230 240 250 260 270 ----|----:----|----:----|----:----|----:----| Consensus lxxmxxxxxxxxxxnlxxlxxxxxxxxqxvxxxxxxxlxxxxxxx =============================================================================== PYROCOCCUS_FURIOSUS atigristgsksldkLl-gggietqaiteVf-------------- Pyrococcus_abyssi esigristgsksldkLl-gggietqaiteVf-------------- =============================================================================== METHANOCOCCUS_VOLTAE LlkqrstvwklstsSseldsvl-ggglEsqsvtefa--------- Methanococcus_jannaschii VlsqrkniwklstgSknldeil-ggglEsqsvtefa--------- =============================================================================== SULFOLOBUS_SOLFATARICUS kerMnvkkistgsqaLdgLl-aggietRtMteff----------- Aeropyrum_pernix IesMnikkittgsrNLdeLl-gggietKtItelf----------- Desulfurococcus_amylolyticus qersnigkittgskSLdeLl-gggvetKtIteff----------- Sulfolobus_tokodaii kerIntkkittgsqaLdgLl-gggietRtMtelf----------- =============================================================================== HUMAN IsrL-e-qcginanDVkkLeeagfhtvEaVayapkkeLinikgis YEAST IekL-q-vngitmaDVkkLresglhtaEaVayaprkdLleikgis Apis_mellifera IktL-e-gngitagDVkkLeeagyytvEaVayapkkcLiaikgis Aspergillus_fumigatus LsaL-egvagltsrDIklfvdagyhtvEsIaytpkrlLeqikgis Bombyx_mandarina IskL-e-gngitsgDIkkLeeagyhtvEsVayapkkwLitikgis Bos_taurus --------------------------------------------- Caenorhabditis_elegans IdkL-e-ssgissgDIskLkeagyytyEsLafttrreLrnvkgis Candida_albicans IeqL-e-gnginasDIkkLkaegfhtiEsIaytpkrhLmtvkgis Candida_glabrata LekL-q-vngitstDIkkLresglhtvEaVayapkkdLleikgis Canis_lupus IsrL-e-qcginanDVkkLeeagfhtvEaVayapkkeLisikgis Coprinus_cinereus VnkL-q-eagihanDIkkLadaglntvEaVaftpkknLlairgis Cricetulus_griseus IsrL-e-qcgisanDVkkLeeagfhtvEaVayapkkeLinikgis Cryptococcus_neoformans VakL-q-eagisaqDtkkLadagfhtvEaVaftpkktLctikgis Danio_rerio VsrL-e-qsgisssDIkkLedggfhtvEaVayapkkeLlnikgis Debaryomyces_hansenii IeqL-e-gngitsgDIrkLkaegyhtiEsIaytpkkaLllvkgis Drosophila_melanogaster VtkL-i-ggsitakDIklLqqaslhtvEsVanatkkqLmaipglg Drosophila_pseudoobscura VtkL-i-ggsitakDIklLqqaslhtvdaVanatrkhLlaipglg Emericella_nidulans LssL-egmagltsrDIklfvdagyhtvEsIaytpkrlLeqikgis Encephalitozoon_cuniculi IseL-k-nggilavDIakLieagfttvEsLafapkrqLlsikgfs Eremothecium_gossypii LerL-q-vngitnnDLkkLrenglhtvEaVayaprkdLleikgis Gallus_gallus IsrL-e-qcginanDVkkLeeagyhtvEsVahapkkeLlnikgis Gibberella_zeae LfaL-egvagltkrDIqlVvdggyntvEsVaytprrvLeqikgis Kluyveromyces_lactis IekL-q-vngitsgDIkkLresglhtaEaVayaprkdLmeikgis Mus_musculus IsrL-e-qcginanDVkkLeeagyhtvEaVayapkkeLinikgis Neurospora_crassa LsaL-egvagltkrDIqlIvdggfntvEsVaytprrvLeqikgis Nosema_bombycis LevL-k-nqgigpaDInkLieagynsvEaLayapkkqLltikgfs Oikopleura_dioica dklL-c-q-giiksDLnkLktaglhtaEqVsmctkkdLcaikgfs Oryctolagus_cuniculus VsrL-e-qcginanDVkkLeeagfhteEaVayapkkeLinikgis Pichia_angusta IqqL-v-gngitpqDIkkLkeagfhtvEsIaytpkrhIvtvkgis Pleurotus_ostreatus IskL-q-eagihanDIkkLsdaglntxEsVaftpkkaLiaikgis Rattus_norvegicus IsrL-e-qcginanDVkkLeeagyhtvEaVayapkkeLinikgis Schizosaccharomyces_pombe LqmL-e-gngitasDIkkIheagyytvEsIaytpkrqLllikgis Strongylocentrotus_purpuratus IsrL-e-asgissnDVkkLeeagmhtvEsVaystkkeLcavkgis Tetraodon_nigroviridis LcrL-e-qcgisasDIkkLedagfhtiEaVayapkkeLlnikgis Ustilago_maydis VskL-e-efgisssDckkLaesgyntvEsIaftpkkqLllvkgvs Xenopus_laevis IsrL-e-qcginanDVkkLeeagfhtvEaVayapkkeLlnikgis Xenopus_tropicalis IsrL-e-qcginanDVkkLeeagfhtvEaVayapkkeLinikgis Yarrowia_lipolytica IerL-a-vngitqtDInrLgefglytvEsVaytpkkhLltikgis Cryptosporidium_spp LehL-l-psgltkrDLeiLrengyhtiEcLayapkkaLlsvkgis Dictyostelium_discoideum InkL-e-gnginaaDLkkLqeqglntvQaVafttkktLtgikgis Entamoeba_histolytica IrkLig-lagitegDckkLeeagfftvQsIaftpkkqLitikgis Leishmania_donovani IqiL-e-nygvassDIkkLmecgfytvEsaayapkkaIlavkgis Leishmania_tropica IqiL-e-nygvassDIkkLmecgfytvEsaayapkkaIlavkgis Plasmodium_berghei IeqL-l-akgfvkrDLelLkegglqtvEcVayapmrtLcsikgis Plasmodium_falciparum IeqL-l-akgfvkrDLelLkegglqtvEcVayapmrtLcaikgis Plasmodium_yoelii IeqL-l-akgfvkrDLelLkegglqtvEcVayapmrtLcsikgis Tetrahymena_thermophila IakL-e-ehginnaDVkkLidagfqtvEsIsytakknLlqikgmt Theileria_annulata LecL-l-skgllqrDLdlLreagystlEcVayapqknLlvikgls Theileria_parva LecL-l-skgllqrDLdlLreagystlEcVayapqknLlvikgls Trypanosoma_brucei LqiM-e-nygvasaDIkkLmecgfltvEsVayapkksIlavkgis Trypanosoma_cruzi IqvL-e-sygiasaDIkkLmesgfytvEsVayapkknIlavkgis Arabidopsis_thaliana VeqL-q-aagiasvDVkkLrdaglctvEgVaytprkdLlqikgis Oryza_sativa IeqL-q-asgiaalDVkkLkdsglytvEsVaytprkdLlqikgis Zea_mays IeqL-q-asgiaalDVkkLkdsglhtvEaVaysprkdLlqikgis =============================================================================== ECOLI --------------------------------------------- MYCOBACTERIUM_SMEGMATIS --------------------------------------------- MYCOBACTERIUM_TUBERCULOSIS --------------------------------------------- Acetobacter_polyoxogenes --------------------------------------------- Acinetobacter_calcoaceticus --------------------------------------------- Actinobacillus_pleuropneumoniae --------------------------------------------- Actinobacillus_succinogenes --------------------------------------------- Bacillus_licheniformis --------------------------------------------- Bacillus_subtilis --------------------------------------------- Burkholderia_fungorum --------------------------------------------- Carboxydothermus_hydrogenoformans --------------------------------------------- Chromobacterium_violaceum --------------------------------------------- Clostridium_thermocellum --------------------------------------------- Colwellia_psychrerythraea --------------------------------------------- Desulfotalea_psychrophila --------------------------------------------- Enterococcus_faecalis --------------------------------------------- Erwinia_carotovora --------------------------------------------- Haemophilus_ducreyi --------------------------------------------- Haemophilus_influenzae --------------------------------------------- Histophilus_somni --------------------------------------------- Kineococcus_radiotolerans --------------------------------------------- Leifsonia_xyli --------------------------------------------- Listeria_monocytogenes --------------------------------------------- Mannheimia_succiniciproducens --------------------------------------------- Neisseria_gonorrhoeae --------------------------------------------- Nitrosomonas_europaea --------------------------------------------- Nitrosomonas_eutropha --------------------------------------------- Oceanobacillus_iheyensis --------------------------------------------- Pasteurella_multocida --------------------------------------------- Photobacterium_profundum --------------------------------------------- Photorhabdus_luminescens --------------------------------------------- Proteus_mirabilis --------------------------------------------- Pseudomonas_aeruginosa --------------------------------------------- Pseudomonas_cepacia --------------------------------------------- Salmonella_typhi --------------------------------------------- Shewanella_putrefaciens --------------------------------------------- Streptomyces_avermitilis --------------------------------------------- Streptomyces_coelicolor --------------------------------------------- Streptomyces_lividans --------------------------------------------- Vibrio_cholerae --------------------------------------------- Vibrio_splendidus --------------------------------------------- Vibrio_vulnificus --------------------------------------------- Xanthomonas_vasicola --------------------------------------------- Xylella_fastidiosa --------------------------------------------- Yersinia_pestis --------------------------------------------- =============================================================================== DEINOCOCCUS_RADIODURANS MklgaeskldvqvvStgsLsldlalgvggIprgriteIy------ Deinococcus_geothermalis MrlgaeskldvqavStgsLsldlalgvggIprgriteIy------ Thermus_aquaticus MrlgempklqvdviptgsLgldlalgiggIprgrvteIf------ =============================================================================== Consensus lxxmxxxxxxxxxxnlxxlxxxxxxxxqxvxxxxxxxlxxxxxxx