80 90 100 110 120 130 140 ----:----|----:----|----:----|----:----|----:----|----:----|----:----| Consensus lllpsstsDeELqhIrNsLpexxxsLkVqrIEeklTALgNlixcNDyvaLihpELerdtkKlxxxxxxxx ==================================================================================================== METHANOCOCCUS_JANNASCHII LLLPkiveDEELdrIKNfLkEnnldLnVEiIKsKnTALGNLIltNDkgALIsPELK-DfKKd-------- ==================================================================================================== YEAST LLVPTqTTDQELQHLRNSLPD---SVKIQRVEERLSALGNVIcCNDYVALVHPDIDRETEEL-------- Apis_mellifera LLVPNTTTDtELQHIRNSLPD---kVKVQRVEERLSALGNVIaCNDYVALVHPDLDRETEEI-------- Aspergillus_flavus LLVPTTTTDQELQHLRNTLPD---SVKIQRIEERLSALGNVIcCNDhVALIHPDLERETEEMyyphhhhc Aspergillus_fumigatus LLVPTTTTDQELQHLRNTLPD---dVKIQRIEERLSALGNVIcCNDhVALVHPDLERETEEI-------- Bos_taurus LLVPNNTTDQELQHIRNcLPD---SVQIRRVEERLSALGNVttCNDYVALVHPDLDRETEEI-------- Caenorhabditis_briggsae LLVPNaTTDQELQHLRNSLPD---eVaIRRVDERLSALGNVIaCNDhVAIVHaEIsaETEQa-------- Caenorhabditis_elegans LLVPNaTTDQELQHLRNSLPD---eVaIRRVDERLSALGNVIaCNDhVAIVHaEIsaETEQa-------- Candida_albicans LLVPTqTTDQELmHLRNSLPD---SIKIQRVEERLSALGNVIcCNDYVALVHPDIERETEEL-------- Candida_glabrata LLVPTqTTDQELQHLRNSLPD---SVKIQRVEERLSALGNVIcCNDYVALVHPDIDRETEEL-------- Canis_lupus LLVPNNTTDQELQHIRNcLPD---SVQIRRVEERLSALGNVttCNDYVALVHPDLDRETEEI-------- Cryptococcus_neoformans LLVPSSTTDQELQHLRNSLPp---TVaIQRVEERLSALGNVIaCNDYVALVHPDIDRETEEI-------- Danio_rerio LLVPNNTTDQELQHIRNcLPD---SVRIQRVEERLSALGNVIaCNDYVALVHPDLDRETEEI-------- Debaryomyces_hansenii LLVPTqTTDQELmHLRNSLPD---TVKIQRVEERLSALGNVIcCNDYVALVHPDIERETEEL-------- Drosophila_melanogaster LLVPNSTTDEELQHLRNSLPD---aVKIyRVEERLSALGNVIaCNDYVALVHPDLDKETEEI-------- Drosophila_pseudoobscura LLVPNSTTDEELQHLRNSLPD---aVKIQRVEERLSALGNVVaCNDYVALVHPDLDKETEEI-------- Emericella_nidulans LLVPTTTTDQELQHLRNTLPD---dVKIQRIEERLSALGNVIcCNDhVALIHPDLERETEEI-------- Eremothecium_gossypii LLVPTqTTDQELQHLRNSLPD---SVKIQRIEERLSALGNVIcCNDYVALVHPDIDnETEEL-------- Gallus_gallus LLVPSSTTDQELQHIRNSLPD---SVRIQRVEERLSALGNVttCNDYVALVHPDLDRETEEI-------- Gibberella_zeae LLVPTTTTDQELQHLRNSLPD---SVRIQRIEERLSALGNVIvtNDhIALVHPDLERETEEI-------- Homo_sapiens LLVPNNTTDQELQHIRNSLPD---TVQIRRVEERLSALGNVttCNDYVALVHPDLDRETEEI-------- Kluyveromyces_lactis LLVPTqTTDQELQHLRNcLPD---aVKVQRVEERLSALGNVIcCNDYVALVHPDIDRETEEL-------- Mus_musculus LLVPNNTTDQELQHIRNSLPD---SVQIRRVEERLSALGNVttCNDYVALVHPDLDRETEEI-------- Neurospora_crassa LLVPTTTSDQELQHLRNSLPD---dVRIQRIEERLSALGNVIvCNDhtALIHPDLERETEEI-------- Rattus_norvegicus ywyPTTTTDQELQHIhDSLlD---SVQIRRVEEgLSALdNVttCNDYVALVHPDLDRETEEI-------- Schistosoma_japonicum LLVPhTTTDQELlHLtNSLPD---NIRVmRIEERLSALGNtMaCNDYVALVHPDLDKETaEL-------- Schizosaccharomyces_pombe LLVPSSTTDnELQHLRNSLPD---pVKIQRVDERLSALGNIVaCNDYVALVHPDIERETEEI-------- Strongylocentrotus_purpuratus LLVPNSTTDQELQHIRNSLPD---SVKIQRIEEKLSALGNVIsCNDYVALVHPDLEKETEEI-------- Ustilago_maydis LLVPSTTTDQELQHLRNSLPE---SVaIQRVEERLSALGNVIaCNDYVALVHPDLDRETEEI-------- Xenopus_laevis LMVPNNTTDQELQHMRNSLPD---SVRIQRVEERLSALGNVIaCNDYVALVHPDLDRETEEI-------- Xenopus_tropicalis LMVPNNTTDQELQHIRNSLPD---SVRIQRVEERLSALGNVIaCNDYVALVHPDLDRETEEI-------- Yarrowia_lipolytica LLVPSTTSDvELQHLRNSLPD---eVKIQRVEERLSALGNVIctNDYaALVHPDIERETEEL-------- Bigelowiella_natans LLVPSTTrEnELKHLRNSLPD---kVKVQRIEEKLSALGNcVvaNDhVALVHPDIDQNTEEL-------- Dictyostelium_discoideum LLLPNTcTDQELQqIRNSLPD---dVvVQRIEEKfSALGNcIatNDYVALVHPDIDRETEEI-------- Plasmodium_berghei LLVsSicTDQELlHLRNSLPD---NVKIKRIEERLSALGNcItCNDYVgLIHtDIDRETEEI-------- Plasmodium_chabaudi LLVsSicTDQELlHLRNSLPD---dVKIKRVEERLSALGNcItCNDYVgLIHtDIDRETEEI-------- Plasmodium_falciparum LLVsSicTDQELlHLRNcLPE---NVKIKRIEERLSALGNcIttNDYVgLIHtDIDKETEEI-------- Plasmodium_yoelii LLVsSicTDQELlHLRNSLPD---NVKIKRVEERLSALGNcItCNDYVgLIHtDIDRETEEI-------- Arabidopsis_thaliana LLVPhTTTDQELQHLRNSLPD---qVvVQRIDERLSALGNcIaCNDYVALaHtDLDKETEEI-------- Oryza_sativa LLLPhTTTDQELQHLRNcLPD---qVvVQRIDERLSALGNcVaCNDhVALtHPDLDKaTEEL-------- ==================================================================================================== Consensus lllpsstsDeELqhIrNsLpexxxsLkVqrIEeklTALgNlixcNDyvaLihpELerdtkKlxxxxxxxx