10 20 30 40 50 60 70 ----:----|----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus xxxxxieafgaxxxexxxplkpmeixrKxpgxNDIqIEIxyCGVChSDIHqvrxeWagtvfPcVpGHEIVGKVsa =================================================================================================== YEAST sypekfEgiaiqshEdwknpKktKydpKpfydHDIdIKIeaCGVCgSDIHcaaghWgnmkmPlVvGHEIVGKVvk Candida_glabrata tsedkfQgiavldhKdwknpKkVEfpaKpfydHDIdIKIeaCGVCgSDIHcaagnWgkkqtPlVvGHEIIGKVvk =================================================================================================== ECOLI ----kIKAvGAysaKq--PLEPMDItRRePGpNDVKIEIaYCGVCHSDLHQVRsEWAGTVYPCVPGHEIVGRVvA Azotobacter_vinelandii ----vVKAYGAyagDk--PLEPLEItRRpPGpHDVQIDItYCGICHSDLHQVRaEWAGTrFPCVPGHEIVGRVSA Burkholderia_fungorum ---sttyAYaAtdata--PLaPfEIqRRelraHDVQMEVlFCGVCHSDLHQaRnEWknTVFPvVPGHEIVGRVTA Erwinia_carotovora ----lVnAYGAhagDk--PLEPLKIvRRaPGaHDVQIEIaYCGICHSDLHQVRaEWAGTqFPCVPGHEIVGRVSA Nitrosomonas_europaea ----tIKAYGAragDl--PLEPMnItRRtPsaHDVQIDIthCGVCHSDLHQVRsEWAGTLYPCVPGHEIVGRITA Pseudomonas_cepacia ----tVKAYGAyagDk--aLEsMDIvRRaPGaHDVKIDIaFCGVCHSDIHQVRaEWAGTLFPCVPGHEIVGRVSA Shewanella_putrefaciens ----kIKAFGAnashl--PLEPMtItRRlPGeDDVQIsIdYCGVCHSDLHQVRsEWAGTLYPCVPGHEIVGRVTA Xanthomonas_vasicola ---skahAYaAqtaDq--PLaPfvfeRRaPGpDDVQIDIaYCGVCHSDLHtaRnEWhnTVYPsVPGHEIVGRVTA Xylella_fastidiosa ----fInAYGAhagDk--PLEsMQIaRRaPGaHDVQIDIhYCGVCHSDIHQVRsEWAGTLFPCVPGHEIVGRVSA =================================================================================================== Consensus xxxxxieafgaxxxexxxplkpmeixrKxpgxNDIqIEIxyCGVChSDIHqvrxeWagtvfPcVpGHEIVGKVsa 80 90 100 110 120 130 140 150 ----|----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus LGxxnvsxfkxGElVGVGciVdSCkxCxeCedglEnYCdxxmvgTYSxPtxexxgxSlGGYseqVvVhErFvVrI =================================================================================================== YEAST LGpkSnSglKvGQrVGVGaqVfSCleCdrCKNdnEpYCtk-fVtTYSqPy-EdgyvSqGGYanyVrVHEhFVVpI Candida_glabrata IGpkcnTglKvGDrVGVGaqVfSCleCdrCKNdnEpYCpk-fVtTYSqPy-EdgyvSqGGYanyVrVHEhFaVpI =================================================================================================== ECOLI VG-dqVekYapGDLVGVGCIVDSCKhCeECEDGLENYCDh-MtGTYNsPTpDepGhTLGGYSQQIVVHERYVLRI Azotobacter_vinelandii VG-aHVSdFRaGDLVGIGCIVDSCRhCeECDaGLENYCDg-MVGTYNfPTpDepGwTLGGYSQRIVVHEgYVLRI Burkholderia_fungorum VG-pDVTkhKvGDLVGVGCLVDSCRtCasCEEGLEqYCEngfVGTYNgvdrvdgqiTyGGYStQLVVdEeFtLsV Erwinia_carotovora VG-pHVSaFKaGDLVGIGCIVDSCRhCeECDEGLENYCDg-MVGTYNgPTaDepGwTLGGYSQQIVVHERYVLRV Nitrosomonas_europaea VG-aqVSgYKpGDLVGVGCIVDSCQhCaDCnDGLENYCDh-MVlTYNgPTsDapGhTLGGYSQQIVVHERYVLRI Pseudomonas_cepacia VG-aNVSgFKvGELVGVGCIVDSCRhCaDCDEGLENYCDh-MVGTYNgPTaDapGhTLGGYSQEIVVHERYVLRI Shewanella_putrefaciens VG-gHVSkFnvGDLVGVGCIVDSCKhChECiDdqENYCDh-MVGTYNgPThDalGhTLGGYaEQIVVdERYVLRI Xanthomonas_vasicola VG-saVTnFKvGDLaGVGCMVDSCRsCasCQEGeEqYCEqgftGTYNgPmfgggenTyGGYSDhIVVdQKYVLhI Xylella_fastidiosa IG-tHVqgFKaGDLVaVGCMVDSCKdCqECDaGLENYCDg-MIGTYNfPTqDapGhTLGGYSQKIVVHERFVLRI =================================================================================================== Consensus LGxxnvsxfkxGElVGVGciVdSCkxCxeCedglEnYCdxxmvgTYSxPtxexxgxSlGGYseqVvVhErFvVrI 160 170 180 190 200 210 220 ----:----|----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus xhxqxqlaavAPLLCaGLTtYSPLrhwxxGPGQKVGIVGLGGIGHMgLkIAnAMGAxVvafStSxsKREdAkaMG =================================================================================================== YEAST pe-nipshlaAPLLCgGLTvYSPLvrngcGPGKKVGIVGLGGIGsMGtlIskAMGAetyviSrSsrKREDAmkMG Candida_glabrata pe-nipshlaAPLLCgGLTvYSPLlrngcGPGKKVGIVGIGGIGHMGLlfAkAMGAeVyAiSrSnaKKEDslkLG =================================================================================================== ECOLI rHpQeQLAAVAPLLCAGITTYSPLRHWqaGPGKKVGVVGIGGLGHMGIKLAHAMGAhVVAFTTSeaKREaAKALG Azotobacter_vinelandii rHpEdQLAAVAPLLCAGITTYSPLRHWqaGPGKKVGIVGIGGLGHMGIKLAHAMGAhVVAFTTSaSKREDAKALG Burkholderia_fungorum pdnldp-AgVAPLLCAGITTYSPLRtWgaGPGKKVGIVGLGGLGHMGVKLAHAMGAhVVlFTTSpSKiEDAKrLG Erwinia_carotovora rHsEaELAAVAPLLCAGITTYSPLRHWnaGPGKKVGVVGIGGLGHMGIKLAHAMGAyVVAFTTSeSKREDAKALG Nitrosomonas_europaea rHsEaQLAAVAPLLCAGITTWSPLRHWkvGPGQKVGVVGIGGLGHMGIKLAHAMGAyVVAFTTSeSKREaARALG Pseudomonas_cepacia rHdEaQLAAVAPLLCAGITTYSPLRHWkvGPGhKVGIVGIGGLGHMdIKLANAMGAyVVAFTTSgSKREaAKALG Shewanella_putrefaciens sHpQeQLAAVAPLLCAGITTYSPLRHWhaGPGKKVGIVGIGGLGHMGIKLAHAMGAhVVAFTTSeSKRDaAKALG Xanthomonas_vasicola sHs-dnLAAVAPLLCAGITTYSPLaHWkvGPGQKVGVVGLGGLGHMaVKIAkAMGAtVVlFTTSeSKRaDAlrLG Xylella_fastidiosa rHpEaQLAAVAPLLCAGITTYSPLRHWnaGPGKKVGIVGIGGLGHMGIKLAHAMGAyVVAFTTSeSKRQDAKALG =================================================================================================== Consensus xhxqxqlaavAPLLCaGLTtYSPLrhwxxGPGQKVGIVGLGGIGHMgLkIAnAMGAxVvafStSxsKREdAkaMG 230 240 250 260 270 280 290 300 ----|----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus ANevIvTKDxxemxaahxxTfDxIVntvaaxxxhNlNxfxslMKrdGtItlIgapasxhpsxpevYnLixKrrsI =================================================================================================== YEAST ADhyIaTlEegDwgekyfdTFDlIVvcassltdiDfNimpkaMKvgGrIvsIsiPeqhemlslKpYgL--KavSI Candida_glabrata ADhyIaTKEepDwgekyfdTFDlIVvcassltdvDfDvmpkaMKvgGrIvsIsiPeqdetltmKpFgL--lgvSI =================================================================================================== ECOLI ADEVVnSRNadEM-AAHlkSFDfILNTVAAp--HNLDdFtTLLKRDGTMTLVGAPATpHkS-PEVFNLImKRRaI Azotobacter_vinelandii ADEVVVSRNpgEM-AAHakSFDlILNTVAAp--HDLDaFlSLLKRDGTLTLVGAPASpHPS-PDVFNLIfKRRSI Burkholderia_fungorum AHEVVISKNaaEM-eAHlnSFDfILNTVAAq--HDLNpFlNLLKRDGTMTLVGAPehdHPS-PQVFNLIfKRRrL Erwinia_carotovora ANEVVVSRNaeEM-AAHagSFDlILNTVAAp--HDLDaFlvLLKRDGaLTLVGAPASpHPS-PnVFNLImKRRTV Nitrosomonas_europaea AHEtVVSRNpdEM-ArHvgSlDfILNTVAAs--HDLDaFfaLLKRDGTMaLVGAPATpHPS-PnVFNLImKRRSL Pseudomonas_cepacia AHEVVVSRNadEM-sAHakSlDfILNTVAAp--HDLDaFfTLLKRDGTMTLVGAPASpHPS-PQVFNLImKRRSL Shewanella_putrefaciens ADEVVVSKNadEM-AkHlqSlDlIVNTVAAp--HDLDaFlSLLKRDGTMTLVGAPATnHPS-PnaFNLImKRRSL Xanthomonas_vasicola ASEVVISKDeaQM-AAqynTlDfILNTVAAp--HNLDpFlNaLKRDGaMvLVGvPehsHPS-PaVFNLVmKRRTL Xylella_fastidiosa ADEVVVSRDeerM-AAHvkSFDlILNTVAAs--HSLDpFlTLLKRDGTLTLVGAPATpHPS-PEVFNLIfKRRSI =================================================================================================== Consensus ANevIvTKDxxemxaahxxTfDxIVntvaaxxxhNlNxfxslMKrdGtItlIgapasxhpsxpevYnLixKrrsI 310 320 330 340 350 360 370 ----:----|----:----|----:----|----:----|----:----|----:----|----:----|----: Consensus AgSmLGgIxEtEQLLdfcaEhxIvxdVEmLraexxqVNEAFERMlKGDVRYRFvLdnxslxxxx ======================================================================================== YEAST sySaLGsIkElnQLLklvsEkdIkiwVEtLpvgeagVHEAFERMeKGDVRYRFtLvgydkefsd Candida_glabrata AnSaLGsIkEiEQLLklvsEkdIkiwVEtLpvgeagVkEAFERMdKGDVRYRFtLvDydkefgn ======================================================================================== ECOLI AGSMIGGIpETQEMLDFCAEHgIVaDIEMIRAD--QINEAYERMLRGDVKYRFVIDNrTLtd-- Azotobacter_vinelandii AGSMIGGIpETQEMLDFCAEHgIVaDIELIRAE--QINEAYERMLRGDIKYRFVIDSaTLag-- Burkholderia_fungorum AGSLIGGIaETQEMLDFCgEHgItsDIEVIpmQ--gINEAYERMLKsDVKYRFVIDldSLrk-- Erwinia_carotovora AGSMIGGIpETQEMLDFCAEHgIVsDIELIRAD--EINEAYERMLKGDVKYRFVIDNaTLsa-- Nitrosomonas_europaea AGSLIGGIsETQEMLDFCAKHnIVaDVEMIRiD--EINEAYERMLKGDVKYRFVIDcaSLta-- Pseudomonas_cepacia AGSMIGGIpETQEMLDFCAEHgIVsDIEMIRAD--QINDAYERMLKGDVKYRFVIDSsSLaq-- Shewanella_putrefaciens AGSMIGGIrETQEMLDFCAEHnIVsDIELIRAD--EINtAYERMLKGDVKYRFVIDNaTLar-- Xanthomonas_vasicola AGSLIGGIrQTQEMLDFCAKHnIVsDIEtIRAD--QINEAYERMLKGDVKYRFVIDmdTLakaa Xylella_fastidiosa AGSLIGGIaETQEMLDFCAEHgIVaDIELIRAD--gINEAYERMMKGDVKYRFVIDNaTLaa-- ======================================================================================== Consensus AgSmLGgIxEtEQLLdfcaEhxIvxdVEmLraexxqVNEAFERMlKGDVRYRFvLdnxslxxxx