10 20 30 40
----:----|----:----|----:----|----:----|----:
Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
===============================================================================
* S_CEREVISIAE ---------------------------------------------
* Candida_albicans ---------------------------------------------
* Candida_glabrata ---------------------------------------------
* Debaryomyces_hansenii ---------------------------------------------
* Eremothecium_gossypii ---------------------------------------------
* Yarrowia_lipolytica ---------------------------------------------
* Zygosaccharomyces_bailii ---------------------------------------------
* Kluyveromyces_lactis-TPIS ---------------------------------------------
* Kluyveromyces_lactis-TPIS_KLUMA ---------------------------------------------
===============================================================================
* C_ELEGANS ---------------------------------------------
* HUMAN ---------------------------------------------
* RABBIT ---------------------------------------------
* CHICKEN ---------------------------------------------
* 1SPQA_Chicken ---------------------------------------------
* 1SPQB_Chicken ---------------------------------------------
* 1SQ7A_Chicken ---------------------------------------------
* 1SSDA_Chicken ---------------------------------------------
* 1SU5A_Chicken ---------------------------------------------
* 1SW3A_Chicken ---------------------------------------------
* 1SW7A_Chicken ---------------------------------------------
* 1TPB1_Chicken ---------------------------------------------
* 1TPC1_Chicken ---------------------------------------------
* 1TPUA_Chicken ---------------------------------------------
* 1TPVA_Chicken ---------------------------------------------
* 1TPWA_Chicken ---------------------------------------------
* Acipenser_brevirostrum ---------------------------------------------
* Anopheles_gambiae ---------------------------------------------
* Bovine ---------------------------------------------
* C_briggsae ---------------------------------------------
* Canis_lupus ---------------------------------------------
* Danio_rerio ---------------------------------------------
* Gorilla_gorilla ---------------------------------------------
* Latimeria_chalumnae ---------------------------------------------
* Lepisosteus_osseus ---------------------------------------------
* Macaca_mulatta ---------------------------------------------
* Mouse ---------------------------------------------
* Oryzias_latipes ---------------------------------------------
* Pongo_pygmaeus ---------------------------------------------
* Schistosoma_mansoni ---------------------------------------------
* Strongylocentrotus_purpuratus ---------------------------------------------
* Pig ---------------------------------------------
* Tribolium_castaneum ---------------------------------------------
* X_laevis ---------------------------------------------
* D_melanogaster-TPIS ppgvlndlnrngiqciasvtllqrfpyhrnhhtiptmdqnrptvg
* D_melanogaster-TPIS_VAR ppgvlndlnrngiqciasvtllqrfpyhrnhhtiptmdqnrptvg
* Rat-Q6P793 ---------------------------------------------
* Rat-TPIS ---------------------------------------------
===============================================================================
ENTAMOEBA_HISTOLYTICA ---------------------------------------------
===============================================================================
LEISHMANIA_MEXICANA ---------------------------------------------
TRYPANOSOMA_CRUZI ---------------------------------------------
TRYPANOSOMA_BRUCEI ---------------------------------------------
1KV5A_Trypanosoma_brucei ---------------------------------------------
1MSSA_Trypanosoma_brucei ---------------------------------------------
1TRI0_Trypanosoma_brucei ---------------------------------------------
1TTI0_Trypanosoma_brucei ---------------------------------------------
1TTJ0_Trypanosoma_brucei ---------------------------------------------
Leishmania_donovani ---------------------------------------------
Leishmania_tropica ---------------------------------------------
===============================================================================
PLASMODIUM_FALCIPARUM ---------------------------------------------
1VGAB_Plasmodium_falciparum ---------------------------------------------
Plasmodium_berghei ---------------------------------------------
Plasmodium_chabaudi ---------------------------------------------
===============================================================================
B E_COLI ---------------------------------------------
B VIBRIO_MARINUS ---------------------------------------------
B Actinobacillus_pleuropneumoniae ---------------------------------------------
B Actinobacillus_succinogenes ---------------------------------------------
B Erwinia_carotovora ---------------------------------------------
B Haemophilus_ducreyi ---------------------------------------------
B Haemophilus_influenzae ---------------------------------------------
B Histophilus_somni ---------------------------------------------
B Mannheimia_succiniciproducens ---------------------------------------------
B Pasteurella_multocida ---------------------------------------------
B Photobacterium_profundum ---------------------------------------------
B Photorhabdus_luminescens ---------------------------------------------
B Vibrio_cholerae ---------------------------------------------
B Vibrio_fischeri ---------------------------------------------
B Vibrio_parahaemolyticus ---------------------------------------------
B Vibrio_vulnificus ---------------------------------------------
B Yersinia_pestis ---------------------------------------------
B Salmonella_typhi-TPIS ---------------------------------------------
B Salmonella_typhi-TPIS_SALTY ---------------------------------------------
===============================================================================
B THERMUS_AQUATICUS ---------------------------------------------
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS ---------------------------------------------
B Bacillus_clausii ---------------------------------------------
B Bacillus_halodurans ---------------------------------------------
B Bacillus_licheniformis ---------------------------------------------
B Bacillus_megaterium ---------------------------------------------
B Bacillus_subtilis ---------------------------------------------
B Listeria_monocytogenes-TPIS1 ---------------------------------------------
B Listeria_monocytogenes-TPIS1_LI ---------------------------------------------
===============================================================================
Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
50 60 70 80 90
----|----:----|----:----|----:----|----:----|
Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
===============================================================================
* S_CEREVISIAE ---------------------------------------------
* Candida_albicans ---------------------------------------------
* Candida_glabrata ---------------------------------------------
* Debaryomyces_hansenii ---------------------------------------------
* Eremothecium_gossypii ---------------------------------------------
* Yarrowia_lipolytica ---------------------------------------------
* Zygosaccharomyces_bailii ---------------------------------------------
* Kluyveromyces_lactis-TPIS ---------------------------------------------
* Kluyveromyces_lactis-TPIS_KLUMA ---------------------------------------------
===============================================================================
* C_ELEGANS ---------------------------------------------
* HUMAN ---------------------------------------------
* RABBIT ---------------------------------------------
* CHICKEN ---------------------------------------------
* 1SPQA_Chicken ---------------------------------------------
* 1SPQB_Chicken ---------------------------------------------
* 1SQ7A_Chicken ---------------------------------------------
* 1SSDA_Chicken ---------------------------------------------
* 1SU5A_Chicken ---------------------------------------------
* 1SW3A_Chicken ---------------------------------------------
* 1SW7A_Chicken ---------------------------------------------
* 1TPB1_Chicken ---------------------------------------------
* 1TPC1_Chicken ---------------------------------------------
* 1TPUA_Chicken ---------------------------------------------
* 1TPVA_Chicken ---------------------------------------------
* 1TPWA_Chicken ---------------------------------------------
* Acipenser_brevirostrum ---------------------------------------------
* Anopheles_gambiae ---------------------------------------------
* Bovine ---------------------------------------------
* C_briggsae ---------------------------------------------
* Canis_lupus ---------------------------------------------
* Danio_rerio ---------------------------------------------
* Gorilla_gorilla ---------------------------------------------
* Latimeria_chalumnae ---------------------------------------------
* Lepisosteus_osseus ---------------------------------------------
* Macaca_mulatta ---------------------------------------------
* Mouse ---------------------------------------------
* Oryzias_latipes ---------------------------------------------
* Pongo_pygmaeus ---------------------------------------------
* Schistosoma_mansoni ---------------------------------------------
* Strongylocentrotus_purpuratus -----------------------------------------a---
* Pig ---------------------------------------------
* Tribolium_castaneum -------------------aevdpactpi--kigsgpd---aklh
* X_laevis ---------------------------------------------
* D_melanogaster-TPIS gvtaevlkavvseallgkftavfpklfkcqwktyegqkkfyanfs
* D_melanogaster-TPIS_VAR gvtaevlkavvseallgkftavfpklfkcqwktyegqkkfyanfs
* Rat-Q6P793 ---------------------------------------------
* Rat-TPIS ---------------------------------------------
===============================================================================
ENTAMOEBA_HISTOLYTICA ---------------------------------------------
===============================================================================
LEISHMANIA_MEXICANA ---------------------------------------------
TRYPANOSOMA_CRUZI ---------------------------------------------
TRYPANOSOMA_BRUCEI ---------------------------------------------
1KV5A_Trypanosoma_brucei ---------------------------------------------
1MSSA_Trypanosoma_brucei ---------------------------------------------
1TRI0_Trypanosoma_brucei ---------------------------------------------
1TTI0_Trypanosoma_brucei ---------------------------------------------
1TTJ0_Trypanosoma_brucei ---------------------------------------------
Leishmania_donovani ---------------------------------------------
Leishmania_tropica ---------------------------------------------
===============================================================================
PLASMODIUM_FALCIPARUM ---------------------------------------------
1VGAB_Plasmodium_falciparum ---------------------------------------------
Plasmodium_berghei ---------------------------------------------
Plasmodium_chabaudi ---------------------------------------------
===============================================================================
B E_COLI ---------------------------------------------
B VIBRIO_MARINUS ---------------------------------------------
B Actinobacillus_pleuropneumoniae ---------------------------------------------
B Actinobacillus_succinogenes ---------------------------------------------
B Erwinia_carotovora ---------------------------------------------
B Haemophilus_ducreyi ---------------------------------------------
B Haemophilus_influenzae ---------------------------------------------
B Histophilus_somni ---------------------------------------------
B Mannheimia_succiniciproducens ---------------------------------------------
B Pasteurella_multocida ---------------------------------------------
B Photobacterium_profundum ---------------------------------------------
B Photorhabdus_luminescens ---------------------------------------------
B Vibrio_cholerae ---------------------------------------------
B Vibrio_fischeri ---------------------------------------------
B Vibrio_parahaemolyticus ---------------------------------------------
B Vibrio_vulnificus ---------------------------------------------
B Yersinia_pestis ---------------------------------------------
B Salmonella_typhi-TPIS ---------------------------------------------
B Salmonella_typhi-TPIS_SALTY ---------------------------------------------
===============================================================================
B THERMUS_AQUATICUS ---------------------------------------------
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS ---------------------------------------------
B Bacillus_clausii ---------------------------------------------
B Bacillus_halodurans ---------------------------------------------
B Bacillus_licheniformis ---------------------------------------------
B Bacillus_megaterium ---------------------------------------------
B Bacillus_subtilis ---------------------------------------------
B Listeria_monocytogenes-TPIS1 ---------------------------------------------
B Listeria_monocytogenes-TPIS1_LI ---------------------------------------------
===============================================================================
Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
100 110 120 130
----:----|----:----|----:----|----:----|----:
Consensus xxxxxxxxxxxxxRQfxVxGNWKMNgnKxnLxELIxxLNxxxxxx
===============================================================================
* S_CEREVISIAE ------------aRtFfVgGNFKLNGSKqSIkEIVerLNt---as
* Candida_albicans ------------aRQFfVgGNFKaNGtKqqItsIIdnLNk---ad
* Candida_glabrata ------------aRtFfVgGNFKLNGtKkSIkEIVdrLNt---as
* Debaryomyces_hansenii ------------aRQFfVgGNFKMNGtReSVsKIVdgLNk---ae
* Eremothecium_gossypii ------------aRtFfVgGNFKLNGSKqSIkEIVerLNt---ad
* Yarrowia_lipolytica ------------sRtFfVgGNFKMNGSleSIkaIVerLNa---se
* Zygosaccharomyces_bailii ------------aRtFfVgGNFKLNGtKsSIkEIVerLNn---ak
* Kluyveromyces_lactis-TPIS ------------aRtFfIgGNFKMNGSKaSIkEIVdrLNg---as
* Kluyveromyces_lactis-TPIS_KLUMA ------------aRtFfIgGNFKMNGtKaSIkEIVerLNs---as
===============================================================================
* C_ELEGANS ------------tRKFfVgGNWKMNGDyaSVdgIVtfLNa---sa
* HUMAN ----------apsRKFfVgGNWKMNGrKqSLgELIgtLNa---ak
* RABBIT ----------apsRKFfVgGNWKMNGrKkNLgELIttLNa---ak
* CHICKEN ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SPQA_Chicken -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SPQB_Chicken ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SQ7A_Chicken ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SSDA_Chicken ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SU5A_Chicken ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SW3A_Chicken ----------ap-RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1SW7A_Chicken -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPB1_Chicken -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPC1_Chicken -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPUA_Chicken -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPVA_Chicken -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* 1TPWA_Chicken -------------RKFfVgGNWKMNGDKkSLgELIhtLNg---ak
* Acipenser_brevirostrum ----------aptRKFfVgGNWKLNGDKkSLgELIhtLNs---gk
* Anopheles_gambiae -----------g-RKFcVgGNWKMNGDKaSItELcktLSa---gp
* Bovine ----------apsRKFfVgGNWKMNGrKnNLgELIntLNa---ak
* C_briggsae -----------a-RKFfVgGNWKMNGDfaSVdgIVafLNq---sa
* Canis_lupus ----------apsRKFfVgGNWKMNGrKkNLgELIttLNa---ak
* Danio_rerio ----------sg-RKFfVgGNWKMNGDKkSIeELantLNs---ak
* Gorilla_gorilla ----------apsRKFfVgGNWKMNGrKqSLgELIgtLNa---ak
* Latimeria_chalumnae ----------ap-RKFfVgGNWKMNGDKkSLgELIqtLNa---ak
* Lepisosteus_osseus --------------------------DKkvLgDLIntLNt---ak
* Macaca_mulatta ----------apsRKFfVgGNWKMNGrKqNLgELIgtLNa---ak
* Mouse ----------aptRKFfVgGNWKMNGrKkcLgELIctLNa---an
* Oryzias_latipes ----------aq-RRFfVgGNWKMNGNKeSLeELMstLNt---as
* Pongo_pygmaeus ----------apsRKFfVgGNWKMNGrKqSLgELIgtLNa---ak
* Schistosoma_mansoni ---s------gs-RKFfVgGNWKMNGSRdDndKLLklLSe---ah
* Strongylocentrotus_purpuratus ----------sg-RRFwVgGNYKMNGSKaSIdgLLkmLee---sq
* Pig ----------apaRKFfVgGNWKMNGrKnNLgELIntLNa---ak
* Tribolium_castaneum cscs------mg-RKFvVgGNWKMNGDKkqIsEIIntLkt---gp
* X_laevis ----------sp-RKFfVgGNWKMNGDKkSLgELIntLNs---gk
* D_melanogaster-TPIS tdctdsnsnnms-RKFcVgGNWKMNGDQkSIaEIaktLSs---aa
* D_melanogaster-TPIS_VAR tdctdsnsnnms-RKFcVgGNWKMNGDQkSIaEIaktLSs---aa
* Rat-Q6P793 ----------apsRKFfVgGNWKMNGrKkcLgELIctLNa---ak
* Rat-TPIS ----------apsRKFfVgGNWKMNGrKkcLgELIctLNa---ak
===============================================================================
ENTAMOEBA_HISTOLYTICA -----------gagKFvVgGNWKcNGtlaSIetLtkgVaasvdae
===============================================================================
LEISHMANIA_MEXICANA ----------sakpQpiaaaNWKcNGttaSIeKLVqvfNe---ht
TRYPANOSOMA_CRUZI ----------askpQpiaaaNWKcNGSEslLvpLIetLNa---at
TRYPANOSOMA_BRUCEI -----------skpQpiaaaNWKcNGSQqSLsELIdlfNs---ts
1KV5A_Trypanosoma_brucei -----------skpQpiaaaNWKcNGSQqSLsELIdlfNs---ts
1MSSA_Trypanosoma_brucei -----------skpQpiaaaNWKcNGSQqSLsELIdlfNs---ts
1TRI0_Trypanosoma_brucei -----------skpQpiaaaNW---GSQqSLsELIdlfNs---ts
1TTI0_Trypanosoma_brucei -----------skpQpiaaaNWK------SLsELIdlfNs---ts
1TTJ0_Trypanosoma_brucei -----------skpQpiaaaNW-------SLsELIdlfNs---ts
Leishmania_donovani ----------sskpQpiaaaNWKcNGttaSIeKLVqvLNe---hn
Leishmania_tropica ----------sakpQpiaaaNWKcNGttaSIeKLVqvLNe---hn
===============================================================================
PLASMODIUM_FALCIPARUM ------------aRKYfVaaNWKcNGtleSIksLtnsfNn--ldf
1VGAB_Plasmodium_falciparum -------------RKYfVaaNWKcNGtleSIksLtnsfNn--ldf
Plasmodium_berghei ------------aRKYfVsaNWKcNGtEySIksLadsfNt--vdf
Plasmodium_chabaudi ------------aRKYfVsaNWKcNGtKdSIktLadsfNt--vdf
===============================================================================
B E_COLI -------------RhplVmGNWKLNGSRhmVhELVsnLrk--ela
B VIBRIO_MARINUS -------------RhpvVmGNWKLNGSKemVvDLLngLNa--ele
B Actinobacillus_pleuropneumoniae -----------a-RRplVmGNWKLNGSKaftkELIagLka--ela
B Actinobacillus_succinogenes ----------as-RKplVmGNWKLNGSKaftrELIegLkt--ela
B Erwinia_carotovora -------------RhplVmGNWKLNGStnlVnELIagLrk--els
B Haemophilus_ducreyi -----------a-RRplVmGNWKLNGSKaftqQLIaeLkt--ela
B Haemophilus_influenzae -----------a-RRplVmGNWKLNGSKaftkELIegLka--elh
B Histophilus_somni -----------a-RRplVmGNWKLNGSKaftkELItgLkd--eln
B Mannheimia_succiniciproducens -----------a-RRplVmGNWKLNGSKaftkELIegLka--ela
B Pasteurella_multocida -----------a-RRplVmGNWKLNGSKaftkaLIedLkt--ela
B Photobacterium_profundum -------iwrktmRhpvVmGNWKLNGSKemVvnLLngLNa--ele
B Photorhabdus_luminescens -------------RhplVmGNWKLNGSthmVnELItgLrq--els
B Vibrio_cholerae -------------RRpvVmGNWKLNGSKamVtDLLngLNa--ele
B Vibrio_fischeri -------------RhpvVmGNWKLNGSKemVvELLngLNa--ele
B Vibrio_parahaemolyticus -------------RRpvVmGNWKLNGSKamVtELLtgLNa--ele
B Vibrio_vulnificus -------------RRpvVmGNWKLNGSKtmVaELLtgLNa--ele
B Yersinia_pestis -------------RhplVmGNWKLNGSthmVnELIagLrk--els
B Salmonella_typhi-TPIS -------------RhplVmGNWKLNGSRhmVnELVanLrk--elt
B Salmonella_typhi-TPIS_SALTY -------------RhplVmGNWKLNGSRhmVnELVanLrk--elt
===============================================================================
B THERMUS_AQUATICUS -------------RRvlVaGNWKMHktpsearvwfaeLkr---ll
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS -------------RKpiIaGNWKMHktlaeavQfVedVkg--hvp
B Bacillus_clausii -------------RKpiIaGNWKMNktigeavDfVeaVka--nvp
B Bacillus_halodurans -------------RKpiIaGNWKMNktvgeakafVeeVkg--aip
B Bacillus_licheniformis -------------RKpiIaGNWKMNkvlseavsfVeeVks--sip
B Bacillus_megaterium -------------RKpiIaGNWKMNkvlseatsfVeeVkg--avp
B Bacillus_subtilis -------------RKpiIaGNWKMNktlgeavsfVeeVks--sip
B Listeria_monocytogenes-TPIS1 -------------RKpiIaGNWKMNktaakagQfaedVkn--nvp
B Listeria_monocytogenes-TPIS1_LI -------------RKpiIaGNWKMNktaakagQfaedVkn--nvp
===============================================================================
Consensus xxxxxxxxxxxxxRQfxVxGNWKMNgnKxnLxELIxxLNxxxxxx
140 150 160 170 180
----|----:----|----:----|----:----|----:----|
Consensus xxxxxEVVVaPPxIYLNxAKxxxxLxxxxxxxxxxxxxxxxxxxE
===============================================================================
* S_CEREVISIAE ipenvEVVIcPPatYLDysvs--lV--k--k---p---------Q
* Candida_albicans lpkdvEVVIcPPaLYLglAve--qn--k--q---p---------t
* Candida_glabrata lpenvEVVIcPPatYLDytvs--lV--s--k---k---------Q
* Debaryomyces_hansenii lpsnvEVVIAPPapYIalAvn--en--k--q---k---------t
* Eremothecium_gossypii ladnvEVVIcPPatYLDhAvs--lV--s--h---p---------Q
* Yarrowia_lipolytica ldpktEVVIsPPfpYLllAKe--sL--k--k---p---------t
* Zygosaccharomyces_bailii ldpkvEVVLcPPapYLDytvs--lV--k--k---s---------Q
* Kluyveromyces_lactis-TPIS ipsnvEVVIAPPaIYLDhAva--ln--k--r---k---------E
* Kluyveromyces_lactis-TPIS_KLUMA ipsnvEVVIAPPaaYLDhAvs--ln--k--k---a---------Q
===============================================================================
* C_ELEGANS dnssvDVVVAPPapYLayAKs--kL--k--a-------------g
* HUMAN vpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
* RABBIT vpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
* CHICKEN lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1SPQA_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1SPQB_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1SQ7A_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1SSDA_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1SU5A_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1SW3A_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1SW7A_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1TPB1_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1TPC1_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1TPUA_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1TPVA_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* 1TPWA_Chicken lsadtEVVcgaPsIYLDfARq--kL--d--a-------------K
* Acipenser_brevirostrum inadtDVVcgaPtIYLDfvRs--kL--d--s-------------K
* Anopheles_gambiae ldpntEVVVgcPapYLSlARs--lL--p--e-------------t
* Bovine vpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
* C_briggsae dnsnvDVVVAPPapYLayAKa--nL--k--a-------------g
* Canis_lupus vpadtEVVcAPPtaYIDfARq--kL--d--a-------------K
* Danio_rerio lnpdtEVVcgaPtIYLDyARs--kL--n--p-------------n
* Gorilla_gorilla vpadtKVVcAPPtaYIDfARq--kL--d--p-------------K
* Latimeria_chalumnae vpftgEIVcAPPeaYLDfARl--kV--d--p-------------K
* Lepisosteus_osseus lnpdtEVVcgaPsIYLDfARq--kL--d--a-------------K
* Macaca_mulatta vpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
* Mouse vpagtEVVcAPPtaYIDfARq--kL--d--p-------------K
* Oryzias_latipes lhedtEVVcAaPsIYLDfARs--gL--d--s-------------r
* Pongo_pygmaeus vpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
* Schistosoma_mansoni fddntEVLIAPPsVFLHeiRk--sL--k--k-------------E
* Strongylocentrotus_purpuratus ipgntDVVVAPPtVYLDymns--kI--p--a-------------g
* Pig lpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
* Tribolium_castaneum lspntEVIVgvPaIYLehvRt--nL--p--q-------------s
* X_laevis mnadtEVVcgaPaIYLDfARq--kL--d--a-------------K
* D_melanogaster-TPIS ldpntEVVIgcPaIYLmyARn--lL--p--c-------------E
* D_melanogaster-TPIS_VAR ldpntEVVIgcPaIYLmyARn--lL--p--c-------------E
* Rat-Q6P793 lpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
* Rat-TPIS lpadtEVVcAPPtaYIDfARq--kL--d--p-------------K
===============================================================================
ENTAMOEBA_HISTOLYTICA lakkvEVIVgvPfIYIpkvQq--iLageang---a---------n
===============================================================================
LEISHMANIA_MEXICANA ishdvQcVVAPtfVhIplvQa--kL--r--n---p---------K
TRYPANOSOMA_CRUZI fdhdvQcVVAPtfLhIpmtKa--rL--t--n---p---------K
TRYPANOSOMA_BRUCEI inhdvQcVVAstfVhLamtKe--rL--s--h---p---------K
1KV5A_Trypanosoma_brucei inhdvQcVVAstfVhLamtKe--rL--s--h---p---------K
1MSSA_Trypanosoma_brucei inhdvQcVVAstsshLamtKe--rL--s--h---p---------K
1TRI0_Trypanosoma_brucei inhdvQcVVAstfVhLamtKe--rL--s--h---p---------K
1TTI0_Trypanosoma_brucei inhdvQcVVAstfVhLamtKe--rL--s--h---p---------K
1TTJ0_Trypanosoma_brucei inhdvQcVVAstsshLamtKe--rL--s--h---p---------K
Leishmania_donovani ishdvQcVVAPtfVhIplvQa--kL--r--n---p---------K
Leishmania_tropica ishdvQcVVAPtfVhIplvQa--kL--r--n---p---------K
===============================================================================
PLASMODIUM_FALCIPARUM dpsklDVVVfPvsVhyDhtRk--lL--q--s-------------K
1VGAB_Plasmodium_falciparum dpsklDVVVfPvsVhyDhtRk--lL--q--s-------------K
Plasmodium_berghei dpsklDVVVfPvsVhyDltRk--lL--n--k-------------K
Plasmodium_chabaudi dpsklDVVVfPvsVhyDlARn--lL--n--k-------------K
===============================================================================
B E_COLI gvagcaVaIAPPeMYIDmAKr--ea--e------g--------sh
B VIBRIO_MARINUS gvtgvDVaVAPPaLFVDlAEr--tL--te-a---g--------sa
B Actinobacillus_pleuropneumoniae dvkgcDVaIAPPvMYLaeAEa--aL--a------g-------qsv
B Actinobacillus_succinogenes gvegcDVaIAPPvMYLaeAEt--aL--a------d--------sK
B Erwinia_carotovora tvdgcgVaIAPPaIYLDqAnh--qL--a------g--------sr
B Haemophilus_ducreyi eitgcDVaIAPPvMYLSeAEi--aL--a------g-------qst
B Haemophilus_influenzae dvtgcDVaIAPPvMYLgtAEa--aL--s------gcgcscggksv
B Histophilus_somni avsgcDVaIAPPvMYLaeAEt--aL--v------s--------sD
B Mannheimia_succiniciproducens gvegcDVaIAPPvMYLaeAEa--aL--a------g--------sK
B Pasteurella_multocida gvegcDVaIAPPvMYLaeAEa--aL--kcscscgg--------ka
B Photobacterium_profundum gvtgvDVaVAPPaLFIDlAEhtlte--a------g--------sa
B Photorhabdus_luminescens svtgcDVaIAPPaLYLSqAKq--aL--a------g--------sr
B Vibrio_cholerae gvegvDVVVAPPaMYLDlAErlike--g------g--------nK
B Vibrio_fischeri gvtgvDVaVAPPaLFVDlAErtlte--a------g--------sa
B Vibrio_parahaemolyticus gvegvDVaVAPPaLYIDlAErliae--g------g--------nK
B Vibrio_vulnificus gvegvDVaVAPPaLYIDlAErliae--g------g--------nK
B Yersinia_pestis tvdgcgVaIAPPaIYLNqAKh--eL--a------g--------sr
B Salmonella_typhi-TPIS gvagcDVaIAPPeMYIDlAKr--aa--a------g--------sh
B Salmonella_typhi-TPIS_SALTY gvagcDVaIAPPeMYIDlAKr--aa--a------g--------sh
===============================================================================
B THERMUS_AQUATICUS pplqsEaaVlPafpiLpvAKe--vLa-e--t-------------Q
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS padevisVVcaPfLFLDrlvq--aad-g--t-------------D
B Bacillus_clausii aqatvDsVVcaPaLFLDrllq--aVk-g--t-------------E
B Bacillus_halodurans ssdkvDsVVcsPaLFLeglvq--kae-g--t-------------E
B Bacillus_licheniformis aadkaEaVVcaPaLFLeklts--aVk-g--t-------------D
B Bacillus_megaterium spesvDsVVcaPaLFLDrlve--atk-g--t-------------D
B Bacillus_subtilis aadkaEaVVcaPaLFLeklas--aVk-g--t-------------D
B Listeria_monocytogenes-TPIS1 ssdavEsVVAaPaLFLqelvr--lte-g--t-------------D
B Listeria_monocytogenes-TPIS1_LI ssdavEsVVAaPaLFLqelvr--lte-g--t-------------n
===============================================================================
Consensus xxxxxEVVVaPPxIYLNxAKxxxxLxxxxxxxxxxxxxxxxxxxE
190 200 210 220
----:----|----:----|----:----|----:----|----:
Consensus IxVxAQNxxxxxnGAFTGEISpxMIKDiGaxYVILGHSERRxxYx
===============================================================================
* S_CEREVISIAE VtVgAQNaylkaSGAFTGEnSvdqIKDVGAkWVILGHSERRsyFh
* Candida_albicans VaIgAQNvfdkscGAFTGEtcasqIlDVGAsWtLtGHSERRtiik
* Candida_glabrata VtVggQNtytkaSGAYTGEnSvdqLKDVGAkWVILGHSERRtyFh
* Debaryomyces_hansenii IeVsAQNcfdkaSGAYTGEISPeqIKDLGAtWtLtGHSERRtiik
* Eremothecium_gossypii VtVgAQNaytkaSGAYTGEnSvdqIKDVGAkWVILGHSERRtyFn
* Yarrowia_lipolytica VsVagQNsfdkgDGAFTGEVSvaqLKDVGAkWVILGHSERRtink
* Zygosaccharomyces_bailii VsVgAQNaylkaSGAFTGEnSvdqIKDVGAkWVILGHSERRqyFr
* Kluyveromyces_lactis-TPIS VkIsAQNayskaSGAYTGEnSveqIKDVGAeWVILGHSERRtyFn
* Kluyveromyces_lactis-TPIS_KLUMA VsVaAQNaylkaSGAFTGEnSveqIKDVGAeWVILGHSERRtyFh
===============================================================================
* C_ELEGANS VlVaAQNcykvpkGAFTGEISPaMIKDLGleWVILGHSERRhvFg
* HUMAN IaVaAQNcykvtNGAFTGEISPgMIKDcGAtWVVLGHSERRhvFg
* RABBIT IaVaAQNcykvtNGAFTGEISPgMIKDcGAtWVVLGHSERRhvFg
* CHICKEN IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1SPQA_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1SPQB_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1SQ7A_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1SSDA_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1SU5A_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1SW3A_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1SW7A_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1TPB1_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHSERRhvFg
* 1TPC1_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHpERRhvFg
* 1TPUA_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGNSERRhvFg
* 1TPVA_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGNpERRhvFg
* 1TPWA_Chicken IgVaAQNcykvpkGAFTGEISPaMIKDIGAaWVILGHpERRhvFg
* Acipenser_brevirostrum MgVaAQNcykvakGAFTGEVSPaMIKDcGvsWVILGHSERRhvFg
* Anopheles_gambiae IgVaAQNcykvakGAFTGEISPaMLKDLGlgWVILGHSERRaiFg
* Bovine IaVaAQNcykvaNGAFTGEISPgMIKDLGAtWVVLGHSERRhvFg
* C_briggsae VlVaAQNcyktakGAFTGEISPaMIKDLGleWVILGHSERRhvFg
* Canis_lupus IaVaAQNcykvtNGAFTGEISPgMIKDcGAtWVVLGHSERRhvFg
* Danio_rerio IdVaAQNcykvakGAFTGEISPaMIKDcGvkWVILGHSERRhvFg
* Gorilla_gorilla IaVaAQNcykvtNGAFTGEISPgMIKDcGAtWVVLGHSERRhvFg
* Latimeria_chalumnae fgVaAQNcykvskGAFTGEISPaMIKDcGvtWVILGHSERRhvFg
* Lepisosteus_osseus IaVaAQNcykvakGAFTGEISPaMIKDcGvsWVILGHSERRhvFg
* Macaca_mulatta IaVaAQNcykvtNGAFTGEISPgMIKDcGAtWVVLGHSERRhvFg
* Mouse IaVaAQNcykvtNGAFTGEISPgMIKDLGAtWVVLGHSERRhvFg
* Oryzias_latipes IsVaAQNcykvakGAFTGEISPaMIKDcGAdWVILGHSERRhvFg
* Pongo_pygmaeus IaVaAQNcykvtNGAFTGEISPgMIKDyGAtWVVLGHSERRhvFg
* Schistosoma_mansoni IhVaAQNcykvskGAFTGEISPaMIRDIGcdWVILGHSERRniFg
* Strongylocentrotus_purpuratus VfVaAQNcykvpkGAFTaEtSPaMLQDLGvgWVILGHSERRhvFg
* Pig IaVaAQNcykvaNGAFTGEIgPgMIKDLGAtWVVLGHSERRhvFg
* Tribolium_castaneum IeVaAQNcykvpkGAFTGEISPaMIKDIGvnWVILGHSERRqiFg
* X_laevis IaLsAQNcykvakGAFTGEISPaMIKDcGAtWVILGHSERRhvFg
* D_melanogaster-TPIS LgLagQNaykvakGAFTGEISPaMLKDIGAdWVILGHSERRaiFg
* D_melanogaster-TPIS_VAR LgLagQNaykvakGAFTGEISPaMLKDIGAdWVILGHSERRaiFg
* Rat-Q6P793 IaVaAQNcykvtNGAFTGEISPgMIKDLGAtWVVLGHSERRhiFg
* Rat-TPIS IaVaAQNcykvtNGAFTGEISPgMIKDLGAtWVVLGHSERRhiFg
===============================================================================
ENTAMOEBA_HISTOLYTICA IlVsAENawtk-SGAYTGEVhvgMLvDcqvpYVILGHSERRqiFh
===============================================================================
LEISHMANIA_MEXICANA yvIsAENaiak-SGAFTGEVSmpILKDIGvhWVILGHSERRtyYg
TRYPANOSOMA_CRUZI fqIaAQNaitr-SGAFTGEVSlqILKDyGisWVVLGHSERRlyYg
TRYPANOSOMA_BRUCEI fvIaAQNaiak-SGAFTGEVSlpILKDfGvnWIVLGHSERRayYg
1KV5A_Trypanosoma_brucei fvIaAQNaiak-SGAFTGEVSlpILKDfGvnWIVLGHSERRayYg
1MSSA_Trypanosoma_brucei fvIaAQNagna-D-------alasLKDfGvnWIVLGHSERRayYg
1TRI0_Trypanosoma_brucei fvIaAQNagna-D-------alasLKDfGvnWIVLGHSERRayYg
1TTI0_Trypanosoma_brucei fvIaAQNagna-D-------glasLKDfGvnWIVLGHSERRwyYg
1TTJ0_Trypanosoma_brucei fvIaAQNagna-D-------alasLKDfGvnWIVLGHSERRayYg
Leishmania_donovani yaVsAENaiak-SGAFTGEVSmpILKDLGinWVILGHSERRtyYg
Leishmania_tropica yvVsAENaiak-SGAFTGEVSmpILKDLGinWVILGHSERRtyYg
===============================================================================
PLASMODIUM_FALCIPARUM fstgiQNvskfgNGsYTGEVSaeIaKDLnieYVIIGHfERRkyFh
1VGAB_Plasmodium_falciparum fstgiQNvskfgNGsYTGEVSaeIaKDLnieYVIIGHfERRkyFh
Plasmodium_berghei IgtgiQNvskfgNGsYTGEVSaeIaKNLnieYVLIGHfERRkyFh
Plasmodium_chabaudi IgtgiQNvskfgNGsYTGEVSaeIaKNLdieYVLIGHfERRkyFh
===============================================================================
B E_COLI ImLgAQNvdlnlSGAFTGEtSaaMLKDIGAqYIIIGHSERRtyhk
B VIBRIO_MARINUS IiLgAQNtdlnnSGAFTGDMSPaMLKEfGAthIIIGHSERReyha
B Actinobacillus_pleuropneumoniae IaLgAQNvdvnvqGAFTGDISteMLKDfGAkYIIIGHSERRtyhk
B Actinobacillus_succinogenes IaLgsQNvdvnvkGAFTGDISteMLKDfGAkYIIIGHSERRtyhk
B Erwinia_carotovora IaLgAQNvdvnlSGAFTGEtSaeMLKDIGAkYIIIGHSERRtyhk
B Haemophilus_ducreyi IrLgAQNvdintqGAFTGDIStaMLQEfcAkYIIIGHSERRtyha
B Haemophilus_influenzae IqLgAQNvdinvkGAFTGDISteMLKDfGAkYIIIGHSERRtyhk
B Histophilus_somni IaLgtQNvdlnkqGAFTGDISteMLKDfGvkYVIIGHSERRqyhh
B Mannheimia_succiniciproducens IvLgsQNvdvnvkGAFTGDISteMLKDfGAkYIIIGHSERRtyhk
B Pasteurella_multocida IaLgAQNvdvnvqGAFTGDISteMLKDfGAkYIIIGHSERRtyhk
B Photobacterium_profundum IiLgAQNsdlnnSGAFTGDMSPaMLKEfGAshIIIGHSERReyhn
B Photorhabdus_luminescens IaLgAQDvdvnlSGAFTGEtSatMLKDIGAeYIIIGHSERRtyhq
B Vibrio_cholerae LiLgAQNtdthnSGAYTGDMSPaMLKDfGAshIIIGHSERRdyhk
B Vibrio_fischeri IiLgAQNtdlnnSGAFTGDMSPaMLKEfGAthIIIGHSERReyhn
B Vibrio_parahaemolyticus IiLgAQNtdlnnSGAFTGDMSPeMLKDfGAthIIIGHSERReyhn
B Vibrio_vulnificus IiLgAQNtdinnSGAFTGDMSPaMLKDfGAthIIIGHSERReyhn
B Yersinia_pestis IaLgAQNvdvnlSGAFTGEtSaeMLKDIGAqYIIIGHSERRtyhq
B Salmonella_typhi-TPIS ImLgAQNvdlnlSGAFTGEtSaeMLKDIGAqYIIIGHSERRtyhk
B Salmonella_typhi-TPIS_SALTY ImLgAQNvdlnlSGAFTGEtSaeMLKDIGAqYIIIGHSERRtyhk
===============================================================================
B THERMUS_AQUATICUS VgygAQDvsahkeGAYTGEVSarMLsDLGcrYaIVGHSERRryhg
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS LkIgAQtmhfadqGAYTGEVSPvMLKDLGvtYVILGHSERRqmFa
B Bacillus_clausii LkIgAQtmhfedNGAFTGEISPkaLsDMGvhYVIIGHSERRemFa
B Bacillus_halodurans LrIgAQNmhfeeSGAFTGEISPvaLsDMkvdYVILGHSERRdmFa
B Bacillus_licheniformis LkVgAQNmhfeeSGAFTGEISPaaLKDLGveYcVIGHSERRemFa
B Bacillus_megaterium LkIgAQNmhfeeNGAFTGEVSPvaLaDLGvnYVILGHSERRemFa
B Bacillus_subtilis LkVgAQNmhfeeSGAFTGEISPvaLKDLGvdYcVIGHSERRemFa
B Listeria_monocytogenes-TPIS1 LrVsAQNcyfedeGAFTGEISPfaLaDLGvsYVIIGHSERReyFh
B Listeria_monocytogenes-TPIS1_LI LrVaAQNcyfedeGAFTGEISPfaLaDLGvsYVIIGHSERReyFh
===============================================================================
Consensus IxVxAQNxxxxxnGAFTGEISpxMIKDiGaxYVILGHSERRxxYx
230 240 250 260 270
----|----:----|----:----|----:----|----:----|
Consensus ESNElIaEKxxxAlexGLxvIlCIGESLEEREAGqTeEVVxKQIE
===============================================================================
* S_CEREVISIAE EdDKfIADKtkfALgqGVgVILCIGETLEEKKAGKTlDVVeRQLn
* Candida_albicans ESDEfIAEKtkfALDtGVkVILCIGETLEERKgGvTlDVcaRQLD
* Candida_glabrata EdDKIVAEKtkfALDqGLgVILCIGETLEEKKAGvTlKVVeRQLD
* Debaryomyces_hansenii ESDDfIAsKtkfALDqGLsVILCIGETLEERKAnvTlDVcaRQLD
* Eremothecium_gossypii EdDEqVAEKtafALErGVsVILCIGETLDEKKAGvTlDVVkRQLt
* Yarrowia_lipolytica ESSEwIADKtkyALDnGLdVILCIGETIDEKKAGKTlDVVrsQLD
* Zygosaccharomyces_bailii EdDQLIAEKtafALsqGVgVILCIGETLDQKKAGtTlQVVeRQLQ
* Kluyveromyces_lactis-TPIS ETDEIVAEKtkfALDsGVkVILCIGETLEEKQqniTlQVVqRQLQ
* Kluyveromyces_lactis-TPIS_KLUMA ETDEfIADKtkfALDsGVkVILCIGETLEEKQkGiTlEVVqRQLQ
===============================================================================
* C_ELEGANS ESDaLIAEKtvhALEaGIkVVfCIGEkLEEREAGhTKDVnfRQLQ
* HUMAN ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* RABBIT ESDELIgQKvahALseGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* CHICKEN ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1SPQA_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1SPQB_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1SQ7A_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1SSDA_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1SU5A_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1SW3A_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1SW7A_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1TPB1_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1TPC1_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1TPUA_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1TPVA_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* 1TPWA_Chicken ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Acipenser_brevirostrum ESDELIgQKvahALQeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Anopheles_gambiae ETDELIAEKvahALaeGLkVIaCIGETLQEREAGQTEaVcfRQtK
* Bovine ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* C_briggsae ESDaLIAEKtvhALEsGIkVIfCIGEkLEEREAGhTKDVnfRQLQ
* Canis_lupus ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Danio_rerio ESDELIgQKvahALEnGLgVIaCIGEkLDEREAGiTEKVVfaQtK
* Gorilla_gorilla ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Latimeria_chalumnae ESDELIgQKvshALseGLgVVaCIGEkLDEREAGiTEgVVfEvtE
* Lepisosteus_osseus ESDELIgQKvahALEgGLgVIaCIGEkLDEREAGiTDKVVfaQtK
* Macaca_mulatta ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Mouse ESDELIgQKvshALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Oryzias_latipes ENDELIgQKvahALEsdLsVIaCIGEkLEEREAGtTEDVIfaQtQ
* Pongo_pygmaeus ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Schistosoma_mansoni ESDELIAEKvqhALaeGLsVIaCIGETLsEREsnKTEEVcvRQLK
* Strongylocentrotus_purpuratus ESDELIAQKvahALsckLkVVaCIGEkLDEREkGQTnEVVyRQMr
* Pig ESDELIgQKvahALaeGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Tribolium_castaneum ETDELIAEKvahALEaGLkVIaCIGETLEEREgGKTEEVVfRQtK
* X_laevis EcDELIgQKvahALseGIgVIaCIGEkLDQREAGiTEKVVfEQtK
* D_melanogaster-TPIS ESDaLIAEKaehALaeGLkVIaCIGETLEEREAGKTnEVVaRQMc
* D_melanogaster-TPIS_VAR ESDaLIAEKaehALaeGLkVIaCIGETLEEREAGKTnEVVaRQMc
* Rat-Q6P793 ESDELIgQKvnhALseGLgVIaCIGEkLDEREAGiTEKVVfEQtK
* Rat-TPIS ESDELIgQKvnhALseGLeVIaCIGEkLDEREAGiTEKVVfEQtK
===============================================================================
ENTAMOEBA_HISTOLYTICA ESNEqVAEKvkvAIDaGLkVIaCIGETeaQRiAnQTEEVVaaQLK
===============================================================================
LEISHMANIA_MEXICANA ETDEIVAQKvseAcKqGfmVIaCIGETLQQREAnQTaKVVlsQts
TRYPANOSOMA_CRUZI ETNEIVAEKvaqAcaaGfhVIVCVGETnEEREAGRTaaVVltQLa
TRYPANOSOMA_BRUCEI ETNEIVADKvaaAVasGfmVIaCIGETLQEREsGRTavVVltQIa
1KV5A_Trypanosoma_brucei ETNEIVADKvaaAVasGfmVIaCIGETLQEREsGRTavVVltQIa
1MSSA_Trypanosoma_brucei ETNEIVADKvaaAVasGfmVIaCIGETLQEREsGRTavVVltQIa
1TRI0_Trypanosoma_brucei ETNEIVADKvaaAVasGfmVIaCIGETLQEREsGRTavVVltQIa
1TTI0_Trypanosoma_brucei ETNEIVADKvaaAVasGfmVIaCIGETLQEREsGRTavVVltQIa
1TTJ0_Trypanosoma_brucei ETNEIVADKvaaAVasGfmVIaCIGETLQEREsGRTavVVltQIa
Leishmania_donovani ETDEIVAQKvadAcKqGfmVIaCIGETLQQREAnQTaKVVlsQts
Leishmania_tropica ETDEtVAQKvadAcKqGfmVIaCIGETLQQREAnQTaKVVlsQts
===============================================================================
PLASMODIUM_FALCIPARUM ETDEdVrEKlqasLKnnLkaVVCfGESLEQREqnKTiEVItKQVK
1VGAB_Plasmodium_falciparum ETDEdVrEKlqasLKnnLkaVVCfGESLEQREqnKTiEVItKQVK
Plasmodium_berghei ETDEdVrQKlqqAIKnnLkaVVCfGESLEQREsnKTiDVItKQVK
Plasmodium_chabaudi ETDEdVrEKlqqAIKhnLkaVVCfGESLEQREsnKTiEVItKQVK
===============================================================================
B E_COLI ESDELIAKKfavlkEqGLtpVLCIGETeaEnEAGKTEEVcaRQID
B VIBRIO_MARINUS ESDEfVAKKfaflkEnGLtpVLCIGESdaQnEAGETmaVcaRQLD
B Actinobacillus_pleuropneumoniae EcDtfIAKKfaalkaaGLvpVLCIGETeaEnEAGQTEaVcaKQID
B Actinobacillus_succinogenes ESDEfIAKKfsalkEaGLtpVLCIGETeEEnEAGKTEEVVsRQID
B Erwinia_carotovora ESDEfIAKKfgvlkDaGLipVLCIGETeaEnEAGQTEaVcaRQLD
B Haemophilus_ducreyi ESDQfIAKKfaalktaGLtpVLCIGETeaEnEAGQTQQVcaRQID
B Haemophilus_influenzae ESDEfVAKKfgalkEaGLvpVLCIGESeaEnEAGKTEEVcaRQID
B Histophilus_somni ESDEfIAKKfgvlkDaGLvpVLCIGESeaEnEAGKTEEVcaRQID
B Mannheimia_succiniciproducens ESDEfVAQKfgalkEaGLtpVLCIGESeaEnEAGKTEEVcaRQID
B Pasteurella_multocida ESDEfIAKKfaalkQaGLvpVLCIGESeaEnEAGKTEEVcaRQID
B Photobacterium_profundum ESDEfVAKKfaflkEnGLtpVLCIGESdaQnEAGETmaVcaRQLD
B Photorhabdus_luminescens ESDEfIAKKfailkQqGLipVLCIGETeQEnEAGQTEsVcaRQID
B Vibrio_cholerae ESDEfVAKKfaflkEnGLtpVfCIGETeaQnEAGETEaVcaRQIn
B Vibrio_fischeri ESDEfVAKKfaflkEnGLtpVLCIGESeaQnEAGETvaVcaRQID
B Vibrio_parahaemolyticus ESDEfIAKKfnflkEnGLtpVfCIGESeaQnEAGETEaVcaRQIn
B Vibrio_vulnificus ESDEfVAKKfaflkEnGLkpVfCIGETeaQnEAGETEaVcaRQIn
B Yersinia_pestis ESDELIAKKfgvlkEiGLipVLCIGESeaEnEAGQTEaVcaKQLD
B Salmonella_typhi-TPIS ESDELIAKKfavlkEqGLtpVLCIGETeaEnEAGKTEEVcaRQID
B Salmonella_typhi-TPIS_SALTY ESDELIAKKfavlkEqGLtpVLCIGETeaEnEAGKTEEVcaRQID
===============================================================================
B THERMUS_AQUATICUS ETDaLVAEKakrlLEeGItpILCVGEpLEvREkGEavpytlRQLr
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS ETDEtVnKKvlaAftrGLipIICcGESLEEREAGQTnaVVasQVE
B Bacillus_clausii ETDEtVnKKvhaAfahhLvpIMCcGETaEEREAGKmEaVVkEQVE
B Bacillus_halodurans ETDELVnKKthaAfahGLtpIVCVGETLEEREAnQTyDVVktQVE
B Bacillus_licheniformis ETDEtVnKKahaAfKyGIvpIICVGETLEEREAnKTnELVadQVK
B Bacillus_megaterium ETDEtVnQKtiaAfKhGLtpIVCcGETnEEyEqdQTKtVVanQVQ
B Bacillus_subtilis ETDEtVnKKahaAfKhGIvpIICVGETLEEREAGKTnDLVadQVK
B Listeria_monocytogenes-TPIS1 ETDEdInKKahaifKhGMtpIICcGETLDQREAGQTDtwVrgQIr
B Listeria_monocytogenes-TPIS1_LI ETDEdInKKahaifKhGMtpIICcGETLDQREAGQTDtwVrgQIr
===============================================================================
Consensus ESNElIaEKxxxAlexGLxvIlCIGESLEEREAGqTeEVVxKQIE
280 290 300 310
----:----|----:----|----:----|----:----|----:
Consensus AIlnxxxvexxxeFsxvVLAYEPVWaigtgksaTPEQAQEVHxxL
===============================================================================
* S_CEREVISIAE AVLee--VK---DWTnVVVAYEPVWAIGTGlaATPEdAQDIHasI
* Candida_albicans AVski--Vs---DWSnIVVAYEPVWAIGTGlaATPEdAEEtHkgI
* Candida_glabrata AVIae--VK---DWTnVVIAYEPVWAIGTGlaATaEdAQDIHhsI
* Debaryomyces_hansenii AVarv--Vs---DWSkIVVAYEPVWAIGTGlaATPEdAQEtHkaI
* Eremothecium_gossypii pVLek--VK---DWTnVVIAYEPVWAIGTGlaATaEdAQDIHaaI
* Yarrowia_lipolytica pVIak--IK---DWSnVVIAYEPVWAIGTGlaATaEdAQQIHheI
* Zygosaccharomyces_bailii AVIDk--VK---DWSnVVIAYEPVWAIGTGlaATPEdAQEIHhsI
* Kluyveromyces_lactis-TPIS AVLek--VQ---DWTnVVVAYEPVWAIGTGlaATaEdAQDIHhsI
* Kluyveromyces_lactis-TPIS_KLUMA AVLDk--VQ---DWTnVVVAYEPVWAIGTGlaATsDdAQaIHhsI
===============================================================================
* C_ELEGANS AIVDk--gv---sWenIVIAYEPVWAIGTGKTASgEQAQEVHewI
* HUMAN vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* RABBIT vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* CHICKEN AIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* 1SPQA_Chicken AIaDn--VK---DWSkVVLAYEPVWAIxxGKTkTPQQAQEVHekL
* 1SPQB_Chicken AIaDn--VK---DWSkVVLAYEPVWxxxxxxxxTPQQAQEVHekL
* 1SQ7A_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGlwATPQQAQEVHekL
* 1SSDA_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGySlTPQQAQEVHekL
* 1SU5A_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGnpnTPQQAQEVHekL
* 1SW3A_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGKvATPQQAQEVHekL
* 1SW7A_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGnSsTPQQAQEVHekL
* 1TPB1_Chicken AIaDn--VK---DWSkVVLAYDPVWAIGTGKTATPQQAQEVHekL
* 1TPC1_Chicken AIaDn--VK---DWSkVVLAYDPVWAIGTGKTATPQQAQEVHekL
* 1TPUA_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* 1TPVA_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* 1TPWA_Chicken AIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Acipenser_brevirostrum AIaDn--VK---DWSkVVLAYEPVWAIGTGKTASPQQAQEVHekL
* Anopheles_gambiae AIaaq--VK---DWSnVVIAYEPVWAIGTGKTATPEQAQEVHaaL
* Bovine vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* C_briggsae AIVDk--gv---sWenIVIAYEPVWAIGTGKTASPEQAQEVHewI
* Canis_lupus vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Danio_rerio fIaDn--VK---DWSkVVLAYEPVWAIGTGKTASPQQAQEVHdkL
* Gorilla_gorilla vItDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Latimeria_chalumnae vIaDd--VK---DWSkVVLAYEPVWAIGTGKTASPQQsQELHgkL
* Lepisosteus_osseus vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHdkL
* Macaca_mulatta vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Mouse vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Oryzias_latipes vIaen--Vm---DWekVVLAYEPVWAIGTGKTATPEQAQEVHekL
* Pongo_pygmaeus vIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Schistosoma_mansoni AIaNk--IKsadEWkrVVVAYEPVWAIGTGKvATPQQAQEVHnfL
* Strongylocentrotus_purpuratus ALaDv--It---DWgnVVIAYEPVWAIGTGKTATPQQAQEVHqnL
* Pig vIaDn--VK---DWNkVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Tribolium_castaneum AIagk--IK---DWSnVVIAYEPVWAIGTGKTATPQQAQEVHkaL
* X_laevis AIaDn--VK---DWSkVVLAYEPVWAIGTGKTATPEQAQEVHkkL
* D_melanogaster-TPIS Ayaqk--IK---DWknVVVAYEPVWAIGTGQTATPDQAQEVHafL
* D_melanogaster-TPIS_VAR Ayaqk--IK---DWknVVVAYEPVWAIGTGKTATPDQAQEVHafL
* Rat-Q6P793 AIaDn--VK---DWckVVLAYEPVWAIGTGKTATPQQAQEVHekL
* Rat-TPIS AIaDn--VK---DWckVVLAYEPVWAIGTGKTATPQQAQEVHekL
===============================================================================
ENTAMOEBA_HISTOLYTICA AInNa--Iske-aWknIILAYEPVWAIGTGKTATPDQAQEVHqyI
===============================================================================
LEISHMANIA_MEXICANA AIaak--Ltkd-aWNqVVLAYEPVWAIGTGKvATPEQAQEVHllL
TRYPANOSOMA_CRUZI AVaqk--Lske-aWSrVVIAYEPVWAIGTGKvATPQQAQEVHelL
TRYPANOSOMA_BRUCEI AIakk--LKka-DWakVVIAYEPVWAIGTGKvATPQQAQEaHalI
1KV5A_Trypanosoma_brucei AIakk--LKka-DWakVVIAYEPVWAIGTGKvATPQQAQEaHalI
1MSSA_Trypanosoma_brucei AIakk--LKka-DWakVVIAYEPVWAIGTGKvATPQQAQEaHalI
1TRI0_Trypanosoma_brucei AIakk--LKka-DWakVVIAYEPVWAIGTGKvATPQQAQEaHalI
1TTI0_Trypanosoma_brucei AIakk--LKka-DWakVVIAYEPVWAIGTGKvATPQQAQEaHalI
1TTJ0_Trypanosoma_brucei AIakk--LKka-DWakVVIAYEPVWAIGTGKvATPQQAQEaHalI
Leishmania_donovani AIatk--Lpte-aWdqIVLAYEPVWAIGTGKvATPEQAQEVHalL
Leishmania_tropica AIatk--Lpke-aWdqIVLAYEPVWAIGTGKvATPEQAQEVHalL
===============================================================================
PLASMODIUM_FALCIPARUM AfVDl--ID---nFdnVILvYEPLWAIGTGKTATPEQAQlVHkeI
1VGAB_Plasmodium_falciparum AfVDl--ID---nFdnVILvYEPLFAIGTGKTATPEQAQlVHkeI
Plasmodium_berghei AfVDl--IE---nFdnVILAYEPIWAIGTGKTATPEQAQEVHkeI
Plasmodium_chabaudi AfVDl--IE---nFdnVILAYEPIWAIGTGKTATPEQAQEVHkeI
===============================================================================
B E_COLI AVLkt--qgaa-aFegaVIAYEPVWAIGTGKSATPaQAQaVHkfI
B VIBRIO_MARINUS AVINt--qgve-alegaIIAYEPIWAIGTGKaATaEdAQrIHaqI
B Actinobacillus_pleuropneumoniae AVIDa--Lgve-aFNgaVIAYEPIWAIGTGKSATPaQAQaVHafI
B Actinobacillus_succinogenes AVINa--Lgve-aFNgaVIAYEPIWAIGTGKSATPaQAQaVHafI
B Erwinia_carotovora AVLNt--Lgak-aFentVVAYEPVWAIGTGKSATPaQAQaVHkfI
B Haemophilus_ducreyi AIINs--Lgve-aFNqaVIAYEPIWAIGTGKSATPaQAQaVHafI
B Haemophilus_influenzae AVINa--Lgve-aFNgaVIAYEPIWAIGTGKSATPaQAQaVHafI
B Histophilus_somni AVMNt--Lgve-aFNgaVIAYEPIWAIGTGKSATPaQAQaVHafI
B Mannheimia_succiniciproducens AVINa--Lgve-aFNgaVIAYEPIWAIGTGKSATPaQAQaVHafI
B Pasteurella_multocida AVLNt--Lgae-aFNgaVIAYEPIWAIGTGKSATPaQAQaVHafI
B Photobacterium_profundum AVINt--qgve-alegaIIAYEPIWAIGTGKaATaEdAQrIHaqI
B Photorhabdus_luminescens AVLNt--Lgva-aFqgaVIAYEPVWAIGTGKSATPaQAQaVHkfI
B Vibrio_cholerae AVIDa--ygve-alNgaIIAYEPIWAIGTGKaATaDdAQrIHasI
B Vibrio_fischeri AVINt--qgvd-alNgaIIAYEPIWAIGTGKaATaEdAQrIHaqI
B Vibrio_parahaemolyticus AVIDt--ygve-alNgaIIAYEPIWAIGTGKaATaEdAQrIHasI
B Vibrio_vulnificus AVIDa--ygve-alNgaIIAYEPIWAIGTGKaATaEdAQrIHasI
B Yersinia_pestis AVLNt--Lgvk-aFegaVIAYEPIWAIGTGKSATPaQAQaVHkfI
B Salmonella_typhi-TPIS tVLkt--qgaa-aFegaVIAYEPVWAIGTGKSATPaQAQaVHkfI
B Salmonella_typhi-TPIS_SALTY AVLkt--qgaa-aFegaVIAYEPVWAIGTGKSATPaQAQaVHkfI
===============================================================================
B THERMUS_AQUATICUS gsLegvepp---gpeaLVIAYEPVWAIGTGKNATPEdAEaMHqaI
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS kaLagltpE---QvkqaVIAYEPIWAIGTGKSsTPEdAnsVcghI
B Bacillus_clausii ngLaglseE---QvkqtVIAYEPIWAIGTGKSATeKdAnEacayV
B Bacillus_halodurans kgLegltdE---QvkvtVIAYEPVWAIGTGKSsSaEdAnDVcsyI
B Bacillus_licheniformis kaLaglttE---QvaasVIAYEPIWAIGTGKSsTaQdAnEVcahI
B Bacillus_megaterium kaLagltdE---QvkqtVIAYEPIWAIGTGKSsTaEgAnEVcayI
B Bacillus_subtilis kgLaglseE---QvaasVIAYEPIWAIGTGKSsTaKdAnDVcahI
B Listeria_monocytogenes-TPIS1 AaLaglteE---QviksVIAYEPIWAIGTGKSsTsadAnEtcavI
B Listeria_monocytogenes-TPIS1_LI AaLaglteE---QviksVIAYEPIWAIGTGKSsTsadAnEtcavI
===============================================================================
Consensus AIlnxxxvexxxeFsxvVLAYEPVWaigtgksaTPEQAQEVHxxL
320 330 340 350 360
----|----:----|----:----|----:----|----:----|
Consensus RxyLxexiNexIAExLRIiYGGSVSxxNxxELxxQPDVDGfLVGG
===============================================================================
* S_CEREVISIAE RkFLaskLgDkaAseLRILYGGSaNgsNavtfkdKaDVDGFLVGG
* Candida_albicans RahLaKsIgaeqAEktRILYGGSVNgkNakDfkdKaNVDGFLVGG
* Candida_glabrata RsYLaEkLgKdtAEktRILYGGSaNgaNagtfkdKaDVDGFLVGG
* Debaryomyces_hansenii RehLsKsIgadaAEktRILYGGSVNgkNapEfkdKaDVDGFLVGG
* Eremothecium_gossypii RdFLaErtSrdVADaVRILFGGSaNgaNaasfrdKaDVDGFLVGG
* Yarrowia_lipolytica RaYLkDkIgaq-ADkVRIIYGGSVNgkNsgtfkdKsDVDGFLVGG
* Zygosaccharomyces_bailii ReFLaKkLgEktAQetRILYGGSaNgkNavtfkdKPDVDGFLVGG
* Kluyveromyces_lactis-TPIS ReFLaEkLSrdVADsVRILYGGSaNgkNavtfkdKaDVDGFLVGG
* Kluyveromyces_lactis-TPIS_KLUMA ReFLaKkLSKdtAEkIRILYGGSaNgkNavtfkdKaDVDGFLVGG
===============================================================================
* C_ELEGANS RaFLkEkVSpaVADatRIIYGGSVTadNaaELgkKPDIDGFLVGG
* HUMAN RgWLksnVSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGG
* RABBIT RgWLksnVSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGG
* CHICKEN RgWLkthVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1SPQA_Chicken RgWLkshVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1SPQB_Chicken RgWLkshVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1SQ7A_Chicken RgWLkshVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1SSDA_Chicken RgWLkshVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1SU5A_Chicken RgWLkshVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1SW3A_Chicken RgWLkshVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1SW7A_Chicken RgWLkshVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1TPB1_Chicken RgWLkthVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1TPC1_Chicken RgWLkthVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1TPUA_Chicken RgWLkthVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1TPVA_Chicken RgWLkthVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* 1TPWA_Chicken RgWLkthVSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGG
* Acipenser_brevirostrum RqWLkthVSEeVggaVRIIYGGSVTaatckELasKPDVDGFLVGG
* Anopheles_gambiae RkWftEnVSadVsnaIRIqYGGSVTaaNcrELaaKPDIDGFLVGG
* Bovine RgWLksnVSDaVAQsaRIIYGGSVTgatckELasQPDVDGFLVGG
* C_briggsae RaFLkEkVSpaVADatRIIYGGSVTadNaaELgkKPDIDGFLVGG
* Canis_lupus RgWLksnVSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGG
* Danio_rerio RqWLktnVSEaVAnsVRIIYGGSVTggtckELasQkDLDGFLVGG
* Gorilla_gorilla RgWLksnVSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGG
* Latimeria_chalumnae RkWLkEnVSEtVADsVRIIYGGSVTgatckELasEPDVDGFLVGG
* Lepisosteus_osseus RqWLktnVSEaVAsscRIIYGGSVTggtckELasQaDVDGFLVGG
* Macaca_mulatta RgWLksnVSEaVAQstRIIYGGSVTgatckELasQPDVDGFLVGG
* Mouse RgWLksnVNDgVAQstRIIYGGSVTgatckELasQPDVDGFLVGG
* Oryzias_latipes RaWfranISEeVsDsLRIIYGGSVTaaNcrELasQtDVDGFLVGG
* Pongo_pygmaeus RgWLksnVSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGG
* Schistosoma_mansoni RkWfktnapngVdEkIRIIYGGSVTaaNckELaqQhDVDGFLVGG
* Strongylocentrotus_purpuratus RsWLtEhVNaaVAantRIVYGGSVNggNccDIgqQPDVDGFLVGG
* Pig RgWLkthVpEaVAhstRIIYGGSVTgatckELasQPDVDGFrVsG
* Tribolium_castaneum RqWfcthVNadVgnsIRIqYGGSVTgaNckELaaQPDIDGFLVGG
* X_laevis ReWVktnVSEgVAQsVRIIYGGSVTggtcrELagQPDIDGFLVGG
* D_melanogaster-TPIS RqWLsDnISKeVsasLRIqYGGSVTaaNakELakKPDIDGFLVGG
* D_melanogaster-TPIS_VAR RqWLsDnISKeVsasLRIqYGGSVTaaNakELakKPDIDGFLVGG
* Rat-Q6P793 RgWLkcnVSEgVAQctRIIYGGSVTgatckELasQPDVDGFLVGG
* Rat-TPIS RgWLkcnVSEgVAQctRIIYGGSVTgatckELasQPDVDGFLVGG
===============================================================================
ENTAMOEBA_HISTOLYTICA RkWMtEnISKeVAEatRIqYGGSVNpaNcnELakKaDIDGFLVGG
===============================================================================
LEISHMANIA_MEXICANA RkWVsEnIgtdVAakLRILYGGSVNaaNaatLyaKPDINGFLVGG
TRYPANOSOMA_CRUZI RrWVrskLgtdIAaqLRILYGGSVTakNartLyqmrDINGFLVGG
TRYPANOSOMA_BRUCEI RsWVsskIgadVAgeLRILYGGSVNgkNartLyqQrDVNGFLVGG
1KV5A_Trypanosoma_brucei ssWVsskIgadVAgeLRILYGGSVNgkNartLyqQrDVNGFLVGG
1MSSA_Trypanosoma_brucei RsWVsskIgadVAgeLRILYGGSVNgkNartLyqQrDVNGFLVGG
1TRI0_Trypanosoma_brucei RsWVsskIgadVAgeLRILYGGSVNgkNartLyqQrDVNGFLVGG
1TTI0_Trypanosoma_brucei RsWVsskIgadVAgeLRILYGGSVNgkNartLyqQrDVNGFLVGG
1TTJ0_Trypanosoma_brucei RsWVsskIgadVAgeLRILYGGSVNgkNartLyqQrDVNGFLVGG
Leishmania_donovani RkWVsEkIgadVAarLRILYGGSVSagNaktLymKPDINGFLVGG
Leishmania_tropica RkWVsEkIgtdVAakLRILYGGSVSagNaktLymKPDINGFLVGG
===============================================================================
PLASMODIUM_FALCIPARUM RkiVkDtcgEkqAnqIRILYGGSVNteNcssLiqQeDIDGFLVGn
1VGAB_Plasmodium_falciparum RkiVkDtcgEkqAnqIRILYGGSVNteNcssLiqQeDIDGFLVGn
Plasmodium_berghei RkiVkEicgEaqAnkIRILYGGSVSveNctsLikQeDIDGFLVGt
Plasmodium_chabaudi RkiVkEicgEaqAnkIRILYGGSVSveNctsLikQeDIDGFLVGt
===============================================================================
B E_COLI RdhIaKv-DanIAEqViIqYGGSVNasNaaELfaQPDIDGaLVGG
B VIBRIO_MARINUS RahIaEk-SEaVAKnVvIqYGGSVkpeNaaayfaQPDIDGaLVGG
B Actinobacillus_pleuropneumoniae RghIaak-SQaVADqViIqYGGSVNdaNaaELftQPDIDGaLVGG
B Actinobacillus_succinogenes RahIaak-SQaVADqViIqYGGSVNdaNaaELftQPDIDGaLVGG
B Erwinia_carotovora RdhIaKq-DaaVAEqViIqYGGSVNaaNaaELftQPDIDGaLVGG
B Haemophilus_ducreyi RqhIaEk-SQaVADqLiIqYGGSVNdtNaaELfsQPDIDGaLVGG
B Haemophilus_influenzae RghIaak-SQaVAEqViIqYGGSVNdaNaaELftQPDIDGaLVGG
B Histophilus_somni RghIaKq-SQaVAErViIqYGGSVNdaNaaELftQPDIDGaLVGG
B Mannheimia_succiniciproducens RghIaak-SQaVADqViIqYGGSVNdaNaaELftQPDIDGaLVGG
B Pasteurella_multocida RghIaKk-DnaVAEqViIqYGGSVNdaNaaELftQPDIDGaLVGG
B Photobacterium_profundum RahIaEk-SEeVAKnLvIqYGGSVkpeNaaayfaQPDIDGaLVGG
B Photorhabdus_luminescens RdhIaQk-DaaIAQqIiIqYGGSVNadNaaELfsQPDIDGaLVGG
B Vibrio_cholerae RalIaak-DaaVAEqViIqYGGSVkpeNaasyfaQPDIDGaLVGG
B Vibrio_fischeri RahIaEk-SEeVAKnVvIqYGGSVkpeNaaayfaQPDIDGaLVGG
B Vibrio_parahaemolyticus RalIaak-DEaVAaqViIqYGGSVkpeNaeayfsQPDIDGaLVGG
B Vibrio_vulnificus RamIaak-DaaVAEqViIqYGGSVkpeNaeayfaQPDIDGaLVGG
B Yersinia_pestis RdhIaKq-DaaVAaqViIqYGGSVNdkNaaELftQPDIDGaLVGG
B Salmonella_typhi-TPIS RdhIaKa-DakIAEqViIqYGGSVNasNaaELfaQPDIDGaLVGG
B Salmonella_typhi-TPIS_SALTY RdhIaKa-DakIAEqViIqYGGSVNasNaaELfaQPDIDGaLVGG
===============================================================================
B THERMUS_AQUATICUS RkaLsErygEafAsrVRILYGGSVNpkNfaDLlsmPNVDGgLVGG
===============================================================================
B BACILLUS_STEAROTHERMOPHILUS RsvVsrlfgpeaAEaIRIqYGGSVkpdNirDflaQqqIDGpLVGG
B Bacillus_clausii RqtVaanfSEeaAEaIRIqYGGSVkpgNikDymaQPDIDGaLVGG
B Bacillus_halodurans RkvVtEkfSQeaADaVRIqYGGSVkpaNiaEymaQsDIDGaLVGG
B Bacillus_licheniformis RktVasefgQtaADsVRIqYGGSVkpaNikEymaEsDIDGaLVGG
B Bacillus_megaterium RsvVaEqfSQdVADaVRIqYGGSVkpaNikEymsQsDIDGaLVGG
B Bacillus_subtilis RktVaEsfSQeaADkLRIqYGGSVkpaNikEymaEsDIDGaLVGG
B Listeria_monocytogenes-TPIS1 RaeVaDaVSQkaADaVRIqYGGSVkpeNiaDylaEsDIDGaLVGG
B Listeria_monocytogenes-TPIS1_LI RaeVaDaVSQkaADaVRIqYGGSVkpeNiaDylaEsDIDGaLVGG
===============================================================================
Consensus RxyLxexiNexIAExLRIiYGGSVSxxNxxELxxQPDVDGfLVGG
370 380 390 400
----:----|----:----|----:----|----:----|----:
Consensus ASLExpxeFvEIIeAxxxxxxx
========================================================
* S_CEREVISIAE ASLK-P-EFVDIInsrn-----
* Candida_albicans ASLK-P-EFVDIIKsrl-----
* Candida_glabrata ASLK-P-EFVDIInsrn-----
* Debaryomyces_hansenii ASLK-P-EFVDIIKsrl-----
* Eremothecium_gossypii ASLK-P-EFVDIInsrr-----
* Yarrowia_lipolytica ASLK-P-EFVDIInsrl-----
* Zygosaccharomyces_bailii ASLK-P-EFVDIInsrs-----
* Kluyveromyces_lactis-TPIS ASLK-P-EFVDIInsrv-----
* Kluyveromyces_lactis-TPIS_KLUMA ASLK-P-EFVDIInsrv-----
========================================================
* C_ELEGANS ASLK-P-DFVKIInArs-----
* HUMAN ASLK-P-EFVDIInAkq-----
* RABBIT ASLK-P-EFVDIInAkq-----
* CHICKEN ASLK-P-EFVDIInAkh-----
* 1SPQA_Chicken ASLK-P-EFVDIInAkh-----
* 1SPQB_Chicken ASLK-P-EFVDIInAkh-----
* 1SQ7A_Chicken ASLK-P-EFVDIInAkh-----
* 1SSDA_Chicken ASLK-P-EFVDIInAkh-----
* 1SU5A_Chicken ASLK-P-EFVDIInAkh-----
* 1SW3A_Chicken ASLK-P-EFVDIInAkh-----
* 1SW7A_Chicken ASLK-P-EFVDIInAkh-----
* 1TPB1_Chicken ASLK-P-EFVDIInAkh-----
* 1TPC1_Chicken ASLK-P-EFVDIInAkh-----
* 1TPUA_Chicken ASLK-P-EFVDIInAkh-----
* 1TPVA_Chicken ASLK-P-EFVDIInAkh-----
* 1TPWA_Chicken ASLK-P-EFVDIInAkh-----
* Acipenser_brevirostrum ASLK-P-EFIDIInAfq-----
* Anopheles_gambiae ASLK-P-EFIQIVnArq-----
* Bovine ASLK-P-EFVDIInAkq-----
* C_briggsae ASLK-P-DFVKIInArs-----
* Canis_lupus ASLK-P-EFVDIInAkq-----
* Danio_rerio ASLK-P-EFIDIInAka-----
* Gorilla_gorilla ASLK-P-EFVDIInAkq-----
* Latimeria_chalumnae ASLK-P-EFVEykDvrq-----
* Lepisosteus_osseus ASLK-P-EFVEIInArq-----
* Macaca_mulatta ASLK-P-EFVDIInAkq-----
* Mouse ASLK-P-EFVDIInAkq-----
* Oryzias_latipes ASLK-P-EFIDIInAra-----
* Pongo_pygmaeus ASLK-P-EFVDIInAkq-----
* Schistosoma_mansoni ASLK-P-EFtEIcKArqr----
* Strongylocentrotus_purpuratus ASLK-P-EFkQIIaAgsa----
* Pig ASLK-P-EFVDIInAk------
* Tribolium_castaneum ASLK-P-EFVnIVnAkq-----
* X_laevis ASLK-P-EFIEIInAkh-----
* D_melanogaster-TPIS ASLK-P-EFVDIInArq-----
* D_melanogaster-TPIS_VAR ASLK-P-EFVDIInArq-----
* Rat-Q6P793 ASLK-P-EFVDIInAkq-----
* Rat-TPIS ASLK-P-EFVDIInAkq-----
========================================================
ENTAMOEBA_HISTOLYTICA ASLDaa-KFktIInsvsekl--
========================================================
LEISHMANIA_MEXICANA ASLK-P-EFrDIIDAtr-----
TRYPANOSOMA_CRUZI ASLK-P-EFVEIIEAtk-----
TRYPANOSOMA_BRUCEI ASLK-P-EFVDIIKAtq-----
1KV5A_Trypanosoma_brucei ASLK-P-EFVDIIKAtq-----
1MSSA_Trypanosoma_brucei ASLK-P-EFVDIIKAtq-----
1TRI0_Trypanosoma_brucei ASLK-P-EFVDIIKAtq-----
1TTI0_Trypanosoma_brucei ASLK-P-EFVDIIKAtq-----
1TTJ0_Trypanosoma_brucei ASLK-P-EFVDIIKAtq-----
Leishmania_donovani ASLK-P-EFrDIIDAtr-----
Leishmania_tropica ASLK-P-EFrDIIDAtr-----
========================================================
PLASMODIUM_FALCIPARUM ASLK-e-sFVDIIKsam-----
1VGAB_Plasmodium_falciparum ASLK-e-sFVDIIKsam-----
Plasmodium_berghei sSLK-t-sFtEIIKsam-----
Plasmodium_chabaudi sSLK-t-sFtEIIKsam-----
========================================================
B E_COLI ASLKad-aFavIVKAaeaakqa
B VIBRIO_MARINUS AaLDak-sFaaIaKAaaeak-a
B Actinobacillus_pleuropneumoniae ASLKaP-aFavIVKAaekaka-
B Actinobacillus_succinogenes ASLKaP-aFavIVKAaaaaka-
B Erwinia_carotovora ASLKad-aFavIVKAaadakrg
B Haemophilus_ducreyi ASLKat-aFaEIVKAaekaka-
B Haemophilus_influenzae ASLKaP-aFavIVKAaaaakn-
B Histophilus_somni ASLKas-aFavIVKAaakakn-
B Mannheimia_succiniciproducens ASLKaP-aFavIVKAaakaka-
B Pasteurella_multocida ASLKaP-aFavIVKAaakakn-
B Photobacterium_profundum AaLDak-sFaaIaKAaaeaka-
B Photorhabdus_luminescens ASLKan-aFavIVKAaaaakka
B Vibrio_cholerae ASLDak-gFaaIaKAaaeakka
B Vibrio_fischeri AaLDak-sFaaIaKAaaeaka-
B Vibrio_parahaemolyticus ASLDak-sFaaIaKAaaaaka-
B Vibrio_vulnificus ASLDak-sFaaIaKAaakmka-
B Yersinia_pestis ASLKad-aFavIVKAaakakka
B Salmonella_typhi-TPIS ASLKad-aFavIVKAaeaakqa
B Salmonella_typhi-TPIS_SALTY ASLKad-aFavIVKAaeaakqa
========================================================
B THERMUS_AQUATICUS ASLE-lesFLaLLriag-----
========================================================
B BACILLUS_STEAROTHERMOPHILUS ASLE-PasFLQLVEAgrhe---
B Bacillus_clausii ASLD-adsFLELVgAak-----
B Bacillus_halodurans ASLD-PqsFLQLLEAvk-----
B Bacillus_licheniformis ASLE-PqsFVQLLEAgqye---
B Bacillus_megaterium ASLE-adsFLQLLEAgk-----
B Bacillus_subtilis ASLE-PqsFVQLLEegqye---
B Listeria_monocytogenes-TPIS1 ASLE-PasFLaLLEAvk-----
B Listeria_monocytogenes-TPIS1_LI ASLE-PasFLaLLEAvk-----
========================================================
Consensus ASLExpxeFvEIIeAxxxxxxx
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