10 20 30 40 50 60 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxLTtxxGAPVxNNQNvITAGpRGPMLLQDLWfLEKLANFDREVIPER ================================================================================================= PROTEUS_MIRABILIS ----------ekkk-----LTTaaGAPVvDNnNVITAGPRGPMLLQDVWFLEKLAHFDREVIPER 1H6NA_Proteus_mirabilis ------------kk-----LTTaaGAPVvDNnNVITAGPRGPMLLQDVWFLEKLAHFDREVIPER 1H7KA_Proteus_mirabilis ------------kk-----LTTaaGAPVvDNnNVITAGPRGPMLLQDVWFLEKLAHFDREVIPER Acinetobacter_calcoaceticus --nd------dtkkcpfsqLTTdfGAPVvDNQNsMTAGaRGPLLaQDLWlnEKLANFvREVIPER Actinobacillus_pleuropneumoniae ----------------------nnGAPVvDNQNsMTAGPRGPLLaQDLWlnEKLANFvREVIPER Actinobacillus_succinogenes seskcpf---hhts-----LTmnnGAPVvDNQNsMTAGPRGPLLaQDLWlnEKLANFvREVIPER Chromobacterium_violaceum ----------rkht-----LTTaaGAPVvDNQNVqTAGPRGPMLLQDVWYLEKLAHFDREVIPER Colwellia_psychrerythraea -----------kkk-----LTTnaGcPVaNNQNVMTAGPRGPqLLQDVWFLEKLAHFDREVIPER Desulfotalea_psychrophila --kd------ekdk-----LTgnnGAPVvDNQNVMTAGPRGPLLLQDVWFMEKLAHFDREVIPER Haemophilus_influenzae -ssqcpfshlaatn-----LTmgnGAPVaDNQNsLTAGPRGPLLaQDLWlnEKLADFvREVIPER Neisseria_gonorrhoeae ttskc-----pvth-----LTmnnGAPVaDNQNsLTAGPRGPLLtQDLWlnEKLADFvREVIPER Nitrosomonas_europaea --dd------akkk-----LTTsaGAPVaDNQNVMTAGPRGPMLLQDIWFLEKLAHFDREVIPER Nitrosomonas_eutropha --dd------skrk-----LTTsaGAPVpDNQNVMTAGPRGPMLLQDVWFLEKLAHFDREVIPER Pasteurella_multocida ----------tnkk-----LTTaaGcPVaHNQNVMTAGPRGPqLLQDVWFLEKLAHFDREVIPER Photorhabdus_luminescens ----------kkrg-----LTTnaGtPVvDNnNVMTAGqRGPMLLQDVWFLEKLAHFDREVIPER Pseudomonas_aeruginosa ---e------ektr-----LTTaaGAPVvDNQNVqTAGPRGPMLLQDVWFLEKLAHFDREVIPER Streptomyces_coelicolor -----pen--nqkp-----LTTvaGAPVpDNQNsLTsGPRGPMLLQDVWFLEKLAHFDREVIPER Vibrio_fischeri -----------skk-----LTTaaGcPVaHNQNVqTAGkRGPqLLQDVWFLEKLAHFDREVIPER Yersinia_pestis ------ms--kkkg-----LTTaaGAPVvDNnNVITAGrRGPMLLQDVWFLEKLAHFDREVIPER ================================================================================================= MICROCOCCUS_LUTEUS --------ehqkttphatgsTrqnGAPavSDRqsLTvGseGPIVLhDthlLEthqHFNRmnIPER ================================================================================================= HELICOBACTER_PYLORI -------------vnkdvkqTTafGAPVwDDnNVITAGPRGPVLLQstWFLEKLAaFDRErIPER ================================================================================================= ENTEROCOCCUS_FAECALIS ---------------knqhLTTsqGsPVgDNQNsLTAGefGPVLIQDVhlLEKLAHFNRErVPER Bacillus_licheniformis -------------ttnknnLTTswGAPVgDNQNsMTAGsRGPtLIQDVhlLEKLAHFNRErVPER Bacillus_subtilis ---------------ssnkLTTswGAPVgDNQNsMTAGsRGPtLIQDVhlLEKLAHFNRErVPER Oceanobacillus_iheyensis -------------snkrntLTTasGAPVgDNQNsITAGhnGPtLLQDfhlLEKLAHFNRErIPER ================================================================================================= Consensus xxxxxxxxxxxxxxxxxxxLTtxxGAPVxNNQNvITAGpRGPMLLQDLWfLEKLANFDREVIPER 70 80 90 100 110 120 130 ----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus RMHAKGSGAYGtFTVxSNDISKYTKAkIFSeVGKKTEMFxRFSTVAGERGAADAERDIRGFALKF ================================================================================================= PROTEUS_MIRABILIS RMHAKGSGAFGTFTV-THDITKYTRAKIFSEVGKKTEMFaRFSTVAGERGAADAERDIRGFALKF 1H6NA_Proteus_mirabilis RMHAKGSGAFGTFTV-THDITKYTRAKIFSEVGKKTEMFaRFSTVAGERGAADAERDIRGFALKF 1H7KA_Proteus_mirabilis RMHAKGSGAFGTFTV-THDITKYTRAKIFSEVGKKTEMFaRFSTVAGERGAADAERDIRGFALKF Acinetobacter_calcoaceticus RMHAKGSGAFGTFTV-THDITQYTRAKIFSEIGKKTEMFaRFTTVAGERGAADAERDIRGFALKF Actinobacillus_pleuropneumoniae RMHAKGSGAFGkFTV-THDITQYTKAaIFSEVGKETELFaRFTTVAGERGAADAERDIRGFAVKF Actinobacillus_succinogenes RMHAKGSGAFGkFTV-TNDITQYTKAaIFSEVGKETELFvRFTTVAGERGAADAERDIRGFAVKF Chromobacterium_violaceum RMHAKGSGAFGTFTV-THDITRYTRAaLFSDIGKKTDLFlRFSTVAGERGAADAERDIRGFAVKF Colwellia_psychrerythraea RMHAKGSGAYGTFTV-THDITQYTRAKIFSEVGKKTEMFaRFTTVAGERGAADAERDIRGFALKF Desulfotalea_psychrophila RMHAKGSGAYGTFTV-TDDIraYTKAKIFaEIGKtTDLFvRFSTVAGERGAADAERDIRGFAMKF Haemophilus_influenzae RMHAKGSGAFGTFTV-THDITKYTRAKIFSEVGKKTEMFaRFTTVAGERGAADAERDIRGFALKF Neisseria_gonorrhoeae RMHAKGSGAFGTFTV-THDITKYTRAKIFSEVGKKTEMFaRFTTVAGERGAADAERDIRGFALKF Nitrosomonas_europaea RMHAKGSGAYGTFTV-THDITRYTRAnIFSQIGKKTDLFvRFSTVAGERGAADAERDIRGFAIKF Nitrosomonas_eutropha RMHAKGSGAYGTFTV-THDITRYTQAKIFSQIGKKTELFvRFSTVAGERGAADAERDIRGFAIKF Pasteurella_multocida RMHAKGSGAYGTFTV-THDITKYTRAKIFSEVGKKTELFaRFTTVAGERGAADAERDIRGFALKF Photorhabdus_luminescens RMHAKGSGAhGvFvV-THDITKYTRAKIFSEIGKKTEMFaRFSTVAGERGAADAERDIRGFALKF Pseudomonas_aeruginosa RMHAKGSaAYGTFTV-THDITpYTRAKIFSQVGKKTDMFlRFSTVAGERGAADAERDIRGFsMRF Streptomyces_coelicolor RMHAKGSGAFGTFTV-THDITRYTsAKIFSEIGKKTpLFtRFSTVAGERGAADAERDIRGFAVKF Vibrio_fischeri RMHAKGSGAYGTFTV-THDITKYTKAKLFSEIGKQTELFaRFTTVAGERGAADAERDIRGFALKF Yersinia_pestis RMHAKGSGAYGTFTV-THDITQYTRAKIFSEIGKKTDMFvRFSTVAGERGAADAERDIRGFAMKF ================================================================================================= MICROCOCCUS_LUTEUS RpHAKGSGAFGeFeV-TeDVSKYTKAlVFqp-GtKTEtllRFSTVAGElGspDtwRDVRGFALRF ================================================================================================= HELICOBACTER_PYLORI vVHAKGSGAYGTFTV-TkDITKYTKAKIFSKVGKKTEcFfRFSTVAGERGsADAvRDpRGFAMKY ================================================================================================= ENTEROCOCCUS_FAECALIS vVHAKGaGAhGiFkV-SqsMaQYTKAdflSEVGKETpLFaRFSTVAGElGssDtlRDpRGFALKF Bacillus_licheniformis vVHAKGaGAhGyFeV-TNDVSKYTKAKflSEVGKRTpLFvRFSTVAGEnGsADsvRDpRGFAVKF Bacillus_subtilis vVHAKGaGAhGyFeV-TNDVTKYTKAaflSEVGKRTpLFiRFSTVAGElGsADtvRDpRGFAVKF Oceanobacillus_iheyensis vVHAKGaGAhGyFeVtNDEISKYTKAdflSEkGKRTDMFiRFSTVAGEQGsADtvRDpRGFAVKF ================================================================================================= Consensus RMHAKGSGAYGtFTVxSNDISKYTKAkIFSeVGKKTEMFxRFSTVAGERGAADAERDIRGFALKF 140 150 160 170 180 190 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus YTEEGNWDMVGNNTPVFYLRDPLKFPDLNhaVKRNPQTNMRNaxxnWDFFSxLPEaLHQLTIlMS ================================================================================================= PROTEUS_MIRABILIS YTEEGNWDMVGNNTPVFYLRDPLKFPDLNHiVKRDPRTNMRNmaykWDFFShLPEsLHQLTIdMS 1H6NA_Proteus_mirabilis YTEEGNWDMVGNNTPVFYLRDPLKFPDLNHiVKRDPRTNMRNmaykWDFFShLPEsLHQLTIdMS 1H7KA_Proteus_mirabilis YTEEGNWDMVGNNTPVFYLRDPLKFPDLNHiVKRDPRTNMRNmaykWDFFShLPEsLHQLTIdMS Acinetobacter_calcoaceticus YTEEGNWDMVGNNTPVFFLRDPrKFPDLNkAVKRDPKTNLRSAtnNWDFWTlLPEALHQVTIVMS Actinobacillus_pleuropneumoniae YTEQGNWDfVGNNTPVFFLRDPrKFPDLNkAVKRDPRTNMRSAtnNWDFWTlLPEAfHQVTIVMS Actinobacillus_succinogenes YTEQGNWDLVGNNTPVFFLRDPrKFPDLNkAVKRDPRTNMRSAnnNWDFWTlLPEALHQVTIVMS Chromobacterium_violaceum YTEEGNWDLVGNNTPVFFLRDPLKFPDLNrAVKRNPyTNMRDAnaNWDFWTlLPEALHQVTIVMS Colwellia_psychrerythraea YTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSAqnNWDFWTsLPEALHQITIVMS Desulfotalea_psychrophila YTEEGNWDLVGNNTPVFFLKDPLKFPDLNHAVKRDPRTNMRSAanNWDYWSsLPEALHQVTItMS Haemophilus_influenzae YTEEGNWDLVGNNTPVFFLRDPrKFPDLNkAVKRDPRTNMRSAtnNWDFWTlLPEALHQVTVVMS Neisseria_gonorrhoeae YTEEGNWDVVGNNTPVFFLRDPrKFPDLNkAVKRDPRTNMRSAtnNWDFWTlLPEALHQVTIVMS Nitrosomonas_europaea YTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNLRSArnNWDFWTlLPEALHQITIVMS Nitrosomonas_eutropha YTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNLRSArnNWDFWTlLPEALHQITIVMS Pasteurella_multocida YTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSstnNWDFWTsLPEAfHQVTIVMS Photorhabdus_luminescens YTEEGNWDLVGNNTPIFYLRDPLKFPDLNHvVKRDPhTNLRNpaykWDFFShqPEsLHQLTIdfS Pseudomonas_aeruginosa YTEQGNWDLVGNNTPVFYLRDPLKFPDLNHvVKRDPRTNLRNAtfkWDFFShLPEsLHQLTIdfS Streptomyces_coelicolor YTDEGNWDLVGNNTPVFFfRDPLKFPDLNHAVKRDPRTNLRNAenNWDFWTnLPEALHQVTIVMS Vibrio_fischeri YTEEGNWDLVGNNTPVFFLRDPLKFPDLNHAVKRDPRTNMRSAknNWDFWTsLPEALHQVTIVMS Yersinia_pestis YTEEGNWDLVGNDTPVFYLRDPLKFPDLNHvVKRDPRTNLRNpvykWDFFSqLPEALHQLTIdfS ================================================================================================= MICROCOCCUS_LUTEUS YTEEGNYDLVGNNTPIFFLRDPMKFthfirsqKRlPdSgLRDAtmqWDFWTnnPEsaHQVTyLMg ================================================================================================= HELICOBACTER_PYLORI YTEEGNWDLVGNNTPVFFIRDaIKFPDfiHtqKRDPQTNLpNhdmvWDFWSnVPEsLyQVTwVMS ================================================================================================= ENTEROCOCCUS_FAECALIS YTDEGNYDLVGNNTPIFFIRDaIKFPDfiHsqKRNPRTHLKSpeavWDFWShsPEsLHQVTILMS Bacillus_licheniformis YTEEGNYDLVGNNTPVFFIRDaIKFPDfiHtqKRHPvTHLKNpdavWDFWSlsPEsLHQVTILMS Bacillus_subtilis YTEEGNYDIVGNNTPVFFIRDaIKFPDfiHtqKRDPKTHLKNptavWDFWSlsPEsLHQVTILMS Oceanobacillus_iheyensis YTEEGNYDLVGNNTPIFFIRDaIKFPDfiHtqKRNPQTHLKDkdmvWDFWSlsPEsLHQVTyLhS ================================================================================================= Consensus YTEEGNWDMVGNNTPVFYLRDPLKFPDLNhaVKRNPQTNMRNaxxnWDFFSxLPEaLHQLTIlMS 200 210 220 230 240 250 260 ----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus DRGLPaSFRHVNGYGSHTYSfINaexERYWVKFHYRTQQGIQNLsDeEAekLvgeDRESNQQDLF ================================================================================================= PROTEUS_MIRABILIS DRGLPlSYRfVHGFGSHTYSFINkDnERFWVKFHFRcQQGIKNLmDDEAEaLVGKDRESSQRDLF 1H6NA_Proteus_mirabilis DRGLPlSYRfVHGYGSHTYSFINkDnERFWVKFHFRcQQGIKNLmDDEAEaLVGKDRESSQRDLF 1H7KA_Proteus_mirabilis DRGLPlSYRfVHGFGSHTYSFINkDnERFWVKFHYRcQQGIKNLmDDEAEaLVGKDRESSQRDLF Acinetobacter_calcoaceticus DRGIPASYRHMHGFsSHTYSFINsvnERFWVKFHFRTQQGIKNLTDaEAgELVGhDRESHQRDLF Actinobacillus_pleuropneumoniae ERGIPASYRHMHGYGSHTYSlINAnnERFWVKFHFRTEQGIKNLTNEEAaaIIanDRESHQRDLY Actinobacillus_succinogenes ERGIPASYRHMHGFGSHTYSmINAhnERFWVKFHFRTQQGIKNLTNEEAaaIIanDRESHQRDLY Chromobacterium_violaceum DRGIPASYRHMHGFGSHTFSlINAKgERhWVKFHFhTQQGIRNLSDaEAEKLVGQDRESaQRDLl Colwellia_psychrerythraea DRGLPATYRHMHGFGSHTFSmINADnERvWVKFHFeSnQGIQNLTDQEAEvVIGQNRESHhaDLY Desulfotalea_psychrophila DRGIPlSYRHMNGYGSHTYSlLNennERFWVKFHFKTQQGIKtLSDEEAEKLVGrDRESHQRDLl Haemophilus_influenzae DRGIPASYRHMHGFGSHTYSFwNeagERFWVKFHFRTQQGIKNLTDaEAaEIIanDRESHQRDLY Neisseria_gonorrhoeae DRGIPASYRHMHGFGSHTYSFwNeagERFWVKFHFRSQQGIKNLTNEEAaKIIaDDRESHQRDLY Nitrosomonas_europaea DRGLPATYRHMHGFGSHTFSFINArqERYWVKFHFRTQQGIKNLTDaEAEaLVGKDRESHQRDLY Nitrosomonas_eutropha DRGIPtTYRHMHGFGSHTFSFLNAQrERYWVKFHFRTQQGIKNLTDaEAEtLIGEDRESHQRDLY Pasteurella_multocida DRGIPASYRHMHGFGSHTFSFINAEnERYWVKFHFKTQQGIKNIgDEEAQlLaGKDRESHhRDLY Photorhabdus_luminescens DRGVPkSFRHMHGFGSHTFSFINADnERFWVKFHFRcQQGIKNLmDEEAEaLVGKDRESSQRDLF Pseudomonas_aeruginosa DRGLPkSYRHIHGFGSHTFSFINAnnERFWVKFHFKTQQGIENLTNaEAaEVIaQDRESSQRDLY Streptomyces_coelicolor DRGIPASYRHMHGFGSHTYSlINAEgERFWVKFHhRTQQGIKNLTDaEAEaLVGKDRESHQRDLF Vibrio_fischeri DRGIPATYRHMHGFGSHTFSFINsDnERFWVKFHFKSQQGIKNLSDaEAaQVIGQDRESHQRDLl Yersinia_pestis DRGLPkSYRHMHGFGSHTFSlINAnnERFWVKFHFRcQQGIENLmDDEAEKLIGsDRESSQRDLY ================================================================================================= MICROCOCCUS_LUTEUS pRGLPrTWReMNGYGSHTYlWVNAQgEKhWVKYHFiSQQGVhNLSNDEAtKIaGENaDfHRQDLF ================================================================================================= HELICOBACTER_PYLORI DRGIPkSFRHMDGFGSHTFSlINAKgERFWVKFHFhTmQGVKHLTNEEAaEIrkhDpDSNQRDLF ================================================================================================= ENTEROCOCCUS_FAECALIS DRGIPlSFRHMHGFGSHTFkWVNAagEvFFVKYHFKTnQGIKNLesQlAEEIaGKNpDfHiEDLh Bacillus_licheniformis DRGIPATYRHMHGFGSHTFkWVNAEgEgvWIKYHFKTEQGIKNLTEEvgtKIaGENpDyHtQDLY Bacillus_subtilis DRGIPATlRHMHGFGSHTFkWtNAEgEgvWIKYHFKTEQGVKNLdvntAaKIaGENpDyHtEDLF Oceanobacillus_iheyensis DRGLPATlRHMNGYGSHTFkWVNAEgEaFWVKYHFiSEQGIKNLdpalADKIaGENpDyHtEDLF ================================================================================================= Consensus DRGLPaSFRHVNGYGSHTYSfINaexERYWVKFHYRTQQGIQNLsDeEAekLvgeDRESNQQDLF 270 280 290 300 310 320 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus daIEqGDYPkWxLyIQIMPExEAexxpYNPFDLTKVWpxqDYPLMEVGxmELNRNPENYFAEVEQ ================================================================================================= PROTEUS_MIRABILIS EAIERGDYPRWkLqIQIMPEkEAstvPYNPFDLTKVWPhaDYPLMDVGyfELNRNPDNYFsDVEQ 1H6NA_Proteus_mirabilis EAIERGDYPRWkLqIQIMPEkEAstvPYNPFDLTKVWPhaDYPLMDVGyfELNRNPDNYFsDVEQ 1H7KA_Proteus_mirabilis EAIERGDYPRWkLqIQIMPEkEAstvPYNPFDLTKVWPhaDYPLMDVGyfELNRNPDNYFsDVEQ Acinetobacter_calcoaceticus DAIERkDFPKWtLYVQVMPEqDAEkvPYHPFDLTKVWPhgDYPLIEVGefELNRNPENFFlDVEQ Actinobacillus_pleuropneumoniae EsIEKGDFPKWkLYIQVMPEaEAEqvdFHPFDLTKIWskKDYPLIEVGvMELNRNPaNFFADVEQ Actinobacillus_succinogenes EsIEnGDFPRWtLYIQVMPEtDAEnvPYHPFDLTKVWPkKDYPLIEVGvMELNRNPaNFFADVEQ Chromobacterium_violaceum EcIDRGDFPRWtLYIQVMtEaQADacPFNPFDLTKVWshKDYPLIEVGvLELNRNPQNYFADVEQ Colwellia_psychrerythraea DsLEsGDFPsWtLkIQVMtEeQAEksPYNPFDLTKVWPhKDYPLIEVGvMELNRNPENFFAEVEQ Desulfotalea_psychrophila EAIDnhEFPsWkMqIQVVPEkEAanfPFNPFDLTKVWPhdDYPLIDVGiMELNKNPENYFAEVEQ Haemophilus_influenzae EAIERGDFPKWtLFVQIMPEaDAEkvPYHPFDLTKVWskKDYPLIEVGefELNRNPENFFADVEQ Neisseria_gonorrhoeae EAIERGEFPKWtMYIQVMPEaDAEkvPYHPFDLTKVWPkKDYPLIEVGefELNRNPENFFADVEQ Nitrosomonas_europaea EsIEnGEFPRWtLFVQIMPEsDAaslPYNPFDLTKVWPhKDYPLIEVGvMELNRNPENYFAEVEQ Nitrosomonas_eutropha EsIERGEFPRWtLFVQIMPEsDvadlsYNPFDLTKVWPhKDYPLIEVGvMELNRNPENYFAEVEQ Pasteurella_multocida EsIERqDFPKWkMYVQIMPElEADevnFNPFDLTRVWsqKDYPLIpVGefELNRNPENFYAEVEQ Photorhabdus_luminescens aAIEQGDYPRWkLkVQIMPEkEAnllPYNPFDLTKVWPhgDYPMIDVGyfELNRNPDNYFsDVEQ Pseudomonas_aeruginosa EsIEKGDFPRWkMYVQIMPEkEAatyrYNPFDLTKVWPhgDYPLIEVGffELNRNPDNYFAEVEQ Streptomyces_coelicolor DAIEdGDFPKWkLFIQVMPEaDAEnyrFHPFDLTKVWskKDYPLIEVGewELNRNPDNYFADVEQ Vibrio_fischeri EsIDnqDFPKWtLkVQIMPEaDAatvPYNPFDLTKVWPhKDYPLIEVGefELNRNPQNFFAEVEQ Yersinia_pestis EAIERGDFPRWkLqIQVMPEhEAsqtPYNPFDLTKVWPhgDYPLIDVGyfELNRNPENYFAEVEQ ================================================================================================= MICROCOCCUS_LUTEUS EsIaKGDhPKWdLYIQaIPyeEgKtyrFNPFDLTKtisqKDYPrIKVGtLtLNRNPENhFAQIEs ================================================================================================= HELICOBACTER_PYLORI NAIaRGDYPKWkLsIQVMPEeDAKkyrFHPFDVTKIWytQDYPLMEVGiVELNKNPENYFAEVEQ ================================================================================================= ENTEROCOCCUS_FAECALIS NAIEnqEFPsWtLsVQIIPyaDAltmketlFDVTKtvsqKEYPLIEVGtMtLNRNPENYFAEVEQ Bacillus_licheniformis EAIEKGDFPaWkLYVQIMPleDADtyrFDPFDVTKVWsqKDYPLIEVGrMvLNRNPENYFAEVEQ Bacillus_subtilis NAIEnGDYPaWkLYVQIMPleDAntyrFDPFDVTKVWsqKDYPLIEVGrMvLDRNPENYFAEVEQ Oceanobacillus_iheyensis NAIEEGDhPaWkLYVQIMPyeDAKtykWDPFDVTKIWskKDYPrIEVGrMvLDRNPENYFAEVEQ ================================================================================================= Consensus daIEqGDYPkWxLyIQIMPExEAexxpYNPFDLTKVWpxqDYPLMEVGxmELNRNPENYFAEVEQ 330 340 350 360 370 380 390 ----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus aAFSPaSIVPGIsfSPDKMLQGRLFsYgDAqRYRLGVNhhQIPVNapKCPvHNxyhRDGxMQixD ================================================================================================= PROTEUS_MIRABILIS AAFSPANIVPGISFSPDKMLQGRLFSYGDAhRYRLGVNHHQIPVNAPKCPfHN-YHRDGaMRV-D 1H6NA_Proteus_mirabilis AAFSPANIVPGISFSPDKMLQGRLFSYGDAhRYRLGVNHHQIPVNAPKCPfHN-YHRDGaMRV-D 1H7KA_Proteus_mirabilis AAFSPANIVPGISFSPDKMLQGRLFSYGDAhRYRLGVNHHQIPVNAPKCPfHN-YHRDGaMRV-D Acinetobacter_calcoaceticus sAFaPsNLVPGISaSPDRMLQaRLFNYaDAQRYRLGVNyqQIPVNAaRCPVHS-nHRDGqgRI-D Actinobacillus_pleuropneumoniae sAFaPsNLVPGISvSPDRMLQaRLFNYaDAQRYRLGVNHHQIPVNAPRCPVHS-naRDGqsRV-D Actinobacillus_succinogenes sAFaPsNLVPGISvSPDRMLQaRLFNYaDAQRYRLGVNfNQIPVNAPRCPVHS-naRDGqgRV-D Chromobacterium_violaceum AAFNPANVVPGISFSPDRMLQGRLFaYGDAERYRLGVNHHlIPVNAPRCPfHNsYHRDGaMRV-D Colwellia_psychrerythraea sAFNPASIVPGISFSPDKMLQGRLFSYGDAQRYRLGVNHqQIPVNAPRCPVHS-YHRDGaMRV-D Desulfotalea_psychrophila AAFNPANIVPGIgFSPDKMLQGRLFSYGDAQRYRLGVNHHlIPVNraRCPfHS-FHRDGaMRV-D Haemophilus_influenzae sAFaPsNLVPGIgaSPDRMLQaRLFNYaDAQRYRLGVNyrQIPVNrPRCPVHS-nqRDGqgRV-D Neisseria_gonorrhoeae sAFaPsNLVPGIgaSPDKMLQaRLFNYaDAQRYRLGVNfrQIPVNrPRCPVHS-nqRDGqgRa-D Nitrosomonas_europaea AAFNPASVVPGISFSPDKMLQGRLFSYGDAQRYRLGVNHyQIPVNAPRCPfHH-YHRDGaMRV-D Nitrosomonas_eutropha AAFNPANVIPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNAPRCPfHN-YHRDGtMRV-D Pasteurella_multocida sAFNPAaIVPGIgFSPDKMLQGRLFaYGDAQRYRLGVNHHQIPVNAPRCPVHS-YHRDGaMRV-D Photorhabdus_luminescens AAFNPANVVPGISFSPDKMLQGRLFSYGDAQRYRLGVNHHQIPVNtPRCPfHN-YHRDGaMRV-D Pseudomonas_aeruginosa AAFTPANVVPGIgFSPDKMLQGRLFSYGDAhRYRLGVNHHQIPVNAaRCPhqv-YHRDGgMRV-D Streptomyces_coelicolor AAFSPANVVPGISFSPDRMLQGRLFSYGDAQRYRLGVNHHQIPVNAPKnPVNS-YHRDGaMRV-D Vibrio_fischeri sAFNPANVVPGISFSPDKMLQGRLFaYGDAQRYRLGVNHqhIPVNAPRCPVHS-YHRDGaMRV-D Yersinia_pestis ssFNPANVVPGISFSPDRMLQGRLFSYGDAaRYRLGVNHHQIPVNsaKCPfHN-YHRDGaMRV-D ================================================================================================= MICROCOCCUS_LUTEUS AAFSPsNtVPGIglSPDRMLlGRaFaYhDAQlYRVGaHvNQLPVNrPKnaVHN-YafEGqMwy-D ================================================================================================= HELICOBACTER_PYLORI AAFTPANVVPGIgYSPDRMLQGRLFSYGDthRYRLGVNypQIPVNkPRCPfHS-ssRDGyMQn-- ================================================================================================= ENTEROCOCCUS_FAECALIS vtFSPgNfVPGIeaSPDKLLQGRLFaYGDAhRhRVGaNsHQLPINqaKaPVNN-YqKDGnMRf-N Bacillus_licheniformis AtFSPgTLVPGIepSPDKMLQGRLFaYaDAhRYRVGaNHNsLPINrPKaeVHN-YqRDGqMRf-D Bacillus_subtilis AtFSPgTLVPGIdvSPDKMLQGRLFaYhDAhRYRVGaNHqaLPINraRnkVNN-YqRDGqMRfgD Oceanobacillus_iheyensis AAFSPgqfVPGIeaSPDKMLQGRLFgYsDAhRYRLGaNHHsIPVNrPKneVNN-YqRDGfMsV-D ================================================================================================= Consensus aAFSPaSIVPGIsfSPDKMLQGRLFsYgDAqRYRLGVNhhQIPVNapKCPvHNxyhRDGxMQixD 400 410 420 430 440 450 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus xgHxGNxsixYEPNSfgqfqeepefxexxPplxIxxxxxdGxAxNWNxxrxexdxxexDxYFSQP ================================================================================================= PROTEUS_MIRABILIS -GNsGN-gItYEPNSgGvFQEQPDFkE--PPLsI-----EGaAdHWNh-R-E-D--E-D-YFSQP 1H6NA_Proteus_mirabilis -GNsGN-gItYEPNSgGvFQEQPDFkE--PPLsI-----EGaAdHWNh-R-E-D--E-D-YFSQP 1H7KA_Proteus_mirabilis -GNsGN-gItYEPNSgGvFQEQPDFkE--PPLsI-----EGaAdHWNh-R-E-D--E-D-YFSQP Acinetobacter_calcoaceticus -aNyGg-lphYEPNSFGQWQEQPQYkE--PPLkI-----NGdAdfWNy-R-E-D--DnD-YFSQP Actinobacillus_pleuropneumoniae -GNyGS-TLhYEPNSFGQWQEQaQFaE--PPLkI-----NGdAafWDy-R-Q-D--DsD-YFSQP Actinobacillus_succinogenes -GNyGS-TIhYEPNSFGQWQEQaQFaE--PPLkI-----NGdAaHWDy-R-EnD--s-D-YFSQP Chromobacterium_violaceum -sNaGa-TIgYEPNSqGKWQQQPaYdE--PPLaL-----qGnAyHYDf-RaD-D--D-D-YYSQP Colwellia_psychrerythraea -GNhGS-TIgYEPNTqGEWQEQPDFsE--PPMeL-----sGaAaHWNh-R-E-D--E-D-YFSQP Desulfotalea_psychrophila -GNyGg-TrgYEPNSYGEWREQPEFkE--PPLtL-----EGaAdHWNh-R-E-Ds-D-D-YYSQP Haemophilus_influenzae -GNyGS-lphYEPNSFsQWQQQPDFaE--PPLrI-----NGdAaHWDy-RnD-D--n-D-YFSQP Neisseria_gonorrhoeae -GNyGS-lphYEPNSFGQWQQQPDFaE--PPLkI-----NGdAaHWDyrQ-D-D--D-D-YFSQP Nitrosomonas_europaea -GNqGS-TLgYEPNSYqEWQQQPEYaE--PPLtL-----EGaAaHWNh-R-v-D--E-D-YYiQP Nitrosomonas_eutropha -GNhdS-TLgYEPNSYqEWQQQPgYaE--PPLaL-----EGsAaHWNh-R-E-D--g-D-YYTQP Pasteurella_multocida -GNfGS-TLgYEPNykqEWaEQPDYsE--PPLrI-----sGhAdHYDh-R-v-D--E-D-YFSQa Photorhabdus_luminescens -GNsGN-TVtYEPNNaGlFQEQPEFkh--PsLsL-----EGdAdHWNh-R-Q-D--E-D-YFSQP Pseudomonas_aeruginosa -GNnaHqrVtYEPNSFnQWQEQPDFsE--PPLsL-----EGaAdHWNh-R-v-D--D-D-YYSQP Streptomyces_coelicolor -GNqGa-TpgvEPNSYGRWQEQPaYrD--PaqaV-----gavAdrFNy-R-E-D--D-DnYFeQP Vibrio_fischeri -GNfGS-TLgYEPNNeGQWaEQPDFaE--PaLnL-----DGaAaHWDh-R-E-D--E-D-YFSQP Yersinia_pestis -GNsGN-gatYEPNSFGlFQEQPDFsE--PPLtL-----EGaAdHWNh-R-E-D--t-D-YFSQP ================================================================================================= MICROCOCCUS_LUTEUS --HtGD-rstYvPNSn-gdswsdEtgpvddgwea-----DGtltreaqa---lradD-D-dFgQa ================================================================================================= HELICOBACTER_PYLORI -GyyGS-lqnYtPSSlpgYKEDksarD--PkfnLahiekEfevwNWDyr--adD--s-D-YYTQP ================================================================================================= ENTEROCOCCUS_FAECALIS --NgnS-eInYEPNSYtEtpKEdptaKi-ssfeV-----EGnvgNYSy----n---Q-D-hFTQa Bacillus_licheniformis s-NgGg-SVyYEPNSF-ggpQEtpenKt-taypV-----sGsAdStay----d---hnD-hYTQa Bacillus_subtilis --NgGg-SVyYEPNSF-ggpKEspedKq-aaypV-----qGiAdSvSy----d---hyD-hYTQa Oceanobacillus_iheyensis g-NgGN-kpnYEPNS-vngptEdseaKi-nPfeI-----yGqAdSvty----ds--D-D-hYTQa ================================================================================================= Consensus xgHxGNxsixYEPNSfgqfqeepefxexxPplxIxxxxxdGxAxNWNxxrxexdxxexDxYFSQP 460 470 480 490 500 510 520 ----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus gxLYrxLLSxeERExMFDntAxxLxeaxxeeIQxRhIxhxxkxNpaYGeGVaExxxxAIxxxxxx ================================================================================================= PROTEUS_MIRABILIS raLYe-LLSdDEhQrMFariAgeLsQA-sKEtQqRqIdlftKvHPeYGaGVeK----AI-----k 1H6NA_Proteus_mirabilis raLYe-LLSdDEhQrMFariAgeLsQA-sKEtQqRqIdlftKvHPeYGaGVeK----AI-----k 1H7KA_Proteus_mirabilis raLYe-LLSdDEhQrMFariAgeLsQA-sKEtQqRqIdlftKvHPeYGaGVeK----AI-----k Acinetobacter_calcoaceticus raLFe-LMTpEQQQaLFDNTeraMgDA-lDfIKyRHIrNcyacHPAYGEGVAK----AL-----g Actinobacillus_pleuropneumoniae raLFn-LMTeKEKQsLFkNTAegMgDA-lDfIKyRHIrNcyfcDPAYGEGVAK----ALgmtvad Actinobacillus_succinogenes rtLFn-LMTeKERQsLFNNTAdaMgDA-lDfIKyRHIrNcyfcDPAYGEGVAK----AL-----r Chromobacterium_violaceum GaLFR-LMTpaQQQaLFDNTAraMggv-dEaIKrRHIaNcaKaDPAYGaGVAK----AL-----g Colwellia_psychrerythraea GdLFR-LMdnsQQQaLFDNTArsVggA-siDIQkRHIsHclKaDqAYGaGVAK----AL-----g Desulfotalea_psychrophila GnLFR-LMTaEQKKvLFENTAraLgDA-praIKmRHasNcqKaDrAYGEGVAm----AL-----g Haemophilus_influenzae raLFn-LMNaEQKQsLFNNTAaaMgDA-pDfIKyRHIrNchwcDaAYGEGVAK----ALgltved Neisseria_gonorrhoeae raLFn-LMNdaQKQaLFDNTAaaMgDA-pDfIKyRHIrNcyRcDPAYGEGVAK----AL-----g Nitrosomonas_europaea GnLFR-LMNssQQQvLFDNTArsIgEA-prEIQiRHItNclKaDrAYGEGVAr----AL-----g Nitrosomonas_eutropha GnLFR-LMSpaQQQiLFDNTAraIgEA-srEsQlRHIiHclnaDrAYaEGVAr----AL-----e Pasteurella_multocida GdLFR-LMNeEQRQaLFDNTAraMdgv-pDfIKeRHVtHayQaDeAYGKGLel----AL-----g Photorhabdus_luminescens rkLFm-LINsKEhQrMFDriAseLsQA-hEDtQrRqVelfrKvHPeYGaGVen----AL-----k Pseudomonas_aeruginosa aaLFh-LfTdEQKQrLFaNiAedIrDv-pEQIQrRqIglflKvDPAYGKGVAD----AL-----g Streptomyces_coelicolor GnLFR-qMSpEQQQvLFENTAraIdgA-saQtieRHIgNctQaDPAYGaGVrK----AI-----e Vibrio_fischeri GdLFR-LMTaEQQaiLFDNTArnLngv-pKEIQlRHLrHcyKaDPAYGEGIgK----lL-----d Yersinia_pestis raLFn-LLSeEEhQrMFtriAgeLsQv-pEaIQrRqIalftQvDPAYGaGVkK----AL-----g ================================================================================================= MICROCOCCUS_LUTEUS GtLvReVfSdQERDdfvEtvAgaLkgvr-QDVQaRafeywknvDatiGQrIeD----eV-----k ================================================================================================= HELICOBACTER_PYLORI GdyYR-sLpaDEKErLhDtigesLahvthKEIvdKqLeHfkKaDPkYaEGVkK----AL-----e ================================================================================================= ENTEROCOCCUS_FAECALIS naLYn-LLpsEEKEnLiNNiAasLgQvknQEIiaRqIdlftRvNPeYGarVAQ----AI-----k Bacillus_licheniformis GdLYR-LLSeEERtrLvsNivgsMkQvtkDEIKlRqIqHfyKaDPeYGtrVAE----gL-----g Bacillus_subtilis GdLYR-LMSeDERtrLvENivnaMkpvekEEIKlRqIeHfyKaDPeYGKrVAEglglpI-----k Oceanobacillus_iheyensis GdLYR-LMSaDEKDrLvEafvghMtpvtkDEIKlRqIeHiyKaDaeWGErVAQ----gL-----g ================================================================================================= Consensus gxLYrxLLSxeERExMFDntAxxLxeaxxeeIQxRhIxhxxkxNpaYGeGVaExxxxAIxxxxxx 530 540 550 560 570 580 ----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus vxxxxxxxxxxxxxxxxxxxxxxxxxx =========================================================== PROTEUS_MIRABILIS V-----legkda-k------------- 1H6NA_Proteus_mirabilis V-----le------------------- 1H7KA_Proteus_mirabilis V-----l-------------------- Acinetobacter_calcoaceticus L--t--venaqa-aretdparglpsfi Actinobacillus_pleuropneumoniae a-----meaynt-dpamgqpglikpnf Actinobacillus_succinogenes Mtvtdameaynt-dpalgqpglikpdf Chromobacterium_violaceum L-----sv------------------- Colwellia_psychrerythraea I-----lldti---------------- Desulfotalea_psychrophila L-----pvsele-e------------- Haemophilus_influenzae a-----lkardt-dpalgqggll---- Neisseria_gonorrhoeae L--t--vedaqavr-atdpalgqagll Nitrosomonas_europaea I----alsevd---------------- Nitrosomonas_eutropha I-----pmgevg--------------- Pasteurella_multocida L-----ak------------------- Photorhabdus_luminescens k-----ikg------------------ Pseudomonas_aeruginosa L-----kld------------------ Streptomyces_coelicolor a-----laagnl--------------- Vibrio_fischeri I------dvsef-n------------- Yersinia_pestis L-----n-------------------- =========================================================== MICROCOCCUS_LUTEUS r-----hegdgipgveaggeari---- =========================================================== HELICOBACTER_PYLORI k-----hqkmmkdmhgkdmhhtkkkk- =========================================================== ENTEROCOCCUS_FAECALIS q-----qa------------------- Bacillus_licheniformis L-----svpqev--------------- Bacillus_subtilis k-----ds------------------- Oceanobacillus_iheyensis L-----qvpesvk-------------- =========================================================== Consensus vxxxxxxxxxxxxxxxxxxxxxxxxxx