10 20 30 40 50 60 70 ----:----|----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus axxepxxexsxsxspxxxekekxexxssqeixnpExyikHPLqSRWaLWFfKndkxxskTWqanLRlISkFdTVE ==================================================================================================== * HUMAN AtvEP--EtTpTpNPpttEEEKtE--SNQEVaNPEhYIKHPLQNRWALWFFKNDK--SKTWQANLRLISKFDTVE * MOUSE AtvEP--EtTpTtNPppaEEEKtE--SNQEVaNPEhYIKHPLQNRWALWFFKNDK--SKTWQANLRLISKFDTVE * Bovine AtvEP--EtTpTpNPpptEEEKtE--SNQEVaNPEhYIKHPLQNRWALWFFKNDK--SKTWQANLRLISKFDTVE * Chicken llvnPffKqetTpNPqpsEEEKtEpapTQEVaSPEqYIKHPLQNRWALWFFKNDK--SKTWQANLRLISKFDTVE * Oryzias_latipes ---ta--vvvsTsiPgnlEEKsei--SNgKIgNPEacIKHPLQNRWtLWFFKNDK--SKTWQANLRLIStFDTVE * Pan_troglodytes AtvEP--EtTpTpNPpttgEEKtE--SNQEVaNPEhYIKHPLQNRWALWFFKNDK--SKTsQANLwLISKFDTVE * Tetraodon_nigroviridis AtaEP--EpNrSlSqp-dEEEseE--TgQELvraDpYIKHPLQNRWcLWFFKNDK--SKTWQANLRLISKFDTVE * X_laevis AavEP--EnT---NPqstEEEK-E--TgQEIvSPDqYIKHPLQNRWALWFFKNDK--SKTWQANLRLISKFDTVE * X_tropicalis AsvEP--EgT---NPqstEEEKtE--TSQEIvSPDqYIKHPLQNRWALWFFKNDK--SKTWQANLRLISKFDTVE * Danio_rerio-IF4EA AtaEP--EtStNpS-nseEKineE--NeQQIvSlEdYIKHPLQNRWALWFFKNDK--SKTWQANLRLISKFDTVE * Danio_rerio-Q5RKQ5 AtaEP--EiksNsc-kseEEisdE--SNQEIvSPEsYIKHPLQNRWcLWFFKNDK--SKTWQANLRLISKFDTVE ==================================================================================================== * S_CEREVISIAE --sveevskkfeeNvsvdDttatpktvlsDsaHfD--VKHPLnTKWtLWYtKpavdkSESWsdlLRpVTsFqTVE * Candida_glabrata --svdevtkkfeeTvsvdg----pktvlsDakDfE--VKHPLnTKWtLWYtKpavdkSESWsdlLRpVTsFqSVE * Eremothecium_gossypii --sveevtqk-aqalsvgDnEEr-kavltDskDfD--LKHPLnSKWtLWYtKppvgdNESWsdlLRpVTsFtTVE ==================================================================================================== Consensus axxepxxexsxsxspxxxekekxexxssqeixnpExyikHPLqSRWaLWFfKndkxxskTWqanLRlISkFdTVE 80 90 100 110 120 130 140 150 ----|----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus DFWALyNHIqlssnLmxgcDYsLFKDgIePmWEDErNkRGGRWlitLnkqqrkxdldrfwletllclvgexfDDy ==================================================================================================== * HUMAN DFWALYNHIQLSSNLMpGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRsDLDRFWLETLLCLIGEsFDDY * MOUSE DFWALYNHIQLSSNLMpGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRsDLDRFWLETLLCLIGEsFDDY * Bovine DFWALYNHIQLSSNLMpGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRgDLDRFWLETLLCLIGEsFDDY * Chicken DFWALYNHIQLSSNLMpGCDYSLFKDGIEPMWEDEKNKRGGRWLITLtKQQRRsDLDRFWLETLLCLIGEsFDDY * Oryzias_latipes DFWALYNHIQLSSNLMsGCDYSLFKDGIEPMWEDERNRRGGRWLITLSKhQRKmDLDRFWLETLLCLVGEaFDDh * Pan_troglodytes DFWALYNHIQLSSNLMpGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRsDLDRFWLETLLCLIGEsFDDY * Tetraodon_nigroviridis DFWALYNHIQLSSNLMsGCDYSLFKDeIEPMWEDERNKRGGRWLITLNKQQRRfDLDRFWLETLLCLVGEaFDDY * X_laevis DFWALYNHIQLSSNLMsGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRnDLDRFWLETLMCLIGEsFDEh * X_tropicalis DFWALYNHIQLSSNLMsGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRnDLDRFWLETLMCLIGEsFDEY * Danio_rerio-IF4EA DFWALYNHIQLSSNLMsGCDYSLFKDGIEPMWEDERNKRGGRWLITLSKQQRRaDLDRFWLETLLCLVGEaFDDh * Danio_rerio-Q5RKQ5 DFWALYNHIQLSSNLMsGCDYSLFKDGIEPMWEDERNKRGGRWLITLNKQQRKyDLDRFWLETLLCLIGEaFDDY ==================================================================================================== * S_CEREVISIAE EFWAIiqNIpepheLplksDYhVFRNdVrPeWEDEaNaKGGKWsfqLrgKgadiDelwlrtllaVigeti--DEd * Candida_glabrata EFWAIvqNIpepheLplksDYhVFRNdIrPeWEDsaNaKGGKWsfqVrgRgaEiDelwlrtllaVigeti--DEe * Eremothecium_gossypii EFWAIqNaIpkpreLplksDYhLFRNdIrPeWEDEaNsRGGKWsfqfkvRnppiDdlwlrallaVigesi--DEd ==================================================================================================== Consensus DFWALyNHIqlssnLmxgcDYsLFKDgIePmWEDErNkRGGRWlitLnkqqrkxdldrfwletllclvgexfDDy 160 170 180 190 200 210 220 ----:----|----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus sdEVcGaVVNIRakGDKIAIWTtdxeNKDaITnIGrvYKErLgVpxEviIgYqsHadtatKngsttKnkfVV ================================================================================================= * HUMAN SDDVCGAVVNVRAKGDKIAIWTTEcENREAVTHIGRVYKERLGLPpKIVIGYQSHADTATKSGSTTKNRFVV * MOUSE SDDVCGAVVNVRAKGDKIAIWTTEcENRDAVTHIGRVYKERLGLPpKIVIGYQSHADTATKSGSTTKNRFVV * Bovine SDDVCGAVVNVRAKGDKIAIWTTEcENREAVTHIGRVYKERLGLPpKIVIGYQSHADTATKSGSTTKNRFVV * Chicken SDDVCGAVVNVRtKGDKIAIWTTEcENRDAVTHIGRVYKERLGLPpKIVIGYQSHADTATKSGSTTKNRFVV * Oryzias_latipes SDDVCGAVINIRAKGDKIAIWTTNcENKEAITqIGRVYKERLGVPpKVIIGYQSHADTATKSsSTTKNKFVa * Pan_troglodytes SDDVCGAVVNVRAKGDKIAIWTTEcENREAVTHIGRVYKERLGLPpKIVIGYQSHADTATKSGSTTKNRFVV * Tetraodon_nigroviridis SDDVCGAVVNVRAKGDKIAIWTaNyENRDAVTHIGKVYKERLGLPmKMtIGYQSHtDTATKSGSTTKNKYVV * X_laevis SDDVCGAVVNVRAKGDKIAIWTTEfENKDAVTHIGRVYKERLGLPaKVVIGYQSHADTATKSGSTTKNRFVV * X_tropicalis SDDVCGAVVNVRAKGDKIAIWTTEfENRDAVTHIGKVYKERLGLPaKVVIGYQSHADTATKSGSTTKNRFVV * Danio_rerio-IF4EA SDDVCGAVVNIRtKGDKIAIWTTDyENKDAIvHIGRVYKERLGVPpKVIIGYQSHADTATKSGSTTKNKFVV * Danio_rerio-Q5RKQ5 SDDVCGAVVNVRtKGDKIAIWTaDygNREAVTHIGRVYKERLGVPmnMtIGYQSHADTATKSGSTTKNKFVV ================================================================================================= * S_CEREVISIAE dsQInGvVLSIRkgGNKfALWTkse-DKEpLlrIGgkFKQvLkLtdDghLeFfpHssangRHp---QpsitL * Candida_glabrata dsQInGvVLNVRkgGNRfALWTksc-DKEpLSNIGarFKQvLkLadEdtLeFfpHstandRHs---QptitL * Eremothecium_gossypii efEInGvVINVRrsGfKIgLWTksv-rQapLSkVGakFKavLqLddsdtLeFfaHssandKNa---KpalVL ================================================================================================= Consensus sdEVcGaVVNIRakGDKIAIWTtdxeNKDaITnIGrvYKErLgVpxEviIgYqsHadtatKngsttKnkfVV
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