIDSVaALtpraeIegEm B Yersinia_pestis-RECA cDaLtR-sg--a------VdVIIVDSVaALtpkaeIegEi B Yersinia_pestis-RECA_YERPS cDaLtR-sg--a------VdVIIVDSVaALtpkaeIegEi B Mycobacterium_tuberculosis-RECA aDmLiR-sg--a------LdIVVIDSVaALvpraeLegEm B Mycobacterium_tuberculosis-RECA_M aDmLiR-sg--a------LdILVIDSVaALvpraeLegEm B Neisseria_meningitidis-RECA cDtLvR-sg--g------IdMVVVDSVaALvpkaeIegDm B Neisseria_meningitidis-RECA_NEIMA cDtLvR-sg--g------IdMVVVDSVaALvpkaeIegDm B Neisseria_meningitidis-RECA_VAR cDtLvR-sg--g------VdMVVVDSVaALvpkaeIegDm B Xanthomonas_vasicola-RECA_XANAC aDmLvR-sg--s------VdIVVVDSVaALtpkaeIegEm B Xanthomonas_vasicola-RECA_XANCP aDmLvR-ss--s------VdIVVIDSVaALtpkaeIegEm B Xanthomonas_vasicola-YP_201580 aDmLvR-ss--s------VdIVVIDSVaALtpkaeIegEm B Pseudomonas_aeruginosa-Q48F94 tDmLvR-sn--a------IdVIVVDSVaALvpkaeIegEm B Pseudomonas_aeruginosa-RECA tDmLvR-sn--a------VdVIIVDSVaALvpkaeIegEm B Pseudomonas_aeruginosa-RECA_PSEF5 tDmLvR-sn--a------VdVIIVDSVaALvpkaeIegEm B Pseudomonas_aeruginosa-RECA_PSEFL tDmLvR-sn--a------IdVIVVDSVaALvpkaeIegEm B Pseudomonas_aeruginosa-RECA_PSEPK tDmLvR-sn--a------VdVIIVDSVaALvpkaeIegEm B Pseudomonas_aeruginosa-RECA_PSEPU tDmLvR-sn--a------VdVIIVDSVaALvpkaeIegEm B Pseudomonas_aeruginosa-RECA_PSESM tDmLvR-sn--a------IdVIVVDSVaALvpkaeIegEm ============================================================================ B DEINOCOCCUS_RADIODURANS MElLvR-sg--a------IdVVVVDSVaALtpraeIegDm B Deinococcus_geothermalis MElLvR-sg--a------IdVVVVDSVaALtpraeIegEm B Thermus_aquaticus-RECA VElLaR-sg--a------VdVIVVDSVaALvpkaeIegEm B Thermus_aquaticus-RECA_THET2 VElLaR-sg--a------VdVIVVDSVaALvpraeIegEm B Thermus_aquaticus-RECA_THET8 VElLaR-sg--a------VdVIVVDSVaALvpraeIegEm B Thermus_aquaticus-RECA_THETH VElLaR-sg--a------VdVIVVDSVaALvpgaeIegEm ============================================================================ Consensus vexlxqxxxxxxxxxxxxixLVVVDSvxalfrxefigrdx 450 460 470 480 ----:----|----:----|----:----|----:----| Consensus gexnxxmRqqxxxLsQxLRqLxxlxeqxxxxvIxxNqixx ============================================================================ A PYROCOCCUS_FURIOSUS la----eRQQ--kLaKhLadLhrLanlydiaVfvtNQVqa A Archaeoglobus_fulgidus la----dRQQ--kLNRhLhdLmkfgElynaaIVvtNQVma A Pyrococcus_abyssi la----eRQQ--kLaKhLadLhrLanlyeiaVfvtNQVqa ============================================================================ A METHANOCOCCUS_VOLTAE la----eRQQ--kLgRhMatLnkLaDlfncvVLvtNQVsa A Methanococcus_jannaschii la----eRQQ--kLgRhMatLnkLaDiyncvVIvtNQVaa A Methanococcus_maripaludis la----eRQQ--kLgRhMatLnkLaDlynciVLvtNQVaa ============================================================================ A SULFOLOBUS_SOLFATARICUS la----VRQQ--kLNKhLhQLtrLaEvydiaVIitNQVma A Desulfurococcus_amylolyticus la----eRQQ--kLNshLhQLmrLaEaynvaVVvtNQVma A Sulfolobus_acidocaldarius la----VRQQ--kLNKhLhQLvrLaEmydiaVIitNQVma A Sulfolobus_tokodaii la----VRQQ--kLNKhLhQLvrLaEmydlaVIitNQVma A Aeropyrum_pernix-RADA la----MRQQ--lLNRhLhQLmrLaDifnvaVVitNQVma A Aeropyrum_pernix-RADA_VAR_OH1 la----MRQQ--lLNRhLhQLmrLaDifnvaVVitNQVma A Aeropyrum_pernix-RADA_VAR_OH2 la----MRQQ--lLNRhLhQLmrLaDifnvaVVitNQVma A Aeropyrum_pernix-RADA_VAR_OH3 la----MRQQ--lLNRhLhQLmrLaDifnvaVVitNQVma A Aeropyrum_pernix-RADA_VAR_TB1 la----MRQQ--lLNRhLhQLmrLaDifnvaVVitNQVma A Aeropyrum_pernix-RADA_VAR_TB2 la----MRQQ--lLNRhLhQLmrLaDifnvaVVitNQVma A Aeropyrum_pernix-RADA_VAR_TB6 la----MRQQ--lLNRhLhQLmrLaDifnvaVVitNQVma ============================================================================ * HUMAN GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * S_CEREVISIAE GElS--aRQm--hLaKfMRaLqrLaDQfgvaVVvtNQVva * Apis_mellifera GEla--aRQm--hLgRfLRmLlrLaDEhgvaVVitNQVva * Aspergillus_flavus GElS--tRQt--hLaKfMRtLqrLaDEfgiaVVitNQVva * Aspergillus_fumigatus GElS--sRQt--hLaKfMRtLqrLaDEfgiaVVitNQVva * Bovine GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * C_elegans GDla--eRQm--kLSafLKcLakLaDEygvaVIitNQVva * Candida_albicans GElS--aRQt--hVaKfMRtLqrLaDEfgiaVVitNQVva * Candida_glabrata GElS--aRQm--hLaKfMRaLqrLaDQfgvaVVvtNQVva * Canis_lupus GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * Chaetomium_globosum GElN--sRQt--hLaKfLRtLqrLaDEfgiaVVitNQVva * Coccidioides_immitis GElS--sRQt--hLaRfMRtLqrLaDEfgvaVVitNQVva * Coprinus_cinereus GElS--sRQt--hLgKfLRtLqrLaDEfgiaVVvtNQVms * Cricetulus_griseus GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * Cryptococcus_neoformans GElS--aRQm--hLaKfLRtLmrLaDEfgvaVVvtNQVva * Danio_rerio GElS--aRQg--hLgRfLRmLlrLaDEfgvaVVitNQVva * Debaryomyces_hansenii aElS--aRQt--hVaKyMRtLqrLaDEfgiaVVitNQVva * D_melanogaster GEla--aRQn--hLglfLRmLqrLaDEfgvaVVitNQVta * D_pseudoobscura GEla--aRQn--hLglcMRQLqrLaDEfgvaVVitNQVta * Emericella_nidulans GElS--tRQt--hLaKfMRtLqrLaDEfgiaVVitNQVva * Encephalitozoon_cuniculi GElg--aRQl--hLaKyLRsLvnLaEtfriaVIitNQVvs * Eremothecium_gossypii GElS--aRQm--hLaKfMRaLqrLaDQfgvaVVvtNQVva * Chicken GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * Gibberella_zeae GElS--nRQt--hLaKfMRtLqrLaDEfgiaVVitNQVva * Kluyveromyces_lactis GElS--aRQm--hLaKfMRsLqrLaDQfgvaaVvtNQVva * Mouse GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * Neurospora_crassa GElS--sRQt--hLaKfMRtLqrLaDEfgiaVVitNQVva * Rabbit GElS--aRQm--hLaRfLRmLlrLaDEfgvtVVitNQVva * Pichia_angusta GElS--aRQm--hVaKfMRtLqrLaDEfgiaVVitNQVva * Rat GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * Schizosaccharomyces_pombe GElS--aRQm--hLaRfMRtLqrLaDEfgiaVVitNQVva * Strongylocentrotus_purpuratus GEla--sRQm--hLgRfLRtLlrLaDEygvaVVitNQVva * Tetraodon_nigroviridis rrcg--dnQsgggtgRrgRhVfrrsQEthwrqhsgSRfyh * Tribolium_castaneum GElS--aRQn--hLaRfLRmLlrLaDEfgvaVVltNQVva * Ustilago_maydis GElS--aRQm--hLaKfLRgLmrLaDEfgvaVVitNQVva * X_tropicalis GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * Yarrowia_lipolytica GElS--aRQt--hVaKfMRtLqrLaDEfgiaVVitNQVva * X_laevis-RA51A GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva * X_laevis-RA51B GElS--aRQm--hLaRfLRmLlrLaDEfgvaVVitNQVva Cryptosporidium_hominis GEla--tRQs--hLgQfLRaLqkIaDtfgvaVVitNQVms Cryptosporidium_parvum GEla--tRQs--hLgQfLRaLqkIaDtfgvaVVitNQVms Dictyostelium_discoideum GEla--dRQK--hLaRfLRtLqrLaDEfgvaVVitNQVva Entamoeba_histolytica GEla--sRQm--hLaKfLRaLqrIaDEfsvaVVltNQVva Leishmania_donovani nEla--aRQm--hLgKfLRsLhnLaEEygvaVVvtNQVva Leishmania_tropica nEla--aRQm--hLgKfLRsLhnLaEEygvaVVvtNQVva Plasmodium_berghei GEla--nRQs--hLcRfLRgLqrIaDiygvaVIitNQVva Plasmodium_falciparum GEla--nRQs--hLcRfLRgLqrIaDiygvaVIitNQVva Tetrahymena_thermophila GElS--VRQn--hLgKfLRnLqrLaDEfgiaVVitNQVms Theileria_annulata GEla--sRQm--hLcKfLRaLqrIaDtfgvaVVitNQVva Theileria_parva GEla--sRQm--hLcKfLRaLqrIaDtfgvaVVitNQVva Trypanosoma_brucei GEla--aRQm--hLgKfLRsLrnLanEynvaVVvtNQVva Trypanosoma_cruzi nEla--aRQm--hLgKfLRsLhnLaEEygvaVVvtNQVva P Arabidopsis_thaliana GElS--aRQm--hLaKfLRsLqkLaDEfgvaVVitNQVva P Oryza_sativa GElS--aRQm--hMaKfLRsLqkLaDEfgvaVVitNQVva P Maize-R51A1 GElS--aRQm--hMaKfLRsLqkLaDEfgvaVVitNQVva P Maize-R51A2 GElS--aRQm--hLaKfLRsLqkLaDEfgvaVVitNQVva ============================================================================ B E_COLI GDsHmgLaaR--mMSQaMRKLagnlKQsntlLIfiNQIrm B MYCOBACTERIUM_SMEGMATIS GDsHvgLQaR--lMSQaLRKMtgalnnsgttaIfiNQLre B MYCOBACTERIUM_TUBERCULOSIS GDsHvgLQaR--lMSQaLRKMtgalnnsgttaIfiNQLre B Acinetobacter_calcoaceticus GDsHmgLQaR--lMSQaLRKItgnaKRsncmVIfiNQIrm B Actinobacillus_pleuropneumoniae GDsHmgLQaR--lMSQaLRKLtaniKatnclVVfiNQIrm B Actinobacillus_succinogenes GDaHvgLQaR--lMSQaLRKLtaqiKssnclVVfiNQIrm B Actinomyces_bovis GDsHvgLQaR--lMSQaLRKMtsalnnsgttaIfiNQLre B Azotobacter_vinelandii GDqHvgLQaR--lMSQaLRKItgniQnanclVIfiNQIrm B Bacillus_clausii GDsHvgLQaR--lMSQaLRKLsgainKsktiaIfiNQIre B Bacillus_halodurans GDsHvgLQaR--lMSQaLRKLsgainKsktiaIfiNQIre B Bacillus_licheniformis GDsHvgLQaR--lMSQaLRKLsgainKsktiaIfiNQIre B Bacillus_megaterium GDsHvgLQaR--lMSQaLRKLsgainKsktiaIfiNQIre B Bacillus_subtilis GDsHvgLQaR--lMSQaLRKLsgainKsktiaIfiNQIre B Bordetella_pertussis GDslpgLQaR--lMSQaLRKLtatiKRtncmVIfiNQIrm B Burkholderia_fungorum GDslpgLQaR--lMSQaLRKLtgtiKRtnclVIfiNQIrm B Chromobacterium_violaceum GDsHvgLQaR--lMSQaLRKLtgniKRtntlVIfiNQIrm B Clostridium_acetobutylicum GDsHvgLQaR--lMSQaLRKLtgsinKskciaIfiNQLre B Clostridium_thermocellum GDsHvgLQaR--lMSQaLRKLagVinKsrttaIfiNQLre B Colwellia_psychrerythraea GDsHmgLQaR--mLSQaMRKLtgnlKKsntmLIfiNQIrm B Corynebacterium_efficiens GDsHvgLQaR--lMSQaLRKMtgalynsgttaIfiNQLre B Desulfotalea_psychrophila GDvHvgLQaR--lMSQaMRKfagVlnRsntvLIfiNQIrm B Enterococcus_faecalis GasHvgLQaR--lMSQaLRKLsgsinKtktiaIfiNQIre B Haemophilus_ducreyi GDsymgLQaR--lMSQaLRKLtaniKatnclVVfiNQIrm B Haemophilus_influenzae GDsHmgLQaR--lMSQaLRKLtgqiKnanclVVfiNQIrm B Histophilus_somni GDtHvgLQaR--lMSQaLRKLtgqiKnsnclVVfiNQIrm B Kineococcus_radiotolerans GDsHvgLQaR--lMSQaLRKItgalnhsgttaIfiNQLre B Leifsonia_xyli GDaHvgLQaR--lMSQaLRKLtgalsQtnttMIfiNQLre B Mannheimia_succiniciproducens GDsHvgLQaR--lMSQaLRKLtgqiKnanclVVfiNQIrm B Nitrosomonas_europaea GEpqmgLQaR--lMSQaLRKLtaniKRtntmVIfiNQIrm B Nitrosomonas_eutropha GEpqmgLQaR--lMSQaLRKLtaniKRtnttVIfiNQIrm B Oceanobacillus_iheyensis GDsHvgLQaR--lMSQaLRKLsgainKskttaIfiNQIre B Pasteurella_multocida GDsHmgLQaR--lMSQaLRKLtgqiKnsnclVVfiNQIrm B Photobacterium_profundum GDsHmgLQaR--mLSQaMRKLtgnlKQsncmcIfiNQIrm B Photorhabdus_luminescens GDsHmgLaaR--mMSQaMRKLagnlKssntlLIfiNQIrm B Proteus_mirabilis GDsHvgLaaR--mMSQaMRKLagnlKnsntlLIfiNQIrm B Pseudomonas_cepacia GDslpgLQaR--lMSQaLRKLtgtiKRtnclVIfiNQIrm B Pseudomonas_pseudomallei GDalpgLQaR--lMSQaLRKLtgtiKRtnclVIfiNQIrm B Shewanella_amazonensis GDsHvgLaaR--mMSQaMRKLagnlKQsntlLIfiNQIrm B Shewanella_putrefaciens GDsHmgLaaR--mMSQaMRKLagnlKQsntlLIfiNQIrm B Streptomyces_avermitilis GDsHvgLQaR--lMSQaLRKItsalnQskttaIfiNQLre B Vibrio_alginolyticus GDsHmgLQaR--mLSQaMRKLtgnlKQsncmcIfiNQIrm B Vibrio_angustum GDsHmgLQaR--mLSQaMRKLtgnlKQsncmcIfiNQIrm B Vibrio_cholerae GDsHmgLQaR--mLSQaMRKLtgnlKQsncmcIfiNQIrm B Vibrio_fischeri GDsHmgLQaR--mLSQaMRKLtgnlKQsncmaIfiNQIrm B Vibrio_parahaemolyticus GDsHmgLQaR--mLSQaMRKLtgnlKQsncmcIfiNQIrm B Vibrio_splendidus GDsHmgLQaR--mLSQaMRKLtgnlKQsncmaIfiNQIrm B Vibrio_vulnificus GDsHmgLQaR--mLSQaMRKLtgnlKQsncmcIfiNQIrm B Yersinia_enterocolitica GDsHmgLaaR--mMSQaMRKLagnlKnantlLIfiNQIrm B Cupriavidus_metallidurans-Q1LR74 GDslpgLQaR--lMSQaLRKLtgtiKRtnclVIfiNQIrm B Cupriavidus_metallidurans-RECA GDslpgLQaR--lMSQgLRKLtgtiKRtnclVIfiNQIrm B Erwinia_carotovora-RECA GDsHvgLaaR--mMSQaMRKLagnlKnsntlLIfiNQIrm B Erwinia_carotovora-RECA_ERWCT GDsHmgLaaR--mMSQaMRKLagnlKQantlLIfiNQIrm B Listeria_monocytogenes-RECA GDaHvgLQaR--lMSQaLRKLsgVinKsktiaIfiNQIre B Listeria_monocytogenes-RECA_LISMF GDaHvgLQaR--lMSQaLRKLsgVinKsktiaIfiNQIre B Neisseria_gonorrhoeae-RECA GDsHvgLQaR--lMSQaLRKLtghiKKtntlVVfiNQIrm B Neisseria_gonorrhoeae-RECA_VAR GDsHvgLQaR--lMSQaLRKLtghiKKtntlVVfiNQIrm B Salmonella_typhi-RECA GDsHmgLaaR--mMSQaMRKLagnlKQsntlLIfiNQIrm B Salmonella_typhi-RECA_SALPA GDsHmgLaaR--mMSQaMRKLagnlKQsntlLIfiNQIrm B Streptomyces_coelicolor-RECA GDsHvgLQaR--lMSQaLRKItsalnQskttaIfiNQLre B Streptomyces_coelicolor-RECA_STRL GDsHvgLQaR--lMSQaLRKItsalnQskttaIfiNQLre B Xylella_fastidiosa-RECA GDqlpgLQaR--lMSQaLRKLtgniKRsntlVIfiNQLrm B Xylella_fastidiosa-RECA_XYLFT GDqlpgLQaR--lMSQaLRKLtgniKRsntlVIfiNQLrm B Yersinia_pestis-RECA GDsHmgLaaR--mMSQaMRKLagnlKnantlLIfiNQIrm B Yersinia_pestis-RECA_YERPS GDsHmgLaaR--mMSQaMRKLagnlKnantlLIfiNQIrm B Mycobacterium_tuberculosis-RECA GDsHvgLQaR--lMSQaLRKMtgalnnsgttaIfiNQLrd B Mycobacterium_tuberculosis-RECA_M GDsHvgLQaR--lMSQaLRKMtgalnnsgttaIfiNQLre B Neisseria_meningitidis-RECA GDsHvgLQaR--lMSQaLRKLtghiKKtntlVVfiNQIrm B Neisseria_meningitidis-RECA_NEIMA GDsHvgLQaR--lMSQaLRKLtghiKKtntlVVfiNQIrm B Neisseria_meningitidis-RECA_VAR GDsHvgLQaR--lMSQaLRKLtghiKKtntlVVfiNQIrm B Xanthomonas_vasicola-RECA_XANAC GDqlpgLQaR--lMSQaLRKLtgniKRsntlVVfiNQLrm B Xanthomonas_vasicola-RECA_XANCP GDqlpgLQaR--lMSQaLRKLtgniKRsntlVVfiNQLrm B Xanthomonas_vasicola-YP_201580 GDqlpgLQaR--lMSQaLRKLtgniKRsntlVVfiNQLrm B Pseudomonas_aeruginosa-Q48F94 GDmHvgLQaR--lMSQaLRKItgniKnanclVIfiNQIrm B Pseudomonas_aeruginosa-RECA GDaHvgLQaR--lMSQaLRKItgniKnanclVIfiNQIrm B Pseudomonas_aeruginosa-RECA_PSEF5 GDmHvgLQaR--lMSQaLRKItgniKnanclVIfiNQIrm B Pseudomonas_aeruginosa-RECA_PSEFL GDmHvgLQaR--lMSQaLRKItgniKnanclVIfiNQIrm B Pseudomonas_aeruginosa-RECA_PSEPK GDmHvgLQaR--lMSQaLRKItgniKnanclVIfiNQIrm B Pseudomonas_aeruginosa-RECA_PSEPU GDmHvgLQaR--lMSQaLRKItgniKnanclVIfiNQIrm B Pseudomonas_aeruginosa-RECA_PSESM GDmHvgLQaR--lMSQaLRKItgniKnanclVIfiNQIrm ============================================================================ B DEINOCOCCUS_RADIODURANS GDslpgLQaR--lMSQaLRKLtaIlsKtgtaaIfiNQVre B Deinococcus_geothermalis GDslpgLQaR--lMSQaLRKLtaIlsKtgtaaIfiNQVre B Thermus_aquaticus-RECA GDqHvgLQaR--lMSQaLRKLtaVlsKsntaaIfiNQVre B Thermus_aquaticus-RECA_THET2 GDqHvgLQaR--lMSQaLRKLtaVlaKsntaaIfiNQVre B Thermus_aquaticus-RECA_THET8 GDqHvgLQaR--lMSQaLRKLtaVlaKsntaaIfiNQVre B Thermus_aquaticus-RECA_THETH GDqHvgLQaR--lMSQaLRKLtaVlaKsntaaIfiNQVre ============================================================================ Consensus gexnxxmRqqxxxLsQxLRqLxxlxeqxxxxvIxxNqixx 490 500 510 520 ----:----|----:----|----:----|----:----| Consensus kixvxfgxxsxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS RpdafFGdpTrpigghilahsa------------------ A Archaeoglobus_fulgidus RpdVlFGdpTkpvgghivahta------------------ A Pyrococcus_abyssi RpdafFGdpTrpigghilahsa------------------ ============================================================================ A METHANOCOCCUS_VOLTAE KpdafFGmaeqaigghivghaa------------------ A Methanococcus_jannaschii RpdalFGpseqaigghivghaa------------------ A Methanococcus_maripaludis KpdayFGvaeqaigghvvghaa------------------ ============================================================================ A SULFOLOBUS_SOLFATARICUS RpdMfYGdpTvavgghtlyhvp------------------ A Desulfurococcus_amylolyticus RpdVfYGdpTtavgghvlahtp------------------ A Sulfolobus_acidocaldarius RpdMfYGdpTtavgghtlyhvp------------------ A Sulfolobus_tokodaii RpdMfYGdpTvavgghtlyhvp------------------ A Aeropyrum_pernix-RADA RpdVfYGdpTqavgghvlghap------------------ A Aeropyrum_pernix-RADA_VAR_OH1 RpdVfYGdpTqavgghvlghap------------------ A Aeropyrum_pernix-RADA_VAR_OH2 RpdVfYGdpTqavgghvlghap------------------ A Aeropyrum_pernix-RADA_VAR_OH3 RpdVfYGdpTqavgghvlghap------------------ A Aeropyrum_pernix-RADA_VAR_TB1 RpdVfYGdpTqavgghvlghap------------------ A Aeropyrum_pernix-RADA_VAR_TB2 RpdVfYGdpTqavgghvlghap------------------ A Aeropyrum_pernix-RADA_VAR_TB6 RpdVfYGdpTqavgghvlghap------------------ ============================================================================ * HUMAN QVd-g--a-a--------------------------m-fa * S_CEREVISIAE QVd-g--g-m--------------------------a-fn * Apis_mellifera QVd-g--a-a--------------------------smfg * Aspergillus_flavus QVd-ggps-a--------------------------m-fn * Aspergillus_fumigatus QVd-ggps-a--------------------------m-fn * Bovine QVd-g--a-a--------------------------m-fa * C_elegans QVdgg--a-S--------------------------m-fq * Candida_albicans QVd-g-ms-g--------------------------m-fn * Candida_glabrata QVd-g--g-m--------------------------s-fn * Canis_lupus QVd-g--a-a--------------------------m-fa * Chaetomium_globosum QVd-ggps-a--------------------------m-fn * Coccidioides_immitis QVe-ggps-a--------------------------m-fn * Coprinus_cinereus tpd-a--apg--------------------------p-ya * Cricetulus_griseus QVd-g--a-a--------------------------m-ft * Cryptococcus_neoformans QVd-g--g-q--------------------------f-av * Danio_rerio QVd-g--a-a--------------------------m-fs * Debaryomyces_hansenii QVd-g--asa--------------------------m-fn * D_melanogaster sLd-g--a-p--------------------------g-mf * D_pseudoobscura QLdgg--g-g--------------------------m-fv * Emericella_nidulans QVd-ggps-a--------------------------m-fn * Encephalitozoon_cuniculi nVd-g--avg--------------------------m-ft * Eremothecium_gossypii QVd-g--a-a--------------------------m-fn * Chicken QVd-g--a-a--------------------------m-fa * Gibberella_zeae QVd-ggps-a--------------------------m-fn * Kluyveromyces_lactis QVd-g--g-m--------------------------m-fn * Mouse QVd-g--a-a--------------------------m-fa * Neurospora_crassa QVd-ggps-a--------------------------m-fn * Rabbit QVd-g--a-a--------------------------m-fa * Pichia_angusta QVd-g--g-a--------------------------i-fn * Rat QVd-g--a-a--------------------------m-fa * Schizosaccharomyces_pombe QVd-g--i-S----------------------------fn * Strongylocentrotus_purpuratus QVd-g--a-a--------------------------m-ft * Tetraodon_nigroviridis pVs-g--v-f--------------------------k-tc * Tribolium_castaneum QVd-g--a-a--------------------------m-fn * Ustilago_maydis QVd-g--a-T--------------------------a-ft * X_tropicalis QVd-g--a-a--------------------------m-fa * Yarrowia_lipolytica QVd-g--a-v----------------------------fn * X_laevis-RA51A QVd-g--a-a--------------------------m-fa * X_laevis-RA51B QVd-g--a-a--------------------------m-fa Cryptosporidium_hominis KVd-a--m-a--------------------------a-mf Cryptosporidium_parvum KVd-a--m-a--------------------------a-mf Dictyostelium_discoideum sVd-g--agg--------------------------m-fn Entamoeba_histolytica QVd-g-qa-S--------------------------m-fg Leishmania_donovani nVd-g--saq--------------------------m-fq Leishmania_tropica nVd-g--s-a---------------------q----m-fq Plasmodium_berghei KVd-a--m-S--------------------------m-fg Plasmodium_falciparum KVd-a--m-S--------------------------m-fg Tetrahymena_thermophila QVd-g--a-a--------------------------m-fa Theileria_annulata RVd-a--m-Stffgilllyiiiycyilinickfyidk-fv Theileria_parva KVd-a--m-S--------------------------t-ff Trypanosoma_brucei nVd-g--a-ap-------------------------t-fq Trypanosoma_cruzi nVd-g--s-a---------------------q----m-fq P Arabidopsis_thaliana QVd-g--s-a--------------------------l-fa P Oryza_sativa QVd-g--s-a--------------------------m-fa P Maize-R51A1 QVd-g--s-a--------------------------m-fa P Maize-R51A2 QVd-g--a-a--------------------------m-fa ============================================================================ B E_COLI KIgVmFG--Npetttggnalkfya---------------- B MYCOBACTERIUM_SMEGMATIS KIgVmFG--Spetttggkalkfya---------------- B MYCOBACTERIUM_TUBERCULOSIS KIgVmFG--Spetttggkalkfya---------------- B Acinetobacter_calcoaceticus KIgVmFG--Spetttggnalkfya---------------- B Actinobacillus_pleuropneumoniae KIgVmFG--Npetttggnalkfya---------------- B Actinobacillus_succinogenes KIgVmFG--Npetttggnalkfys---------------- B Actinomyces_bovis KIgVmFG--Spetttggkalkfya---------------- B Azotobacter_vinelandii KIgVmFG--Npetttganalkfya---------------- B Bacillus_clausii KVgVmFG--Npettpggralkfys---------------- B Bacillus_halodurans KVgVmFG--Npettpggralkfys---------------- B Bacillus_licheniformis KVgVmFG--Npettpggralkfys---------------- B Bacillus_megaterium KVgVmFG--Npettpggralkfys---------------- B Bacillus_subtilis KVgVmFG--Npettpggralkfys---------------- B Bordetella_pertussis KIgVmFG--Npetttggnalkfys---------------- B Burkholderia_fungorum KIgVmFG--Npetttggnalkfya---------------- B Chromobacterium_violaceum KIgVmFG--Npetttggnalkfya---------------- B Clostridium_acetobutylicum KVgImFG--Npettpggralkfya---------------- B Clostridium_thermocellum KVgVmFG--Npettpggralkfya---------------- B Colwellia_psychrerythraea KIgVmFG--Spetttggnalkfya---------------- B Corynebacterium_efficiens KIgVmFG--Spetttggkalkfya---------------- B Desulfotalea_psychrophila KIgVmFG--Spetttggnalkfyc---------------- B Enterococcus_faecalis KVgVmFG--Npettpggralkfya---------------- B Haemophilus_ducreyi KIgVmFG--Npetttggnalkfya---------------- B Haemophilus_influenzae KIgVmFG--Npetttggnalkfys---------------- B Histophilus_somni KIgViFG--Npetttggnalkfya---------------- B Kineococcus_radiotolerans KIgVmFG--Spetttggkalkfya---------------- B Leifsonia_xyli KVgVfFG--Spettaggkalkfya---------------- B Mannheimia_succiniciproducens KIgVmFG--Npetttggnalkfys---------------- B Nitrosomonas_europaea KIgViFG--Npetttggnalkfya---------------- B Nitrosomonas_eutropha KIgVmFG--Npetttggnalkfya---------------- B Oceanobacillus_iheyensis KVgVmFG--Npettpggralkfys---------------- B Pasteurella_multocida KIgVmFG--Npetttggnalkfya---------------- B Photobacterium_profundum KIgVmFG--Npetttggnalkfya---------------- B Photorhabdus_luminescens KIgVmFG--Npetttggnalkfya---------------- B Proteus_mirabilis KIgVmFG--Npetttggnalkfya---------------- B Pseudomonas_cepacia KIgVmFG--Npetttggnalkfys---------------- B Pseudomonas_pseudomallei KIgVmFG--Npetttggnalkfys---------------- B Shewanella_amazonensis KIgVmFG--Npetttggnalkfya---------------- B Shewanella_putrefaciens KIgVmFG--Npetttggnalkfya---------------- B Streptomyces_avermitilis KIgVmFG--Spetttggralkfya---------------- B Vibrio_alginolyticus KIgVmFG--Npetttggnalkfya---------------- B Vibrio_angustum KIgVmFG--Npetttggnalkfya---------------- B Vibrio_cholerae KIgVmFG--Npetttggnalkfya---------------- B Vibrio_fischeri KIgVmFG--Npetttggnalkfya---------------- B Vibrio_parahaemolyticus KIgVmFG--Npetttggnalkfya---------------- B Vibrio_splendidus KIgVmFG--Npetttggnalkfya---------------- B Vibrio_vulnificus KIgVmFG--Npetttggnalkfya---------------- B Yersinia_enterocolitica KIgVmFG--Npetttggnalkfya---------------- B Cupriavidus_metallidurans-Q1LR74 KIgVmFG--Spetttggnalkfya---------------- B Cupriavidus_metallidurans-RECA KIgVmFG--Spetttggnalkfya---------------- B Erwinia_carotovora-RECA KIgVmFG--Npetttggnalkfya---------------- B Erwinia_carotovora-RECA_ERWCT KIgVmFG--Npetttggnalkfya---------------- B Listeria_monocytogenes-RECA KVgVmFG--Npeitpggralkfys---------------- B Listeria_monocytogenes-RECA_LISMF KVgVmFG--Npeitpggralkfys---------------- B Neisseria_gonorrhoeae-RECA KIgVmFG--Spetttggnalkfys---------------- B Neisseria_gonorrhoeae-RECA_VAR KIgVmFG--Spetttggnalkfys---------------- B Salmonella_typhi-RECA KIgVmFG--Npetttggnalkfya---------------- B Salmonella_typhi-RECA_SALPA KIgVmFG--Npetttggnalkfya---------------- B Streptomyces_coelicolor-RECA KIgVmFG--Spetttggralkfya---------------- B Streptomyces_coelicolor-RECA_STRL KIgVmFG--Spetttggralkfya---------------- B Xylella_fastidiosa-RECA KIgVmmpgqSpetttggnalkfya---------------- B Xylella_fastidiosa-RECA_XYLFT KIgImmpgqSpetttggnalkfya---------------- B Yersinia_pestis-RECA KIgVmFG--Npetttggnalkfya---------------- B Yersinia_pestis-RECA_YERPS KIgVmFG--Npetttggnalkfya---------------- B Mycobacterium_tuberculosis-RECA KIgVmFG--Spetttggkalkfya---------------- B Mycobacterium_tuberculosis-RECA_M KIgVmFG--Spetttggkalkfya---------------- B Neisseria_meningitidis-RECA KIgVmFG--Spetttggnalkfys---------------- B Neisseria_meningitidis-RECA_NEIMA KIgVmFG--Spetttggnalkfys---------------- B Neisseria_meningitidis-RECA_VAR KIgVmFG--Spetttggnalkfys---------------- B Xanthomonas_vasicola-RECA_XANAC KIgVmmpgqSpevttggnalkfya---------------- B Xanthomonas_vasicola-RECA_XANCP KIgVmmpgqSpevttggnalkfya---------------- B Xanthomonas_vasicola-YP_201580 KIgVmmpgqSpevttggnalkfya---------------- B Pseudomonas_aeruginosa-Q48F94 KIgVmFG--Spetttggnalkfya---------------- B Pseudomonas_aeruginosa-RECA KIgVmFG--Npetttggnalkfya---------------- B Pseudomonas_aeruginosa-RECA_PSEF5 KIgVmFG--Spetttggnalkfya---------------- B Pseudomonas_aeruginosa-RECA_PSEFL KIgVmFG--Spetttggnalkfya---------------- B Pseudomonas_aeruginosa-RECA_PSEPK KIgVmFG--Spetttggnalkfya---------------- B Pseudomonas_aeruginosa-RECA_PSEPU KIgVmFG--Spetttggnalkfya---------------- B Pseudomonas_aeruginosa-RECA_PSESM KIgVmFG--Spetttggnalkfya---------------- ============================================================================ B DEINOCOCCUS_RADIODURANS KIgVmYGnpetttggralkfya------------------ B Deinococcus_geothermalis KIgVmYGnpetttggralkfya------------------ B Thermus_aquaticus-RECA KVgVmYGnpettpggralkfys------------------ B Thermus_aquaticus-RECA_THET2 KVgVtYGnpettpggralkfya------------------ B Thermus_aquaticus-RECA_THET8 KVgVtYGnpettpggralkfya------------------ B Thermus_aquaticus-RECA_THETH KVgVtYGnpettpggralkfya------------------ ============================================================================ Consensus kixvxfgxxsxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 530 540 550 560 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxSlRLnLKKxqxxxxxxxxxxxdqr ============================================================================ A PYROCOCCUS_FURIOSUS ----------------TLRVyLRKgKg----------gKR A Archaeoglobus_fulgidus ----------------TfRIyLKKgKd----------DlR A Pyrococcus_abyssi ----------------TLRVyLRKgKg----------gKR ============================================================================ A METHANOCOCCUS_VOLTAE ----------------TfRffVRKgKg----------DKR A Methanococcus_jannaschii ----------------TfRIfLRKaKg----------DKR A Methanococcus_maripaludis ----------------TfRffLRKsKg----------DKR ============================================================================ A SULFOLOBUS_SOLFATARICUS ----------------gIRIqLKKsRg----------NRR A Desulfurococcus_amylolyticus ----------------gVRIqLRKsKg----------NKR A Sulfolobus_acidocaldarius ----------------gIRVqLKKsRg----------NKR A Sulfolobus_tokodaii ----------------gIRVqLKKsRg----------NKR A Aeropyrum_pernix-RADA ----------------gVRVyLKKsRg----------NKR A Aeropyrum_pernix-RADA_VAR_OH1 ----------------gVRVyLKKsRg----------NKR A Aeropyrum_pernix-RADA_VAR_OH2 ----------------gVRVyLKKsRg----------NKR A Aeropyrum_pernix-RADA_VAR_OH3 ----------------gVRVyLKKsRg----------DKR A Aeropyrum_pernix-RADA_VAR_TB1 ----------------gVRVyLKKgRg----------NKR A Aeropyrum_pernix-RADA_VAR_TB2 ----------------gVRVyLKKsRg----------sKR A Aeropyrum_pernix-RADA_VAR_TB6 ----------------gVRVyLKKsRg----------NKR ============================================================================ * HUMAN adpkkpiggniiahasTtRLyLRKgRg----------EtR * S_CEREVISIAE pdpkkptggnimahssTtRLgfKKgKg----------cQR * Apis_mellifera gdqkkpigghiiahasTtRLyLRKgRg----------EtR * Aspergillus_flavus pdpkkpiggniiahasTtRLSLKKgRg----------EtR * Aspergillus_fumigatus pdpkkpiggniiahasTtRLSLKKgRg----------EtR * Bovine adpkkpiggniiahasTtRLyLRKgRg----------EtR * C_elegans adakkpigghiiahmsTtRLyLRKgKg----------EnR * Candida_albicans pdpkkpiggniiahssTtRLSfKKgRg----------EtR * Candida_glabrata pdpkkpiggnimahssTtRLgfKKgKg----------cQR * Canis_lupus adpkkpiggniiahasTtRLyLRKgRg----------EtR * Chaetomium_globosum pdpkkpiggnimahssTtRISLKKgRg----------EtR * Coccidioides_immitis pdpkkpiggniiahasTtRLSLKKgRg----------EtR * Coprinus_cinereus gnekkpiggnimahasTtRLqLKKgRg----------NtR * Cricetulus_griseus adpkkpiggniiahasTtRLyLRKgRg----------EtR * Cryptococcus_neoformans adakkpiggnimahasTtRLNLRKgRg----------tsR * Danio_rerio adpkkpiggnilahasTtRLyLRKgRg----------EtR * Debaryomyces_hansenii pdpkkpiggniiahssTtRLSfKKgRa----------EQR * D_melanogaster -dakkpigghimahssTtRLyLRKgKg----------EtR * D_pseudoobscura adakkpvgghilahasTtRLyLRKgKg----------EtR * Emericella_nidulans pdpkkpiggniiahasTtRLSLKKgRg----------EtR * Encephalitozoon_cuniculi gdikkpiggnimahasTtRLyLRKgRg----------EtR * Eremothecium_gossypii pdpkkpiggnimahssTtRLgfKKgKg----------cQR * Chicken adpkkpiggniiahasTtRLyLRKgRg----------EtR * Gibberella_zeae pdpkkpiggniiahasTtRISLKKgRa----------EtR * Kluyveromyces_lactis pdpkkpfggnimahssTtRLgfKKgKg----------pQR * Mouse adpkkpiggniiahasTtRLyLRKgRg----------EtR * Neurospora_crassa pdpkkpiggniiahasTtRISLKKgRg----------EtR * Rabbit adpkkpiggniiahasTtRLyLRKgRg----------EtR * Pichia_angusta pdpkkpiggnivahssTtRLyfKKaKg----------anR * Rat adpkkpiggniiahasTtRLyLRKgRg----------EtR * Schizosaccharomyces_pombe pdpkkpiggnilahssTtRLSLRKgRg----------EQR * Strongylocentrotus_purpuratus sdpkkpigghimahasTtRLyLRKgRg----------EtR * Tetraodon_nigroviridis gygiteetsefvqlvlfavctLRKgRg----------EtR * Tribolium_castaneum adpkkpiggnimahssTtRLSLRKgRg----------EaR * Ustilago_maydis adakkpiggnivahasTtRLSLRKgRg----------NQR * X_tropicalis adpkkpiggniiahasTtRLyLRKgRg----------EtR * Yarrowia_lipolytica pdpkkpiggnivahasTtRLyfKKgRg----------vQR * X_laevis-RA51A adpkkpiggniiahasTtRLyLRKgRg----------EtR * X_laevis-RA51B adpkkpiggniiahasTtRLyLRKgRg----------EtR Cryptosporidium_hominis qndkvpiggniiahasqtRLfLKKgRg----------EtR Cryptosporidium_parvum qndkvpiggniiahasqtRLfLKKgRg----------EtR Dictyostelium_discoideum pdpkkpigghimahssTtRLSLRKgKg----------EmR Entamoeba_histolytica gdtkkpvggniiahasTtRLyLRKgKg----------EaR Leishmania_donovani adskkpigghimahasTtRLSLRKgRg----------EQR Leishmania_tropica adskkpigghimahasTtRLSLRKgRg----------EQR Plasmodium_berghei ghekipiggniiahasqtRLyLRKgRg----------EsR Plasmodium_falciparum ghekipiggniiahasqtRLyLRKgRg----------EsR Tetrahymena_thermophila gdmkkpiggnimahasTtRLyLRKgRg----------EsR Theileria_annulata gndklpvgghiiahasqtRLfLRQsKg----------EsR Theileria_parva gndklpvgghiiahasqtRLfLRQsKg----------EsR Trypanosoma_brucei adskkpigghimahasTtRLSLRKgRg----------EQR Trypanosoma_cruzi adakkpigghimahasTtRLSLRKgRg----------EQR P Arabidopsis_thaliana gpqfkpiggnimahatTtRLaLRKgRa----------EER P Oryza_sativa gpqikpiggnimahasTtRLaLRKgRg----------EER P Maize-R51A1 gpqfkpiggnimahasTtRLaLRKgRg----------EER P Maize-R51A2 gpqikpiggnimahasTtRLfLRKgRg----------EER ============================================================================ B E_COLI ----------------SVRLDIRRigavkegenvvg-sEt B MYCOBACTERIUM_SMEGMATIS ----------------SVRLDVRRiEtlkdgtdavg-NRt B MYCOBACTERIUM_TUBERCULOSIS ----------------SVRMDVRRiEtlkdgtnavg-NRt B Acinetobacter_calcoaceticus ----------------SVRLDIRRigqvkegdeiig-sEt B Actinobacillus_pleuropneumoniae ----------------SVRLDIRRsgvvkdgdevvg-sEt B Actinobacillus_succinogenes ----------------SVRLDIRRigsvkagdeiig-NEt B Actinomyces_bovis ----------------SVRLDVRRiEtlkdgsdavg-NRt B Azotobacter_vinelandii ----------------SVRLDIRRtgavkesdevig-sEt B Bacillus_clausii ----------------SVRLeVRRaEalkqgneivg-NRt B Bacillus_halodurans ----------------SVRLeVRRaEtlkqgndmvg-NKt B Bacillus_licheniformis ----------------SVRLeVRRaEqlkqgndvmg-NKt B Bacillus_megaterium ----------------SVRLeVRRaEqlkqgndivg-NKt B Bacillus_subtilis ----------------SVRLeVRRaEqlkqgndvmg-NKt B Bordetella_pertussis ----------------SVRLDIRRigaikkgdevvg-NEt B Burkholderia_fungorum ----------------SVRLDIRRigsikkndevig-NEt B Chromobacterium_violaceum ----------------SVRLDIRRtggikkgdevig-Ndt B Clostridium_acetobutylicum ----------------SVRMDIRKidtikqgeemig-NRv B Clostridium_thermocellum ----------------SVRLDVRRlEsikqgnevig-sRt B Colwellia_psychrerythraea ----------------SVRLDIRRigavkngdeivg-NEt B Corynebacterium_efficiens ----------------SVRIDVRRiQtlkdgqdaig-NRt B Desulfotalea_psychrophila ----------------SeRLDIRRigaikdgqeitg-NRt B Enterococcus_faecalis ----------------TVRLeVRRaEqlkqgtdivg-NRt B Haemophilus_ducreyi ----------------SVRLDIRRsgvvkdgdevvg-sEt B Haemophilus_influenzae ----------------SVRLDIRRtgsvkdgeniig-NEt B Histophilus_somni ----------------SVRLDIRRvgsikngdevig-NEt B Kineococcus_radiotolerans ----------------SVRLDVRRiEtlkdgtnpvg-NRt B Leifsonia_xyli ----------------SVRLDIRRiEtlkdgtdavg-NRt B Mannheimia_succiniciproducens ----------------SVRLDIRRvgavkdgdeiig-NEt B Nitrosomonas_europaea ----------------SVRLDIRRtgsikrgeemvg-NEt B Nitrosomonas_eutropha ----------------SVRLDIRRtgsikrgeeivg-NEt B Oceanobacillus_iheyensis ----------------SVRLeVRRaEtlklgndavg-NKa B Pasteurella_multocida ----------------SVRLDIRRtgaikegeevig-NEt B Photobacterium_profundum ----------------SVRLDIRRtgaikdgdevvg-NEt B Photorhabdus_luminescens ----------------SVRLDIRRigsvkngeevvg-sEt B Proteus_mirabilis ----------------SVRLDIRRigsvkngdevig-sEt B Pseudomonas_cepacia ----------------SVRLDIRRigsikkndevig-NEt B Pseudomonas_pseudomallei ----------------SVRLDIRRigsikkndevig-NEt B Shewanella_amazonensis ----------------SVRLDIRRtgaikegdevvg-NEt B Shewanella_putrefaciens ----------------SVRLDIRRtgaikegdevvg-NEt B Streptomyces_avermitilis ----------------SVRLDIRRiEtlkdgtdavg-NRt B Vibrio_alginolyticus ----------------SVRLDIRRtgaikegdevvg-NEt B Vibrio_angustum ----------------SVRLDIRRtgaikegdevvg-NEt B Vibrio_cholerae ----------------SVRLDIRRtgaikegeevvg-NEt B Vibrio_fischeri ----------------SVRLDIRRtgavkdgdevvg-NEt B Vibrio_parahaemolyticus ----------------SVRLDIRRtgaikegdevvg-NEt B Vibrio_splendidus ----------------SVRLDIRRtgaikdgdevvg-NEt B Vibrio_vulnificus ----------------SVRLDIRRtgaikegdevvg-NEt B Yersinia_enterocolitica ----------------SVRLDIRRigavkdgdvvvg-sEt B Cupriavidus_metallidurans-Q1LR74 ----------------SVRLDIRRigsikkgdevvg-NEt B Cupriavidus_metallidurans-RECA ----------------SVRLDIRRigsikkgdevvg-NEt B Erwinia_carotovora-RECA ----------------SVRLDIRRigsvkngdevvg-sEt B Erwinia_carotovora-RECA_ERWCT ----------------SVRLDIRRtgaikegeevvg-sEt B Listeria_monocytogenes-RECA ----------------TVRLeVRRaEqlkqgtdvmg-NKt B Listeria_monocytogenes-RECA_LISMF ----------------TVRLeVRRaEqlkqgtdvmg-NKt B Neisseria_gonorrhoeae-RECA ----------------SVRLDIRRtgsikkgeevlg-NEt B Neisseria_gonorrhoeae-RECA_VAR ----------------SVRLDIRRtgsikkgeevlg-NEt B Salmonella_typhi-RECA ----------------SVRLDIRRigavkegdnvvg-sEt B Salmonella_typhi-RECA_SALPA ----------------SVRLDIRRigavkegdnvvg-sEt B Streptomyces_coelicolor-RECA ----------------SVRLDIRRiEtlkdgtdavg-NRt B Streptomyces_coelicolor-RECA_STRL ----------------SVRLDIRRiEtlkdgtdavg-NRt B Xylella_fastidiosa-RECA ----------------SVRLDIRRigaikkgdeiig-NQt B Xylella_fastidiosa-RECA_XYLFT ----------------SVRLDIRRigaikkgdeiig-NQt B Yersinia_pestis-RECA ----------------SVRLDIRRigavkdgdvvvg-sEt B Yersinia_pestis-RECA_YERPS ----------------SVRLDIRRigavkdgdvvvg-sEt B Mycobacterium_tuberculosis-RECA ----------------SVRMDVRRvEtlkdgtnavg-NRt B Mycobacterium_tuberculosis-RECA_M ----------------SVRMDVRRiEtlkdgtnavg-NRt B Neisseria_meningitidis-RECA ----------------SVRLDIRRtgsikkgeevlg-NEt B Neisseria_meningitidis-RECA_NEIMA ----------------SVRLDIRRtgsikkgeevlg-NEt B Neisseria_meningitidis-RECA_VAR ----------------SVRLDIRRtgsikkgeevlg-NEt B Xanthomonas_vasicola-RECA_XANAC ----------------SVRLDIRRigaikkgdeiig-NQt B Xanthomonas_vasicola-RECA_XANCP ----------------SVRLDIRRigaikkgdeiig-NQt B Xanthomonas_vasicola-YP_201580 ----------------SVRLDIRRigaikkgdeiig-NQt B Pseudomonas_aeruginosa-Q48F94 ----------------SVRLDIRRtgavkegdevvg-sEt B Pseudomonas_aeruginosa-RECA ----------------SVRLDIRRtgavkegdevvg-sEt B Pseudomonas_aeruginosa-RECA_PSEF5 ----------------SVRLDIRRtgavkegdevvg-sEt B Pseudomonas_aeruginosa-RECA_PSEFL ----------------SVRLDIRRtgavkegdevvg-sEt B Pseudomonas_aeruginosa-RECA_PSEPK ----------------SVRLDIRRtgavkegdevvg-sEt B Pseudomonas_aeruginosa-RECA_PSEPU ----------------SVRLDIRRtgavkegdevvg-sEt B Pseudomonas_aeruginosa-RECA_PSESM ----------------SVRLDIRRtgavkegdevvg-sEt ============================================================================ B DEINOCOCCUS_RADIODURANS ----------------SVRLDVRKigqptkvgndavaNtv B Deinococcus_geothermalis ----------------SVRLDVRKigqpvklgndavgNtv B Thermus_aquaticus-RECA ----------------SVRLDVRKsgqpikvgneavgiKv B Thermus_aquaticus-RECA_THET2 ----------------SVRLDVRKsgqpikvgneavgvKv B Thermus_aquaticus-RECA_THET8 ----------------SVRLDVRKsgqpikvgneavgvKv B Thermus_aquaticus-RECA_THETH ----------------SVRLDVRKsgqpikvgneavgvKv ============================================================================ Consensus xxxxxxxxxxxxxxxxSlRLnLKKxqxxxxxxxxxxxdqr 570 580 590 600 ----:----|----:----|----:----|----:----| Consensus xvRVvxspvlpxexEaxfxIxxxeGInnxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS iaRLIdaPhLP-EgEAvFsIt-eKGIeD------------ A Archaeoglobus_fulgidus iaRLIdSPhLP-EgEAiFrVt-erGIeDa-eekdkkkrk- A Pyrococcus_abyssi vaRLIdaPhLP-EgEAvFrIt-eKGIeD------------ ============================================================================ A METHANOCOCCUS_VOLTAE vaKLydSPhLP-DaEAiFrIt-eKGIqD------------ A Methanococcus_jannaschii vaKLydSPhLP-DaEAmFrIt-eKGIHD------------ A Methanococcus_maripaludis vaKLydSPhLP-DsEAvFrIt-eKGIqD------------ ============================================================================ A SULFOLOBUS_SOLFATARICUS iaRVVdaPhLP-EgEvvFaLt-eEGIrD--ae-------- A Desulfurococcus_amylolyticus iaRVVdaPhLP-EgEvvFvIt-eEGIrD--se-------- A Sulfolobus_acidocaldarius iaRIVdaPhLP-EgEvvFaIt-eEGVrD--ae-------- A Sulfolobus_tokodaii iaRIVdaPhLP-EgEvvFaIt-eEGVrD--ae-------- A Aeropyrum_pernix-RADA iaRVVdaPhLP-EgEtvFaIt-ewGIrD--pe-------- A Aeropyrum_pernix-RADA_VAR_OH1 iaRVVdaPhLP-EgEtvFaIt-ewGIrD--pe-------- A Aeropyrum_pernix-RADA_VAR_OH2 iaRVVdaPhLP-EgEtvFaIt-ewGIrD--pe-------- A Aeropyrum_pernix-RADA_VAR_OH3 iaRVVdaPhLP-EgEtvFaIt-ewGIrD--pe-------- A Aeropyrum_pernix-RADA_VAR_TB1 iaRVVdaPhLP-EgEtvFaIt-ewGIrD--pe-------- A Aeropyrum_pernix-RADA_VAR_TB2 iaRVVdaPhLP-EgEtvFaIt-ewGIrD--pe-------- A Aeropyrum_pernix-RADA_VAR_TB6 iaRVVdaPhLP-EgEAvFaIt-ewGIrD--pe-------- ============================================================================ * HUMAN icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * S_CEREVISIAE lcKVVdSPcLP-EaEcvFaIy-eDGVgD---p-r------ * Apis_mellifera icKIydSPcLP-EsEAmFaIn-aDGIgD---v-k------ * Aspergillus_flavus vcKIydSPcLP-EsDclFaIn-eDGIgDp-sp-k------ * Aspergillus_fumigatus vcKIydSPcLP-EsDclFaIn-eDGIgDp-sp-k------ * Bovine icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * C_elegans vaKMVqSPnLP-EaEAtYsIt-nhGIeD---a-r------ * Candida_albicans icKIydSPcLP-EsEciFaIy-eDGIgD---p-k------ * Candida_glabrata ycKVVdSPcLP-EaEcvFaIy-eDGIgD---p-r------ * Canis_lupus icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Chaetomium_globosum iaKIydSPcLP-EgDAlFaIn-eDGIgDp--spk------ * Coccidioides_immitis icKIydSPcLP-EsDclFaIn-eDGIgDp-sp-k------ * Coprinus_cinereus acKIydSPcLP-EsEttFaIl-pgGIgD---p-e------ * Cricetulus_griseus icKVydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Cryptococcus_neoformans vcKIVdSPcLP-EaEAiFaIn-pnGIgD---p-e------ * Danio_rerio icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Debaryomyces_hansenii icKIydSPcLP-EsEcvFaIy-eDGIgD---p-k------ * D_melanogaster icKIydSPcLP-EsEAmFaIl-pDGIgD---a-r------ * D_pseudoobscura icKIydSPcLP-EsEAmFaIl-pDGIgD---a-k------ * Emericella_nidulans vcKIydSPcLP-EsDclFaIn-eDGIgDp-sp-k------ * Encephalitozoon_cuniculi icKIydSPcLP-EsEAvFaIt-eQGIND---p-d------ * Eremothecium_gossypii lcKVVdSPcLP-EaEcvFaIy-eDGIgD---p-r------ * Chicken icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Gibberella_zeae iaKIydSPcLP-EsDtlFaIg-eEGIgDp-ap-k------ * Kluyveromyces_lactis ycKVVdSPcLP-EaEcvFaIy-eDGIgD---p-r------ * Mouse icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Neurospora_crassa iaKIydSPcLP-EsDclFaIn-eDGIgDp-sp-k------ * Rabbit icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Pichia_angusta icKIydSPcLa-EsEtvFaLg-qgGViD---p-s------ * Rat icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Schizosaccharomyces_pombe icKIydSPcLP-EsEAiFaIn-sDGVgD---p-k------ * Strongylocentrotus_purpuratus icKIydSPcLP-EaEAmFaIn-pDGVgD---a-k------ * Tetraodon_nigroviridis icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Tribolium_castaneum vcKIydSPcLP-EsEAiFaIr-pDGIgD---v-q------ * Ustilago_maydis icRIadSPcLP-EaDAvFaIg-pEGIiD---p-v------ * X_tropicalis icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * Yarrowia_lipolytica icKIydSPcLP-EsgcvFaIh-eDGIgD---p-k------ * X_laevis-RA51A icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ * X_laevis-RA51B icKIydSPcLP-EaEAmFaIn-aDGVgD---a-k------ Cryptosporidium_hominis icKIydSPnLP-EgDAtFsIt-egGIND---p-k------ Cryptosporidium_parvum icKIydSPnLP-EgDAtFsIt-egGIND---p-k------ Dictyostelium_discoideum icKIydSPsLP-EsEkpFgIy-sDGISD---y-k------ Entamoeba_histolytica icKVydSPcLP-EsEAsFaIt-tnGIeD---v-k------ Leishmania_donovani iIKVydSPcLa-EaEAiFgIy-dDGVgD---a-r------ Leishmania_tropica iIKVydSPcLa-EaEAiFgIy-dDGVgD---a-r------ Plasmodium_berghei icKIydSPVLP-EgEAvFaIt-egGIaD---y-e------ Plasmodium_falciparum icKIydSPVLP-EgEAvFaIt-egGIaD---y-e------ Tetrahymena_thermophila icKIydSPcLP-EsEAiYaIg-kgGIeD---f-n------ Theileria_annulata icKVydSPVLP-EgEAvFaIt-dgGIND---y-h------ Theileria_parva icKIydSPVLP-EgEAvFaIt-dgGIND---y-h------ Trypanosoma_brucei iIKVydSPcLa-EsEAiFgIy-enGVgD---v-r------ Trypanosoma_cruzi iMKVydSPcLa-EaEAiFgIy-eDGVgD---a-r------ P Arabidopsis_thaliana icKVIsSPcLP-EaEArFqIs-tEGVtD---c-k------ P Oryza_sativa icKVIsSPcLa-EaEArFqIa-sEGVaD---v-k------ P Maize-R51A1 icKVIsSPcLa-EaEArFqLa-sEGIaD---v-k------ P Maize-R51A2 icKVIsSPcLa-EaEArFqIs-sEGVtD---v-k------ ============================================================================ B E_COLI rVKVVkNkIaapfkQAeFqIlygEGINf-yge-------l B MYCOBACTERIUM_SMEGMATIS rVKVVkNkVsPpfkQAeFdIlygQGISr-egs-------l B MYCOBACTERIUM_TUBERCULOSIS rVKIVkNkxsPpfkQAeFdIlygrGISr-egs-------l B Acinetobacter_calcoaceticus kVKVVkNkMaPpfrEAiFqIlygKGVNq-lge-------l B Actinobacillus_pleuropneumoniae kVKIVkNkVaPpfrEvqFdImygEGISr-mne-------l B Actinobacillus_succinogenes rVKVVkNkLaapfrtvdFqImygEGISk-nge-------l B Actinomyces_bovis rVKVVkNkVsPpfkQAeFdIlygQGISk-egs-------l B Azotobacter_vinelandii rVKVVkNkVaPpfrQAeFqIlygKGIyr-nge-------i B Bacillus_clausii kIKVVkNkVaPpfrlAevdImygEGISr-egs-------m B Bacillus_halodurans kIKVVkNkVaPpfkQAevdImygEGISr-egs-------i B Bacillus_licheniformis kIKVVkNkVaPpfrtAevdImygEGISk-ege-------i B Bacillus_megaterium rIKVVkNkVaPpfraAevdImygEGISk-ege-------i B Bacillus_subtilis kIKVVkNkVaPpfrtAevdImygEGISk-ege-------i B Bordetella_pertussis rVKVVkNkVaPpfkQAeFdImygsGISr-ege-------i B Burkholderia_fungorum rVKVVkNkVsPpfrEAiFdIlygEGISr-qge-------i B Chromobacterium_violaceum rVKVVkNkVsPpfrQAdFeIlygEGISr-qge-------i B Clostridium_acetobutylicum rVKVVkNkVaPpfkQAeFdImynEGISr-egn-------i B Clostridium_thermocellum kVKVVkNkVaPpfkEAeFdIiygQGISk-egn-------i B Colwellia_psychrerythraea rVKVVkNkIaPpfkQAeFqIlygEGINN-lge-------l B Corynebacterium_efficiens raKIVkNkVsPpfkiAeFdIiygEGISr-ess-------i B Desulfotalea_psychrophila rVKVVkNkVaPpfkiAeFdIiygEGISk-igd-------m B Enterococcus_faecalis kIKVVkNkVaPpfkvAevdImygQGISq-ege-------l B Haemophilus_ducreyi kVKIVkNkVaPpfrEvqFdImygEGIar-mne-------l B Haemophilus_influenzae rVKVVkNkLaapfrQvdFqIlygEGISk-age-------l B Histophilus_somni rVKVVkNkVaPpfrQvdFqIlygEGISr-nge-------l B Kineococcus_radiotolerans rVKVVkNkVsPpfkQAeFdIiygQGISr-egg-------l B Leifsonia_xyli rVKVVkNkMaPpfkQAeFdIlygvGISH-egs-------l B Mannheimia_succiniciproducens rVKVVkNkLaPpfrQvdFqIlygEGISk-nge-------l B Nitrosomonas_europaea rVKIVkNkVaPpfkQAdFdIlygEGISr-ese-------i B Nitrosomonas_eutropha rVKVVkNkVaPpfkQAdFaIlygEGISr-ese-------i B Oceanobacillus_iheyensis rIKVVkNkVaPpfkQAevdImygKGISk-ege-------v B Pasteurella_multocida rVKVVkNkVaapfrQvdFqIlygQGISk-tge-------l B Photobacterium_profundum rIKVVkNkIaapfkQAetqIlygQGfNr-nge-------l B Photorhabdus_luminescens rVKVVkNkVaapfkQAeFqImygEGINt-yge-------l B Proteus_mirabilis rVKVVkNkVaapfkQAeFqImygEGINt-yge-------l B Pseudomonas_cepacia rVKVVkNkVsPpfrEAiFdIlygEGISr-qge-------i B Pseudomonas_pseudomallei rVKVVkNkVsPpfrEAiFdIlygEGISr-qge-------i B Shewanella_amazonensis rVKVVkNkIaapfrQAdFqIlygQGINr-tge-------l B Shewanella_putrefaciens rVKVVkNkVaapfkQAeFqIlygQGINr-tge-------l B Streptomyces_avermitilis rVKVVkNkVaPpfkQAeFdIlygQGISr-egg-------l B Vibrio_alginolyticus rIKVVkNkIaapfkEAntqImygQGfNr-ege-------l B Vibrio_angustum rIKVVkNkIaapfkQAetqIlygQGfNr-nge-------l B Vibrio_cholerae rIKVVkNkIaapfkEAntqImygQGfNr-ege-------l B Vibrio_fischeri rIKVVkNkIaapfkQAetqImygQGfNr-ege-------l B Vibrio_parahaemolyticus rIKVVkNkIaapfkEAntqImygQGfNr-ege-------l B Vibrio_splendidus rIKVVkNkIaapfkQAetqIlygKGfNr-ege-------l B Vibrio_vulnificus rIKVVkNkIaapfkEAntqImygQGfNr-ege-------l B Yersinia_enterocolitica rVKVVkNkIaapfkQAeFqIlygEGINi-nge-------l B Cupriavidus_metallidurans-Q1LR74 kVKVVkNkVsPpfrEAfFdIlygQGISr-qge-------i B Cupriavidus_metallidurans-RECA kVKVVkNkVsPpfrEAfFdIlygQGISr-qge-------i B Erwinia_carotovora-RECA rVKVVkNkIaapfkQAeFqImygEGINt-fge-------l B Erwinia_carotovora-RECA_ERWCT rVKVVkNkVaapfkQAeFqIlygEGINi-hge-------l B Listeria_monocytogenes-RECA kIKVVkNkVaPpfriAevdImygEGISr-ege-------l B Listeria_monocytogenes-RECA_LISMF kIKVVkNkVaPpfriAevdImygEGISr-ege-------l B Neisseria_gonorrhoeae-RECA rVKVIkNkVaPpfrQAeFdIlygEGISw-ege-------l B Neisseria_gonorrhoeae-RECA_VAR rVKVIkNkVaPpfrQAeFdIlygEGISw-ege-------l B Salmonella_typhi-RECA rVKVVkNkIaapfkQAeFqIlygEGINf-yge-------l B Salmonella_typhi-RECA_SALPA rVKVVkNkIaapfkQAeFqIlygEGINf-yge-------l B Streptomyces_coelicolor-RECA rVKVVkNkVaPpfkQAeFdIlygQGISr-egg-------l B Streptomyces_coelicolor-RECA_STRL rVKVVkNkVaPpfkQAeFdIlygQGISr-egg-------l B Xylella_fastidiosa-RECA kIKVVkNkLaPpfkQvvteIlygEGISr-ege-------l B Xylella_fastidiosa-RECA_XYLFT kIKVVkNkLaPpfkQvvteIlygEGISr-ege-------l B Yersinia_pestis-RECA rVKVVkNkIaapfkQAeFqIlygEGINi-nge-------l B Yersinia_pestis-RECA_YERPS rVKVVkNkIaapfkQAeFqIlygEGINi-nge-------l B Mycobacterium_tuberculosis-RECA rVKVVkNkcsPpfkQAeFdIlygKGISr-egs-------l B Mycobacterium_tuberculosis-RECA_M rVKIVkNkVsPpfkQAeFdIlygrGISr-egs-------l B Neisseria_meningitidis-RECA rVKVIkNkVaPpfrQAeFdIlygEGISw-ege-------l B Neisseria_meningitidis-RECA_NEIMA rVKVIkNkVaPpfrQAeFdIlygEGISw-ege-------l B Neisseria_meningitidis-RECA_VAR rVKVIkNkVaPpfrQAeFdIlygEGISw-ege-------l B Xanthomonas_vasicola-RECA_XANAC kIKVVkNkLaPpfkQvvteIlygEGISr-ege-------l B Xanthomonas_vasicola-RECA_XANCP kIKVVkNkLaPpfkQviteIlygEGISr-ege-------l B Xanthomonas_vasicola-YP_201580 kIKVVkNkLaPpfkQvvteIlygEGISr-ege-------l B Pseudomonas_aeruginosa-Q48F94 rVKVVkNkVaPpfrQAeFqIlygKGIyl-nge-------i B Pseudomonas_aeruginosa-RECA rVKVVkNkVsPpfrQAeFqIlygKGIyr-tge-------i B Pseudomonas_aeruginosa-RECA_PSEF5 rVKIVkNkVaPpfrQAeFqIlygKGIyl-nge-------i B Pseudomonas_aeruginosa-RECA_PSEFL rVKVVkNkVaPpfrQAeFqIlygKGIyl-nge-------m B Pseudomonas_aeruginosa-RECA_PSEPK rVKIVkNkVsPpfrQAeFqIlygKGIyr-nge-------i B Pseudomonas_aeruginosa-RECA_PSEPU rVKIVkNkVsPpfrQAeFqIlygKGIyr-nge-------i B Pseudomonas_aeruginosa-RECA_PSESM rVKVVkNkVaPpfrQAeFqIlygKGIyl-nge-------i ============================================================================ B DEINOCOCCUS_RADIODURANS kIKtVkNkVaapfkEvelaLvygKGfDq-lsd-------l B Deinococcus_geothermalis kVKtVkNkVaPpfkEveltLlygKGfDq-lsd-------l B Thermus_aquaticus-RECA kVKVVkNkLaPpfrEAeleIyfgrGLDp-vmd-------l B Thermus_aquaticus-RECA_THET2 rVKVVkNkLaPpfrEAeleIyfgrGLDp-vad-------l B Thermus_aquaticus-RECA_THET8 rVKVVkNkLaPpfrEAeleIyfgrGLDp-vad-------l B Thermus_aquaticus-RECA_THETH rVKVVkNkLaPpfrEAeleIyfgrGLDp-vad-------l ============================================================================ Consensus xvRVvxspvlpxexEaxfxIxxxeGInnxxxxxxxxxxxx 610 620 630 640 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxexnxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS ---------------------------------------- A Archaeoglobus_fulgidus ----k----------------------------------- A Pyrococcus_abyssi ---------------------------------------- ============================================================================ A METHANOCOCCUS_VOLTAE ---------------------------------------- A Methanococcus_jannaschii ---------------------------------------- A Methanococcus_maripaludis ---------------------------------------- ============================================================================ A SULFOLOBUS_SOLFATARICUS ---------------------------E------------ A Desulfurococcus_amylolyticus ---------------------------Ee----------- A Sulfolobus_acidocaldarius ---------------------------E------------ A Sulfolobus_tokodaii ---------------------------E------------ A Aeropyrum_pernix-RADA ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH3 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB6 ---------------------------------------- ============================================================================ * HUMAN ---------------------------D------------ * S_CEREVISIAE ---------------------------EeD-e-------- * Apis_mellifera ---------------------------E------------ * Aspergillus_flavus ---------------------------D----lenn---- * Aspergillus_fumigatus ---------------------------D----lend---- * Bovine ---------------------------D------------ * C_elegans ---------------------------E-D---------- * Candida_albicans ---------------------------veDne-------- * Candida_glabrata ---------------------------EeD-e-------- * Canis_lupus ---------------------------D------------ * Chaetomium_globosum ---------------------------D-lek--e----- * Coccidioides_immitis ---------------------------D---lekde---- * Coprinus_cinereus ---------------------------EeS---------- * Cricetulus_griseus ---------------------------D------------ * Cryptococcus_neoformans ---------------------------Elq-e-------- * Danio_rerio ---------------------------D------------ * Debaryomyces_hansenii ---------------------------teDd---dn---- * D_melanogaster ---------------------------Es----------- * D_pseudoobscura ---------------------------EgH---------- * Emericella_nidulans ---------------------------D----lend---- * Encephalitozoon_cuniculi ---------------------------E------------ * Eremothecium_gossypii ---------------------------EdDe---d----- * Chicken ---------------------------E------------ * Gibberella_zeae ---------------------------D-tekd------- * Kluyveromyces_lactis ---------------------------EdD-d-------- * Mouse ---------------------------D------------ * Neurospora_crassa ---------------------------D-mekmnq----- * Rabbit ---------------------------D------------ * Pichia_angusta ---------------------------Deteaaede---- * Rat ---------------------------D------------ * Schizosaccharomyces_pombe ---------------------------Eiiapv------- * Strongylocentrotus_purpuratus ---------------------------D------------ * Tetraodon_nigroviridis ---------------------------D------------ * Tribolium_castaneum ---------------------------E------------ * Ustilago_maydis ---------------------------D------------ * X_tropicalis ---------------------------D------------ * Yarrowia_lipolytica ---------------------------Dee---------- * X_laevis-RA51A ---------------------------D------------ * X_laevis-RA51B ---------------------------D------------ Cryptosporidium_hominis ---------------------------Dek---------- Cryptosporidium_parvum ---------------------------Dek---------- Dictyostelium_discoideum ---------------------------Eq----------- Entamoeba_histolytica ---------------------------D-D---------- Leishmania_donovani ---------------------------D------------ Leishmania_tropica ---------------------------D------------ Plasmodium_berghei ---------------------------Ek----------- Plasmodium_falciparum ---------------------------Ek----------- Tetrahymena_thermophila ---------------------------E------------ Theileria_annulata ---------------------------Dr----------- Theileria_parva ---------------------------Dr----------- Trypanosoma_brucei ---------------------------D------------ Trypanosoma_cruzi ---------------------------D------------ P Arabidopsis_thaliana ---------------------------D------------ P Oryza_sativa ---------------------------D------------ P Maize-R51A1 ---------------------------D------------ P Maize-R51A2 ---------------------------D------------ ============================================================================ B E_COLI vdlgvkekliekagawysykgekigqgKaNa-----tawl B MYCOBACTERIUM_SMEGMATIS idmgvehgfirksgswftyegeqlgqgKeNa-----rkfl B MYCOBACTERIUM_TUBERCULOSIS idmgvdqgfirksgswftyegeqlgqgKeNa-----rtfl B Acinetobacter_calcoaceticus vdlavqqnivqkagawysyqgnkigqgKnNv-----iryl B Actinobacillus_pleuropneumoniae lilaeangfiqkagawfsyegtkigqgKnNa-----ikwl B Actinobacillus_succinogenes ielgvkqklvqksgawfayegqkigqgKaNa-----mkwl B Actinomyces_bovis idmgveqgfirksgswytyegdqlgqgKeNa-----rkfl B Azotobacter_vinelandii idlgvqlglleksgawysyqgskigqgKaNa-----akfl B Bacillus_clausii ldiaseldiveksgawysykgdrlgqgreNs-----kqfl B Bacillus_halodurans ldiaseldivqksgawysfnderlgqgreNa-----kqfl B Bacillus_licheniformis idlgteldivqksgawysyqeerlgqgreNa-----kqfl B Bacillus_megaterium ldiaseldivqksgswysynderlgqgreNa-----kqfl B Bacillus_subtilis idlgteldivqksgswysyeeerlgqgreNa-----kqfl B Bordetella_pertussis idlgvqanvvdksgawysysgnrigqgKdNv-----reyl B Burkholderia_fungorum idlgvqakivdkagawysysgerigqgKdNa-----refl B Chromobacterium_violaceum ielgvkhgfidksgawyayngqkigqgKdNt-----rewl B Clostridium_acetobutylicum vdvgvkeniiqksgawfsygdirlgqgreNa-----klff B Clostridium_thermocellum ldvavnldivnksgawfsyngqkigqgreNa-----kqfl B Colwellia_psychrerythraea ielgvkhefvekagawyscngerigqgKaNa-----akyl B Corynebacterium_efficiens idlavdngivkksgswftyegdqlgqgKeka-----rlfl B Desulfotalea_psychrophila fdlavgldiidksgswysyknerigqgreNs-----kqfl B Enterococcus_faecalis ldmavekdlisksgawygykeerigqgreNa-----kqym B Haemophilus_ducreyi lilaeangfiqkagawfsyngtkigqgKnNa-----ikwl B Haemophilus_influenzae lelgvkhklveksgawysyngekigqgKaNs-----mkwl B Histophilus_somni ielgvkhklvnksgawfsyegekigqgKtNa-----mkwl B Kineococcus_radiotolerans idlgvehgfvrksgawytyegdqlgqgKeNa-----rafl B Leifsonia_xyli ldfgvehalvkksgawytyegdqlgqgKeNs-----rnfl B Mannheimia_succiniciproducens ielgvkhklvdksgawyayngdkigqgKaNa-----mkwl B Nitrosomonas_europaea ielgvlhkliekagawysyngekigqgKdNv-----rdyl B Nitrosomonas_eutropha ielgvlhkliekagawysyngekigqgrdNv-----rdyl B Oceanobacillus_iheyensis ldigsdldivmksgawysynndrlgqgreNa-----kqyl B Pasteurella_multocida ielgvkhklvdkagawyayngekigqgKaNa-----mkwl B Photobacterium_profundum idlgvkhklvekagawysykgnkigqgKaNs-----ckhl B Photorhabdus_luminescens idlgvkhklvekagawysyngdkigqgKaNa-----tiyl B Proteus_mirabilis idlgvkhklvekagawysyngekigqgKaNa-----tnyl B Pseudomonas_cepacia idlgvqakivdkagawysyngekigqgKdNa-----refl B Pseudomonas_pseudomallei idlgvqakivdkagawysysgekigqgKdNa-----refl B Shewanella_amazonensis vdlgvlhklieksgawysykgdkigqgraNa-----tkfl B Shewanella_putrefaciens vdlgvahkliekagawysykgdkigqgraNa-----gkyl B Streptomyces_avermitilis idmgvengfvrkagawytyegdqlgqgKeNa-----rnfl B Vibrio_alginolyticus vdlgvkhklvekagawysyngdkigqgKaNa-----cnyl B Vibrio_angustum idlgvkhklvekagawysyqgdkigqgKaNs-----ckyl B Vibrio_cholerae idlgvkhkmveksgawysyngdkigqgKaNa-----ckyl B Vibrio_fischeri idlgvkhklvdkagawysyngdkigqgKaNa-----skfm B Vibrio_parahaemolyticus idlgvkhklvekagawysyngdkigqgKaNa-----cnyl B Vibrio_splendidus idlgvknklvekagawysykgdkigqgKsNs-----ckhl B Vibrio_vulnificus idlgvkcklieksgawysyngdkigqgKaNa-----ckyl B Yersinia_enterocolitica vdlgvkhkliekagawysyngdkigqgKaNa-----snyl B Cupriavidus_metallidurans-Q1LR74 idlgvdakivekagawysyngekigqgKdNa-----reyl B Cupriavidus_metallidurans-RECA idlgvdakivekagawysyngekigqgKdNa-----reyl B Erwinia_carotovora-RECA idlgvkhklvekagawysyngekigqgKaNa-----ttyl B Erwinia_carotovora-RECA_ERWCT vdlgvkhkliekagawysyngdkigqgKaNa-----cnfl B Listeria_monocytogenes-RECA vdmaaevdvinksgswysykeerigqgreNa-----kqyl B Listeria_monocytogenes-RECA_LISMF vdmaaevdvinksgswysykeerigqgreNa-----kqyl B Neisseria_gonorrhoeae-RECA idigvkndiinksgawysyngakigqgKdNv-----rvwl B Neisseria_gonorrhoeae-RECA_VAR idigvkndiinksgawysyngakigqgKdNv-----rvwl B Salmonella_typhi-RECA vdlgvkekliekagawysyngekigqgKaNa-----ttwl B Salmonella_typhi-RECA_SALPA vdlgvkekliekagawysyngekigqgKaNa-----ttwl B Streptomyces_coelicolor-RECA idmgvengfvrkagawytyegdqlgqgKeNa-----rnfl B Streptomyces_coelicolor-RECA_STRL idmgvengfvrkagawytyegdqlgqgKeNa-----rnfl B Xylella_fastidiosa-RECA iemgveaklvekagawysyggerigqgKdNa-----rgyl B Xylella_fastidiosa-RECA_XYLFT iemgveaklvekagawysyggerigqgKdNa-----rgyl B Yersinia_pestis-RECA vdlgvkhkliekagawysyngdkigqgKaNa-----snyl B Yersinia_pestis-RECA_YERPS vdlgvkhkliekagawysyngdkigqgKaNa-----snyl B Mycobacterium_tuberculosis-RECA idmgvdqglirksgawftyegeqlgqgKeNa-----rnfl B Mycobacterium_tuberculosis-RECA_M idmgvdqgfirksgswftyegeqlgqgKeNa-----rtfl B Neisseria_meningitidis-RECA idigvkndiinksgawysyngakigqgKdNv-----rvwl B Neisseria_meningitidis-RECA_NEIMA idigvkndiinksgawysyngakigqgKdNv-----rvwl B Neisseria_meningitidis-RECA_VAR idigvkndiinksgawysyngakigqgKdNv-----rvwl B Xanthomonas_vasicola-RECA_XANAC idmgveaklvdkagawysygderigqgKdNa-----rtyl B Xanthomonas_vasicola-RECA_XANCP idmgveaklvdkagawysygderigqgKdNa-----rgyl B Xanthomonas_vasicola-YP_201580 idmgveaklvekagawysygderigqgKdNa-----rtyl B Pseudomonas_aeruginosa-Q48F94 vdlavlhgfveksgawysyqgskigqgKaNs-----akfl B Pseudomonas_aeruginosa-RECA idlgvqlglveksgawysyqgskigqgKaNa-----akyl B Pseudomonas_aeruginosa-RECA_PSEF5 idlgvlhgfleksgawysyqgnkigqgKaNs-----akfl B Pseudomonas_aeruginosa-RECA_PSEFL idlgvlhgfveksgawyayngskigqgKaNs-----akfl B Pseudomonas_aeruginosa-RECA_PSEPK idlgvsqglveksgawyayqgnkigqgKaNa-----akyl B Pseudomonas_aeruginosa-RECA_PSEPU idlgvsqglveksgawyayqgnkigqgKaNa-----akyl B Pseudomonas_aeruginosa-RECA_PSESM vdlavlhgfveksgawysyqgskigqgKaNs-----akfl ============================================================================ B DEINOCOCCUS_RADIODURANS vglaadmdiikkagsfysygderigqgKekt-----iayi B Deinococcus_geothermalis vtlaadmdiikkagsfysygeerigqgKeka-----iayi B Thermus_aquaticus-RECA vnvavaagviekagswfsygehrlgqgKeka-----aeyl B Thermus_aquaticus-RECA_THET2 vnvavaagviekagswfsygelrlgqgKeka-----aeal B Thermus_aquaticus-RECA_THET8 vnvavaagviekagswfsygelrlgqgKeka-----aeal B Thermus_aquaticus-RECA_THETH vnvavaagviekagswfsygelrlgqgKeka-----aeal ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxexnxxxxxxxxxx 650 660 670 680 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS ---------------------------------------- A Archaeoglobus_fulgidus ---------------------------------------- A Pyrococcus_abyssi ---------------------------------------- ============================================================================ A METHANOCOCCUS_VOLTAE ---------------------------------------- A Methanococcus_jannaschii ---------------------------------------- A Methanococcus_maripaludis ---------------------------------------- ============================================================================ A SULFOLOBUS_SOLFATARICUS ---------------------------------------- A Desulfurococcus_amylolyticus ---------------------------------------- A Sulfolobus_acidocaldarius ---------------------------------------- A Sulfolobus_tokodaii ---------------------------------------- A Aeropyrum_pernix-RADA ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH3 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB6 ---------------------------------------- ============================================================================ * HUMAN ---------------------------------------- * S_CEREVISIAE ---------------------------------------- * Apis_mellifera ---------------------------------------- * Aspergillus_flavus ---------------------------------------- * Aspergillus_fumigatus ---------------------------------------- * Bovine ---------------------------------------- * C_elegans ---------------------------------------- * Candida_albicans ---------------------------------------- * Candida_glabrata ---------------------------------------- * Canis_lupus ---------------------------------------- * Chaetomium_globosum ---------------------------------------- * Coccidioides_immitis ---------------------------------------- * Coprinus_cinereus ---------------------------------------- * Cricetulus_griseus ---------------------------------------- * Cryptococcus_neoformans ---------------------------------------- * Danio_rerio ---------------------------------------- * Debaryomyces_hansenii ---------------------------------------- * D_melanogaster ---------------------------------------- * D_pseudoobscura ---------------------------------------- * Emericella_nidulans ---------------------------------------- * Encephalitozoon_cuniculi ---------------------------------------- * Eremothecium_gossypii ---------------------------------------- * Chicken ---------------------------------------- * Gibberella_zeae ---------------------------------------- * Kluyveromyces_lactis ---------------------------------------- * Mouse ---------------------------------------- * Neurospora_crassa ---------------------------------------- * Rabbit ---------------------------------------- * Pichia_angusta ---------------------------------------- * Rat ---------------------------------------- * Schizosaccharomyces_pombe ---------------------------------------- * Strongylocentrotus_purpuratus ---------------------------------------- * Tetraodon_nigroviridis ---------------------------------------- * Tribolium_castaneum ---------------------------------------- * Ustilago_maydis ---------------------------------------- * X_tropicalis ---------------------------------------- * Yarrowia_lipolytica ---------------------------------------- * X_laevis-RA51A ---------------------------------------- * X_laevis-RA51B ---------------------------------------- Cryptosporidium_hominis ---------------------------------------- Cryptosporidium_parvum ---------------------------------------- Dictyostelium_discoideum ---------------------------------------- Entamoeba_histolytica ---------------------------------------- Leishmania_donovani ---------------------------------------- Leishmania_tropica ---------------------------------------- Plasmodium_berghei ---------------------------------------- Plasmodium_falciparum ---------------------------------------- Tetrahymena_thermophila ---------------------------------------- Theileria_annulata ---------------------------------------- Theileria_parva ---------------------------------------- Trypanosoma_brucei ---------------------------------------- Trypanosoma_cruzi ---------------------------------------- P Arabidopsis_thaliana ---------------------------------------- P Oryza_sativa ---------------------------------------- P Maize-R51A1 ---------------------------------------- P Maize-R51A2 ---------------------------------------- ============================================================================ B E_COLI kdnpetakeiekkvre-l--l--ls-n------------- B MYCOBACTERIUM_SMEGMATIS lentdvaneiekkike-k--l--g---------------- B MYCOBACTERIUM_TUBERCULOSIS menddvaneiekkike-k--l--gi-g------------- B Acinetobacter_calcoaceticus eenpqisteieavire-q--l--lt-k------------- B Actinobacillus_pleuropneumoniae kenpeiaekieqdire-q--l--is-t------------- B Actinobacillus_succinogenes adnpekaaeleskira-e--f--qe-n------------- B Actinomyces_bovis lentdvrdeiekkike-k--l--g---------------- B Azotobacter_vinelandii ednpevaaaveksird-q--l--la-a------------- B Bacillus_clausii kenpeitaeierlird-h--h--gl-d----------ge- B Bacillus_halodurans kenpeaaeeiesrire-h--y--glng------------- B Bacillus_licheniformis kenkdillmiqeqire-h--y--g---------------- B Bacillus_megaterium kentdirqeiagqvre-h--h--gl-d------------- B Bacillus_subtilis kenkdimlmiqeqire-h--y--gl-d------------- B Bordetella_pertussis kehkemaieienkvre-nqgi--vs-r------------- B Burkholderia_fungorum renpdiareienrire-s--l-----g------------- B Chromobacterium_violaceum kanpaiadeierkire-a--v--gv-k------------- B Clostridium_acetobutylicum kenidirsevenkire-kydl--pi-q------------- B Clostridium_thermocellum kenpeiakeietkire-n--y--nq-t------------- B Colwellia_psychrerythraea dehpemakdvdtklrd-m--f--ls-k------------- B Corynebacterium_efficiens ketpeladeieekifr-k--l--gv-g-kf---------- B Desulfotalea_psychrophila mdtpaicheieekvrs-a--y--g---------------- B Enterococcus_faecalis adhpemmaevsklvrd-a--y--g---------------- B Haemophilus_ducreyi kenpevaekieqeirn-l--l--il-t------------- B Haemophilus_influenzae nenieksdelearlra-e--l--va-n------------- B Histophilus_somni aehpeqaaileqklrs-e--l--la-n------------- B Kineococcus_radiotolerans rdnpdlgdeiekrike-k--l--gi-g------------- B Leifsonia_xyli ianpdiaaeienkiki-k--l--g---------------- B Mannheimia_succiniciproducens aenptvaaelenkira-e--l--la-n------------- B Nitrosomonas_europaea kehksiaheieqkir------------------------- B Nitrosomonas_eutropha kehkdlaheieqkir-----------a------------- B Oceanobacillus_iheyensis keheevlteihqsirq-h--y--el-d------------- B Pasteurella_multocida eehpeealaletklrn-e--l--la-n------------- B Photobacterium_profundum venpaiaeeiekllrd-m--l--ls-p------------- B Photorhabdus_luminescens kehpevateldkklre-m--l--lh-n------------- B Proteus_mirabilis kehpemynelntklre-m--l--ln-h------------- B Pseudomonas_cepacia renpeiareienrire-s--l-----g------------- B Pseudomonas_pseudomallei renpeiareienrire-s--l-----g------------- B Shewanella_amazonensis aenteiaaeiektlre-m--l--l---------------- B Shewanella_putrefaciens tenpaiaaeidktlrell--l--sn-p------------- B Streptomyces_avermitilis kdnpdlaneiekkike-k--l--gv-gvrpeeptaepgad B Vibrio_alginolyticus rehpevaktidtklre-m--l--la-p------------- B Vibrio_angustum venpaiaaeietklrd-l--l--lt--------------- B Vibrio_cholerae kenpeiaktldkklre-m--l--ln-p------------- B Vibrio_fischeri rentevaaeldkklre-m--l--lt-p------------- B Vibrio_parahaemolyticus rehpeiaktidtklre-m--l--ls--------------- B Vibrio_splendidus renpeialeldtklre-l--l--l---------------- B Vibrio_vulnificus kenvdvakvldtklre-m--l--ls--------------- B Yersinia_enterocolitica kenpavaaeldkklre-m--l--ln-g------------- B Cupriavidus_metallidurans-Q1LR74 renpdiadeienkvrl-a--l--gv-a------------- B Cupriavidus_metallidurans-RECA renpdiadeienkvrl-a--l--gv-a------------- B Erwinia_carotovora-RECA kehpemynelntklre-m--llnh---------------- B Erwinia_carotovora-RECA_ERWCT kenptisaeldkklre-m--llhk---------------- B Listeria_monocytogenes-RECA kehtdirdeiskrvre-e--y--e---------------- B Listeria_monocytogenes-RECA_LISMF kehtdirdeiskrvre-e--y--e---------------- B Neisseria_gonorrhoeae-RECA kenpeisdeidakira-l--n--gv-e------------- B Neisseria_gonorrhoeae-RECA_VAR kenpeisdeidakira-l--n--gv-e------------- B Salmonella_typhi-RECA kenpatakeiekrvre-l--l--ls-n------------- B Salmonella_typhi-RECA_SALPA kenpatakeiekrvre-l--l--ls-n------------- B Streptomyces_coelicolor-RECA kdnpdlaneiekkikq-k--l--gv-g------------- B Streptomyces_coelicolor-RECA_STRL kdnpdlaneiekkikq-k--l--gv-g------------- B Xylella_fastidiosa-RECA renphlaakleadlre-k--f--ep-t------------- B Xylella_fastidiosa-RECA_XYLFT renphfaakleadlre-k--f--ep-t------------- B Yersinia_pestis-RECA kenpaiaaeldkklre-m--l--ln-g------------- B Yersinia_pestis-RECA_YERPS kenpaiaaeldkklre-m--l--ln-g------------- B Mycobacterium_tuberculosis-RECA venadvadeiekkike-k--l--gi-g------------- B Mycobacterium_tuberculosis-RECA_M mendevaneiekkike-k--l--gi-g------------- B Neisseria_meningitidis-RECA kenpevaneidakira-l--n--gv-e------------- B Neisseria_meningitidis-RECA_NEIMA kenpevadeidakira-l--n--gv-e------------- B Neisseria_meningitidis-RECA_VAR kenpevaneidakira-l--n--gv-e------------- B Xanthomonas_vasicola-RECA_XANAC rdnsqvatrleaelre-k--f--q---------------- B Xanthomonas_vasicola-RECA_XANCP rdnpqvaikleaelre-k--f--q---------------- B Xanthomonas_vasicola-YP_201580 rdnpqvavrleaelre-k--f--q---------------- B Pseudomonas_aeruginosa-Q48F94 adnpeickalekqird-k--l--lt-p------------- B Pseudomonas_aeruginosa-RECA ednpeigsvlektird-q--l--l---------------- B Pseudomonas_aeruginosa-RECA_PSEF5 qdnpeignalekqire-k--l--l---------------- B Pseudomonas_aeruginosa-RECA_PSEFL adnpdivatlekqird-k--l--l---------------- B Pseudomonas_aeruginosa-RECA_PSEPK aenpaigaeiekqire-k--l--l---------------- B Pseudomonas_aeruginosa-RECA_PSEPU aenpaigaeiekqird-k--l--l---------------- B Pseudomonas_aeruginosa-RECA_PSESM adnpeickalekqird-k--l--l---------------- ============================================================================ B DEINOCOCCUS_RADIODURANS aerpemeqeirdrvma-a--i--ra-g------------- B Deinococcus_geothermalis aerpeleqeirdrvla-a--i--k---------------- B Thermus_aquaticus-RECA rerpelleeirakvl------------------------- B Thermus_aquaticus-RECA_THET2 rerpelleeirtkvl------------------------- B Thermus_aquaticus-RECA_THET8 rerpelleeirakvl------------------------- B Thermus_aquaticus-RECA_THETH rerpelleeirakvl------------------------- ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 690 700 710 720 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS ---------------------------------------- A Archaeoglobus_fulgidus ---------------------------------------- A Pyrococcus_abyssi ---------------------------------------- ============================================================================ A METHANOCOCCUS_VOLTAE ---------------------------------------- A Methanococcus_jannaschii ---------------------------------------- A Methanococcus_maripaludis ---------------------------------------- ============================================================================ A SULFOLOBUS_SOLFATARICUS ---------------------------------------- A Desulfurococcus_amylolyticus ---------------------------------------- A Sulfolobus_acidocaldarius ---------------------------------------- A Sulfolobus_tokodaii ---------------------------------------- A Aeropyrum_pernix-RADA ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH3 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB6 ---------------------------------------- ============================================================================ * HUMAN ---------------------------------------- * S_CEREVISIAE ---------------------------------------- * Apis_mellifera ---------------------------------------- * Aspergillus_flavus ---------------------------------------- * Aspergillus_fumigatus ---------------------------------------- * Bovine ---------------------------------------- * C_elegans ---------------------------------------- * Candida_albicans ---------------------------------------- * Candida_glabrata ---------------------------------------- * Canis_lupus ---------------------------------------- * Chaetomium_globosum ---------------------------------------- * Coccidioides_immitis ---------------------------------------- * Coprinus_cinereus ---------------------------------------- * Cricetulus_griseus ---------------------------------------- * Cryptococcus_neoformans ---------------------------------------- * Danio_rerio ---------------------------------------- * Debaryomyces_hansenii ---------------------------------------- * D_melanogaster ---------------------------------------- * D_pseudoobscura ---------------------------------------- * Emericella_nidulans ---------------------------------------- * Encephalitozoon_cuniculi ---------------------------------------- * Eremothecium_gossypii ---------------------------------------- * Chicken ---------------------------------------- * Gibberella_zeae ---------------------------------------- * Kluyveromyces_lactis ---------------------------------------- * Mouse ---------------------------------------- * Neurospora_crassa ---------------------------------------- * Rabbit ---------------------------------------- * Pichia_angusta ---------------------------------------- * Rat ---------------------------------------- * Schizosaccharomyces_pombe ---------------------------------------- * Strongylocentrotus_purpuratus ---------------------------------------- * Tetraodon_nigroviridis ---------------------------------------- * Tribolium_castaneum ---------------------------------------- * Ustilago_maydis ---------------------------------------- * X_tropicalis ---------------------------------------- * Yarrowia_lipolytica ---------------------------------------- * X_laevis-RA51A ---------------------------------------- * X_laevis-RA51B ---------------------------------------- Cryptosporidium_hominis ---------------------------------------- Cryptosporidium_parvum ---------------------------------------- Dictyostelium_discoideum ---------------------------------------- Entamoeba_histolytica ---------------------------------------- Leishmania_donovani ---------------------------------------- Leishmania_tropica ---------------------------------------- Plasmodium_berghei ---------------------------------------- Plasmodium_falciparum ---------------------------------------- Tetrahymena_thermophila ---------------------------------------- Theileria_annulata ---------------------------------------- Theileria_parva ---------------------------------------- Trypanosoma_brucei ---------------------------------------- Trypanosoma_cruzi ---------------------------------------- P Arabidopsis_thaliana ---------------------------------------- P Oryza_sativa ---------------------------------------- P Maize-R51A1 ---------------------------------------- P Maize-R51A2 ---------------------------------------- ============================================================================ B E_COLI ------p---n--s---t---p----dfsv---d---d-- B MYCOBACTERIUM_SMEGMATIS -----------------i---g----avvt---a---e-- B MYCOBACTERIUM_TUBERCULOSIS ------a---v--v---t---d----dxs----d---d-- B Acinetobacter_calcoaceticus ------a---s--d---q---t----a-ah---d---e-- B Actinobacillus_pleuropneumoniae ------p---e--k---t---sag--eqnv---l---d-- B Actinobacillus_succinogenes ------p---e--k---t---l----iael---d---g-- B Actinomyces_bovis -----------------i---g----adlt---a---e-- B Azotobacter_vinelandii ------p---a--s---a---r----paal---a---d-- B Bacillus_clausii ------a---k--l---e---e----aae----e---q-- B Bacillus_halodurans ------e---i--e---v---e----aps----e---e-- B Bacillus_licheniformis -----------------l-dtg----gaap---a---q-- B Bacillus_megaterium ------q---d--g---e---p----ape----d---d-- B Bacillus_subtilis ------n---n--g---v---v----qqqa---e---e-- B Bordetella_pertussis ------a---a--t---f---p----asea---e---d-- B Burkholderia_fungorum ------v---n--a---m---a----eaat---v---a-- B Chromobacterium_violaceum ------i---e--i---n---e----nqg----d---e-- B Clostridium_acetobutylicum ------k---v--k---n---e----kpk----i---e-- B Clostridium_thermocellum ------f---l--m---s---i----naqv---d---t-- B Colwellia_psychrerythraea --------------------------tvva---e---d-- B Corynebacterium_efficiens ------a---q--t---a---d----elt----d---d-- B Desulfotalea_psychrophila -----------------l---p----dree---t---k-- B Enterococcus_faecalis -----------------igedg----stit---e---e-- B Haemophilus_ducreyi ------p---d--q---p---asekleldv---n---d-- B Haemophilus_influenzae ------p---e--q---a---l----madi---e---q-- B Histophilus_somni ------p---e--k---a-lla----dlea---e---s-- B Kineococcus_radiotolerans ------a---r--l---d---a----paev---d---v-- B Leifsonia_xyli -----------------i---v----adpn---a---d-- B Mannheimia_succiniciproducens ------p---e--q---a----------ll---a---d-- B Nitrosomonas_europaea -------------a---a---v----glae---t---d-- B Nitrosomonas_eutropha ------a---v--d---l---a----etn----n---r-- B Oceanobacillus_iheyensis ------k------v---d---e----dkt----e---e-- B Pasteurella_multocida ------p---e--k---v---l----aadi--ae---k-- B Photobacterium_profundum ------a---v--e---e---v----eetd---a---k-- B Photorhabdus_luminescens ------a---gefn---s---a----asdy---e---d-- B Proteus_mirabilis ------ageft--s---a---a----dfag---e---e-- B Pseudomonas_cepacia ------v---v--a---m---p----dgag---n---e-- B Pseudomonas_pseudomallei ------v---a--a---m---p----qgag---s---e-- B Shewanella_amazonensis -----------------s---h----ssss---g---s-- B Shewanella_putrefaciens ------s---a--l---a---s----sas----d---d-- B Streptomyces_avermitilis aavtsaa---a--a---t---d----dta----k---t-- B Vibrio_alginolyticus ------a---l--a--------------ea---p---e-- B Vibrio_angustum ------p---v--t---e---g----d-qv---d---e-- B Vibrio_cholerae ------e---n--mqlia---e----tssa---a---d-- B Vibrio_fischeri ------a---e--e---k---p----e------t---d-- B Vibrio_parahaemolyticus ------p------a---q---p----eapa---a---g-- B Vibrio_splendidus -----------------t---p----avle---e---k-- B Vibrio_vulnificus ------p---a--n---i---n----desa---e---l-- B Yersinia_enterocolitica ------g---n--g---e---q----pvvt---a---t-- B Cupriavidus_metallidurans-Q1LR74 ------p---l--n---t---v----agap---a---e-- B Cupriavidus_metallidurans-RECA ------p---l--n---t---v----agap---a---e-- B Erwinia_carotovora-RECA -----------------a---g----efts---a---a-- B Erwinia_carotovora-RECA_ERWCT -----------------g---n----elkp---a---a-- B Listeria_monocytogenes-RECA -----------------i---d----gsskepld---e-- B Listeria_monocytogenes-RECA_LISMF -----------------i---d----gsnkepld---e-- B Neisseria_gonorrhoeae-RECA ------m---h--i---t--------egtq---d---e-- B Neisseria_gonorrhoeae-RECA_VAR ------m---h--i---t--------egtq---d---e-- B Salmonella_typhi-RECA ------q---n--a---t---p----dfav---d---d-- B Salmonella_typhi-RECA_SALPA ------q---n--a---t---p----dfav---d---d-- B Streptomyces_coelicolor-RECA ------v---h--p---e---e----sat----epgad-- B Streptomyces_coelicolor-RECA_STRL ------v---h--p---e---e----sat----epgad-- B Xylella_fastidiosa-RECA ------e---l--s---r---e----egde---d---t-- B Xylella_fastidiosa-RECA_XYLFT ------e---l--s---r---e----egde---d---t-- B Yersinia_pestis-RECA ------g---n--g---e---q----pvaa---a---t-- B Yersinia_pestis-RECA_YERPS ------g---n--g---e---q----pvaa---a---t-- B Mycobacterium_tuberculosis-RECA ------a---v--v---t---d----dps----n---d-- B Mycobacterium_tuberculosis-RECA_M ------a---v--v---t---d----dls----d---d-- B Neisseria_meningitidis-RECA ------m---h--i---t--------egtq---d---e-- B Neisseria_meningitidis-RECA_NEIMA ------m---h--i---t--------egtq---d---e-- B Neisseria_meningitidis-RECA_VAR ------m---h--i---t--------egtq---d---e-- B Xanthomonas_vasicola-RECA_XANAC -----------------p---a----eapr---e---a-- B Xanthomonas_vasicola-RECA_XANCP -----------------p---a----eapr---e---a-- B Xanthomonas_vasicola-YP_201580 -----------------p---a----eapr---e---a-- B Pseudomonas_aeruginosa-Q48F94 ------g---v--d---t---k----avgs---r---eaa B Pseudomonas_aeruginosa-RECA ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEF5 ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEFL ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPK ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPU ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSESM ---------------------------------------- ============================================================================ B DEINOCOCCUS_RADIODURANS ------nageap---------------ala---p---a-- B Deinococcus_geothermalis -------egrdp----------------ia---a---v-- B Thermus_aquaticus-RECA ------eradkv---------------vla---------- B Thermus_aquaticus-RECA_THET2 ------eragev---------------vla---------- B Thermus_aquaticus-RECA_THET8 ------ersdqv---------------vla---------- B Thermus_aquaticus-RECA_THETH ------ersdqv---------------vla---------- ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 730 740 750 760 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ============================================================================ A PYROCOCCUS_FURIOSUS ---------------------------------------- A Archaeoglobus_fulgidus ---------------------------------------- A Pyrococcus_abyssi ---------------------------------------- ============================================================================ A METHANOCOCCUS_VOLTAE ---------------------------------------- A Methanococcus_jannaschii ---------------------------------------- A Methanococcus_maripaludis ---------------------------------------- ============================================================================ A SULFOLOBUS_SOLFATARICUS ---------------------------------------- A Desulfurococcus_amylolyticus ---------------------------------------- A Sulfolobus_acidocaldarius ---------------------------------------- A Sulfolobus_tokodaii ---------------------------------------- A Aeropyrum_pernix-RADA ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_OH3 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB1 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB2 ---------------------------------------- A Aeropyrum_pernix-RADA_VAR_TB6 ---------------------------------------- ============================================================================ * HUMAN ---------------------------------------- * S_CEREVISIAE ---------------------------------------- * Apis_mellifera ---------------------------------------- * Aspergillus_flavus ---------------------------------------- * Aspergillus_fumigatus ---------------------------------------- * Bovine ---------------------------------------- * C_elegans ---------------------------------------- * Candida_albicans ---------------------------------------- * Candida_glabrata ---------------------------------------- * Canis_lupus ---------------------------------------- * Chaetomium_globosum ---------------------------------------- * Coccidioides_immitis ---------------------------------------- * Coprinus_cinereus ---------------------------------------- * Cricetulus_griseus ---------------------------------------- * Cryptococcus_neoformans ---------------------------------------- * Danio_rerio ---------------------------------------- * Debaryomyces_hansenii ---------------------------------------- * D_melanogaster ---------------------------------------- * D_pseudoobscura ---------------------------------------- * Emericella_nidulans ---------------------------------------- * Encephalitozoon_cuniculi ---------------------------------------- * Eremothecium_gossypii ---------------------------------------- * Chicken ---------------------------------------- * Gibberella_zeae ---------------------------------------- * Kluyveromyces_lactis ---------------------------------------- * Mouse ---------------------------------------- * Neurospora_crassa ---------------------------------------- * Rabbit ---------------------------------------- * Pichia_angusta ---------------------------------------- * Rat ---------------------------------------- * Schizosaccharomyces_pombe ---------------------------------------- * Strongylocentrotus_purpuratus ---------------------------------------- * Tetraodon_nigroviridis ---------------------------------------- * Tribolium_castaneum ---------------------------------------- * Ustilago_maydis ---------------------------------------- * X_tropicalis ---------------------------------------- * Yarrowia_lipolytica ---------------------------------------- * X_laevis-RA51A ---------------------------------------- * X_laevis-RA51B ---------------------------------------- Cryptosporidium_hominis ---------------------------------------- Cryptosporidium_parvum ---------------------------------------- Dictyostelium_discoideum ---------------------------------------- Entamoeba_histolytica ---------------------------------------- Leishmania_donovani ---------------------------------------- Leishmania_tropica ---------------------------------------- Plasmodium_berghei ---------------------------------------- Plasmodium_falciparum ---------------------------------------- Tetrahymena_thermophila ---------------------------------------- Theileria_annulata ---------------------------------------- Theileria_parva ---------------------------------------- Trypanosoma_brucei ---------------------------------------- Trypanosoma_cruzi ---------------------------------------- P Arabidopsis_thaliana ---------------------------------------- P Oryza_sativa ---------------------------------------- P Maize-R51A1 ---------------------------------------- P Maize-R51A2 ---------------------------------------- ============================================================================ B E_COLI -s---------e---gv-----a--e-tn-e-----df-- B MYCOBACTERIUM_SMEGMATIS -a---------d---dv-----l--p-ap-v-----df-- B MYCOBACTERIUM_TUBERCULOSIS ---------------gv-----l--p-ap-v-----df-- B Acinetobacter_calcoaceticus -t---------e---ee-----p--d-ll-e-----s--- B Actinobacillus_pleuropneumoniae -a---------d---dv-----n--dfed-e-----af-n B Actinobacillus_succinogenes -s---------g---kn-----t--e-ld-dsedtvnf-- B Actinomyces_bovis ---------------da-----a--e-vp-a-----df-- B Azotobacter_vinelandii -e---------p----------a--d-ad-l-----dy-- B Bacillus_clausii ---------------af-----e--d-vp-l-----dl-- B Bacillus_halodurans ---------------ef-----e--d-lp-l-----dl-- B Bacillus_licheniformis -e---------d---ea-----q--aqee-l-----ef-- B Bacillus_megaterium ---------------d---------q-gd-l-----ni-- B Bacillus_subtilis -t---------q---ee-----l--e-fe-e--------- B Bordetella_pertussis -g---------e---------------------------- B Burkholderia_fungorum -s---------a---ev-----a--d-ee-e--------- B Chromobacterium_violaceum ---------------ef-----a--d-da-f-----da-- B Clostridium_acetobutylicum ---------------kg-----t--e-nn-t-----k--- B Clostridium_thermocellum -d---------d---ev-----d--l-ed-e-----e--- B Colwellia_psychrerythraea -k---------s---ev-----k--e-ke-k-----a--- B Corynebacterium_efficiens ---------------pv-----e--l-ipnv-----dfdd B Desulfotalea_psychrophila -r---------e---et---aqi--p-dt-e-----kt-- B Enterococcus_faecalis -a---------e---gq-----e--e-lp-l-----de-- B Haemophilus_ducreyi -e---------s---df-----d--e-af-e-----eq-- B Haemophilus_influenzae -s---------e---nn-----t--e-se-s-----df-- B Histophilus_somni -e---------s---ni-----s--e-ve-s-----df-- B Kineococcus_radiotolerans -e---------e---kv-------------------df-- B Leifsonia_xyli -aeptaaagsle---ek-----l--p-ar-k-----ga-- B Mannheimia_succiniciproducens -i---------e---tn-----s--e-ek-e-----df-- B Nitrosomonas_europaea -s---------r---vv-----p--p-ss-g-----e--- B Nitrosomonas_eutropha ---------------tv-----p--p-sp-s-----e--- B Oceanobacillus_iheyensis ---------------ea-----s--q-es-l-----dl-- B Pasteurella_multocida -n---------e---ss-----t--g-le-a-----dy-- B Photobacterium_profundum -k---------s---gsk----k--d-ea-e-----al-- B Photorhabdus_luminescens -n---------e---ne-----e--m-nn-e-----ef-- B Proteus_mirabilis -s---------d---sd-----a--d-dt-k-----e--- B Pseudomonas_cepacia -a---------e---am-----d--e-ee----------- B Pseudomonas_pseudomallei -a---------e---im-----d--e-ee----------- B Shewanella_amazonensis -a---------d---ev-----e-gd-en-i-----df-e B Shewanella_putrefaciens ---------------dn-----v--e-gn-i-----dl-e B Streptomyces_avermitilis ---------------vs-----a--p-aa-k-----tt-- B Vibrio_alginolyticus -a---------g---ea-----p--e-qa-e-----ef-- B Vibrio_angustum -k---------n---sd-----i--e-ed-e-----af-- B Vibrio_cholerae -d---------v---ef-----g--a-vp-e-----ef-- B Vibrio_fischeri -a---------a---pe-----i--e-en-e-----ef-- B Vibrio_parahaemolyticus -e---------k----------p--e-qe-e-----ef-- B Vibrio_splendidus -g---------a---ek-----e--e-en-e-----el-- B Vibrio_vulnificus -v---------e---em-----p--e--q-e-----ef-- B Yersinia_enterocolitica va---------d---et-----d--e-ts-e-----ef-- B Cupriavidus_metallidurans-Q1LR74 -v---------e---g------------------------ B Cupriavidus_metallidurans-RECA -v---------e---g------------------------ B Erwinia_carotovora-RECA -a---------g---nshderdfcge-gk-e-----ef-- B Erwinia_carotovora-RECA_ERWCT -a---------g---nshdedelage-gk-e-----ef-- B Listeria_monocytogenes-RECA -k---------e---et-----l--s-ll-d-----de-- B Listeria_monocytogenes-RECA_LISMF -g---------e---et-----l--s-ll-d-----de-- B Neisseria_gonorrhoeae-RECA -t---------d---g---------e-rp-e-----e--- B Neisseria_gonorrhoeae-RECA_VAR -t---------d---g---------e-rp-e-----e--- B Salmonella_typhi-RECA -s---------e---gv-----a--e-tn-e-----df-- B Salmonella_typhi-RECA_SALPA -s---------e---gv-----a--e-tn-e-----df-- B Streptomyces_coelicolor-RECA ---------------aa-----s--a-ap-a-----da-- B Streptomyces_coelicolor-RECA_STRL ---------------aa-----s--a-ap-a-----da-- B Xylella_fastidiosa-RECA -l---------e---dt-----m----------------- B Xylella_fastidiosa-RECA_XYLFT -l---------e---da-----m----------------- B Yersinia_pestis-RECA -a---------efadga-----d--e-tn-e-----ef-- B Yersinia_pestis-RECA_YERPS -a---------efadgv-----d--e-tn-e-----ef-- B Mycobacterium_tuberculosis-RECA ---------------gv-----l--p-ap-v-----df-- B Mycobacterium_tuberculosis-RECA_M ---------------gv-----l--p-ap-v-----df-- B Neisseria_meningitidis-RECA -t---------d---g---------e-rp-e-----e--- B Neisseria_meningitidis-RECA_NEIMA -t---------d---g---------e-rp-e-----e--- B Neisseria_meningitidis-RECA_VAR -t---------d---g---------e-rp-e-----e--- B Xanthomonas_vasicola-RECA_XANAC -g---------d---de-----d--k-e------------ B Xanthomonas_vasicola-RECA_XANCP -g---------e---te-----s--e-e------------ B Xanthomonas_vasicola-YP_201580 -g---------d---de-----e--k-e------------ B Pseudomonas_aeruginosa-Q48F94 va---------d---dm-----a--e-ad-a-----di-- B Pseudomonas_aeruginosa-RECA ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEF5 ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEFL ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPK ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSEPU ---------------------------------------- B Pseudomonas_aeruginosa-RECA_PSESM ---------------------------------------- ============================================================================ B DEINOCOCCUS_RADIODURANS -paapeaae---------------------a--------- B Deinococcus_geothermalis -petpalae------------------------------- B Thermus_aquaticus-RECA --ageeege------------------------------- B Thermus_aquaticus-RECA_THET2 --agedege------------------------------- B Thermus_aquaticus-RECA_THET8 --agedege------------------------------- B Thermus_aquaticus-RECA_THETH --agedege------------------------------- ============================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 770 780 790 800 ----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxx =========================================================== A PYROCOCCUS_FURIOSUS ----------------------- A Archaeoglobus_fulgidus ----------------------- A Pyrococcus_abyssi ----------------------- =========================================================== A METHANOCOCCUS_VOLTAE ----------------------- A Methanococcus_jannaschii ----------------------- A Methanococcus_maripaludis ----------------------- =========================================================== A SULFOLOBUS_SOLFATARICUS ----------------------- A Desulfurococcus_amylolyticus ----------------------- A Sulfolobus_acidocaldarius ----------------------- A Sulfolobus_tokodaii ----------------------- A Aeropyrum_pernix-RADA ----------------------- A Aeropyrum_pernix-RADA_VAR_OH1 ----------------------- A Aeropyrum_pernix-RADA_VAR_OH2 ----------------------- A Aeropyrum_pernix-RADA_VAR_OH3 ----------------------- A Aeropyrum_pernix-RADA_VAR_TB1 ----------------------- A Aeropyrum_pernix-RADA_VAR_TB2 ----------------------- A Aeropyrum_pernix-RADA_VAR_TB6 ----------------------- =========================================================== * HUMAN ----------------------- * S_CEREVISIAE ----------------------- * Apis_mellifera ----------------------- * Aspergillus_flavus ----------------------- * Aspergillus_fumigatus ----------------------- * Bovine ----------------------- * C_elegans ----------------------- * Candida_albicans ----------------------- * Candida_glabrata ----------------------- * Canis_lupus ----------------------- * Chaetomium_globosum ----------------------- * Coccidioides_immitis ----------------------- * Coprinus_cinereus ----------------------- * Cricetulus_griseus ----------------------- * Cryptococcus_neoformans ----------------------- * Danio_rerio ----------------------- * Debaryomyces_hansenii ----------------------- * D_melanogaster ----------------------- * D_pseudoobscura ----------------------- * Emericella_nidulans ----------------------- * Encephalitozoon_cuniculi ----------------------- * Eremothecium_gossypii ----------------------- * Chicken ----------------------- * Gibberella_zeae ----------------------- * Kluyveromyces_lactis ----------------------- * Mouse ----------------------- * Neurospora_crassa ----------------------- * Rabbit ----------------------- * Pichia_angusta ----------------------- * Rat ----------------------- * Schizosaccharomyces_pombe ----------------------- * Strongylocentrotus_purpuratus ----------------------- * Tetraodon_nigroviridis ----------------------- * Tribolium_castaneum ----------------------- * Ustilago_maydis ----------------------- * X_tropicalis ----------------------- * Yarrowia_lipolytica ----------------------- * X_laevis-RA51A ----------------------- * X_laevis-RA51B ----------------------- Cryptosporidium_hominis ----------------------- Cryptosporidium_parvum ----------------------- Dictyostelium_discoideum ----------------------- Entamoeba_histolytica ----------------------- Leishmania_donovani ----------------------- Leishmania_tropica ----------------------- Plasmodium_berghei ----------------------- Plasmodium_falciparum ----------------------- Tetrahymena_thermophila ----------------------- Theileria_annulata ----------------------- Theileria_parva ----------------------- Trypanosoma_brucei ----------------------- Trypanosoma_cruzi ----------------------- P Arabidopsis_thaliana ----------------------- P Oryza_sativa ----------------------- P Maize-R51A1 ----------------------- P Maize-R51A2 ----------------------- =========================================================== B E_COLI ----------------------- B MYCOBACTERIUM_SMEGMATIS ----------------------- B MYCOBACTERIUM_TUBERCULOSIS ----------------------- B Acinetobacter_calcoaceticus ----------------------- B Actinobacillus_pleuropneumoniae eeel------------------- B Actinobacillus_succinogenes --e-------------------- B Actinomyces_bovis ----------------------- B Azotobacter_vinelandii ----------------------- B Bacillus_clausii k---------------------- B Bacillus_halodurans k---------------------- B Bacillus_licheniformis ----------------------- B Bacillus_megaterium ----------------------- B Bacillus_subtilis ----------------------- B Bordetella_pertussis ----------------------- B Burkholderia_fungorum ----------------------- B Chromobacterium_violaceum ----------------------- B Clostridium_acetobutylicum ----------------------- B Clostridium_thermocellum ----------------------- B Colwellia_psychrerythraea ----------------------- B Corynebacterium_efficiens edddfdastapagtftevtten- B Desulfotalea_psychrophila -kdv------------------- B Enterococcus_faecalis ----------------------- B Haemophilus_ducreyi --e-------------------- B Haemophilus_influenzae --e-------------------- B Histophilus_somni ----------------------- B Kineococcus_radiotolerans ----------------------- B Leifsonia_xyli ----------------------- B Mannheimia_succiniciproducens --e-------------------- B Nitrosomonas_europaea ----------------------- B Nitrosomonas_eutropha ----------------------- B Oceanobacillus_iheyensis k---------------------- B Pasteurella_multocida ----------------------- B Photobacterium_profundum --k-------------------- B Photorhabdus_luminescens ----------------------- B Proteus_mirabilis ----------------------- B Pseudomonas_cepacia ----------------------- B Pseudomonas_pseudomallei ----------------------- B Shewanella_amazonensis tgevf------------------ B Shewanella_putrefaciens tgevf------------------ B Streptomyces_avermitilis -----kskaaaaks--------- B Vibrio_alginolyticus ----------------------- B Vibrio_angustum ----------------------- B Vibrio_cholerae ----------------------- B Vibrio_fischeri ----------------------- B Vibrio_parahaemolyticus ----------------------- B Vibrio_splendidus ----------------------- B Vibrio_vulnificus ----------------------- B Yersinia_enterocolitica ----------------------- B Cupriavidus_metallidurans-Q1LR74 ----------------------- B Cupriavidus_metallidurans-RECA ----------------------- B Erwinia_carotovora-RECA ----------------------- B Erwinia_carotovora-RECA_ERWCT ----------------------- B Listeria_monocytogenes-RECA ----------------------- B Listeria_monocytogenes-RECA_LISMF ----------------------- B Neisseria_gonorrhoeae-RECA ----------------------- B Neisseria_gonorrhoeae-RECA_VAR ----------------------- B Salmonella_typhi-RECA ----------------------- B Salmonella_typhi-RECA_SALPA ----------------------- B Streptomyces_coelicolor-RECA -apavpapttakatkskataaks B Streptomyces_coelicolor-RECA_STRL -apavpapttakatkskaaaaks B Xylella_fastidiosa-RECA ----------------------- B Xylella_fastidiosa-RECA_XYLFT ----------------------- B Yersinia_pestis-RECA ----------------------- B Yersinia_pestis-RECA_YERPS ----------------------- B Mycobacterium_tuberculosis-RECA ----------------------- B Mycobacterium_tuberculosis-RECA_M ----------------------- B Neisseria_meningitidis-RECA ----------------------- B Neisseria_meningitidis-RECA_NEIMA ----------------------- B Neisseria_meningitidis-RECA_VAR ----------------------- B Xanthomonas_vasicola-RECA_XANAC ----------------------- B Xanthomonas_vasicola-RECA_XANCP ----------------------- B Xanthomonas_vasicola-YP_201580 ----------------------- B Pseudomonas_aeruginosa-Q48F94 ----------------------- B Pseudomonas_aeruginosa-RECA ----------------------- B Pseudomonas_aeruginosa-RECA_PSEF5 ----------------------- B Pseudomonas_aeruginosa-RECA_PSEFL ----------------------- B Pseudomonas_aeruginosa-RECA_PSEPK ----------------------- B Pseudomonas_aeruginosa-RECA_PSEPU ----------------------- B Pseudomonas_aeruginosa-RECA_PSESM ----------------------- =========================================================== B DEINOCOCCUS_RADIODURANS ----------------------- B Deinococcus_geothermalis ----------------------- B Thermus_aquaticus-RECA ----------------------- B Thermus_aquaticus-RECA_THET2 ----------------------- B Thermus_aquaticus-RECA_THET8 ----------------------- B Thermus_aquaticus-RECA_THETH ----------------------- =========================================================== Consensus 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