550 560 570 580 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxixxxxxsxr =============================================================================== PYROCOCCUS_FURIOSUS aphlp-egeavfsit-ekgied----------------------- Pyrococcus_abyssi aphlp-egeavfrit-ekgied----------------------- =============================================================================== METHANOCOCCUS_VOLTAE aklydsphlp-daeaifrit-ekgiqd------------------ Methanococcus_jannaschii aklydsphlp-daeamfrit-ekgihd------------------ =============================================================================== SULFOLOBUS_SOLFATARICUS vvdaphlp-egevvfalt-eegird--ae---------------- Aeropyrum_pernix vvdaphlp-egetvfait-ewgird--pe---------------- Desulfurococcus_amylolyticus vvdaphlp-egevvfvit-eegird--se---------------- Sulfolobus_tokodaii ivdaphlp-egevvfait-eegvrd--ae---------------- =============================================================================== HUMAN ---------------------m--faadpkkpiggnIiahasTtR YEAST ---------------------a--fnpdpkkptggnImahssTtR Apis_mellifera ---------------------s-mfggdqkkpigghIiahasTtR Aspergillus_fumigatus ---------------------m--fnpdpkkpiggnIiahasTtR Bombyx_mandarina ---------------------v--fnadtkkpigghIiahasTtR Bos_taurus ---------------------m--faadpkkpiggnIiahasTtR Caenorhabditis_elegans ---------------------m--fqadakkpigghIiahmsTtR Candida_albicans ---------------------m--fnpdpkkpiggnIiahssTtR Candida_glabrata ---------------------s--fnpdpkkpiggnImahssTtR Canis_lupus ---------------------m--faadpkkpiggnIiahasTtR Coprinus_cinereus ---------------------p--yagnekkpiggnImahasTtR Cricetulus_griseus ---------------------m--ftadpkkpiggnIiahasTtR Cryptococcus_neoformans ---------------------f--avadakkpiggnImahasTtR Danio_rerio ---------------------m--fsadpkkpiggnIlahasTtR Debaryomyces_hansenii ---------------------m--fnpdpkkpiggnIiahssTtR Drosophila_melanogaster ---------------------g--mf-dakkpigghImahssTtR Drosophila_pseudoobscura ---------------------m--fvadakkpvgghIlahasTtR Emericella_nidulans ---------------------m--fnpdpkkpiggnIiahasTtR Encephalitozoon_cuniculi ---------------------m--ftgdikkpiggnImahasTtR Eremothecium_gossypii ---------------------m--fnpdpkkpiggnImahssTtR Gallus_gallus ---------------------m--faadpkkpiggnIiahasTtR Gibberella_zeae ---------------------m--fnpdpkkpiggnIiahasTtR Kluyveromyces_lactis ---------------------m--fnpdpkkpiggnImahssTtR Mus_musculus ---------------------m--faadpkkpiggnIiahasTtR Neurospora_crassa ---------------------m--fnpdpkkpiggnIiahasTtR Nosema_bombycis ---------------------m--fagdvkkpiggnImahasTtR Oikopleura_dioica ---------------------m--mmgdnqtpvggnIlahasctR Oryctolagus_cuniculus ---------------------m--faadpkkpiggnIiahasTtR Pichia_angusta ---------------------i--fnpdpkkpiggnIvahssTtR Pleurotus_ostreatus ---------------------gp-yagnekkpiggnImahasTtR Rattus_norvegicus ---------------------m--faadpkkpiggnIiahasTtR Schizosaccharomyces_pombe ------------------------fnpdpkkpiggnIlahssTtR Strongylocentrotus_purpuratus ---------------------m--ftsdpkkpigghImahasTtR Tetraodon_nigroviridis ---------------------k--tcgygiteetsefvqlvlfav Ustilago_maydis ---------------------a--ftadakkpiggnIvahasTtR Xenopus_laevis ---------------------m--faadpkkpiggnIiahasTtR Xenopus_tropicalis ---------------------m--faadpkkpiggnIiahasTtR Yarrowia_lipolytica ------------------------fnpdpkkpiggnIvahasTtR Cryptosporidium_spp ---------------------a--mfqndkvpiggnIiahasqtR Dictyostelium_discoideum ---------------------m--fnpdpkkpigghImahssTtR Entamoeba_histolytica ---------------------m--fggdtkkpvggnIiahasTtR Leishmania_donovani ---------------------m--fqadskkpigghImahasTtR Leishmania_tropica ----------------q----m--fqadskkpigghImahasTtR Plasmodium_berghei ---------------------m--fgghekipiggnIiahasqtR Plasmodium_falciparum ---------------------m--fgghekipiggnIiahasqtR Plasmodium_yoelii ---------------------m--fgghekipiggnIiahasqtR Tetrahymena_thermophila ---------------------m--fagdmkkpiggnImahasTtR Theileria_annulata lllyiiiycyilinickfyidk--fvgndklpvgghIiahasqtR Theileria_parva ---------------------t--ffgndklpvgghIiahasqtR Trypanosoma_brucei ---------------------t--fqadskkpigghImahasTtR Trypanosoma_cruzi ----------------q----m--fqadakkpigghImahasTtR Arabidopsis_thaliana ---------------------l--fagpqfkpiggnImahatTtR Oryza_sativa ---------------------m--fagpqikpiggnImahasTtR Zea_mays ---------------------m--fagpqikpiggnImahasTtR =============================================================================== ECOLI ggnalkfya---------------------------------SvR MYCOBACTERIUM_SMEGMATIS ggkalkfya---------------------------------SvR MYCOBACTERIUM_TUBERCULOSIS ggkalkfya---------------------------------SvR Acetobacter_polyoxogenes ggnalkfya---------------------------------SvR Acinetobacter_calcoaceticus ggnalkfya---------------------------------SvR Actinobacillus_pleuropneumoniae ggnalkfya---------------------------------SvR Actinobacillus_succinogenes ggnalkfys---------------------------------SvR Bacillus_licheniformis ggralkfys---------------------------------SvR Bacillus_subtilis ggralkfys---------------------------------SvR Burkholderia_fungorum ggnalkfya---------------------------------SvR Carboxydothermus_hydrogenoformans ggralkfya---------------------------------SiR Chromobacterium_violaceum ggnalkfya---------------------------------SvR Clostridium_thermocellum ggralkfya---------------------------------SvR Colwellia_psychrerythraea ggnalkfya---------------------------------SvR Desulfotalea_psychrophila ggnalkfyc---------------------------------SeR Enterococcus_faecalis ggralkfya---------------------------------TvR Erwinia_carotovora ggnalkfya---------------------------------SvR Haemophilus_ducreyi ggnalkfya---------------------------------SvR Haemophilus_influenzae ggnalkfys---------------------------------SvR Histophilus_somni ggnalkfya---------------------------------SvR Kineococcus_radiotolerans ggkalkfya---------------------------------SvR Leifsonia_xyli ggkalkfya---------------------------------SvR Listeria_monocytogenes ggralkfys---------------------------------TvR Mannheimia_succiniciproducens ggnalkfys---------------------------------SvR Neisseria_gonorrhoeae ggnalkfys---------------------------------SvR Nitrosomonas_europaea ggnalkfya---------------------------------SvR Nitrosomonas_eutropha ggnalkfya---------------------------------SvR Oceanobacillus_iheyensis ggralkfys---------------------------------SvR Pasteurella_multocida ggnalkfya---------------------------------SvR Photobacterium_profundum ggnalkfya---------------------------------SvR Photorhabdus_luminescens ggnalkfya---------------------------------SvR Proteus_mirabilis ggnalkfya---------------------------------SvR Pseudomonas_aeruginosa ggnalkfya---------------------------------SvR Pseudomonas_cepacia ggnalkfys---------------------------------SvR Salmonella_typhi ggnalkfya---------------------------------SvR Shewanella_putrefaciens ggnalkfya---------------------------------SvR Streptomyces_avermitilis ggralkfya---------------------------------SvR Streptomyces_coelicolor ggralkfya---------------------------------SvR Streptomyces_lividans ggralkfya---------------------------------SvR Vibrio_cholerae ggnalkfya---------------------------------SvR Vibrio_splendidus ggnalkfya---------------------------------SvR Vibrio_vulnificus ggnalkfya---------------------------------SvR Xanthomonas_vasicola ggnalkfya---------------------------------SvR Xylella_fastidiosa ggnalkfya---------------------------------SvR Yersinia_pestis ggnalkfya---------------------------------SvR =============================================================================== DEINOCOCCUS_RADIODURANS --kiktvknkvaapfkevelalvygkgfdq-lsd-lVglaadmdi Deinococcus_geothermalis --kvktvknkvappfkeveltllygkgfdq-lsd-lVtlaadmdi Thermus_aquaticus --kvkvvknklappfreaeleiyfgrgldp-vmd-lVnvavaagv =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxixxxxxsxr