320 330 340 350 360 ----|----:----|----:----|----:----|----:----| Consensus iNexIAEqLRIiYGGSVSxxNaxELxxQPDVDGfLVGGASLExpe ============================================================================= YEAST LgDkaAsELRILYGGSaNgsNAvtfkdKaDVDGFLVGGASLK-PE Candida_albicans IgaeqAEKtRILYGGSVNgkNAkDfkdKaNVDGFLVGGASLK-PE Candida_glabrata LgKdtAEKtRILYGGSaNgaNAgtfkdKaDVDGFLVGGASLK-PE Debaryomyces_hansenii IgadaAEKtRILYGGSVNgkNApEfkdKaDVDGFLVGGASLK-PE Eremothecium_gossypii tSrdVADaVRILFGGSaNgaNAasfrdKaDVDGFLVGGASLK-PE Kluyveromyces_lactis LSKdtAEKIRILYGGSaNgkNAvtfkdKaDVDGFLVGGASLK-PE Yarrowia_lipolytica Igaq-ADKVRIIYGGSVNgkNsgtfkdKsDVDGFLVGGASLK-PE Zygosaccharomyces_bailii LgEktAQEtRILYGGSaNgkNAvtfkdKPDVDGFLVGGASLK-PE ============================================================================= CHICKEN VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE C_ELEGANS VSpaVADatRIIYGGSVTadNAaELgkKPDIDGFLVGGASLK-PD HUMAN VSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE RABBIT VSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE 1SPQA_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1SPQB_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1SQ7A_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1SSDA_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1SU5A_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1SW3A_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1SW7A_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1TPB1_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1TPC1_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1TPUA_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1TPVA_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE 1TPWA_Chicken VSDaVAQstRIIYGGSVTggNckELasQhDVDGFLVGGASLK-PE Acipenser_brevirostrum VSEeVggaVRIIYGGSVTaatckELasKPDVDGFLVGGASLK-PE Anopheles_gambiae VSadVsnaIRIqYGGSVTaaNcrELaaKPDIDGFLVGGASLK-PE Bos_taurus VSDaVAQsaRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE Caenorhabditis_briggsae VSpaVADatRIIYGGSVTadNAaELgkKPDIDGFLVGGASLK-PD Canis_lupus VSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE Danio_rerio VSEaVAnsVRIIYGGSVTggtckELasQkDLDGFLVGGASLK-PE Drosophila_melanogaster ISKeVsasLRIqYGGSVTaaNAkELakKPDIDGFLVGGASLK-PE Drosophila_pseudoobscura ISKeVsaaLRIqYGGSVTaaNAkELakKPDIDGFLVGGASLK-PE Latimeria_chalumnae VSEtVADsVRIIYGGSVTgatckELasEPDVDGFLVGGASLK-PE Macaca_mulatta VSEaVAQstRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE Mus_musculus VNDgVAQstRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE Oryzias_latipes ISEeVsDsLRIIYGGSVTaaNcrELasQtDVDGFLVGGASLK-PE Pongo_pygmaeus VSDaVAQstRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE Rattus_norvegicus VSEgVAQctRIIYGGSVTgatckELasQPDVDGFLVGGASLK-PE Schistosoma_mansoni apngVdEKIRIIYGGSVTaaNckELaqQhDVDGFLVGGASLK-PE Strongylocentrotus_purpuratus VNaaVAantRIVYGGSVNggNccDIgqQPDVDGFLVGGASLK-PE Sus_scrofa VpEaVAhstRIIYGGSVTgatckELasQPDVDGFrVsGASLK-PE Xenopus_laevis VSEgVAQsVRIIYGGSVTggtcrELagQPDIDGFLVGGASLK-PE ============================================================================= ENTAMOEBA_HISTOLYTICA ISKeVAEatRIqYGGSVNpaNcnELakKaDIDGFLVGGASLDaaK ============================================================================= LEISHMANIA_MEXICANA IgtdVAaKLRILYGGSVNaaNAatLyaKPDINGFLVGGASLK-PE TRYPANOSOMA_BRUCEI IgadVAgELRILYGGSVNgkNArtLyqQrDVNGFLVGGASLK-PE TRYPANOSOMA_CRUZI LgtdIAaQLRILYGGSVTakNArtLyqmrDINGFLVGGASLK-PE 1KV5A_Trypanosoma_brucei IgadVAgELRILYGGSVNgkNArtLyqQrDVNGFLVGGASLK-PE 1MSSA_Trypanosoma_brucei IgadVAgELRILYGGSVNgkNArtLyqQrDVNGFLVGGASLK-PE 1TRI0_Trypanosoma_brucei IgadVAgELRILYGGSVNgkNArtLyqQrDVNGFLVGGASLK-PE 1TTI0_Trypanosoma_brucei IgadVAgELRILYGGSVNgkNArtLyqQrDVNGFLVGGASLK-PE 1TTJ0_Trypanosoma_brucei IgadVAgELRILYGGSVNgkNArtLyqQrDVNGFLVGGASLK-PE Leishmania_donovani IgadVAaRLRILYGGSVSagNAktLymKPDINGFLVGGASLK-PE Leishmania_tropica IgtdVAaKLRILYGGSVSagNAktLymKPDINGFLVGGASLK-PE ============================================================================= PLASMODIUM_FALCIPARUM cgEkqAnQIRILYGGSVNteNcssLiqQeDIDGFLVGnASLK-es 1VGAB_Plasmodium_falciparum cgEkqAnQIRILYGGSVNteNcssLiqQeDIDGFLVGnASLK-es Plasmodium_berghei cgEaqAnKIRILYGGSVSveNctsLikQeDIDGFLVGtsSLK-ts Plasmodium_chabaudi cgEaqAnKIRILYGGSVSveNctsLikQeDIDGFLVGtsSLK-ts Plasmodium_yoelii cgEaqAnKIRILYGGSVSveNctsLikQeDIDGFLVGtsSLK-ts ============================================================================= ECOLI -DanIAEQViIqYGGSVNasNAaELfaQPDIDGaLVGGASLKada VIBRIO_MARINUS -SEaVAKnVvIqYGGSVkpeNAaayfaQPDIDGaLVGGAaLDaks Actinobacillus_pleuropneumoniae -SQaVADQViIqYGGSVNdaNAaELftQPDIDGaLVGGASLKaPa Actinobacillus_succinogenes -SQaVADQViIqYGGSVNdaNAaELftQPDIDGaLVGGASLKaPa Erwinia_carotovora -DaaVAEQViIqYGGSVNaaNAaELftQPDIDGaLVGGASLKada Haemophilus_ducreyi -SQaVADQLiIqYGGSVNdtNAaELfsQPDIDGaLVGGASLKata Haemophilus_influenzae -SQaVAEQViIqYGGSVNdaNAaELftQPDIDGaLVGGASLKaPa Histophilus_somni -SQaVAERViIqYGGSVNdaNAaELftQPDIDGaLVGGASLKasa Mannheimia_succiniciproducens -SQaVADQViIqYGGSVNdaNAaELftQPDIDGaLVGGASLKaPa Pasteurella_multocida -DEaVAaQViIqYGGSVkpeNAeayfsQPDIDGaLVGGASLDaks Photobacterium_profundum -SEeVAKnLvIqYGGSVkpeNAaayfaQPDIDGaLVGGAaLDaks Photorhabdus_luminescens -DaaIAQQIiIqYGGSVNadNAaELfsQPDIDGaLVGGASLKana Salmonella_typhi -DakIAEQViIqYGGSVNasNAaELfaQPDIDGaLVGGASLKada Vibrio_cholerae -DaaVAEQViIqYGGSVkpeNAasyfaQPDIDGaLVGGASLDakg Vibrio_fischeri -SEeVAKnVvIqYGGSVkpeNAaayfaQPDIDGaLVGGAaLDaks Vibrio_vulnificus -DaaVAEQViIqYGGSVkpeNAeayfaQPDIDGaLVGGASLDaks Yersinia_pestis -DaaVAaQViIqYGGSVNdkNAaELftQPDIDGaLVGGASLKada ============================================================================= THERMUS_AQUATICUS ygEafAsRVRILYGGSVNpkNfaDLlsmPNVDGgLVGGASLEles ============================================================================= BACILLUS_STEAROTHERMOPHILUS fgpeaAEaIRIqYGGSVkpdNirDflaQqqIDGpLVGGASLEpas Bacillus_subtilis fSQeaADKLRIqYGGSVkpaNikEymaEsDIDGaLVGGASLEpqs Geobacillus_kaustophilus fgpeaAEaIRIqYGGSVkpdNirDflaQeqIDGaLVGGASLEpas ============================================================================= Consensus iNexIAEqLRIiYGGSVSxxNaxELxxQPDVDGfLVGGASLExpe