10 20 30 40 50 60 70 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxVQAVCVLKGExxxxxxxxxxxxxxxxVQGt ================================================================================================ BOVINE -------------------a--------------------tKAVCVLKGD--g------------pVQGT HUMAN -------------------a--------------------tKAVCVLKGD--g------------pVQGi XENLA ----------------------------------------VKAVCVLaGs--g------------dVKGv 1CB4A_Bovine -------------------a--------------------tKAVCVLKGD--g------------pVQGT 1E9OA_Bovine -------------------a--------------------tsAVCVLsGD--g------------pVQGT 1E9OB_Bovine -------------------a--------------------tKAVCVLKGD--g------------pVQGT 1E9PA_Bovine -------------------a--------------------tsAVCVLsGD--g------------pVQGT 1E9PB_Bovine -------------------a--------------------tsAVCVLsGD--g------------pVQGT 3SODO_Bovine -------------------a--------------------tKAVaVLKGD--g------------pVQGT 1AZVA_Human -------------------a--------------------tKAVCVLKGD--g------------pVQGi 1FUNA_Human -------------------a--------------------tKAVaVLKGD--g------------pVQGi 1L3NA_Human -------------------a--------------------tKAVaVLKGD--g------------pVQGi 1N19A_Human -------------------a--------------------tKvVaVLKGD--g------------pVQGi 1PTZA_Human -------------------a--------------------tKAVaVLKGD--g------------pVQGi Apis_mellifera ----------------------------------------tKAVCVLQGE----------------VKGT Canis_lupus -------------------e--------------------MKAVCVLKGQ--g------------pVEGT Capra_hircus -------------------a--------------------tKAVCVLKGD--g------------pVQGT Cavia_porcellus -------------------a--------------------tKAVCVLKGD--g------------pVQGi Cebus_apella -------------------a--------------------MKAVCVLKGD--g------------pVQGT Cervus_elaphus -------------------a--------------------tKAVCVLKGD--g------------pVQGT Chelonia_mydas ----------------a--t--------------------VKAVCVLKGE--dpvkepvkgpvkepVKGi Danio_rerio -------------------v--------------------nKAVCVLKGt--g------------eVtGT Equus_caballus -------------------a--------------------LKAVCVLKGD--g------------pVhGv Gallus_gallus ----------------a--t--------------------LKAVCVMKGD--a------------pVEGv Hylobates_lar -------------------a--------------------MKAVCVLKGD--s------------pVQGi Macaca_mulatta -------------------a--------------------MKAVCVLKGD--s------------pVQGT Mus_musculus -------------------a--------------------MKAVCVLKGD--g------------pVQGT Oncorhynchus_mykiss -------------------a--------------------MKAVCVLKGt--g------------eVtGT Oryctolagus_cuniculus -------------------a--------------------tKAVCVLKGD--g------------pVEaT Ovis_aries -------------------a--------------------tKAVCVLKGD--g------------pVQGT Pongo_pygmaeus -------------------a--------------------tKAVCVLKGD-ns------------pVKGi Rattus_norvegicus -------------------a--------------------MKAVCVLKGD--g------------pVQGv Sus_scrofa -------------------a--------------------tKAVCVLKGD--g------------pVQGT Tetraodon_nigroviridis pasavlpcvsflevttakmv--------------------IKAVCVLKGa--g------------etsGT Xenopus_tropicalis ----------------------------------------VRAVCVLaGs--g------------dVKGv ================================================================================================ SCHISTOSOMA_MANSONI -----------------gsn--------------------MKAVCVMtGt--a------------gVKGv Schistosoma_japonicum -----------------------------------------KAVCVMsGs--a------------gVKGv ================================================================================================ YEAST ----------------------------------------VQAVaVLKGD--a------------gVsGv 1B4TA_Yeast ----------------------------------------VQAVaVLKGD--a------------gVsGv 1F18A_Yeast ----------------------------------------VQAVaVLKGD--a------------gVsGv 1F1AA_Yeast ----------------------------------------VQAVaVLKGD--a------------gVsGv 1F1DA_Yeast ----------------------------------------VQAVaVLKGD--a------------gVsGv 1JK9C_Yeast ----------------------------------------VQAVaVLKGD--a------------gVsGv Aspergillus_flavus ----------------------------------------VKAVaVLRGD--s------------kIsGT Aspergillus_fumigatus ----------------------------------------VKAVaVLRGD--s------------kItGT Candida_albicans ----------------------------------------VKAVaVVRGD--s------------kVQGT Candida_glabrata ----------------------------------------VKAVaVLRGs--a------------gVsGv Cryptococcus_neoformans ----------------------------------------VKAVaVLKGD--s------------yVhGT Debaryomyces_hansenii ----------------------------------------aKAVaVLRGD--s------------kVsGv Emericella_nidulans ----------------------------------------VKAVaVLRGD--s------------kVsGT Eremothecium_gossypii vkaskywrwwlggngsilt---------------------VKAVaVLKGD--a------------gVsGv Gibberella_zeae iklth-----------------------------------slAVsVLRGD--s------------kVsGT Kluyveromyces_lactis ----------------------------------------VnAVaVLKGD--s------------sVsGi Neurospora_crassa ----------------------------------------VKAVaVVRGD--s------------nVKGT Schizosaccharomyces_pombe ----------------------------------------VRAVaVLRGD--s------------kVsGv Yarrowia_lipolytica ----------------------------------------VKAVaVLRGD--s------------kVsGT ================================================================================================ PHOTOBACTERIUM_LEIOGNATHI -------------------nkaktllftalafglshqalaqdltvkMtdlqtg------------kpvGT Vibrio_splendidus ---------------------nkttwlaalal-isspvfaevvnveMidlgsg------------qstGT ================================================================================================ Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxVQAVCVLKGExxxxxxxxxxxxxxxxVQGt