10 20 30 40 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx =============================================================================== PYROCOCCUS_FURIOSUS -------------------------------age----evke--- Pyrococcus_abyssi ------------------------mimgkkssdp----avve--- =============================================================================== METHANOCOCCUS_VOLTAE -------------------------------sdn----------- Methanococcus_jannaschii itfiyffgniiyylpiysyinnykfmlmviimdd----------- =============================================================================== SULFOLOBUS_SOLFATARICUS ----------------------------------sne----veqk Aeropyrum_pernix -----------------------------------------gedk Desulfurococcus_amylolyticus ----------------------------------seeketikers Sulfolobus_tokodaii ----------------------------------ndm----ssdg =============================================================================== HUMAN --------------------------------------------- YEAST ----------------------------------sqv-------- Apis_mellifera --------------------------------------------- Aspergillus_fumigatus --------------------------------------------- Bombyx_mandarina --------------------------------------------- Bos_taurus --------------------------------------------- Caenorhabditis_elegans -------------saqasrqkk--sdqeqra-------------- Candida_albicans ----------------------tqteie-qv---dlh-eeg---- Candida_glabrata ----------------------------------tev-------- Canis_lupus --------------------------------------------- Coprinus_cinereus --------------------------------------------- Cricetulus_griseus --------------------------------------------- Cryptococcus_neoformans --------------------------------------------- Danio_rerio --------------------------------------------- Debaryomyces_hansenii ---------------tet--------------------------- Drosophila_melanogaster --------------------------------------------- Drosophila_pseudoobscura --------------------------------------------- Emericella_nidulans --------------------------------------------- Encephalitozoon_cuniculi --------------------------------------------- Eremothecium_gossypii -sqvqehiiqdphssqynihatgaserqgss---eht-dgd---- Gallus_gallus --------------------------------------------- Gibberella_zeae --------------------------------------------- Kluyveromyces_lactis --------------------------------------------- Mus_musculus --------------------------------------------- Neurospora_crassa --------------sn----------------------------- Nosema_bombycis --------------------------------------------- Oikopleura_dioica ----------------------------------s---------- Oryctolagus_cuniculus --------------------------------------------- Pichia_angusta ---------------tqvaevnhitsneqqg---s---------- Pleurotus_ostreatus --------------------------------------------- Rattus_norvegicus --------------------------------------------- Schizosaccharomyces_pombe ------------adtevemqvsaadtnnnen---gqa-------- Strongylocentrotus_purpuratus --------------------------------------------- Tetraodon_nigroviridis --------------------------------------------- Ustilago_maydis --------------------------------------------- Xenopus_laevis --------------------------------------------- Xenopus_tropicalis --------------------------------------------- Yarrowia_lipolytica --------------------------------------------- Cryptosporidium_spp --------------stin--------------------------- Dictyostelium_discoideum -------------asrqrqe------------------------- Entamoeba_histolytica ---------sakqiqrgseeelleseenlke---ke--------- Leishmania_donovani qtrskakgrrgrpsarpsdevevvesqpqea---lqn-eeq---- Leishmania_tropica qtrskakgrrgrpsarpseevevvesqpqev---lqn-eeq---- Plasmodium_berghei --------------ksan--------------------------- Plasmodium_falciparum --------------------------------------------- Plasmodium_yoelii ---------pamksanaked------------------------- Tetrahymena_thermophila --------------------------------------------- Theileria_annulata -------------------------ssd----------------- Theileria_parva -------------------------ssd----------------- Trypanosoma_brucei ------------ntrtknkkrtkeviedevh---did-dta---- Trypanosoma_cruzi -------ntrskrgkrkgveevevheiants---pdp-vaa---- Arabidopsis_thaliana --------------------------------------------- Oryza_sativa --------------------------------------------- Zea_mays --------------------------------------------- =============================================================================== ECOLI ----------------------------------ai--------- MYCOBACTERIUM_SMEGMATIS ----------------------------------aqq-------- MYCOBACTERIUM_TUBERCULOSIS ----------------------------------tq--------- Acetobacter_polyoxogenes -----------------aq---------------ap--------- Acinetobacter_calcoaceticus --------------------------------------------- Actinobacillus_pleuropneumoniae -----------------asdnkkaqkntvtk---qi--------- Actinobacillus_succinogenes -----------------atpndktk---------ps--------- Bacillus_licheniformis --------------------------------------------- Bacillus_subtilis --------------------------------------------- Burkholderia_fungorum -----------------eeskkgsa---------gl--------- Carboxydothermus_hydrogenoformans --------------------------------------------- Chromobacterium_violaceum -----------------------------------a--------- Clostridium_thermocellum --------------------------------------------- Colwellia_psychrerythraea --------------------------------------------- Desulfotalea_psychrophila -----------------v----------------gat-------- Enterococcus_faecalis --------------------------------------------- Erwinia_carotovora -----------------------------------ai-------- Haemophilus_ducreyi -----------------aadkkaqkntatk----qi--------- Haemophilus_influenzae ----------------------------------at--------- Histophilus_somni ----------------------------------at--------- Kineococcus_radiotolerans ----------------------------------pa--------- Leifsonia_xyli -----------------------------------ps-------- Listeria_monocytogenes --------------------------------------------- Mannheimia_succiniciproducens ----------------------------------at--------- Neisseria_gonorrhoeae --------------------------------------------- Nitrosomonas_europaea --------------------------------------------- Nitrosomonas_eutropha --------------------------------------------- Oceanobacillus_iheyensis --------------------------------------------- Pasteurella_multocida --------------------------------------------- Photobacterium_profundum --------------------------------------------- Photorhabdus_luminescens ----------------------------------ai--------- Proteus_mirabilis ----------------------------------ai--------- Pseudomonas_aeruginosa --------------------------------------------- Pseudomonas_cepacia --------------------------------------------- Salmonella_typhi ----------------------------------ai--------- Shewanella_putrefaciens -----------------------------------kv-------- Streptomyces_avermitilis -----------------------------------a--------- Streptomyces_coelicolor -----------------------------------a--------- Streptomyces_lividans -----------------------------------a--------- Vibrio_cholerae --------------------------------------------- Vibrio_splendidus --------------------------------------------- Vibrio_vulnificus --------------------------------------------- Xanthomonas_vasicola --------------------------------------------- Xylella_fastidiosa --------------------------------------------- Yersinia_pestis ----------------------------------ai--------- =============================================================================== DEINOCOCCUS_RADIODURANS ----------------------------------gsh-------- Deinococcus_geothermalis --------------------------------------------- Thermus_aquaticus --------------------------------------------- =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx