100 110 120 130 ----:----|----:----|----:----|----:----|----: Consensus xxxxxxxxxRQfxVxGNWKMNgnKxnLxELIxxLNxxxxxxxxxx ============================================================================= YEAST --------aRtFfVgGNFKLNGSKqSIkEIVerLNt-asip--en Candida_albicans --------aRQFfVgGNFKaNGtKqqItsIIdnLNk-adlp--kd Candida_glabrata --------aRtFfVgGNFKLNGtKkSIkEIVdrLNt-aslp--en Debaryomyces_hansenii --------aRQFfVgGNFKMNGtReSVsKIVdgLNk-aelp--sn Eremothecium_gossypii --------aRtFfVgGNFKLNGSKqSIkEIVerLNt-adla--dn Kluyveromyces_lactis --------aRtFfIgGNFKMNGtKaSIkEIVerLNs-asip--sn Yarrowia_lipolytica --------sRtFfVgGNFKMNGSleSIkaIVerLNa-seld--pk Zygosaccharomyces_bailii --------aRtFfVgGNFKLNGtKsSIkEIVerLNn-akld--pk ============================================================================= CHICKEN -----a-p-RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad C_ELEGANS -----t---RKFfVgGNWKMNGDyaSVdgIVtfLNa-sadn--ss HUMAN --gsap-s-RKFfVgGNWKMNGrKqSLgELIgtLNa-akvp--ad RABBIT -----a-psRKFfVgGNWKMNGrKkNLgELIttLNa-akvp--ad 1SPQA_Chicken ---------RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1SPQB_Chicken -----a-p-RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1SQ7A_Chicken -----a-p-RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1SSDA_Chicken -----a-p-RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1SU5A_Chicken -----a-p-RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1SW3A_Chicken -----a-p-RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1SW7A_Chicken ---------RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1TPB1_Chicken ---------RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1TPC1_Chicken ---------RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1TPUA_Chicken ---------RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1TPVA_Chicken ---------RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad 1TPWA_Chicken ---------RKFfVgGNWKMNGDKkSLgELIhtLNg-akls--ad Acipenser_brevirostrum -----a-ptRKFfVgGNWKLNGDKkSLgELIhtLNs-gkin--ad Anopheles_gambiae -------g-RKFcVgGNWKMNGDKaSItELcktLSa-gpld--pn Bos_taurus -----a-psRKFfVgGNWKMNGrKnNLgELIntLNa-akvp--ad Caenorhabditis_briggsae -------a-RKFfVgGNWKMNGDfaSVdgIVafLNq-sadn--sn Canis_lupus -----a-psRKFfVgGNWKMNGrKkNLgELIttLNa-akvp--ad Danio_rerio -----s-g-RKFfVgGNWKMNGDKkSIeELantLNs-akln--pd Drosophila_melanogaster snsnnm-s-RKFcVgGNWKMNGDQkSIaEIaktLSs-aald--pn Drosophila_pseudoobscura tnskms-a-RKFcVgGNWKMNGDQkSIaEIcktLSg-aald--pn Latimeria_chalumnae -----a-p-RKFfVgGNWKMNGDKkSLgELIqtLNa-akvp--ft Macaca_mulatta -----a-psRKFfVgGNWKMNGrKqNLgELIgtLNa-akvp--ad Mus_musculus -----a-ptRKFfVgGNWKMNGrKkcLgELIctLNa-anvp--ag Oryzias_latipes -----a-q-RRFfVgGNWKMNGNKeSLeELMstLNt-aslh--ed Pongo_pygmaeus -----a-psRKFfVgGNWKMNGrKqSLgELIgtLNa-akvp--ad Rattus_norvegicus -----a-psRKFfVgGNWKMNGrKkcLgELIctLNa-aklp--ad Schistosoma_mansoni ----sg-s-RKFfVgGNWKMNGSRdDndKLLklLSe-ahfd--dn Strongylocentrotus_purpuratus ----as-g-RRFwVgGNYKMNGSKaSIdgLLkmLee-sqip--gn Sus_scrofa -----a-paRKFfVgGNWKMNGrKnNLgELIntLNa-aklp--ad Xenopus_laevis -----s-p-RKFfVgGNWKMNGDKkSLgELIntLNs-gkmn--ad ============================================================================= ENTAMOEBA_HISTOLYTICA ------g-agKFvVgGNWKcNGtlaSIetLtkgVaasvdaelakk ============================================================================= LEISHMANIA_MEXICANA -----sa-kpQpiaaaNWKcNGttaSIeKLVqvfNe-htis--hd TRYPANOSOMA_BRUCEI ------s-kpQpiaaaNWKcNGSQqSLsELIdlfNs-tsin--hd TRYPANOSOMA_CRUZI -----as-kpQpiaaaNWKcNGSEslLvpLIetLNa-atfd--hd 1KV5A_Trypanosoma_brucei ------s-kpQpiaaaNWKcNGSQqSLsELIdlfNs-tsin--hd 1MSSA_Trypanosoma_brucei ------s-kpQpiaaaNWKcNGSQqSLsELIdlfNs-tsin--hd 1TRI0_Trypanosoma_brucei ------s-kpQpiaaaNW---GSQqSLsELIdlfNs-tsin--hd 1TTI0_Trypanosoma_brucei ------s-kpQpiaaaNWK------SLsELIdlfNs-tsin--hd 1TTJ0_Trypanosoma_brucei ------s-kpQpiaaaNW-------SLsELIdlfNs-tsin--hd Leishmania_donovani -----ss-kpQpiaaaNWKcNGttaSIeKLVqvLNe-hnis--hd Leishmania_tropica -----sa-kpQpiaaaNWKcNGttaSIeKLVqvLNe-hnis--hd ============================================================================= PLASMODIUM_FALCIPARUM -----a---RKYfVaaNWKcNGtleSIksLtnsfNn-ldfd-psk 1VGAB_Plasmodium_falciparum ---------RKYfVaaNWKcNGtleSIksLtnsfNn-ldfd-psk Plasmodium_berghei -----a---RKYfVsaNWKcNGtEySIksLadsfNt-vdfd-psk Plasmodium_chabaudi -----a---RKYfVsaNWKcNGtKdSIktLadsfNt-vdfd-psk Plasmodium_yoelii --------------------------------------------- ============================================================================= ECOLI ---------RhplVmGNWKLNGSRhmVhELVsnLrk-elag-vag VIBRIO_MARINUS ---------RhpvVmGNWKLNGSKemVvDLLngLNa-eleg-vtg Actinobacillus_pleuropneumoniae ---a-----RRplVmGNWKLNGSKaftkELIagLka-elad-vkg Actinobacillus_succinogenes --as-----RKplVmGNWKLNGSKaftrELIegLkt-elag-veg Erwinia_carotovora ---------RhplVmGNWKLNGStnlVnELIagLrk-elst-vdg Haemophilus_ducreyi ---a-----RRplVmGNWKLNGSKaftqQLIaeLkt-elae-itg Haemophilus_influenzae ---a-----RRplVmGNWKLNGSKaftkELIegLka-elhd-vtg Histophilus_somni ---a-----RRplVmGNWKLNGSKaftkELItgLkd-elna-vsg Mannheimia_succiniciproducens ---a-----RRplVmGNWKLNGSKaftkELIegLka-elag-veg Pasteurella_multocida ---------RRpvVmGNWKLNGSKamVtELLtgLNa-eleg-veg Photobacterium_profundum wrktm----RhpvVmGNWKLNGSKemVvnLLngLNa-eleg-vtg Photorhabdus_luminescens ---------RhplVmGNWKLNGSthmVnELItgLrq-elss-vtg Salmonella_typhi ---------RhplVmGNWKLNGSRhmVnELVanLrk-eltg-vag Vibrio_cholerae ---------RRpvVmGNWKLNGSKamVtDLLngLNa-eleg-veg Vibrio_fischeri ---------RhpvVmGNWKLNGSKemVvELLngLNa-eleg-vtg Vibrio_vulnificus ---------RRpvVmGNWKLNGSKtmVaELLtgLNa-eleg-veg Yersinia_pestis ---------RhplVmGNWKLNGSthmVnELIagLrk-elst-vdg ============================================================================= THERMUS_AQUATICUS ---------RRvlVaGNWKMHktpsearvwfaeLkr-llpp--lq ============================================================================= BACILLUS_STEAROTHERMOPHILUS ---------RKpiIaGNWKMHktlaeavQfVedVkg-hvpp-ade Bacillus_subtilis ---------RKpiIaGNWKMNktlgeavsfVeeVks-sipa-adk Geobacillus_kaustophilus ---------RKriIaGNWKMHktlaeavQfVenVkg-hvpp-ade ============================================================================= Consensus xxxxxxxxxRQfxVxGNWKMNgnKxnLxELIxxLNxxxxxxxxxx