370 380 390 400 ----:----|----:----|----:----|----:----|----: Consensus lxiscQlxxxxxgxxxxxxxxxxxxxxgqxxfINxExxxxpxrxx =============================================================================== PYROCOCCUS_FURIOSUS rafNsnhqmllvqqaedk-ikellntdrpvklLivDsltshfRse Pyrococcus_abyssi rafNsnhqmllvqqaedk-ikellntdkpvklLivDsltshfRse =============================================================================== METHANOCOCCUS_VOLTAE ntfvaRaynsdmqmlfaekiedliqeg-----nNiKlvvidslts Methanococcus_jannaschii nifvaRaynsdmqmlyaenvenlireg-----hNiKlvivdslts =============================================================================== SULFOLOBUS_SOLFATARICUS yyIraintdhqiaivddlqel-vsk----dpsIklivvdsvtshf Aeropyrum_pernix ywIrainshhqiaivdklftm-vkn----d-nIklvvvdsvtshf Desulfurococcus_amylolyticus yyMraynsdhqiaivdelftf-vpk----n-dVrlvildsvtshf Sulfolobus_tokodaii yyMrainsdhqmaivddlqel-isk----dpaIklvivdsvtshf =============================================================================== HUMAN LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll YEAST LaVTCQIpldigG------------geGKclYIDtEgtfrPvRlv Apis_mellifera LaVNCQLpidmgG------------aeGKclYIDtEgtfrPeRli Aspergillus_fumigatus LaVTCQLpfdmgG------------geGKclYIDtEgtfrPvRll Bombyx_mandarina LaVTCQLpieqsG------------geGKcmYIDtEgtfrPeRll Bos_taurus LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Caenorhabditis_elegans LaVlCQLpidmgG------------geGKcmYIDtnatfrPeRii Candida_albicans LaVTCQLpidmgG------------geGKclYIDtEgtfrPnRlv Candida_glabrata LaVTCQIpldlgG------------geGKclYIDtEgtfrPvRlv Canis_lupus LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Coprinus_cinereus LaVTCQLpvsmgG------------geGKclYIDtEgtfrPvRll Cricetulus_griseus LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Cryptococcus_neoformans LaVTCQLpvsmgG------------geGKclYIDtEgtfrPvRml Danio_rerio LaVTCQLpidqgG------------geGKamYIDtEgtfrPeRll Debaryomyces_hansenii LaVTCQLpidmgG------------geGKclYIDtEgtfrPvRlv Drosophila_melanogaster LaVTCQLpisqkG------------geGKcmYIDtEntfrPeRla Drosophila_pseudoobscura LaVTCQLpisqkG------------geGKclYIDtEstfrteRls Emericella_nidulans LaVTCQLpfdmgG------------geGKclYIDtEgtfrPvRll Encephalitozoon_cuniculi VaVTCQLppeqgG------------ggGKamYIDtEgtfrseRlv Eremothecium_gossypii LaVTCQIpldmgG------------geGKclYIDtEgtfrPiRlv Gallus_gallus LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Gibberella_zeae LaVTCQLpfdmgG------------geGKcmYIDtEgtfrPvRll Kluyveromyces_lactis LaVTCQIpldmgG------------geGKclYIDtEgtfrPiRlv Mus_musculus LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Neurospora_crassa LaVTCQLpfdmgG------------geGKclYIDtEgtfrPvRll Nosema_bombycis VaVTCQLppeqgG------------anGKalYIDtEgtfrseRff Oikopleura_dioica LaVTaQLpvdlgG------------geGKalYIDtEgtfrPeRll Oryctolagus_cuniculus LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Pichia_angusta LaVTCQLpidngG------------geGKclYIDtEgtfrPiRlv Pleurotus_ostreatus LaVTCQLpvsmgG------------geGKclYIDtEgtfrPvRll Rattus_norvegicus LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Schizosaccharomyces_pombe LaVTCQLpidmgG------------geGKclYIDtEgtfrPvRll Strongylocentrotus_purpuratus MaVTCQLpidngG------------geGKclYIDtEgtfrPeRli Tetraodon_nigroviridis LaVTCQLpidqgG------------geGKamYIDtEgtfrPeRll Ustilago_maydis LaVTCQLpvdmgG------------geGKclYIDtEntfrPtRll Xenopus_laevis LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Xenopus_tropicalis LaVTCQLpidrgG------------geGKamYIDtEgtfrPeRll Yarrowia_lipolytica LaVTCQLpidqgG------------geGKclYIDtEgtfrPeRlh Cryptosporidium_spp LaVTCQLpvehkG------------geGKclWIDtEgtfrPeRiv Dictyostelium_discoideum LcVTCQLgysqgG------------geGRalYIDtEgtfrPeRll Entamoeba_histolytica LcVTCQLgiengG------------teGRaiYIDtEgtfrPeRlt Leishmania_donovani LcVTCQLpisqgG------------aeGmalYIDtEgtfrPeRlv Leishmania_tropica LcVTCQLpisqgG------------aeGmalYIDtEgtfrPeRlv Plasmodium_berghei LaITCQLpieqsG------------geGKclWIDtEgtfrPeRiv Plasmodium_falciparum LaITCQLpieqsG------------geGKclWIDtEgtfrPeRiv Plasmodium_yoelii LaITCQLpieqsG------------geGKclWIDtEgtfrPeRiv Tetrahymena_thermophila LcITCQLpkekgG------------geGKamYIDtEgtfrPeRle Theileria_annulata LaVTCQLpveqsG------------geGKclWVDsEgtfrPeRiv Theileria_parva LaVTCQLpveqsG------------geGKclWVDsEgtfrPeRiv Trypanosoma_brucei LcVTCQLplsqgG------------geGmalYIDtEgtfrPeRlv Trypanosoma_cruzi LcVTCQLpisqgG------------aeGmalYIDtEgtfrPeRlv Arabidopsis_thaliana LcVTCQLpmdqgG------------geGKamYIDaEgtfrPqRll Oryza_sativa LcVTCQLpldqgG------------geGKalYIDaEgtfrPqRll Zea_mays LcVTCQLpldqgG------------geGKalYIDaEgtfrPqRll =============================================================================== ECOLI ViaaaQre------------------gktcaFIDaEhaldPiyar MYCOBACTERIUM_SMEGMATIS avaNaQaa------------------gGiaaFIDaEhaldPeyak MYCOBACTERIUM_TUBERCULOSIS avaNaQaa------------------gGvaaFIDaEhaldPeyak Acetobacter_polyoxogenes aiaeaQrk------------------gGtcaFIDaEhaldPgyar Acinetobacter_calcoaceticus aiaqCQka------------------gGtcaFIDaEhaldPqyar Actinobacillus_pleuropneumoniae ViaqaQks------------------gktcaFIDaEhaldPvyar Actinobacillus_succinogenes ViaqaQka------------------gkvcaFIDaEhaldPiyaa Bacillus_licheniformis aiaevQqq------------------gGQaaFIDaEhaldPvyaq Bacillus_subtilis aiaevQqq-------------------rtsaFIDaEhaldPvyaq Burkholderia_fungorum ViaemQki------------------gGtaaFIDaEhaldiqyas Carboxydothermus_hydrogenoformans IiaeaQkm------------------gGiaaFIDaEhaldPvyaq Chromobacterium_violaceum avaeaQkl------------------gGtcaYIDaEnaldPvyaq Clostridium_thermocellum IiaeaQka------------------gGEaaFIDaEhaldPvyak Colwellia_psychrerythraea ViaeaQrn------------------gkvcaFIDaEhaldPvyae Desulfotalea_psychrophila VvaeaQkl------------------gGiaaFIDaEhaldtayae Enterococcus_faecalis aiaevQrn------------------gGtaaFIDaEhaldPqyae Erwinia_carotovora ViaaaQre------------------gktcaFIDaEhaldPiyak Haemophilus_ducreyi ViaqaQri------------------gktcaFIDaEhaldPvyar Haemophilus_influenzae ViaqaQka------------------gktcaFIDaEhaldPiyaa Histophilus_somni ViaqaQka------------------gktcaFIDaEhaldPiyaa Kineococcus_radiotolerans avaSaQka------------------gGiaaFIDaEhaldPdyaa Leifsonia_xyli aiaNaQra------------------gGiaaFIDaEhaldPdyar Listeria_monocytogenes aiaevQaq------------------gGtaaFIDaEhaldPayak Mannheimia_succiniciproducens ViaqaQka------------------gkvcaFIDaEhaldPiyaa Neisseria_gonorrhoeae avaqCQkn------------------gGvcaFVDaEhafdPvyar Nitrosomonas_europaea aiaemQkl------------------gGtaaFIDaEhaldPqyaq Nitrosomonas_eutropha ViaemQkl------------------gGtaaFIDaEhaldPqyaq Oceanobacillus_iheyensis aiaeaQkq------------------gGQaaFIDaEhaldPvyak Pasteurella_multocida LiaaaQre------------------gktcaFIDaEhaldPvyak Photobacterium_profundum ViaSaQka------------------gktcaFIDaEhaldPiyaq Photorhabdus_luminescens ViaaaQre------------------gktcaFIDaEhaldPiyak Proteus_mirabilis ViaSaQre------------------gkicaFIDaEhaldPiyaq Pseudomonas_aeruginosa ViaeaQrq------------------gltcaFVDaEhaldPiyaa Pseudomonas_cepacia ViaelQkl------------------gGtaaFIDaEhaldvqyaa Salmonella_typhi ViaaaQre------------------gktcaFIDaEhaldPvyar Shewanella_putrefaciens ViaaaQre------------------gktcaFIDaEhaldPiyak Streptomyces_avermitilis avaNaQka------------------gGQvaFVDaEhaldPeyak Streptomyces_coelicolor avaNaQka------------------gGQvaFVDaEhaldPeyak Streptomyces_lividans avaNaQka------------------gGQvaFVDaEhaldPeyak Vibrio_cholerae LiaaaQre------------------gktcaFIDaEhaldPvyak Vibrio_splendidus LiaaaQrv------------------gktcaFVDaEhaldPiyaq Vibrio_vulnificus LiaaaQre------------------gktcaFIDaEhaldPvyak Xanthomonas_vasicola aiaqCQkl------------------gGtaaFIDaEhaldPvyaa Xylella_fastidiosa aiaqCQkk------------------gGtaaFIDaEhaldPiyag Yersinia_pestis ViaaaQre------------------gktcaFIDaEhaldPiyak =============================================================================== DEINOCOCCUS_RADIODURANS ntdellVsqpdnGeqaleimellvr--sg------a-idvvvvds Deinococcus_geothermalis ntdellVsqpdnGeqaleimellvr--sg------a-idvvvvds Thermus_aquaticus dvqellVsqpdtGeqaleivellar--sg------a-vdvivvds =============================================================================== Consensus lxiscQlxxxxxgxxxxxxxxxxxxxxgqxxfINxExxxxpxrxx