10 20 30 40 50 60 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus aiRxqFennneIGvfsklTnsycLvaiggsenfyNvfeaelxexipvvhxSIagsriIGrMsvgN ================================================================================================= A METHANOCOCCUS_JANNASCHII iIRkyFsgiptIGVlaltTeeitLLpIfldKDdvNevsevL--etkcLqtNIgGSsLVGsLSVaN ================================================================================================= * S_CEREVISIAE AtRtQFENSNEIGVFSKLTNTYCLVAVGGSENFYSaFEAELgDaIPIVHtTIAGTRIIGRMTaGN * Apis_mellifera AVRvQFENNNEVGVFSKLTNSYCLVAIGGSENFYSVFEAELaEtIPVIHaSVAGcRIIGRLcVGN * Aspergillus_flavus AVRaQFENSNEVGVFaRLTNSYaVVAIGaSENFYSVFEAELqDvIPIcHaTIAGTRIVGRLTaGN * Aspergillus_fumigatus AVRaQFENSNEVGVFaRLTNSYaIVAIGaSENFYSVFEAELqDvIPIcHaTIAGTRIVGRLTaGN * C_briggsae ALRvdYEgSNDVGVFctLTNSYCLVgIGGTQNFYStlEAELsDlIPVVHtSInsTRIVGRLTVGN * C_elegans ALRvdYEgSNDVGVFctLTNSYCLVgVGGTQNFYSIlEAELsDlIPVVHtSIAsTRIVGRLTVGN * Candida_albicans AtRtQFENSNEVGVFSnLTNSYCLVAVGGSENFYSaFEAELgDvIPIVHtTIAGTRIVGRMTsGN * Candida_glabrata AtRtQFENSNEVGVFSKLTNTYCLVAVGGSENFYSaFEAELgDsIPIaHtTIAGTRIVGRMTaGN * Canis_lupus AVRasFENNcEIGcFaKLTNTYCLVAIGGSENFYSVFEgELaDtIPVVHaSIAGcRIIGRMcVGN * Coprinus_cinereus AtRlQFENSSDIGVFSKLTNSYCLVAInGStNFYSaFEsELgDvVPIVHtSIgGTRIVGRLTaGN * Cryptococcus_neoformans AVRtQFENStDIGVFSKLTNSYCLtALasStNFYSVFEAELaDvVPIVHtTIgGTRIIGRLTaGN * Danio_rerio AVRasFEkNNEIGcFaKLTNTYCLVAIGGSENFYSVFEgELsEtMPVIHaSIAGcRIIGRMcVGN * Debaryomyces_hansenii AsRtQFENSNEVGVFSKLTNSYCLVAVGGSENFYSaFEAELgDvIPIVHtTIAGTRIVGRMTaGN * D_melanogaster ALRvQFENNDDIGVFTKLTNTYCLVAIGGSEtFYSaFEAELgDtIPVVHaNVgGcRIIGRLTVGN * D_pseudoobscura ALRvQFENNDDIGVFTKLTNTYCLVAIGGSEtFYSaFEAELaEtIPVVHaNVgGcRIIGRLTVGN * Emericella_nidulans AVRaQFENSNEVGVFSRLTNSYaLVAIGaSENFYSVFEAELqDvIPIcHaTIAGTRIIGRLTaGN * Eremothecium_gossypii AtRtQFENSNEVGVFSKLTNTYCLVtIGGSENFYSaFEAELgDaIPIVHtTIAGTRIVGRMTaGN * Chicken AVRasFENNNELGcFaKLTNaYCLVAIGGSEDFYSVFEgELfgtIPVVHaSIAGcRIIGRMcVGN * Gibberella_zeae AVRaQFENSNEVGVFatLTNSYaLVALGaSENFYSVFEAELqDiVPtVrtTIAGTRIIGRLTaGN * Human AVRasFENNcEIGcFaKLTNTYCLVAIGGSENFYSVFEgELsDtIPVVHaSIAGcRIIGRMcVGN * Kluyveromyces_lactis AtRtQFENSNEIGVFSKLTNSYCLVALGGSENFYSaFEAELgDaIPIaHtTIAGTRIVGRMTaGN * Monodelphis_domestica AVRasFENNcEIGcFaKLTNTYCLVAIGGSENFYSVFEgELsEtIPVVHaSIAGcRIIGRMcVGN * Mouse AVRasFENNcEVGcFaKLTNaYCLVAIGGSENFYSVFEgELsDaIPVVHaSIAGcRIIGRMcVGN * Neurospora_crassa AVRaQFENSNEVGVFStLTNSYaLVAVGaSENFYSVFEAELqDvIPIcrtTIAGTRIIGRLTaGN * Pichia_stipitis AtRtQFENSNEVGVFSKLTNSYnLVAVGGSENFYSaFEAELgDvIPIVHtTIAGTRIVGRMTaGN * Rat AVRasFENNcEVGcFaKLTNTYCLVAIGGSENFYSVFEgELsDtIPVVHaSIAGcRIIGRMcVGN * Schistosoma_japonicum ALRtQFEgHNDIGVFSKLTNkYCLVsVGGSENFYSVFEAELsEnIPVVHtTIAGiRtVGRLTVGN * Schizosaccharomyces_pombe ALRaQFENSNEIGVFSnLTNSYaLVALGGSENFYSVFEAELgDvVPVVHtTIgGTRIIGRLTcGN * Strongylocentrotus_purpuratus ALRtQFESNNDIGVFcKLTNaYCLVAIGGSENFYSLFEgELgDaIPVVHsSInGcRILGsLaaGN * Tribolium_castaneum AfRvQFENNNEIGVFaKLTNaYCLVAIGGSENFYStFEgDfaDtIPVVHaSLAGcRIIGRMcVGN * Ustilago_maydis AVRcQFENSSEIGVFaRLTNaYCLVAIGGSaNFYStFEAELaDvIPVVHcSIAGTRLVGRLTVGN * X_laevis AVRasFENNNEIGcFaKLTNTYCLVAIGGSENFYSVFEgELsEtIPVVHaSIAGcRIIGRMcVGN * X_tropicalis AVRasFENNNEIGcFaKLTNTYCLVAIGGSENFYSVFEgELsEtIPVVHaSIAGcRIIGRMcVGN * Yarrowia_lipolytica AtRaQFENSDEIGVFSKLTNSYCLVAVGGSENFYSsFEAELqDtIPIVysTIgGTRLVGRLTaGN * Bovine-AAF00595 AVRasFENNcEIGcFaKLTNSYCLVAIGGSENFYSVFEgELagtIPVVHaSIAGcRIIGRMcVGN * Bovine-Q9TU47 AVRasFENNcEIGcFaKLTNSYCLVAIGGSENFYSVFEgELagtIPVVHaSIAGcRIIGRMcVGN Bigelowiella_natans AtRasFENSNEIGVFaKLTNSYCLVgtGGSQNFYStFQsELgDhIPVIHaSIgGmRIVGRMvVGN Dictyostelium_discoideum AtRlQYENScDVGVFlKLTNkYCLVgqcGSKqFlHtvEnrLaDhIPVVetSIAGTRIVGRLSaGN Paramecium_tetraurelia AnRcQFENSNDIGVFSKLTNSYCLVALGGSENFYSVFEsELglsMPVIHcSIgGTRIIGRLTaGN Plasmodium_berghei AIRvQFENSNEVGVFSRLTNSYgLIALGGSENFsSVFEAELsQhIPIVyaTIgGTRVIGRVcVGN Plasmodium_chabaudi AIRvQFENSNEVGVFSRLTNSYgLIALGGSENFsSVFEAELsQhIPIVyaTIgGTRVIGRVcVGN Plasmodium_falciparum AIRvQFENSNEVGVFSRLTNSYaLVALGGSENFsSVFEsELsQhIPLVytTIgGTRVIGRVcVGN P Arabidopsis_thaliana AtRlQFENNcEVGVFSKLTNaYCLVAIGGSENFYSaFEsELaDvIPIVktSIgGTRIIGRLcaGN P Oryza_sativa AtRiQFENNcEVGVFSKLTNaYCLVAIGGSENFYSaFEsELaDvIPVVktSIgGTRIIGRLcVGN ================================================================================================= Consensus aiRxqFennneIGvfsklTnsycLvaiggsenfyNvfeaelxexipvvhxSIagsriIGrMsvgN 70 80 90 100 110 120 130 ----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus knGLLVpsstsDqELqhIrNsLpdxsvqIxxqrVEeRlSALGNvixcNDyvaLvhpDLdrdteEi ================================================================================================= A METHANOCOCCUS_JANNASCHII KyGLLLPkiveDEELdrIKNfLkEnNLdLnvEiIKsKnTALGNLIltNDkgALIsPEL-KDfKKd ================================================================================================= * S_CEREVISIAE RrGLLVPTqTTDQELQHLRNSLPD-SVKI--QRVEERLSALGNVIcCNDYVALVHPDIDRETEEL * Apis_mellifera KNGLLVPNTTTDtELQHIRNSLPD-kVKV--QRVEERLSALGNVIaCNDYVALVHPDLDRETEEI * Aspergillus_flavus RkGLLVPTTTTDQELQHLRNTLPD-SVKI--QRIEERLSALGNVIcCNDhVALIHPDLERETEEM * Aspergillus_fumigatus RkGLLVPTTTTDQELQHLRNTLPD-dVKI--QRIEERLSALGNVIcCNDhVALVHPDLERETEEI * C_briggsae RHGLLVPNaTTDQELQHLRNSLPD-eVaI--RRVDERLSALGNVIaCNDhVAIVHaEIsaETEQa * C_elegans RHGLLVPNaTTDQELQHLRNSLPD-eVaI--RRVDERLSALGNVIaCNDhVAIVHaEIsaETEQa * Candida_albicans RrGLLVPTqTTDQELmHLRNSLPD-SIKI--QRVEERLSALGNVIcCNDYVALVHPDIERETEEL * Candida_glabrata RrGLLVPTqTTDQELQHLRNSLPD-SVKI--QRVEERLSALGNVIcCNDYVALVHPDIDRETEEL * Canis_lupus RHGLLVPNNTTDQELQHIRNcLPD-SVQI--RRVEERLSALGNVttCNDYVALVHPDLDRETEEI * Coprinus_cinereus RHGLLVPSTTTDQELQHLRNaLPD-SVsI--QRVEERLSALGNVIaCNDYVALVHPDIDRETEEI * Cryptococcus_neoformans RHGLLVPSSTTDQELQHLRNSLPp-TVaI--QRVEERLSALGNVIaCNDYVALVHPDIDRETEEI * Danio_rerio RHGLLVPNNTTDQELQHIRNcLPD-SVRI--QRVEERLSALGNVIaCNDYVALVHPDLDRETEEI * Debaryomyces_hansenii RrGLLVPTqTTDQELmHLRNSLPD-TVKI--QRVEERLSALGNVIcCNDYVALVHPDIERETEEL * D_melanogaster RNGLLVPNSTTDEELQHLRNSLPD-aVKI--yRVEERLSALGNVIaCNDYVALVHPDLDKETEEI * D_pseudoobscura RNGLLVPNSTTDEELQHLRNSLPD-aVKI--QRVEERLSALGNVVaCNDYVALVHPDLDKETEEI * Emericella_nidulans RkGLLVPTTTTDQELQHLRNTLPD-dVKI--QRIEERLSALGNVIcCNDhVALIHPDLERETEEI * Eremothecium_gossypii RrGLLVPTqTTDQELQHLRNSLPD-SVKI--QRIEERLSALGNVIcCNDYVALVHPDIDnETEEL * Chicken RHGLLVPSSTTDQELQHIRNSLPD-SVRI--QRVEERLSALGNVttCNDYVALVHPDLDRETEEI * Gibberella_zeae RkGLLVPTTTTDQELQHLRNSLPD-SVRI--QRIEERLSALGNVIvtNDhIALVHPDLERETEEI * Human RHGLLVPNNTTDQELQHIRNSLPD-TVQI--RRVEERLSALGNVttCNDYVALVHPDLDRETEEI * Kluyveromyces_lactis RrGLLVPTqTTDQELQHLRNcLPD-aVKV--QRVEERLSALGNVIcCNDYVALVHPDIDRETEEL * Monodelphis_domestica RHGLLVPNNTTDQELQHIRNSLPD-SVQI--RRVEERLSALGNVttCNDYVALVHPDLDRETEEI * Mouse RHGLLVPNNTTDQELQHIRNSLPD-SVQI--RRVEERLSALGNVttCNDYVALVHPDLDRETEEI * Neurospora_crassa RkGLLVPTTTSDQELQHLRNSLPD-dVRI--QRIEERLSALGNVIvCNDhtALIHPDLERETEEI * Pichia_stipitis RrGLLVPTqTTDQELmHLRNSLPD-aVKI--QRVEERLSALGNVIcCNDYVALVHPDIERETEEL * Rat RHGLLVPNNTTDQELQHIRNSLPD-SVQI--RRVEERLSALGNVttCNDYVALVHPDLDRETEEI * Schistosoma_japonicum sHGLLVPhTTTDQELlHLtNSLPD-NIRV--mRIEERLSALGNtMaCNDYVALVHPDLDKETaEL * Schizosaccharomyces_pombe RkGLLVPSSTTDnELQHLRNSLPD-pVKI--QRVDERLSALGNIVaCNDYVALVHPDIERETEEI * Strongylocentrotus_purpuratus RHGLLVPNSTTDQELQHIRNSLPD-SVKI--QRIEEKLSALGNVIsCNDYVALVHPDLEKETEEI * Tribolium_castaneum KNGLLVPNTTfDtELQHIRNaLPD-SVKV--QRVEERLSALGNVIaCNDYVALVHPDLDRETEEI * Ustilago_maydis RHGLLVPSTTTDQELQHLRNSLPE-SVaI--QRVEERLSALGNVIaCNDYVALVHPDLDRETEEI * X_laevis RHGLMVPNNTTDQELQHMRNSLPD-SVRI--QRVEERLSALGNVIaCNDYVALVHPDLDRETEEI * X_tropicalis RHGLMVPNNTTDQELQHIRNSLPD-SVRI--QRVEERLSALGNVIaCNDYVALVHPDLDRETEEI * Yarrowia_lipolytica RrGLLVPSTTSDvELQHLRNSLPD-eVKI--QRVEERLSALGNVIctNDYaALVHPDIERETEEL * Bovine-AAF00595 RHGLLVPNNTTDQELQHIRNcLPD-SVQI--RRVEERLSALGNVttCNDYVALVHPDLDRETEEI * Bovine-Q9TU47 RHGLLVPNNTTDQELQHIRNcLPD-SVQI--RRVEERLSALGNVttCNDYVALVHPDLDRETEEI Bigelowiella_natans KNGLLVPSTTrEnELKHLRNSLPD-kVKV--QRIEEKLSALGNcVvaNDhVALVHPDIDQNTEEL Dictyostelium_discoideum KNGLLLPNTcTDQELQqIRNSLPD-dVvV--QRIEEKfSALGNcIatNDYVALVHPDIDRETEEI Paramecium_tetraurelia KNGLLVPNTcTDQELKqIRNSLPD-eVKV--KRVEEKLSALGNcVaCNDYVALIHsDLDKETEEI Plasmodium_berghei RkGLLVsSicTDQELlHLRNSLPD-NVKI--KRIEERLSALGNcItCNDYVgLIHtDIDRETEEI Plasmodium_chabaudi RkGLLVsSicTDQELlHLRNSLPD-dVKI--KRVEERLSALGNcItCNDYVgLIHtDIDRETEEI Plasmodium_falciparum RkGLLVsSicTDQELlHLRNcLPE-NVKI--KRIEERLSALGNcIttNDYVgLIHtDIDKETEEI P Arabidopsis_thaliana KNGLLVPhTTTDQELQHLRNSLPD-qVvV--QRIDERLSALGNcIaCNDYVALaHtDLDKETEEI P Oryza_sativa KNGLLLPhTTTDQELQHLRNcLPD-qVvV--QRIDERLSALGNcVaCNDhVALtHPDLDKaTEEL ================================================================================================= Consensus knGLLVpsstsDqELqhIrNsLpdxsvqIxxqrVEeRlSALGNvixcNDyvaLvhpDLdrdteEi 140 150 160 170 180 190 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxxxxxxxLaDvLxVEVfrqsVaxnvlvGSycxlSNqGgLvhpqtsiq ================================================================================================= A METHANOCOCCUS_JANNASCHII -------------------------IeDsLnVEVeigTIAelptVGSnavVTNKGcLtHPlvedd ================================================================================================= * S_CEREVISIAE -------------------------IsDVLgVEVFRQTIsgNILVGSYCsLSNQGGLVHPQTSVQ * Apis_mellifera -------------------------LADtLnVEVFRQTVAsNVLVGSYsvLSNQGGLVHPKTSIQ * Aspergillus_flavus yyphhhhcflitiwhgmkvltiftsIADVLgVEVFRQTIAdNVLtGSYmaLSNQGGIVHPKTSIR * Aspergillus_fumigatus -------------------------IADVLgVEVFRQTIAdNVLtGSYmaLSNQGGIVHPKTSIR * C_briggsae -------------------------LvEVLkVEVFRvSLAqNsLVGSYCaLSSnGcLVaaRTppE * C_elegans -------------------------LvEVLkVEVFRvSLAqNsLVGSYCiLSSnGcLVaaRTppE * Candida_albicans -------------------------IADVLgVEVFRQTIAgNVLVGSYCsLSNQGGLVHPQTSIQ * Candida_glabrata -------------------------IsDVLgVEVFRQTIsgNILVGSYCaLSNQGGLVHPQTTIQ * Canis_lupus -------------------------LADVLkVEVFRQTVAdqVLVGSYsvfSNQGGLVHPKTSIE * Coprinus_cinereus -------------------------IADVLkVEVFRQTIAdNVLVGSYCaITNQGGLVHPKTSIQ * Cryptococcus_neoformans -------------------------IADtLkVEVFRQTIAgNVLVGSYCaLSNQGGLVHPKTSrs * Danio_rerio -------------------------LADtLkVEVFRQTVAeqVLVGSYCafSNQGGLVHaKTSIE * Debaryomyces_hansenii -------------------------IADVLgVEVFRQTIAgNVLVGSYCsLSNQGGLVHPQTSIQ * D_melanogaster -------------------------IADVLkVEVFRQTIAdNsLVGSYavLSNQGGMVHPKTSIQ * D_pseudoobscura -------------------------IgDVLnVEVFRQTIAdNtLVGSYtvLSNQGGMVHPKTSIQ * Emericella_nidulans -------------------------IADVLgVEVFRQTIAdNVLtGSYmaLSNQGGIVHPKTSIR * Eremothecium_gossypii -------------------------IADVLgVEVFRQTIsgNVLVGSYCaLSNQGGLVHPQTTIQ * Chicken -------------------------LADVLkVEVFRQTVAdqVLVGSYCvfSNQGGIVHPKTSIE * Gibberella_zeae -------------------------IADVLgVEVFRQTVAdNVLVGSYmsLSNQGGLVHPKTpIQ * Human -------------------------LADVLkVEVFRQTVAdqVLVGSYCvfSNQGGLVHPKTSIE * Kluyveromyces_lactis -------------------------IADVLgVEVFRQTIsgNVLVGSYCaLSNQGGLVHPQTTVQ * Monodelphis_domestica -------------------------LADVLkVEVFRQTVAdqVLVGSYCvfSNQGGLVHPKTSIE * Mouse -------------------------LADVLkVEVFRQTVAdqVLVGSYCvfSNQGGLVHPKTSIE * Neurospora_crassa -------------------------IADVLgVEVFRQTIAdNVLVGSYmaLSNQGGLVHPKTSIQ * Pichia_stipitis -------------------------IADVLgVEVFRQTIAgNVLVGSYCsLSNQGGIVHPQTSIQ * Rat -------------------------LADVLkVEVFRQTVAdqVLVGSYCvfSNQGGLVHPKTSIE * Schistosoma_japonicum -------------------------VsDVLnVDVFRgvVAnqsLVGTYCvLTNQGGLVHPRvTVd * Schizosaccharomyces_pombe -------------------------IADVLdVEVFRQTVAgNVLtGSYCaLSNQGaLVHPRTSIQ * Strongylocentrotus_purpuratus -------------------------IADVLkVEVFRQTVAdNVLVGTYsvISNQGGLVHPKTSVQ * Tribolium_castaneum -------------------------IADtLkVEVFRQTVAnNVLVGSYCvLSNQGGLVHPnTSVv * Ustilago_maydis -------------------------IADVLkVEVFRQTVgdNVLVGSYsaISNQGaLtHPRTSLQ * X_laevis -------------------------LADVLkVEVFRQTIAeqVLVGSYCafSNQGGLLHPKTSIE * X_tropicalis -------------------------LADVLkVEVFRQTIAdqVLVGSYCafSNQGGLLHPKTSIE * Yarrowia_lipolytica -------------------------IADVLgVEVFRQTVAgNVLVGSYCaLSNQGGIVHPQTSIE * Bovine-AAF00595 -------------------------LADVLkVEVFRQkVAdqVLVGSYCvfSNQGGLVHPKTSIE * Bovine-Q9TU47 -------------------------LADVLkVEVFRQTVAdqVLVGSYCvfSNQGGLVHPKTSIE Bigelowiella_natans -------------------------IADVLgVEVFRQaIAkNtLVGSYCaLSNQGcLVHPKTTVp Dictyostelium_discoideum -------------------------IADVLgVEVFRQTVsgNVLVGTYCaLTNQGaLVHPmTSIa Paramecium_tetraurelia -------------------------IADtLgVEVFRtTVAqqVLVGTYCcfNNQGGLVHPlTTVE Plasmodium_berghei -------------------------VqDVLdIEVFRtSIAgNLLVGTYsyfTNnGGLLHamTTsQ Plasmodium_chabaudi -------------------------VqDVLdIEVFRtSIAgNLLVGTYsyfTNnGGLLHamTTsQ Plasmodium_falciparum -------------------------IqDVLdIEVFRtSIAgNLLVGTYsyfTNnGGLLHamTSsQ P Arabidopsis_thaliana -------------------------IADVLgVEVFRQTIAgNILVGSYCaLSNKGGMVHPhTSVE P Oryza_sativa -------------------------IADVLgVEVFRQTIAgNILVGSYCaITNRGGLVHPhTSIE ================================================================================================= Consensus xxxxxxxxxxxxxxxxxxxxxxxxxLaDvLxVEVfrqsVaxnvlvGSycxlSNqGgLvhpqtsiq 200 210 220 230 240 250 260 ----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus dqeeLssLlQVplxvaGTvNRGSdvIgagmvvNdfxafxGldsTatELsVvesvfklxxeaqxps ================================================================================================= A METHANOCOCCUS_JANNASCHII ElEfLkSLfKVeyigkGTaNKGTtsVGAcIIaNskgAvvGgDTTgpELlIIEdalgLi------- ================================================================================================= * S_CEREVISIAE DQEELSSLLQVPL-VAGTVNRGSsVVGAGMVVNDYlAvtGLDTTApELSVIESIFRL-qDAQ-Pe * Apis_mellifera DQDELSSLLQVPL-aAGTVNRGSDVIaAGMVVNDWvsFcGMDTTsTELSVIESVFKL-nEAa-Pa * Aspergillus_flavus DQDELSSLLQVPL-VAGSVNRGSaVVGAGMVVNDWlAvtGLDTTATELSVIESVFRL-gEmg-Pr * Aspergillus_fumigatus DQDELSSLLQVPL-VAGSVNRGSpVVGAGMVVNDWlAvtGLDTTATELSVVESVFRL-gEmg-Pr * C_briggsae tQrELaaLLQIPV-VAGTVNRGSELIGAGMVVNDWvAFcGLDSTsTELSVVESIFKLgeQga-PT * C_elegans tQrEIaaLLQIPV-VAGTcNRGSELIGAGMVVNDWvAFcGLDSTsTELSVVESIFKLgeQga-PT * Candida_albicans DQEELSSLLQVPL-VAGTVNRGSsVVGAGMVVNDWlsvaGLDTTApELSVIESIFRL-qDAQ-Pd * Candida_glabrata DQEELSSLLQVPL-VAGTVNRGSaVVGAGMVVNDYlAvtGLDTTApELSVIESIFRL-qDAQ-Pd * Canis_lupus DQDELSSLLQVPL-VAGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVVESVFKL-nEAQ-PS * Coprinus_cinereus DQDELSSLLQVPL-VAGTVNRGSDVIGAGLVVNDWcAFtGLETTATEISVIEaaFKL-qgqE-sT * Cryptococcus_neoformans ElDELSSLLQVPL-VAGTVNRGSEVIGAGLVVNDWcAFtGLDTTATEVSVIEatFRL-qgqt-sT * Danio_rerio DQDELSSLLQVPL-VAGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVIESVFRL-sEtQ-PS * Debaryomyces_hansenii DQEELSSLLQVPL-VAGTVNRGSaVVGAGMVVNDWlAvtGLDTTApELSVVESIFRL-qDAQ-Pd * D_melanogaster DQDELSSLLQVPL-VAGTVNRGSEVLaAGMVVNDWlsFvGMNTTATEISVIESVFKL-nQAQ-Pa * D_pseudoobscura DQDELSSLLQVPL-VAGTVNRGSEVLaAGMVVNDWlsFvGMNTTATEISVIESVFKL-nQAQ-Pa * Emericella_nidulans DQDELSSLLQVPL-VAGSVNRGSpVVGAGLVVNDWlAvtGLDTTATELSVIESVFRL-gEng-Pg * Eremothecium_gossypii DQEELSSLLQVPL-VAGTINRGSsVVGAGMVVNDYlAvtGLDTTApELSVIESIFRL-qDAn-Pd * Chicken DQDELSSLLQVPL-VAGTVNRGSEVIGAGMVVNDWcAFcGLDTTsTELSVIESIFKL-nEAQ-PS * Gibberella_zeae DQDELSSLLQVPL-VAGSVNRGSNVVGAGMVVNDWlAvtGLDTTATELSVIESVFRL-gEgQgPS * Human DQDELSSLLQVPL-VAGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVVESVFKL-nEAQ-PS * Kluyveromyces_lactis DQEELSSLLQVPL-VAGTVNRGSqVVGAGMVVNDYlAvtGLDTTApELSVIESIFRL-qDAQ-Pe * Monodelphis_domestica DQDELSSLLQVPL-VAGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVVESVFKL-nEAQ-PS * Mouse DQDELSSLLQVPL-VAGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVVESVFKL-nEAK-PS * Neurospora_crassa DQDELSSLLQVPL-VAGSVNRGSNVIGgGMVVNDWmAvtGLDTTApELSVIESVFRLgegAa-Pg * Pichia_stipitis DQEELSSLLQVPL-VAGTVNRGSsVVGAGMVVNDWlAvtGLDTTApELSVIESIFRL-qDAQ-Pe * Rat DQDELSSLLQVPL-VAGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVVESVFKL-nEAK-PS * Schistosoma_japonicum ElDQLSSLLQLPL-tAGTVNRGSpLIaAGLVVNDWagFcGLETTsTEIqVIESIFKL-dgem-ni * Schizosaccharomyces_pombe EQDELSSLLQVPL-VAGTINRGSDVIGAGLVVNDWcAFaGLDTTATELaVcESIFKL-qDAQ-PS * Strongylocentrotus_purpuratus EQnELSSLLQVPL-VAGTVNRGSDVLGgGMVVNDWcAFcGLDTTtaELSVIEkVFKL-sEgQ-Pa * Tribolium_castaneum DlEELSSLLQVPL-VAGTVNRGSEVVGAGLVVNDWtAFaGMDTTsTELSVIESVFKL-sgAa-PS * Ustilago_maydis DQDELSSLLQVPL-VAGTVNRGSDLIGAGLVVNDFaAFcGtDaTATEISVIESVFRL-tgAa-nT * X_laevis DQDELSSLLQVPL-VtGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVIESVFKL-sDAh-PS * X_tropicalis DQDELSSLLQVPL-VtGTVNRGSEVIaAGMVVNDWsAFcGLDTTsTELSVIESVFKL-sDAh-PS * Yarrowia_lipolytica DQDELSSLLQVPL-IAGSVNRGSpVVGAGcVVNDWmAvaGyaTTsfELTVMsSIFKLnnDqQ-ge * Bovine-AAF00595 DQDELSSLLQVPL-VAGTVNRGSEVIaAGMaVNDWcAFcGLDaTsTELSVVESVsKp-nEAQ-PS * Bovine-Q9TU47 DQDELSSLLQVPL-VAGTVNRGSEVIaAGMVVNDWcAFcGLDTTsTELSVVESVFKL-nEAQ-PS Bigelowiella_natans EQKEISSLLQVPV-cAGTVNRGSNVIGAGLVVNDWtAFsGMDTTsTELSVIENIFnL-qDkE-qe Dictyostelium_discoideum DQDELSSLLQVPL-VAGTVNRGNEcVaAGcVVNDWtAivGaDTTATEISVIESIFaL-qgsK-PS Paramecium_tetraurelia ElDELaNLLQIPL-cAGTVNRGSDIIasGLVVNDiaAFcGLDTTsTEITVIEkIFKL-qDkn-kq Plasmodium_berghei EiEELSeLLQIPL-ItGTVNRGSDLIGsGLVaNDWsAFcGMDTTAiELNIIEkIFKL-nniE-dT Plasmodium_chabaudi EiEELSeLLQIPL-ItGTINRGSDLIGsGLVaNDWsAFcGMDTTAiELNIIEkIFKL-nniE-dT Plasmodium_falciparum EiEELSeLLQIPL-ItGTINRGSDLIGsGLVaNDWsAFcGMDTTAiELSIIEkVFKL-nnit-dN P Arabidopsis_thaliana DlEELSTLLQVPL-VAGTVNRGSEVIaAGMtVNDWtsFcGsDTTATELSVIDSIFKL-rEAQ-PS P Oryza_sativa DlDELSTLLQVPL-VAGTVNRGSEVIaAGMtVNDWtAFcGsDTTATELSVIESVFKL-rEgQ-Pa ================================================================================================= Consensus dqeeLssLlQVplxvaGTvNRGSdvIgagmvvNdfxafxGldsTatELsVvesvfklxxeaqxps 270 280 290 300 310 320 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus xixxxsxmxxrnsliesxx =================================================== A METHANOCOCCUS_JANNASCHII ------------------- =================================================== * S_CEREVISIAE sIs-gN-L--RDTLIETys * Apis_mellifera aIt-sT-M--RaSLIESms * Aspergillus_flavus gVgmgS-t-nKeSIVESfy * Aspergillus_fumigatus gLgvgN-a-nKeSIVESfy * C_briggsae sIs-nq-L--RDTLIESml * C_elegans sIs-nq-L--RDTLIESml * Candida_albicans aIg-gN-L--RDTLIETys * Candida_glabrata aIs-gN-L--RDTLIETys * Canis_lupus tIa-tS-M--RDSLIDSlt * Coprinus_cinereus aVi-ge-M--RDSLIDNwa * Cryptococcus_neoformans aVi-ne-M--RDSLIDhya * Danio_rerio aIa-tT-M--RDSLIDSlt * Debaryomyces_hansenii sIs-gN-L--RDTLIETys * D_melanogaster tVt-tk-L--RaaLIEdms * D_pseudoobscura aVt-tk-L--RaaLIEdms * Emericella_nidulans gIg-qg-VanKDSIVESfy * Eremothecium_gossypii aIs-gN-L--RDTLIETys * Chicken tIa-tN-M--RDSLIDSla * Gibberella_zeae nIn-tS-M--KDTMVESfy * Human tIa-tS-M--RDSLIDSlt * Kluyveromyces_lactis aIs-gN-L--RDTLIETys * Monodelphis_domestica aIa-tS-M--RDSLIDr-- * Mouse tIa-tS-M--RDSLIDSlt * Neurospora_crassa qIn-sS-L--KDTMVESfy * Pichia_stipitis sIs-gN-L--RDTLIETys * Rat tIa-tS-M--RDSLIDSlt * Schistosoma_japonicum pVv-gS-a--hDaLVEr-- * Schizosaccharomyces_pombe aIi-sN----RDTLVESyt * Strongylocentrotus_purpuratus aIa-te-M--RDSLVDSlt * Tribolium_castaneum sIt-sk-M--RaSIIESms * Ustilago_maydis gda-vNqL--RDaLVDTya * X_laevis tIa-tS-M--RgSLIDSlt * X_tropicalis tIa-tS-M--RDSLIDSlt * Yarrowia_lipolytica qwe-qT-k--wSqLyQqmg * Bovine-AAF00595 tIa-tS-M--RDSLtDSlt * Bovine-Q9TU47 tIa-tS-M--RDSLIDSlt Bigelowiella_natans kMv-kd-M--QSSLIEdll Dictyostelium_discoideum nIi-nN-I--RNSIVDNv- Paramecium_tetraurelia nMe-vq-I--RqdMMQele Plasmodium_berghei nIe-dT-fkyKSSIVQTmi Plasmodium_chabaudi nIe-dT-fkyKSSIVQTmi Plasmodium_falciparum nMe-dT-fkyKSSIIQTmi P Arabidopsis_thaliana sIv-de-M--RkSLIDTyv P Oryza_sativa aIv-dd-M--RkSLIDSyv =================================================== Consensus xixxxsxmxxrnsliesxx
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