100 110 120 130 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx =============================================================================== PYROCOCCUS_FURIOSUS kkkkekiir--siedlpgv--------g-pat--------a--ek Pyrococcus_abyssi kkkkekeir--tiedlpgv--------g-pat--------a--ek =============================================================================== METHANOCOCCUS_VOLTAE -------------l--tdlpgvgp-----s----tae-----k-- Methanococcus_jannaschii -------------l--tqlpgvgp-----t----tae-----k-- =============================================================================== SULFOLOBUS_SOLFATARICUS -----------n--iktindlp------g---isq------t--- Aeropyrum_pernix -----------e--ikditdlp------g---vgp------t--- Desulfurococcus_amylolyticus -----------g--fisvrdip------g---vgs------s--- Sulfolobus_tokodaii -----------k--vkslsdlp------g---vgq------s--- =============================================================================== HUMAN --------------------a------------------------ YEAST edieatngsgdgg-------g------------------------ Apis_mellifera ------------s-------a------------------------ Aspergillus_fumigatus --------------------t------------------------ Bombyx_mandarina --------------------------------------------- Bos_taurus --------------------------------------------- Caenorhabditis_elegans --------------------a------------------------ Candida_albicans --------------------s------------------------ Candida_glabrata ----stnrsmdynsge----q------------------------ Canis_lupus --------------------a------------------------ Coprinus_cinereus --------------------s------------------------ Cricetulus_griseus --------------------a------------------------ Cryptococcus_neoformans -----sreqeqdp-------f------------------------ Danio_rerio --------------------------------------------- Debaryomyces_hansenii --------------------e------------------------ Drosophila_melanogaster --------------------------------------------- Drosophila_pseudoobscura --------------------------------------------- Emericella_nidulans --------------------t------------------------ Encephalitozoon_cuniculi --------------------s------------------------ Eremothecium_gossypii --------------------v------------------------ Gallus_gallus --------------------a------------------------ Gibberella_zeae --------------------s------------------------ Kluyveromyces_lactis eqme----------------d------------------------ Mus_musculus --------------------a------------------------ Neurospora_crassa --------------------n------------------------ Nosema_bombycis --------------------------------------------- Oikopleura_dioica --------------------a------------------------ Oryctolagus_cuniculus --------------------a------------------------ Pichia_angusta --------------------v------------------------ Pleurotus_ostreatus --------------------------------------------- Rattus_norvegicus --------------------a------------------------ Schizosaccharomyces_pombe --------------------q------------------------ Strongylocentrotus_purpuratus --------------------a------------------------ Tetraodon_nigroviridis --------------------a------------------------ Ustilago_maydis --------------------s------------------------ Xenopus_laevis --------------------a------------------------ Xenopus_tropicalis --------------------a------------------------ Yarrowia_lipolytica --------------------------------------------- Cryptosporidium_spp --------------------p------------------------ Dictyostelium_discoideum --------------------e------------------------ Entamoeba_histolytica --------------------k------------------------ Leishmania_donovani --------------------e------------------------ Leishmania_tropica --------------------e------------------------ Plasmodium_berghei --------------------a------------------------ Plasmodium_falciparum ---kqantkedks-------q------------------------ Plasmodium_yoelii --------------------t------------------------ Tetrahymena_thermophila --------------------------------------------- Theileria_annulata --------------------e------------------------ Theileria_parva --------------------e------------------------ Trypanosoma_brucei --------------------f------------------------ Trypanosoma_cruzi --------------------p------------------------ Arabidopsis_thaliana --------------------t------------------------ Oryza_sativa --------------------s------------------------ Zea_mays ------------s-------s------------------------ =============================================================================== ECOLI --------------------d------------------------ MYCOBACTERIUM_SMEGMATIS --------------------a------------------------ MYCOBACTERIUM_TUBERCULOSIS --------------------a------------------------ Acetobacter_polyoxogenes --------------------g------------------------ Acinetobacter_calcoaceticus --------------------d------------------------ Actinobacillus_pleuropneumoniae --------------------dp----------------------- Actinobacillus_succinogenes --------------------a------------------------ Bacillus_licheniformis --------------------------------------------- Bacillus_subtilis --------------------------------------------- Burkholderia_fungorum --------------------t------------------------ Carboxydothermus_hydrogenoformans --------------------------------------------- Chromobacterium_violaceum --------------------s------------------------ Clostridium_thermocellum --------------------------------------------- Colwellia_psychrerythraea --------------------k------------------------ Desulfotalea_psychrophila --------------------a------------------------ Enterococcus_faecalis --------------------a------------------------ Erwinia_carotovora --------------------d------------------------ Haemophilus_ducreyi --------------------dp----------------------- Haemophilus_influenzae --------------------q------------------------ Histophilus_somni --------------------p------------------------ Kineococcus_radiotolerans --------------------p------------------------ Leifsonia_xyli --------------------p------------------------ Listeria_monocytogenes --------------------------------------------- Mannheimia_succiniciproducens --------------------n------------------------ Neisseria_gonorrhoeae --------------------s------------------------ Nitrosomonas_europaea --------------------d------------------------ Nitrosomonas_eutropha --------------------d------------------------ Oceanobacillus_iheyensis --------------------------------------------- Pasteurella_multocida --------------------d------------------------ Photobacterium_profundum --------------------d------------------------ Photorhabdus_luminescens --------------------d------------------------ Proteus_mirabilis --------------------d------------------------ Pseudomonas_aeruginosa --------------------d------------------------ Pseudomonas_cepacia --------------------t------------------------ Salmonella_typhi --------------------d------------------------ Shewanella_putrefaciens --------------------d------------------------ Streptomyces_avermitilis --------------------g------------------------ Streptomyces_coelicolor --------------------g------------------------ Streptomyces_lividans --------------------g------------------------ Vibrio_cholerae --------------------d------------------------ Vibrio_splendidus --------------------------------------------- Vibrio_vulnificus --------------------d------------------------ Xanthomonas_vasicola --------------------d------------------------ Xylella_fastidiosa --------------------d------------------------ Yersinia_pestis --------------------d------------------------ =============================================================================== DEINOCOCCUS_RADIODURANS ----------------a--kerskaie-----t----ams----q Deinococcus_geothermalis ----------------s--kerlkaie-----t----amt----q Thermus_aquaticus ----------------e--enkrksle-----n----alk----t =============================================================================== Consensus xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx